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Six Item Cognitive Impairment Test

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101. Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women

, spatial working memory, executive function and processing speed are assessed via a battery of cognitive tests. Mobility testing comprises three walking tests, some under single and dual task paradigms, as well as the five times sit to stand test, a measure of dynamic balance and functional mobility. Volunteers also provide two blood samples, one for fatty acids analysis and the other serum homocysteine levels. Participants also complete health-related quality of life questionnaire, the short form 36 (...) Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Omega-3

2017 Clinical Trials

102. The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study

/treatment Phase Cognitive Impairment Behavioral: Resistance Training Behavioral: Balance and Tone Training Not Applicable Detailed Description: Investigators will conduct a six-month randomized control trial (RCT) exercise intervention. Thirty older adults (aged 60-80) at-risk for diabetes will be randomly assigned into one of two groups: 1) Resistance training, or 2) Balance and Tone training (control). All participants will engage in three one-hour exercise classes per week. Once a month, a neutral (...) assessor will visit the classes to evaluate the quality of the classes for participants. Assessments will be made at baseline, midpoint (three months) and trial completion (six months), and will include cognitive testing, health questionnaires, physical testing, and magnetic resonance imaging (MRI; to assess structural and functional brain changes). Throughout the study, investigators will examine data for trends in successful recruitment strategies and rates of recruitment and adherence to inform

2017 Clinical Trials

103. Non-cardiac Chest Pain: Effect of Cognitive Therapy Administered as Guided Self-help

Information provided by (Responsible Party): Sorlandet Hospital HF Study Details Study Description Go to Brief Summary: This study aims to test an easily implementable web-based cognitive behaviour therapy (CBT) self-help intervention designed for non-cardiac chest pain patients, and compare effectiveness and cost-effectiveness to treatment as usual in an randomized controlled trial (RCT). Condition or disease Intervention/treatment Phase Chest Pain Behavioral: Guided self-help Not Applicable Detailed (...) : 18 Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Non-Cardiac Chest Pain Exclusion Criteria: Language difficulties Unable to perform at least moderate physical activity due to physical constraints Obvious cognitive impairment (e.g mentally retarded, psychotic, dementia or intoxicated) no regular access to a computer/tablet computer with internet connection Contacts and Locations Go to Information from the National

2017 Clinical Trials

104. CARESSES Testing and Evaluation Phases

and reliability have been widely established. The scale items examine burden associated with functional / behavioural impairments and care situations. Each item is scored on a 5-point Likert Scale ranging from "never" to "nearly always present." A total score is obtained with higher scores indicting higher care burden among informal carers. Short form University of California Los Angeles (UCLA) Loneliness Scale (ULS-8) [ Time Frame: 2 sessions, about 8 min each in length ] Loneliness will be measured using (...) CARESSES Testing and Evaluation Phases CARESSES Testing and Evaluation Phases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. CARESSES Testing and Evaluation Phases The safety and scientific validity

2018 Clinical Trials

105. Testing CBT Models and Change Mechanisms for Alcohol Dependent Women

Eligibility Description: Female participants only Accepts Healthy Volunteers: No Criteria Inclusion Criteria: age 18 or older have a current (past year) Diagnostic and Statistical Manual-IV (DSM-IV) alcohol dependence diagnosis used alcohol in the 60 days prior to telephone screening Exclusion Criteria: have psychotic symptoms in the past six months gross cognitive impairment current physiological dependence on any illicit drug Contacts and Locations Go to Information from the National Library of Medicine (...) ): Elizabeth Epstein, Ph.D., Rutgers, The State University of New Jersey Study Details Study Description Go to Brief Summary: The study has 4 specific aims: (1) To modify our existing Individual Female Specific Cognitive Behavioral Therapy (I-FS-CBT) for Alcohol Use Disorder (AUD) approach to treat women with alcohol dependence in a group format, Group Female Specific Cognitive Behavioral Therapy (G-FS-CBT); (2) To test the relative efficacy of I-FS-CBT and G-FS-CBT; (3) To test hypothesized mechanisms

2018 Clinical Trials

106. A Test-Drive Strategy for the Prescription of Prosthetic Feet for People With Leg Amputations

Measures : Two Minute Walk Test [ Time Frame: Administered at baseline and at 2-week follow up for each foot condition. ] Participants are asked to walk for 2 minutes at their fastest possible speed and distance walked is recorded. Prosthetic Limb Users Survey of Mobility (PLUS-M), tailored short-form [ Time Frame: Administered at baseline and at 2-week follow up for each foot condition. ] Standardized self-report item bank. Activities Specific Balance Confidence Scale (ABC) [ Time Frame: Administered (...) are unable to use test feet for any reason (e.g., excessively long residual limb that is not compatible with wearing study prosthetic feet) unable to walk under the minimal necessary study walking conditions in order to complete the study procedures without undo stress currently pregnant (determined via self-report during screening) current surgical, neurological, rheumatologic, or lower limb musculoskeletal problem that significantly impairs ambulation (e.g., current ulcer, terminal illness, lower

