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Skin Abscess

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61. Staphylococcus lugdunensis from gluteal abscess to destructive native triple valve endocarditis Full Text available with Trip Pro

Staphylococcus lugdunensis from gluteal abscess to destructive native triple valve endocarditis We herein present the case of a 43-year-old male diabetic patient who presented with an aggressive form of infective endocarditis involving the tricuspid, mitral and aortic valves following a gluteal abscess due to infection with Staphylococcus lugdunensis. This coagulase-negative organism which is generally considered a component of the normal flora of the skin has however recently emerged

2018 Saudi medical journal

62. Methicillin-resistant Staphylococcus aureus prostatic abscess after traumatic rectal injury Full Text available with Trip Pro

Methicillin-resistant Staphylococcus aureus prostatic abscess after traumatic rectal injury Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection of the skin, soft tissue, bones and heart. MRSA is a rarely reported organism of prostatic abscess (PA). We present a case of an intravenous drug user who presented with dyspareunia, dysuria and dyschezia after a traumatic injury to the rectum. He was diagnosed with PA, which was treated with transurethral resection (...) of the prostate drainage and intravenous antibiotics. MRSA PA carries a low case fatality rate on early diagnosis and treatment with proper antibiotics with or without drainage of the abscess.

2018 Oxford Medical Case Reports

63. Spontaneous subconjunctival abscess in congenital lamellar ichthyosis Full Text available with Trip Pro

Spontaneous subconjunctival abscess in congenital lamellar ichthyosis Congenital lamellar ichthyosis is an autosomal recessive, heterogeneous disorder presenting at birth with generalized skin involvement. The most common ophthalmic manifestation noted is bilateral ectropion of the lower eyelids. A 1-month-old female neonate, the second born of a nonconsanguineous marriage, presented with 4 days' history of redness, discharge, and swelling in the right eye. There was severe right upper eyelid (...) ectropion, conjunctival injection, chemosis, a subconjunctival mass on the temporal bulbar conjunctiva spontaneously draining pus and corneal haze. The anterior chamber, iris, lens and fundus appeared normal. Congenital lamellar ichthyosis was suspected because of scaling and excessive dryness of the entire body. The occurrence of a spontaneous subconjunctival abscess is not known in lamellar ichthyosis. We thus report the management of a rare case of unilateral upper eyelid ectropion, subconjunctival

2018 Indian journal of ophthalmology

64. De-roofing and Curettage vs WLE for Pilonidal Abscess

links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Abscess de-roofing and curettage Abscess de-roofing and curettage. The patient will be placed in the lateral position with the buttocks spread apart using tape. The cleft of the buttocks will be shaved prior to cleaning and preparation of the skin. A spindle-shaped (elliptical) excision will be performed to the lateral aspect of the abscess formation (...) -roofing and curettage Abscess de-roofing and curettage Active Comparator: Abscess wide local excision Wide local excision. Patients will be placed in the prone position with the buttocks spread apart using tape. The cleft of the buttocks will be shaved prior to cleaning and preparation of the skin. Diluted methylene blue will be injected in all visible pits and a wide spindle-shaped (elliptical) midline excision of the skin and the underlying subcutaneous tissue down to the coccygeal (pre-sacral

2018 Clinical Trials

65. Breast abscess caused by Staphylococcus aureus in 2 adolescent girls with atopic dermatitis Full Text available with Trip Pro

Breast abscess caused by Staphylococcus aureus in 2 adolescent girls with atopic dermatitis Atopic dermatitis (AD) is a chronic inflammatory skin disease in children. Patients with AD experience a high rate of colonization of the skin surface by Staphylococcus aureus. Because of a skin barrier defect, there is a potential risk of staphylococcal invasive infection in patients with AD. Here, we present 2 cases of breast abscess caused by S. aureus in 2 adolescent girls with severe AD. Methicillin (...) -sensitive S. aureus was identified from the breast abscess material. They were treated with appropriate antibiotics, however surgical drainage of the abscess was needed in case 1. Identical strains were found from the breast abscess material as well as the lesional and the nonlesional skin of the patients through matrixassisted laser desorption/ionization time-of-flight analysis. We characterized the differential abundance of Firmicutes phylum in patients' skin in microbiota analysis. In particular, S

