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Skin Reaction to Cold

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1. Skin Reaction to Cold

Skin Reaction to Cold Skin Reaction to Cold Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Skin Reaction to Cold Skin Reaction (...) to Cold Aka: Skin Reaction to Cold From Related Chapters II. Conditions (Immersion foot) Acrocyanosis Erythrocyanosis Cryoglobulins Cold Sclerema neonatorum of the newborn Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Skin Reaction to Cold." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Effects of low temperature (C0161734) Concepts Injury

2018 FP Notebook

2. Cold Sore - Guidelines for Prescribing Oral Antivirals

persons and includes generalized swollen lymph nodes, especially in the neck and groin. Fever is also possible. Blisters may occur on the lips which resemble a cold sore lesion. Refer to patient's primary care provider for blood tests and diagnosis. - non-healing lesions which may resemble cold sores on face. Suspect this if the lesion has not healed or change over 10 days. - a fever causing, skin-peeling reaction in response to a drug. - a painless sore on the lips or in the mouth occurring 10 days (...) and the lesions will have honey-coloured crusts, contrast to the clear crusts seen with cold sores. - lesions that occur on the inside of lips and are not preceded by formation of a vesicle. Will not occur on external lip. - inflammation that occurs on the corners of the mouth, which can resemble a cold sore. However, angular cheilitis will not cause any lesions to form. - presence of typical lesions on skin and mucous membranes, spread to head, trunk and extremities. Lesions can occur rarely

2017 medSask

3. Sudden Onset of Cold, Painful Leg

exclusively on patients with chronic PAD. This includes asymptomatic PAD, leg pain with exertion (ie, intermittent claudication), and critical limb ischemia (CLI, defined as chronic leg or foot pain at rest, skin ulceration, or gangrene). By comparison, the literature focused on imaging patients with ALI is very limited. Consequently, the following discussion relies heavily on studies of patients with chronic PAD. Variant 1: Sudden onset of cold, painful leg. Arteriography Arteriography (digital (...) . There are also risks associated with iodinated contrast materials. Most worrisome are the rare fatal systemic reactions and contrast-induced nephropathy. The nephrotoxic effects are important to consider as many patients who present with the sudden onset of a cold, painful leg are elderly, diabetic, and have impaired renal function [10]. Carbon dioxide angiography or other imaging modalities that do not use iodinated contrast material should be considered in patients with estimated glomerular filtration rate

2016 American College of Radiology

4. Observations on Some Normal and Injurious Effects of Cold upon the Skin and Underlying Tissues: I. Reactions to Cold, and Injury of Normal Skin (PubMed)

Observations on Some Normal and Injurious Effects of Cold upon the Skin and Underlying Tissues: I. Reactions to Cold, and Injury of Normal Skin 20783993 2011 04 04 2011 04 04 0007-1447 2 4222 1941 Dec 06 British medical journal Br Med J Observations on Some Normal and Injurious Effects of Cold upon the Skin and Underlying Tissues: I. Reactions to Cold, and Injury of Normal Skin. 795-7 Lewis T T eng Journal Article England Br Med J 0372673 0007-1447 2010 8 27 6 0 1941 12 6 0 0 1941 12 6 0 1

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1941 British medical journal

5. Adalimumab (Hyrimoz) - Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Rheumatoid Arthritis, Ulcerative Colitis, Crohn Disease, Papulosquamous Skin Diseases, Hidradenitis Suppurativa, Ankylosing Spondylitis, Uveitis

Adalimumab (Hyrimoz) - Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Rheumatoid Arthritis, Ulcerative Colitis, Crohn Disease, Papulosquamous Skin Diseases, Hidradenitis Suppurativa, Ankylosing Spondylitis, Uveitis 1 ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 2 This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 for how (...) to report adverse reactions. 1. NAME OF THE MEDICINAL PRODUCT Hyrimoz 40 mg solution for injection in pre-filled syringe Hyrimoz 40 mg solution for injection in pre-filled pen 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Hyrimoz 40 mg solution for injection in pre-filled syringe: Each 0.8 ml single-dose pre-filled syringe contains 40 mg of adalimumab. Hyrimoz 40 mg solution for injection in pre-filled pen: Each 0.8 ml single-dose pre-filled pen contains 40 mg of adalimumab. Adalimumab is a recombinant

