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Skin Abscess

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141. Thoughts from the bedside on antibiotics and I&D for abscesses

at 2:23 PM There was a really nicely done RCT on clinda vs bactrim vs no antibiotics for simple skin abscesses done in NEJM just recently. Great study – may be more benefit to abx (especially clinda in kids) than what I was taught. Comments are closed. Archives Archives Links @PEMTweets on Twitter © 2012-19 PEMBlog | All Rights Reserved | (...) Thoughts from the bedside on antibiotics and I&D for abscesses Thoughts from the bedside on antibiotics and I&D for abscesses – PEMBlog Search for: Search for: | 2017-08-29T14:09:37-04:00 August 29th, 2017 | , | Share this post About the Author: Related Posts February 27th, 2019 February 12th, 2019 January 30th, 2019 January 9th, 2019 January 8th, 2019 December 17th, 2018 December 13th, 2018 December 12th, 2018 November 27th, 2018 November 23rd, 2018 One Comment Benjamin Kinnear August 29, 2017

2017 PEM Blog

142. Randomized trial comparing wound packing to no wound packing following incision and drainage of superficial skin abscesses in the pediatric emergency department. (Abstract)

Randomized trial comparing wound packing to no wound packing following incision and drainage of superficial skin abscesses in the pediatric emergency department. The objective of this study was to investigate the impact of wound packing versus no wound packing on short-term failure rates and long-term recurrences after incision and drainage (I&D) of a simple cutaneous abscess.In this randomized, single-blind, prospective study, subjects between the ages 1 and 25 years with skin abscesses (...) needing an I&D were enrolled consecutively and randomized to be packed or not packed following the procedure. Treatment failure was assessed at a 48-hour follow-up visit by a masked observer who rated the need for a major intervention (repeat I&D or re-exploration) or minor intervention (antibiotics initiated or changed, need for packing, or repeat visit). Pain scores were assessed using color analog scales before and after the procedure and repeated at the 48-hour follow-up visit. Healing and abscess

2012 Pediatric Emergency Care Controlled trial quality: uncertain

143. Nasal tip abscess due to adverse skin reaction to Prolene: an unusual long term complication of rhinoplasty. (Abstract)

Nasal tip abscess due to adverse skin reaction to Prolene: an unusual long term complication of rhinoplasty. Allergic reactions to Prolene are rare. This paper reports a nasal tip abscess which developed in a patient with an adverse skin reaction to Prolene after rhinoplasty.A 26-year-old woman presented with painful, progressive nasal tip swelling and redness. She had undergone septo-rhinoplasty two years previously. She was initially treated with endonasal drainage of the abscess (...) and antibiotics, but a revision rhinoplasty three months later became necessary because of recurrent abscess formation. Intra-operative findings included granulation tissue with pockets of pus and knotted Prolene sutures at the tip-defining points of the lower lateral cartilages. She was patch-tested with Prolene and a cutaneous Prolene suture was placed on her back; an adverse skin reaction was seen for the latter.Use of non-absorbable sutures, such as Prolene, in the subcutaneous layer may be a potential

2012 Journal of Laryngology & Otology

144. Clinical and Epidemiologic Characteristics as Predictors of Treatment Failures in Uncomplicated Skin Abscesses within Seven Days after Incision and Drainage. (Abstract)

Clinical and Epidemiologic Characteristics as Predictors of Treatment Failures in Uncomplicated Skin Abscesses within Seven Days after Incision and Drainage. Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is now the leading cause of superficial abscesses seen in the Emergency Department.Our primary aim was to determine if an association exists between three predictor variables (abscess size, cellulitis size, and MRSA culture) and treatment failure within 7 days after (...) incision and drainage in adults. Our secondary aim was to determine if an association exists between two clinical features (abscess size and size of surrounding cellulitis) and eventual MRSA diagnosis by culture.Logistic regression models were used to examine clinical variables as predictors of treatment failure within 7 days after incision and drainage and MRSA by wound culture.Of 212 study participants, 190 patients were analyzed and 22 were lost to follow-up. Patients who grew MRSA, compared