2018 Korean journal of pediatrics

66. Successful treatment following early recognition of a case of Fournier’s scrotal gangrene after a perianal abscess debridement: a case report Full Text available with Trip Pro

for severe scrotal and perianal pain, swelling, and high fever. A physical examination revealed a perianal abscess. Furthermore, the scrotum was gangrenous and exhibited extensive cellulitis in the perineum and bilateral inguinal area. Crepitations between the skin and fascia were palpable. A diagnosis of Fournier's gangrene was made. The patient was treated with immediate surgical debridement under general anesthesia. He received broad-spectrum antibiotics, and debridement was repeated until the wound (...) Successful treatment following early recognition of a case of Fournier’s scrotal gangrene after a perianal abscess debridement: a case report Fournier's gangrene is an acute surgical emergency characterized by high mortality rates ranging from approximately 13% to 45%. Therefore, aggressive multidisciplinary management is necessary.A 29-year-old Asian man who had undergone surgical debridement at another hospital to treat a perianal abscess 5 days earlier was admitted to our hospital

2018 Journal of medical case reports

67. BET 1: Trimethoprim-sulfamethoxazole in uncomplicated skin abscess. (Abstract)

BET 1: Trimethoprim-sulfamethoxazole in uncomplicated skin abscess. A short cut review was carried out to establish whether incision and drainage followed by treatment with oral trimethoprim-sulfamethoxazole is better than incision and drainage alone at treating patients with uncomplicated skin abscesses. One hundred and ninety-seven papers were found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country (...) of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that trimethoprim-sulfamethoxazole may help with abscess cure, and will decrease abscess formation at new sites.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

2016 Emergency Medicine Journal

68. Point-of-Care Ultrasound for Diagnosis of Abscess in Skin and Soft Tissue Infections. Full Text available with Trip Pro

Point-of-Care Ultrasound for Diagnosis of Abscess in Skin and Soft Tissue Infections. Traditionally, emergency department (ED) physicians rely on their clinical examination to differentiate between cellulitis and abscess when evaluating skin and soft tissue infections (SSTI). Management of an abscess requires incision and drainage, whereas cellulitis generally requires a course of antibiotics. Misdiagnosis often results in unnecessary invasive procedures, sedations (for incision and drainage (...) in pediatric patients), or a return ED visit for failed antibiotic therapy.The objective was to describe the operating characteristics of point-of-care ultrasound (POCUS) compared to clinical examination in identifying abscesses in ED patients with SSTI.We systematically searched Medline, Web of Science, EMBASE, CINAHL, and Cochrane Library databases from inception until May 2015. Trials comparing POCUS with clinical examination to identify abscesses when evaluating SSTI in the ED were included. Trials

2016 Academic Emergency Medicine

69. Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess. Full Text available with Trip Pro

Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess. U.S. emergency department visits for cutaneous abscess have increased with the emergence of methicillin-resistant Staphylococcus aureus (MRSA). The role of antibiotics for patients with a drained abscess is unclear.We conducted a randomized trial at five U.S. emergency departments to determine whether trimethoprim-sulfamethoxazole (at doses of 320 mg and 1600 mg, respectively, twice daily, for 7 days) would be superior (...) to placebo in outpatients older than 12 years of age who had an uncomplicated abscess that was being treated with drainage. The primary outcome was clinical cure of the abscess, assessed 7 to 14 days after the end of the treatment period.The median age of the participants was 35 years (range, 14 to 73); 45.3% of the participants had wound cultures that were positive for MRSA. In the modified intention-to-treat population, clinical cure of the abscess occurred in 507 of 630 participants (80.5

2016 The New England journal of medicine Controlled trial quality: predicted high

70. Comparison of trimethoprim-sulfamethoxazole versus placebo for uncomplicated skin abscesses. Full Text available with Trip Pro

Comparison of trimethoprim-sulfamethoxazole versus placebo for uncomplicated skin abscesses. Clinical question In patients with uncomplicated abscesses receiving incision and drainage, does the addition of trimethoprim-sulfamethoxazole result in improved clinical resolution at 7 to 14 days after treatment when compared with placebo? Article chosen Talan DA, Mower WR, Krishnadasan A, et al. Trimethoprim-sulfamethoxazole versus placebo for uncomplicated skin abscess. N Engl J Med 2016;374(9):823 (...) -32.The primary objective of this study was to compare the clinical cure rates at 7 to 14 days after the end of the treatment period among patients receiving either trimethoprim-sulfamethoxazole (TMP-SMX) or placebo. Secondary outcomes included composite cure; surgical drainage procedures; change in erythema size; presence of swelling, induration, or tenderness; invasive infections; skin infections at the same site and different sites; hospitalizations; similar infections in household contacts