2018 European Medicines Agency - EPARs

6. Skin Reaction to Cold

Skin Reaction to Cold Skin Reaction to Cold Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Skin Reaction to Cold Skin Reaction (...) to Cold Aka: Skin Reaction to Cold From Related Chapters II. Conditions (Immersion foot) Acrocyanosis Erythrocyanosis Cryoglobulins Cold Sclerema neonatorum of the newborn Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Skin Reaction to Cold." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Effects of low temperature (C0161734) Concepts Injury

2015 FP Notebook

7. Association of human antigen class I genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean population. (PubMed)

Association of human antigen class I genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean population. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a spectrum of diseases that cause an acute vesiculobullous reaction in the skin and mucous membranes. The occurrence of these diseases is associated with various drugs, a large proportion of which is comprised cold medicines (CM). We try to investigate the association

2019 British Journal of Ophthalmology

8. Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis

or immunosuppression are common co-morbidities Slow to heal; high scarring potential Tinea corporis (ringworm) may form similar looking pustules, but has a clear central area surrounded by red, rash-like ring. Refer to Guideline for . Viral skin diseases such as , shingles or which may blister, but have a clear exudate. Herpes simplex or herpes zoster may resemble impetigo; however, the lesions are not honey-coloured. Cold sores usually occur singly around border of lips. Refer to Guideline for Chickenpox lesions (...) usually develop over the trunk and extremities as well as the face. Shingles follows are unilateral distribution along dermatome tracks typically affects interdigital and intertriginous areas. Intense nighttime itching. Ask about exposure to others with scabies. involves high fever with a severe rash and skin-peeling in reaction to a drug. which starts with a localized infection caused by toxins produced by certain strains of Staphylococcus aureus . When the blisters break the top layer of the skin

2017 medSask

9. Management of Infusion Reactions to Systemic Anticancer Therapy: ESMO Clinical Practice Guidelines

proteins [generally immunoglobulin E (IgE)-mediated allergic responses] or non-immune-mediated reactions [1]. Most IRs are mild with symptoms such as chills, fever, nausea, headache, skin rash, pruritus, etc. Severe reactions are less frequent and may be fatal without appropriate intervention. It is dif?cult to evaluate these reactions through prospective randomised studies because of the unexpected nature of these events. There is a lack of consensus in the terminology or grading of the severity (...) [18–20]. The more rapidly a reaction develops, the more severe it is likely to be. The CRS has a similar appearance to a type I HSR and may be clinically indistin- guishable. Most reactions are mild to moderate, with ‘in?uenza- like’ symptoms (fever, chills, muscular pain, rash, fatigue, head- ache, etc.) and appear within the ?rst couple of hours, most often with the ?rst infusion [21]. A characteristic side-effect of oxali- platin is acute laryngopharyngeal dysaesthesia, a cold-related sen

2017 European Society for Medical Oncology

10. Skin Reactions to Cold (PubMed)

Skin Reactions to Cold Although skin reactions to cold are seen surprisingly infrequently in Canada, it is important to manage them correctly when they do occur. Frostbite, cold urticarias, Raynaud's disease and phenomenon, and several miscellaneous changes are discussed.

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1976 Canadian Family Physician

11. Herbal Medicines for Cold Hypersensitivity in the Hands and Feet: A Systematic Review and Meta-Analysis. (PubMed)

medicine was found to be superior to placebo in increasing skin temperature and peripheral blood flow. Six participants exhibited minor adverse drug reactions. Herbal medicine showed a superior TER, especially when combined with Western medicine, to Western medicine alone or placebo. However, there was a high risk of bias within all studies.Although herbal medicine shows potential to be a safe and effective treatment for CHHF and RP, the high risk of bias in all studies prevents definitive conclusions (...) Herbal Medicines for Cold Hypersensitivity in the Hands and Feet: A Systematic Review and Meta-Analysis. Cold hypersensitivity in the hands and feet (CHHF) and Raynaud's phenomenon (RP) are prevalent among Asian populations, especially among women, who exhibit a higher rate of cold hypersensitivity that may be associated with gynecological problems. In several countries, herbal medicine has effectively treated cold hypersensitivity symptoms. This systematic review and meta-analysis

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2018 Journal of Alternative and Complementary Medicine

12. Effectiveness of Mechano-Analgesia and Cold Application on Ecchymosis, Pain and Satisfaction at Subcutaneous Heparin Injection

