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Skin Abscess

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61. Sutures v staples for skin closure in lower limb orthopaedic surgery: A Rapid Review

% confidence interval) with hip surgeries. (1) Knee orthopaedic surgery For knee surgery, there is no difference in rates of wound infection between sutures and staples (Figure 3). (1) Specifically, there is no difference in superficial infection (Figure 4), deep infection (Figure 5), abscess formation (Figure 6), wound dehiscence (Figure 7), or prolonged wound discharge (Figure 7). (3) It should be noted that Kim et al., (3) conclude that skin sutures had a higher likelihood of superficial and deep (...) Sutures v staples for skin closure in lower limb orthopaedic surgery: A Rapid Review Sutures vs staples for lower limb orthopaedic surgery: A Rapid Review 1 Sutures v staples for skin closure in lower limb orthopaedic surgery: A Rapid Review Citation Joseph, C. & Melder, A. March 2018. Sutures versus staples for skin closure in lower limb orthopaedic surgery: A Rapid Review. Centre for Clinical Effectiveness, Monash Health, Melbourne, Australia. Executive Summary Background & Objective

2019 Monash Health Evidence Reviews

62. Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula in Ano, and Rectovaginal Fistula

locations. 7–11 a norectal abscess occurs more often in males than females, and may occur at any age, with peak incidence among 20 to 40 year olds. 4,8–12 in general, the abscess is treated with prompt incision and drainage. 4,6,10,13 fistula-in-ano is a tract that connects the perine- al skin to the anal canal. in patients with an anorec- tal abscess, 30% to 70% present with a concomitant fistula-in-ano, and, in those who do not, one-third will be diagnosed with a fistula in the months to years after (...) Clinical Practice Guideline for the Management of Anorectal Abscess, Fistula in Ano, and Rectovaginal Fistula Copyright © The American Society of Colon & Rectal Surgeons, Inc. Unauthorized reproduction of this article is prohibited. 1117 Diseases of the Colon & ReCtum Volume 59: 12 (2016) t he a merican society of Colon and Rectal sur- geons is dedicated to ensuring high-quality pa- tient care by advancing the science, prevention, and management of disorders and diseases of the co- lon, rectum

2016 American Society of Colon and Rectal Surgeons

63. The Massachusetts abscess rule: a clinical decision rule using ultrasound to identify methicillin-resistant Staphylococcus aureus in skin abscesses. (PubMed)

The Massachusetts abscess rule: a clinical decision rule using ultrasound to identify methicillin-resistant Staphylococcus aureus in skin abscesses. Treatment failure rates for incision and drainage (I&D) of skin abscesses have increased in recent years and may be attributable to an increased prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). Previous authors have described sonographic features of abscesses, such as the presence of interstitial fluid (...) , characteristics of abscess debris, and depth of abscess cavity. It is possible that the sonographic features are associated with MRSA and can be used to predict the presence of MRSA. The authors describe a potential clinical decision rule (CDR) using sonographic images to predict the presence of CA-MRSA.This was a pilot CDR derivation study using databases from two emergency departments (EDs) of patients presenting to the ED with uncomplicated skin abscesses who underwent I&D and culture of the abscess

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2014 Academic Emergency Medicine

64. Adalimumab (Hyrimoz) - Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Rheumatoid Arthritis, Ulcerative Colitis, Crohn Disease, Papulosquamous Skin Diseases, Hidradenitis Suppurativa, Ankylosing Spondylitis, Uveitis

used topical antiseptic wash daily. Clinical Response Reduction of inflammatory lesions and prevention of worsening of abscesses and draining fistulas was assessed using Hidradenitis Suppurativa Clinical Response (HiSCR; at least a 50 % reduction in total abscess and inflammatory nodule count with no increase in abscess count and no increase in draining fistula count relative to Baseline). Reduction in HS-related skin pain was assessed using a Numeric Rating Scale in patients who entered the study (...) Adalimumab (Hyrimoz) - Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Rheumatoid Arthritis, Ulcerative Colitis, Crohn Disease, Papulosquamous Skin Diseases, Hidradenitis Suppurativa, Ankylosing Spondylitis, Uveitis 1 ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 2 This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 for how