2012 Journal of Emergency Medicine Controlled trial quality: uncertain

145. Emergency department visit rates for abscess versus other skin infections during the emergence of CA-MRSA, 1997-2007. Full Text available with Trip Pro

Emergency department visit rates for abscess versus other skin infections during the emergence of CA-MRSA, 1997-2007. Due to a flaw in the International Classification of Diseases, Ninth Revision, Clinical Modification coding system, epidemiology of skin and soft-tissue infections (SSTIs) has conflated abscess with other SSTIs. We analyzed emergency department visits during 1997-2007, finding that the odds of abscess relative to any other diagnosis increased 11% per year, or 3.1-fold, whereas

2012 Clinical Infectious Diseases

146. Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus Full Text available with Trip Pro

Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus Staphylococcus aureus is the leading cause of skin and skin structure infections (SSSI). The high frequency of recurring SSSI due to S. aureus, including methicillin-resistant S. aureus (MRSA) strains, despite high titers of specific antibodies and circulating T cells, implies that traditional adaptive immunity imparts incomplete protection (...) . We hypothesized that innate immune memory contributes to the protective host defense against recurring MRSA infection. To test this hypothesis, SSSI was induced in wild-type and rag1-/- mice in the BALB/c and C57BL/6 backgrounds. Prior infection (priming) of wild-type and rag1-/- mice of either background afforded protection against repeat infection, as evidenced by reduced abscess severities and decreased CFU densities compared to those in naive controls. Interestingly, protection was greater

2017 Infection and immunity

147. Management of acute bacterial skin and skin structure infections with a focus on patients at high risk of treatment failure Full Text available with Trip Pro

Management of acute bacterial skin and skin structure infections with a focus on patients at high risk of treatment failure Over the last 25 years, the terminology of skin and soft tissue infections, as well as their classification for optimal management of patients, has changed. The so-called and recently introduced term 'acute bacterial skin and skin structure infections' (ABSSSIs), a cluster of fairly common types of infection, including abscesses, cellulitis, and wound infections, require

2017 Therapeutic advances in infectious disease

148. Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

a written informed consent Subjects with ABSSSI characterized by any of the following infection types: Cellulitis/erysipelas: diffuse skin infection characterized by spreading areas of redness, edema, and/or induration Wound infection: An infection characterized by purulent drainage from a wound with surrounding redness, edema, and/or induration Major cutaneous abscess: An infection characterized by a collection of pus within the dermis or deeper that is accompanied by redness, edema, and/or induration (...) Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save

2017 Clinical Trials

149. A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer (...) to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018) The safety and scientific validity of this study is the responsibility

2017 Clinical Trials

150. Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections

Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03137173 Recruitment Status

2017 Clinical Trials

151. An extremely rare case of tubo-ovarian abscesses involving corynebacterium striatum as causative agent. Full Text available with Trip Pro

was treated with antibiotic therapy and surgery to remove the left adnexa. Various cultures detected Prevotella spp. and C. striatum. We concluded that C. striatum from skin contaminated by psoriasis vulgaris had caused the tubo-ovarian abscesses by way of ascending infection.This may be the first known case of tubo-ovarian abscesses due to C. striatum. In patients whose skin has been weakened by psoriasis vulgaris or other infections, Corynebacterium should be considered as causative microorganisms (...) An extremely rare case of tubo-ovarian abscesses involving corynebacterium striatum as causative agent. We present an extremely rare case of tubo-ovarian abscesses involving Corynebacterium striatum (C. striatum) as causative agent in a 53-year-old woman.The patient presented with stomach pain, chills, and nausea. Her medical history included poorly controlled psoriasis vulgaris and diabetes. Laboratory and imaging findings led to diagnosis of septic shock due to tubo-ovarian abscesses. She

2016 BMC Infectious Diseases

152. Dermatophyte abscesses caused by Trichophyton rubrum in a patient without pre-existing superficial dermatophytosis: a case report. Full Text available with Trip Pro