. Condition or disease Intervention/treatment Phase Injection Site Reaction Injection Site Bruising Device: ShotBlocker Device: Ice pack Not Applicable Detailed Description: The abdomen was divided into four quarters. The first, second, and third SC heparin injections were applied from the right abdominal region using ShotBlocker®, left abdominal region with an ice pack, and lower abdominal region without any additional application, respectively. All the injection sites were circled using a skin marking (...) Coagulation Disorders Hematologic Diseases Hemorrhage Pathologic Processes Skin Manifestations Signs and Symptoms Extravasation of Diagnostic and Therapeutic Materials Drug-Related Side Effects and Adverse Reactions Chemically-Induced Disorders Heparin Calcium heparin Anticoagulants Fibrinolytic Agents Fibrin Modulating Agents Molecular Mechanisms of Pharmacological Action

2018 Clinical Trials

13. Antipruritic Effect of Cold-induced and Transient Receptor Potential-agonist-induced Counter-irritation on Histaminergic Itch in Humans. (PubMed)

-induced itch, wheals and neurogenic inflammation in 13 healthy volunteers. Histamine 1% was applied to the volar forearms using skin prick-test lancets. Recorded outcome-parameters were itch intensity, wheal reactions, and neurogenic inflammation (measured by laser-speckle perfusion-imaging). Homotopic thermal counter-irritation was performed with 6 temperatures, ranging from 4°C to 37°C, using a 3 × 3-cm thermal stimulator. Chemical "cold-like" counter-irritation was conducted with 40% L-menthol (...) and 10% trans-cinnamaldehyde, while 5% doxepin was used as a positive antipruritic control/comparator. Cold counter-irritation stimuli from 4°C to 22°C inhibited itch in a stimulus-intensity-dependent manner (p < 0.05) and, to a lesser extent, also wheal reactions and neurogenic inflammation. Chemical "cold-like" counter-irritation with both L-menthol and trans-cinnamaldehyde had antipruritic efficacy similar to doxepin (p < 0.05). Cold-induced counter-irritation had an inhibitory effect

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2017 Acta Dermato-Venereologica

14. Time-Dependent Effects of Acute Exercise on University Students’ Cognitive Performance in Temperate and Cold Environments (PubMed)

university students (age 23.5 ± 2.0 years) with moderate physical activity level participated in a repeated-measures within-subjects design. Processing speed, working memory and cognitive flexibility were assessed using CogState test battery at baseline (BASE), followed by a 45-min rest (REST), immediately after (EX) and 30 min after (POST-EX) 30-min moderate-intensity treadmill running in both temperate (TEMP; 25°C) and cold (COLD; 10°C) environments. Mean skin temperature (MST) and thermal sensation (...) (TS) were also recorded. Two-way repeated measures ANOVA was performed to analyze each variable. Spearman's rho was used to identify the correlations between MST, TS and cognitive performance. Results: Reaction time (RT) of processing speed and working memory decreased immediately after exercise in both conditions (processing speed: p = 0.003; working memory: p = 0.007). The facilitating effects on processing speed disappeared within 30 min after exercise in TEMP (p = 0.163) and COLD (p = 0.667

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2017 Frontiers in psychology

15. Genetics of Skin Cancer (PDQ®): Health Professional Version

Genetics of Skin Cancer (PDQ®): Health Professional Version Genetics of Skin Cancer (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002 (...) -. Search term Genetics of Skin Cancer (PDQ®) Health Professional Version PDQ Cancer Genetics Editorial Board . Published online: February 14, 2019. Created: July 29, 2009 . This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the genetics of skin cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care

2018 PDQ - NCI's Comprehensive Cancer Database

16. Skin Cancer Treatment (PDQ®): Health Professional Version

reaction may cause substantial skin toxicity and discomfort in a large proportion of patients. Imiquimod topical therapy Imiquimod is an agonist for the toll-like receptor 7 and/or 8, inducing a helper T-cell cytokine cascade and interferon production. It purportedly acts as an immunomodulator. Although imiquimod is an FDA-approved treatment for superficial BCCs, some investigators in the field do not recommend it for initial monotherapy for BCC; some reserve its use for patients with small lesions (...) Skin Cancer Treatment (PDQ®): Health Professional Version Skin Cancer Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002