2018 European Medicines Agency - EPARs

65. What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department?

and Soft Tissue Infections in the Emergency Department? x Michael Gottlieb , MD, RDMS (EBEM Commentator) , x Ananda Vishnu Pandurangadu , MD (EBEM Commentator) Department of Emergency Medicine, Rush University Medical Center, Chicago, IL DOI: | Publication History Published online: March 15, 2017 Expand all Collapse all Article Outline Take-Home Message Point-of-care ultrasonographic examination of skin and soft tissue infections enhances the ability to differentiate abscesses from cellulitis. Methods (...) Data Sources The authors searched MEDLINE, Web of Science, Cumulative Index to Nursing and Allied Health Literature, EMBASE, and Cochrane Libraries from inception through May 21, 2015, using Medical Subject Headings terms and corresponding key words to capture the concepts of ultrasonography, abscess, cellulitis, and skin and soft tissue infections. Additional searches were performed on , EBSCO discovery tool, and Google Scholar. No language restriction was applied. Gray literature searches were

2017 Annals of Emergency Medicine Systematic Review Snapshots

66. What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department?

What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department? TAKE-HOME MESSAGE Point-of-care ultrasonographic examination of skin and soft tissue infections enhances the ability to differentiate abscesses from cellulitis. What Is the Utility of Ultrasonography for the Identi?cationofSkinandSoftTissueInfectionsinthe Emergency Department? EBEM Commentators Michael Gottlieb, MD, RDMS Ananda Vishnu Pandurangadu, MD Department (...) to capture the concepts of ultrasonography, abscess, cellulitis, and skin and soft tissue infections.Additionalsearcheswere performed on clinicaltrials.gov, EBSCO discovery tool, and Google Scholar.Nolanguagerestrictionwas applied. Gray literaturesearches were conducted by soliciting unpublished trials and manually searching all references of full-text articlesreviewedandabstractsfrom major emergency medicine and ultrasonographic conferences. To obtain additional information about trial design

2017 Annals of Emergency Medicine Systematic Review Snapshots

67. Do Oral Antibiotics After Incision and Drainage of Simple Abscesses Improve Cure Rates?

the need for hospitalization or operating room drainage. Clinical cure was de?ned as improvement or resolution of signs and symptoms without concerns for treatmentfailure.Two independent investigators screened for articles meeting the inclusion criteria. ANNALS OF EMERGENCY MEDICINE JANUARY 2015 112 Annals of Emergency Medicine Volume 65, no. 1 : January 2015approximately 3.2% of all ED visits. 2 Twenty-two percent of new skin infection visits were for abscess. 2 In one study, 63% of abscesses were (...) abscesses: a meta-analysis. Emerg Med J. http://dx.doi.org/10.1136/emermed-2013- 202571. 1. Schmitz GR, Bruner D, Pitotti R, et al. Randomized controlled trial of trimethoprim-sulfamethoxazole for uncomplicated skin abscesses in patients at risk for community-associated methicillin- resistant Staphylococcus aureus infection. Ann Emerg Med. 2010;56: 283-287. 2. Pallin DJ, Camargo CA Jr, Schuur JD. Skin infections and antibiotic stewardship: analysis of emergency department prescribing practices, 2007

2015 Annals of Emergency Medicine Systematic Review Snapshots

68. Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre, randomised, controlled, non-inferiority trial. (PubMed)

Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre, randomised, controlled, non-inferiority trial. Pathogen resistance and safety concerns limit oral antibiotic options for the treatment of acute bacterial skin and skin structure infections (ABSSSI). We aimed to compare the efficacy and safety of once-daily oral omadacycline, an aminomethylcycline antibiotic, versus twice-daily (...) or erysipelas, or major abscess) and receipt (yes or no) of allowed previous antibacterial treatment. Investigators, funders, and patients were masked to treatment assignments. Primary endpoints were early clinical response, 48-72 h after first dose, in the modified intention-to-treat (mITT) population (randomised patients without solely Gram-negative ABSSSI pathogens at baseline), and investigator-assessed clinical response at post-treatment evaluation, 7-14 days after the last dose, in the mITT population