2016 CJEM

71. Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection Full Text available with Trip Pro

Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection Staphylococcus aureus produces numerous factors that facilitate survival in the human host. S. aureus coagulase (Coa) and von Willebrand factor-binding protein (vWbp) are known to clot plasma through activation of prothrombin and conversion of fibrinogen to fibrin. In addition, S. aureus clumping factor A (ClfA) binds fibrinogen and contributes (...) to platelet aggregation via a fibrinogen- or complement-dependent mechanism. Here, we evaluated the contribution of Coa, vWbp and ClfA to S. aureus pathogenesis in a rabbit model of skin and soft tissue infection. Compared to skin abscesses caused by the Newman wild-type strain, those caused by isogenic coa, vwb, or clfA deletion strains, or a strain deficient in coa and vwb, were significantly smaller following subcutaneous inoculation in rabbits. Unexpectedly, we found that fibrin deposition and abscess

2016 PloS one

72. A Prescription for Resistance: Management of Staphylococcal Skin Abscesses by General Practitioners in Australia Full Text available with Trip Pro

A Prescription for Resistance: Management of Staphylococcal Skin Abscesses by General Practitioners in Australia We investigated the management of staphylococcal abscesses (boils) by general practitioners (GPs) in the context of rising antibiotic resistance in community strains of Staphylococcus aureus.We analyzed patient-reported management of 66 cases of uncomplicated skin abscesses from the frequency matched methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA (...) was performed in only 60.6% of 66 patients, and antibiotics were always prescribed. The prescribed antibiotics were frequently inactive and often changed, and did not appear to affect patient recovery. Our results show that community GPs can confidently reduce their use of antibiotics for patients with skin abscesses and should be aware that MRSA is a much more common in this type of infection.

2016 Frontiers in microbiology

73. Community-Assoc. S. Aureus Colonization and Recurrent Infection in Pts With Uncomplicated S. Aureus Skin Abscesses

Community-Assoc. S. Aureus Colonization and Recurrent Infection in Pts With Uncomplicated S. Aureus Skin Abscesses Community-Assoc. S. Aureus Colonization and Recurrent Infection in Pts With Uncomplicated S. Aureus Skin Abscesses - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Community-Assoc. S. Aureus Colonization and Recurrent Infection in Pts With Uncomplicated S. Aureus Skin Abscesses (CIRCUS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02690415 Recruitment Status : Enrolling by invitation

2016 Clinical Trials

74. Primary Care Management of Skin Abscesses Guided by Ultrasound. Full Text available with Trip Pro

Primary Care Management of Skin Abscesses Guided by Ultrasound. Primary care providers often manage skin abscesses in the outpatient setting. Estimating the size and depth of an abscess, and distinguishing abscess from cellulitis by clinical examination can be challenging due to surrounding firm tissue induration. Definitive treatment of abscess requires incision and drainage, and the approach chosen may be altered by abscess size, depth, and surrounding neurovascular structures.For 31 (...) consecutive patients seen in the primary care outpatient clinic, we prospectively compared the estimated size of skin abscesses by clinical examination with that determined by ultrasound. Prior to incision and drainage, a limited point-of-care ultrasound examination was performed and the abscess dimensions were measured, the depth was determined, and adjacent vascular structures were noted. Based on ultrasound findings, physicians reported whether the decision to perform the procedure or the techniques

2016 American Journal of Medicine

75. “More than skin deep”: Recurrent primary hand abscesses in a warehouse operative Full Text available with Trip Pro

“More than skin deep”: Recurrent primary hand abscesses in a warehouse operative A 25-year-old male right-hand dominant warehouse operator presented with two hand infections within 12 weeks both requiring surgical drainage and antimicrobial therapy. Subsequent testing confirmed Panton-Valentine leukocidin-positive Staphylococcus aureus (PVL-SA). This case highlights the need for prompt multidisciplinary management of hand infections to consider, diagnose and manage atypical infections.