2017 PDQ - NCI's Comprehensive Cancer Database

17. Cold-induced Systemic Reactions Caused by Infusion of Intravenous Fluid. (PubMed)

Cold-induced Systemic Reactions Caused by Infusion of Intravenous Fluid. 23321995 2013 10 17 2015 11 19 1651-2057 93 4 2013 Jul 06 Acta dermato-venereologica Acta Derm. Venereol. Cold-induced systemic reactions caused by infusion of intravenous fluid. 469-70 10.2340/00015555-1494 Park Hee Jung HJ Park So-Young SY Lee Seo Hyun SH Kim Ga Hee GH Yang Jee Eun JE Yoon Sun Young SY Kim Su-Jeong SJ Kwon Hyouk-Soo HS Cho You Sook YS Moon Hee-Bom HB Kim Tae-Bum TB eng Case Reports Letter Sweden Acta (...) Derm Venereol 0370310 0001-5555 451W47IQ8X Sodium Chloride IM Anaphylaxis diagnosis drug therapy etiology Cold Temperature adverse effects Female Fluid Therapy adverse effects Humans Infusions, Intravenous Predictive Value of Tests Skin Tests Sodium Chloride administration & dosage adverse effects Urticaria diagnosis drug therapy etiology Young Adult 2013 1 17 6 0 2013 1 17 6 0 2013 10 18 6 0 ppublish 23321995 10.2340/00015555-1494

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2013 Acta Dermato-Venereologica

18. Interferon-beta injection site reactions in patients with multiple sclerosis. (PubMed)

by potential skin toxicity. Injection site reactions (ISRs), featured by erythema, edema, pain, and pruritus, are the most common adverse reactions. ISRs are mild or moderate in the vast majority of cases, but they can be severe enough to induce drug discontinuation. Therefore, it is very important to adopt strategies to minimize ISRs by proper patient education and counseling. These include rotation of injection sites, use of autoinjectors, use of medication at room temperature, cold compress, or local (...) Interferon-beta injection site reactions in patients with multiple sclerosis. Interferon-beta (IFNβ) is effective treatments for relapsing multiple sclerosis (MS). IFNβ treatment includes subcutaneous (SC) IFNβ-1b, intramuscular (IM) and SC IFNβ-1a, and SC pegylated IFNβ-1a (PEG-IFNβ-1a). PEG-IFNβ-1a offers the advantage of a prolonged duration of action with a less frequent administration (every 2 weeks) and a higher patient adherence. However, the use of SC interferons could be characterized

2018 Journal of Dermatological Treatment

19. Cold medicine-related Stevens–Johnson syndrome/toxic epidermal necrolysis with severe ocular complications–phenotypes and genetic predispositions (PubMed)

Cold medicine-related Stevens–Johnson syndrome/toxic epidermal necrolysis with severe ocular complications–phenotypes and genetic predispositions Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa, such as the ocular surface, oral cavity, and genitals. In patients with extensive skin detachment and a poor prognosis, the condition is called toxic epidermal necrolysis (TEN). Severe ocular complications (SOCs) appear in some-but not all-SJS (...) /TEN patients who are diagnosed by dermatologists, and cold medicines including multi-ingredient cold medications and nonsteroidal anti-inflammatory drugs are the main causative drugs particularly for SJS/TEN with SOCs and all SJS and TEN. In this review, we focus on the genetic predisposition of cold medicine-related SJS/TEN (CM-SJS/TEN) with SOCs. CM-SJS/TEN with SOCs was strongly associated with HLA-A*02:06 and significantly associated with HLA-B*44:03 in Japanese individuals, significantly

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2016 Taiwan journal of ophthalmology

20. Cold Plasma for Wound Treatment, Safety Study

Centres Study Details Study Description Go to Brief Summary: In this study the application of cold atmospheric plasma (CAP) will be tested on intact skin of volunteers. To test safety, several skin parameters will be monitored, the antimicrobial effect will be investigated as well. The investigators expect this treatment to have a good antimicrobial effect with acceptable, transient skin sensations. Condition or disease Intervention/treatment Phase Intact Skin Contaminant Given to Patient Device: Cold (...) Atmospheric Plasma Phase 1 Detailed Description: Control of infection and bacterial colonisation constitutes a continuing challenge in patients with burns. Prevention of microbial contamination and infection is vital for burn wound care as bacterial presence can result in excessive inflammatory reactions, delayed re-epithelialisation, impaired matrix remodelling and bacteraemia. A novel method to decrease the likelihood of infection and to help cure wounds is cold atmospheric plasma (CAP). CAP has been

2016 Clinical Trials

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