2019 Lancet infectious diseases

69. Omadacycline for Acute Bacterial Skin and Skin Structure Infections. (PubMed)

(ABSSSI). Omadacycline in Acute Skin and Skin Structure Infections Study 1 (OASIS-1) initiated patients on intravenous omadacycline or linezolid, with the option to transition to an oral formulation after day 3. OASIS-2 was an oral-only study of omadacycline versus linezolid.In total, 691 patients received omadacycline and 689 patients received linezolid. Infection types included wound infection in 46.8% of patients, cellulitis/erysipelas in 30.5%, and major abscess in 22.7%. Pathogens were identified (...) Omadacycline for Acute Bacterial Skin and Skin Structure Infections. Within the last decade, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a frequent cause of purulent skin and soft tissue infections. New therapeutic options are being investigated for these infections.We report an integrated analysis of 2 randomized, controlled studies involving omadacycline, a novel aminomethylcycline, and linezolid for the treatment of acute bacterial skin and skin structure infections

2019 Clinical Infectious Diseases

70. Comparison of Minimally Invasive Loop Drainage and Standard Incision and Drainage of Cutaneous Abscesses in Children Presenting to a Pediatric Emergency Department: A Prospective, Randomized, Noninferiority Trial. (PubMed)

Comparison of Minimally Invasive Loop Drainage and Standard Incision and Drainage of Cutaneous Abscesses in Children Presenting to a Pediatric Emergency Department: A Prospective, Randomized, Noninferiority Trial. This study aimed to determine whether the treatment of skin abscesses with vessel loop drainage is noninferior to standard incision and drainage (I&D) regarding treatment failure in pediatric patients in the emergency department (ED).This study was a prospective, randomized controlled (...) trial in a pediatric ED of an urban tertiary pediatric hospital. Patients with a skin abscess were enrolled. Subjects were assigned to the control arm of I&D or the study arm of vessel loop drainage. Study end points (failure rates, satisfaction scores, wound appearance, visit frequency) were assessed before discharge from the ED, at 24- to 48-hour follow-up, and at 14-day follow-up. Treatment failure was declared if the abscess required reinstrumentation or admission for intravenous antibiotics

2019 Pediatric Emergency Care

71. Pilot Study to Evaluate the Adjunct Use of a Povidone-Iodine Topical Antiseptic in Patients with Soft Tissue Abscesses. (PubMed)

Pilot Study to Evaluate the Adjunct Use of a Povidone-Iodine Topical Antiseptic in Patients with Soft Tissue Abscesses. Povidone-iodine (PVP-I) antiseptic solutions have been shown to be effective against methicillin-resistant Staphylococcal aureus, a common cause of superficial skin abscesses.Our objective was to study the feasibility of using PVP-I as a treatment adjunct in patients with superficial skin abscesses and determine if it confers any benefit over incision and drainage (I&D (...) ) alone.This was a randomized controlled pilot study of adult patients with an uncomplicated skin abscess. Patients were randomized to PVP-I or standard treatment. All patients had I&D and abscess packing. Patients randomized to PVP-I were instructed on daily application of the agent to hands, wound, and surrounding skin with dressing changes. Subjects returned at 48-72 h and 7-10 days and followed-up by phone at 30 days. The primary outcome was clinical cure 7-10 days after I&D. The secondary outcomes

2019 Journal of Emergency Medicine

72. A Novel Silicon Device for the Packing of Cutaneous Abscesses. (PubMed)

A Novel Silicon Device for the Packing of Cutaneous Abscesses. Superficial skin abscesses are commonly encountered in emergency medicine practice. Standard treatment includes incision, drainage, and often packing with a gauze strip. The packing component of the procedure has several negative potential outcomes, is painful, and necessitates a return visit for removal.Here we report the first case in which a novel silicon packing device was utilized. The patient presented with a facial abscess

2019 Journal of Emergency Medicine

73. Spinal epidural abscess caused by Pasteurella multocida mimicking aortic dissection: a case report. (PubMed)

Spinal epidural abscess caused by Pasteurella multocida mimicking aortic dissection: a case report. Pasteurella multocida (P. multocida) forms part of the normal flora of many animals. Although it is a common causative agent of skin and soft tissue infection after an animal bite or scratch, in rare cases it can cause spinal infections in humans.A 68-year-old immunocompetent woman presented with fever and sudden onset of severe back pain mimicking aortic dissection. No findings related (...) to the pain were revealed on enhanced computed tomography or initial magnetic resonance imaging (MRI) of the spine. The patient was found to be bacteremic with P. multocida, although she had no apparent injury related to animal contact. Repeated evaluation by MRI with gadolinium-contrast established the diagnosis of spinal epidural abscess. The patient was cured by the rapid initiation of antimicrobial therapy without surgery.We describe the successful treatment of an individual with a spinal epidural