Dermatophyte abscesses caused by Trichophyton rubrum in a patient without pre-existing superficial dermatophytosis: a case report. Trichophyton usually causes a superficial skin infection, affecting the outermost layer of the epidermis, the stratum corneum. In immunocompromised patients, deeper invasion into the dermis and even severe systemic infection with distant organ involvement can occur. Most cases of deeper dermal dermatophytosis described in the literature so far involved pre-existing (...) dextrose agar. Histopathology showed organizing abscesses with degenerated fungal hyphae. After the 12-week oral itraconazole therapy, the lesions were completely resolved.Dermatophytes should be considered as a possible cause of deep soft tissue abscesses in immunocompromised patients, even though there is no superficial dermatophytosis lesion.

2016 BMC Infectious Diseases

153. Primary cellulitis and cutaneous abscess caused by Yersinia enterocolitica in an immunocompetent host: A case report and literature review. Full Text available with Trip Pro

Primary cellulitis and cutaneous abscess caused by Yersinia enterocolitica in an immunocompetent host: A case report and literature review. Primary extraintestinal complications caused by Yersinia enterocolitica are extremely rare, especially in the form of skin and soft-tissue manifestations, and little is known about their clinical characteristics and treatments. We presented our case and reviewed past cases of primary skin and soft-tissue infections caused by Y enterocolitica. We report (...) a case of primary cellulitis and cutaneous abscess caused by Y enterocolitica in an immunocompetent 70-year-old woman with keratodermia tylodes palmaris progressiva. She presented to an outpatient clinic with redness, swelling, and pain of the left ring finger and left upper arm without fever or gastrointestinal symptoms 3 days before admission. One day later, ulceration of the skin with exposed bone of the proximal interphalangeal joint of the left ring finger developed, and cefditoren pivoxil

2016 Medicine

154. Bacillary angiomatosis presenting with facial tumor and multiple abscesses: A case report. Full Text available with Trip Pro

Bacillary angiomatosis presenting with facial tumor and multiple abscesses: A case report. The clinical manifestation of bacillary angiomatosis (BA) can be limited to one organ, most commonly the skin, but systemic courses can also occur. We report a human immunodeficiency virus (HIV)-positive patient with a systemic manifestation of BA caused by Bartonella quintana, diagnosed in Vienna, Austria. The pathogen was detected in multiple organs including a facial tumor which is an unusual finding (...) for BA. Furthermore, infections with B quintana are rare in our area and no other autochthonous cases have been reported.The clinical manifestation included multiple papules and nodules on the entire body, several organic abscesses, and a facial tumor influencing the patient's view.The main laboratory finding indicated HIV infection combined with severe immunosuppression with 47 CD4 cells/μL. Contrast-enhanced computed tomography of the chest and the abdomen showed multiple and abscesses

2016 Medicine

155. Diabetic foot complicated by vertebral osteomyelitis and epidural abscess Full Text available with Trip Pro

Diabetic foot complicated by vertebral osteomyelitis and epidural abscess Vertebral osteomyelitis (or spondylodiscitis) is steadily increasing in Western countries and often results from hematogenous seeding, direct inoculation during spinal surgery, or contiguous spread from an infection in the adjacent soft tissue. We present the case of a 67-year-old white patient with type 2 diabetes who went to Hospital for high fever, back pain, and worsening of known infected ulcers in the left foot (...) . Despite intravenous antibiotic treatment and surgical debridement of the foot infection, high fever and lower back pain continued. Bone biopsy and two consecutive blood cultures were positive for Staphylococcus aureus. A spinal magnetic resonance imaging (MRI) was performed, revealing serious osteomyelitis in L4 and L5 complicated by an epidural abscess. Contiguous or other distant focuses of infection were not identified. In this case, diabetic foot could be considered as a primary distant focus

2016 Endocrinology, diabetes & metabolism case reports

156. Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation Full Text available with Trip Pro

Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation Staphylococcus aureus is a major bacterial pathogen, which causes severe blood and tissue infections that frequently emerge by autoinfection with asymptomatically carried nose and skin populations. However, recent studies report that bloodstream isolates differ systematically from those found in the nose and skin, exhibiting reduced toxicity toward leukocytes (...) via SSR42, a long-noncoding RNA. We show that rsp controls SSR42 expression, is induced by hydrogen peroxide, and is required for normal cytotoxicity and hemolytic activity. Rsp inactivation in laboratory- and bacteremia-derived mutants attenuates toxin production, but up-regulates other immune subversion proteins and reduces lethality during experimental infection. Crucially, inactivation of rsp preserves bacterial dissemination, because it affects neither formation of deep abscesses in mice nor

2016 Proceedings of the National Academy of Sciences of the United States of America

157. A study assessing postoperative Corrugate Rubber drain of perianal abscess Full Text available with Trip Pro

2015. 67 patients in group A were managed by Corrugated Rubber drain and 70 patients in group B were managed by packing. In group A, males were 92.53% more than females (7.46%) while group B, males were 85.71% and the rest were females. Outcome measures were assessed; time to cavity healing, pain scoring, abscess recurrence, fistula formation, analgesic requirement and skin disfigurement.The mean time of abscess healing in group A and B were 8.50 ± 0.49 and 8.90 ± 0.23 days respectively. Their pain (...) A study assessing postoperative Corrugate Rubber drain of perianal abscess Perianal abscess which can lead to a devastating complications. The management of perianal abscess involves incision and drainage by different methods one of them is packing the cavity.The aim is using Corrugate Rubber drain as an alternative to other methods.This study was an observational retrospective review of 137 'case series' of patients with perianal abscess over a fifteen-year period from January 2000 to December

2016 Annals of Medicine and Surgery

158. Perisigmoid Abscess Leading to a Diagnosis of Ehlers-Danlos Syndrome Type IV Full Text available with Trip Pro

Perisigmoid Abscess Leading to a Diagnosis of Ehlers-Danlos Syndrome Type IV The Ehlers-Danlos syndromes (EDS) are a group of connective tissue disorders characterized by triad of joint hypermobility, skin extensibility, and tissue fragility. Ehlers-Danlos syndrome type IV places patients at risk for life-threatening, spontaneous, vascular or visceral rupture due to reduced or abnormal secretion of type III collagen. We present an adolescent male who was found to have a perisigmoid abscess

2016 ACG case reports journal

159. PBP-2 Negative Methicillin Resistant Staphylococcus schleiferi Bacteremia from a Prostate Abscess: An Unusual Occurrence Full Text available with Trip Pro

PBP-2 Negative Methicillin Resistant Staphylococcus schleiferi Bacteremia from a Prostate Abscess: An Unusual Occurrence Staphylococcus schleiferi subsp. schleiferi is a coagulase-negative Staphylococcus which has been described as a pathogen responsible for various nosocomial infections including bacteremia, brain abscess, and infection of intravenous pacemakers. Recently, such bacteria have been described to be found typically on skin and mucosal surfaces. It is also believed to be a part (...) have been reported about prostatic abscess (PA) with this microbe. Our patient had a history of recurrent UTIs and subsequent PA resulting in S. schleiferi bacteremia in contrast to gram negative bacteremia commonly associated with UTI. This organism was found to be resistant to methicillin, in spite of being negative for PBP2, which is a rare phenomenon and needs further studies.

2016 Case reports in infectious diseases

160. Male Breast Abscess Secondary to Actinomycosis: A Case Report Full Text available with Trip Pro

Male Breast Abscess Secondary to Actinomycosis: A Case Report Primary breast actinomycosis is a rare condition that has been previously reported in the female breast. Male breast infection is uncommon and most often associated with trauma to the skin or predisposing conditions like diabetes. We report the first case to our knowledge of primary breast actinomycosis in the male breast caused by Actinomycesneuii (A. neuii), a rare strain of Actinomyces. Mammography demonstrated periareolar skin

2016 Journal of clinical and diagnostic research : JCDR

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