2015 Case Reports in Plastic Surgery & Hand Surgery

76. Safety and Tolerability Study of Antimicrobial TheraGauze for Skin Abscess

Safety and Tolerability Study of Antimicrobial TheraGauze for Skin Abscess Safety and Tolerability Study of Antimicrobial TheraGauze for Skin Abscess - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety (...) and Tolerability Study of Antimicrobial TheraGauze for Skin Abscess The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02334384 Recruitment Status : Completed First Posted : January 8, 2015 Results First Posted : August 29, 2018 Last Update Posted : October 4, 2018 Sponsor: Eastern Virginia Medical School

2015 Clinical Trials

77. The LOOP technique: a novel incision and drainage technique in the treatment of skin abscesses in a pediatric ED. (Abstract)

The LOOP technique: a novel incision and drainage technique in the treatment of skin abscesses in a pediatric ED. This study assesses outcome in pediatric patients with skin abscess using the LOOP compared to the standard incision and drainage (I&D) with packing method.This retrospective study used ICD-9 codes to identify pediatric patients aged 0 to 17 years with a skin abscess presenting to a level I pediatric trauma emergency department (ED). Patients requiring surgical debridement were (...) to confirm these results, but this novel technique shows promise as an alternative to I&D with packing in the management of skin abscesses in pediatric ED patients.Copyright © 2014 Elsevier Inc. All rights reserved.

2015 American Journal of Emergency Medicine

78. The cutaneous microbiome in out-patients presenting acutely with skin abscesses. Full Text available with Trip Pro

The cutaneous microbiome in out-patients presenting acutely with skin abscesses. Previous studies have demonstrated an association between antibiotic use and the development of skin abscesses. We tested the hypothesis that alterations in the composition of the cutaneous microbiota may predispose individuals to skin abscesses.We studied 25 patients with skin abscesses and 25 age-matched controls, who each completed a questionnaire. Skin swab samples were obtained for DNA analysis from 4 sites (...) -abscess and contralateral skin samples, compared with control skin specimens. Analysis of community structure showed greater heterogeneity in the control samples than in the peri-abscess and contralateral samples. Metagenomic analysis detected significantly more predicted genes related to metabolic activity in the peri-abscess specimens than in the control samples.The peri-abscess microbiome was similar to the contralateral microbiome, but both microbiomes differed from that for control patients. Host

2015 Journal of Infectious Diseases

79. Methicillin-Resistant Staphylococcus aureus: Decolonization and Prevention Prescribing Practices for Children Treated With Skin Abscesses/Boils in a Pediatric Emergency Department. Full Text available with Trip Pro

Methicillin-Resistant Staphylococcus aureus: Decolonization and Prevention Prescribing Practices for Children Treated With Skin Abscesses/Boils in a Pediatric Emergency Department. This study aimed to describe methicillin-resistant Staphylococcus aureus (MRSA) eradication/prevention practices of clinicians managing patients with skin and soft tissue infections (SSTIs), specifically, in those patients undergoing abscess incision and drainage (I&D) in a pediatric emergency department (ED (...) ).A retrospective cohort study was performed for children aged 0 to 18 years old undergoing I&D of cutaneous abscess between January 1, 2011, and December 31, 2011, in the Cincinnati Children's Hospital Medical Center ED.Five hundred seventy-five patients underwent abscess I&D during our study period. Approximately 25% of our population had previous history of MRSA, SSTI, or boil/abscess; in addition, 26% of our population had a household family member with a previous history of MRSA, SSTI, or boil/abscess

2015 Pediatric Emergency Care

80. Multiple Skin Abscesses and Myofibrosis of Bilateral Lower Limbs Following Repeated Intramuscular Injection of Pentazocine with Concomitant Tuberculous Infection Full Text available with Trip Pro

Multiple Skin Abscesses and Myofibrosis of Bilateral Lower Limbs Following Repeated Intramuscular Injection of Pentazocine with Concomitant Tuberculous Infection Prescription drug abuse is a major health problem across the globe. Various complications associated with repeated injection of pentazocine are reported in the literature, including skin fibrosis, skin abscesses and ulceration, abnormal skin pigmentation and fibrous myopathy.We present a case of 48 year male with history of pentazocine (...) abuse. Patient developed multiple abscesses in both lower limbs with polymicrobial infection, one of them being mycobacterium tuberculosis. He also developed fibrous myopathy leading to stiff hip and knee.This case highlights the significance of the precaution that should be taken when prescribing opioid analgesics, such as pentazocine, as routine painkillers. With free over the counter access to these drugs in India and many developing countries, awareness of this complication is important so

2015 Journal of orthopaedic case reports

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