2019 BMC Infectious Diseases

74. Randomised controlled trial: Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses

Randomised controlled trial: Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses Article Text Therapeutics Randomised controlled

2010 Evidence-Based Medicine (Requires free registration)

75. CRACKCast E137 – Skin Infections

, and surgical consultation. Emergency clinicians should be familiar with toxic shock syndromes and Rocky Mountain spotted fever, which are rare, life-threatening, skin infection–related syndromes. Lyme disease should be considered in endemic areas. For the management of most skin abscesses, antibiotics are not recommended. Adequate analgesia or sedation are essential to good patient care. There is debate about the necessity of wound culture and Gram staining. Current recommendations for the treatment (...) -Clav Erythema migrans Borrelia burgdorferi Doxycycline Puncture wound through foot Pseudomomas aeruginosa Ciprofloxacin [1] List 6 risk factors for cellulitis From Uptodate: Predisposing factors for development of cellulitis and/or skin abscess include: Skin barrier disruption due to trauma (such as abrasion, penetrating wound, pressure ulcer, venous leg ulcer, insect bite, injection drug use) Skin inflammation (such as eczema, radiation therapy) Edema due to impaired lymphatic drainage Edema due

2017 CandiEM

76. Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis

, such as: recurrent boils or abscesses, previous MRSA infection and underlying medical conditions, close contact with others with the infection and also skin trauma such as scrapes, tattoos, injection drug use, shaving and/or sharing equipment that is not sterilized. Many people who get MRSA have no risk factors. Topical therapy with mupirocin 2% is a treatment option for MRSA if there are no signs of systemic infection, however there is a high resistance level and treatment failure associated with this use. MRSA (...) Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis The skin has an effective

2017 medSask

77. The LOOP technique: a novel incision and drainage technique in the treatment of skin abscesses in a pediatric ED. (PubMed)

The LOOP technique: a novel incision and drainage technique in the treatment of skin abscesses in a pediatric ED. This study assesses outcome in pediatric patients with skin abscess using the LOOP compared to the standard incision and drainage (I&D) with packing method.This retrospective study used ICD-9 codes to identify pediatric patients aged 0 to 17 years with a skin abscess presenting to a level I pediatric trauma emergency department (ED). Patients requiring surgical debridement were (...) to confirm these results, but this novel technique shows promise as an alternative to I&D with packing in the management of skin abscesses in pediatric ED patients.Copyright © 2014 Elsevier Inc. All rights reserved.

2015 American Journal of Emergency Medicine

78. The utility of adjunctive antibiotics for the management of skin and soft tissue abscesses after incision and drainage

The utility of adjunctive antibiotics for the management of skin and soft tissue abscesses after incision and drainage Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence

2018 PROSPERO

79. “More than skin deep”: Recurrent primary hand abscesses in a warehouse operative (PubMed)

“More than skin deep”: Recurrent primary hand abscesses in a warehouse operative A 25-year-old male right-hand dominant warehouse operator presented with two hand infections within 12 weeks both requiring surgical drainage and antimicrobial therapy. Subsequent testing confirmed Panton-Valentine leukocidin-positive Staphylococcus aureus (PVL-SA). This case highlights the need for prompt multidisciplinary management of hand infections to consider, diagnose and manage atypical infections.

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2015 Case Reports in Plastic Surgery & Hand Surgery

80. Serum biomarkers of Burkholderia mallei infection elucidated by proteomic imaging of skin and lung abscesses (PubMed)

Serum biomarkers of Burkholderia mallei infection elucidated by proteomic imaging of skin and lung abscesses The bacterium Burkholderia mallei is the etiological agent of glanders, a highly contagious, often fatal zoonotic infectious disease that is also a biodefense concern. Clinical laboratory assays that analyze blood or other biological fluids are the highest priority because these specimens can be collected with minimal risk to the patient. However, progress in developing sensitive assays (...) the tissue sections, a more extensive proteomic analysis was performed by a technique that combined the physical separation capabilities of liquid chromatography (LC) with the sensitive mass analysis capabilities of mass spectrometry (LC-MS/MS). By examining standard formalin-fixed, paraffin-embedded tissue sections, this strategy resulted in the identification of several proteins that were associated with lung and skin abscesses, including the host protein calprotectin and the pathogen protein GroEL

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2015 Clinical proteomics

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