2018 Clinical Trials

107. Driving and off-road impairments underlying failure on road testing in Parkinson's disease. (PubMed)

decision of pass/fail. Participants also completed an off-road evaluation assessing demographic features, disease characteristics, motor function, vision, and cognition. The most important driving skills and off-road predictors of the pass/fail outcome were identified using multivariate stepwise regression analyses. Eighty-six (65%) passed and 36 (35%) failed the on-road driving evaluation. Persons who failed performed worse on all on-road items. When adjusted for age and gender, poor performances (...) Driving and off-road impairments underlying failure on road testing in Parkinson's disease. Parkinson's disease (PD) affects driving ability. We aimed to determine the most critical impairments in specific road skills and in clinical characteristics leading to failure on a road test in PD. In this cross-sectional study, certified driving assessment experts evaluated specific driving skills in 104 active, licensed drivers with PD using a standardized, on-road checklist and issued a global

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2013 Movement Disorders

108. Testing if Reductions in Negative Affect Yield Decreased Emotional Eating Symptoms

) Actual Enrollment : 28 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: Testing if Reductions in Negative Affect Yield Decreased Emotional Eating Symptoms: A Cognitive Bias Intervention Actual Study Start Date : March 28, 2017 Actual Primary Completion Date : May 3, 2017 Actual Study Completion Date : May 3, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Cognitive Bias (...) being tested by other researchers utilizing cognitive bias modification paradigms. The relaxation training sessions will be matched to the length of the treatment condition and therefore will last approximately 30 minutes. Outcome Measures Go to Primary Outcome Measures : Change in Emotional Overeating Questionnaire Scores [ Time Frame: Assessed at baseline (time zero), mid-treatment (8 days after baseline), and post-treatment (2 weeks after baseline). ] Emotional eating will be measured using the 6

2017 Clinical Trials

109. Reliability and Physiological Analysis of an Isometric Test of Localized Muscular Fatigue

on the average of the answers to these six questions, in order to obtain an overall sleep problems score Need for Recovery Scale [ Time Frame: Day 7 ] This is an 11 item scale which aims to evaluate work fatigue symptoms, related to a series of emotional, cognitive and behavioral aspects characterized as temporary overload feelings, irritability, social seclusion, lack of energy for new efforts and performance reduction Borg Scale [ Time Frame: Day 7 ] Participants' physical effort perception will also (...) 1 ] This scale is intended to evaluate participants' sleep and tiredness, which consists in six questions about sleep issues in the previous month. Questions are about (1) problems initiating sleep, (2) awakening from sleep, (3) early morning awakening, (4) not feeling adequately rested, (5) experiencing daytime impairment and (6) being dissatisfied with sleep. To each question participants will answer on a zero to seven days a week scale. The quantity of days will be calculated based

2017 Clinical Trials

110. This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year

baseline in everyday functional capacity as measured by Schizophrenia Cognition Rating Scale (SCoRS) total score after 24 and 52 weeks of treatment [ Time Frame: Baseline, Week 24 and Week 52 ] Change from baseline in the BAC App composite T score after 52 weeks of treatment [ Time Frame: Baseline and Week 52 ] Change from baseline in Positive and Negative Syndrome Scale (PANSS) positive items score, negative items score, and total score after 52 weeks of treatment [ Time Frame: Baseline and Week 52 (...) This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year - Full Text View

2017 Clinical Trials

111. Validation, Reliability and Pilot Test of the Personalized Exercise Questionnaire (PEQ)

-Square test. Secondary Outcome Measures : Preferences to exercise [ Time Frame: 3 months ] Using the PEQ, domains two and four, will be used to quantify the frequency of each preference. Results will be presented in a table with column one representing the survey item and column two representing the frequency of the reported outcome. Barriers to exercise [ Time Frame: 3 months ] Using the PEQ, domain six, will be used to quantify the frequency of each barrier. Results will be presented in a table (...) and/or steroid use. The participant is diagnosed with a reading disability or dyslexia The participant has a cognitive impairment of some severity as to adversely affect the validity of the data Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03125590

2017 Clinical Trials

112. Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers

weak or cognitively impaired to participate in the intervention and complete the assessments Per self-report/screening measures, has received cognitive-behavioral therapy since cancer diagnosis As per medical record or self-report, currently being treated for schizophrenia, substance use or dependence, and/or bi-polar disorder Anxiety due solely to a medical procedure as determined by a patient-report item on the screening questionnaire CAREGIVERS: Endorsing active suicidal ideation on the item (...) Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2017 Clinical Trials

113. Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status

), three symptom scales (fatigue, vomiting and pain) and six single item scales (dyspnea, insomnia, constipation, anorexia, diarrhea, and financial difficulties). Health-related quality of life using QLQ-BN20 [ Time Frame: at baseline and every month until 12 months ] The QLQ-BN20 questionnaire includes 20 items covering functional deficits, symptoms, toxic effects of treatment, and uncertainty about the future. Cognitive assessment MMSEs [ Time Frame: at baseline and they were repeated every month (...) months ] Assessment every 2 weeks until 12 months by physical and neurological examinations, complete blood counts and urine strip tests. Toxicity was graded according to the National Cancer Institute Common Toxicity Criteria (NCI CTCAE, version 3.0). Health-related quality of life using QLQ-C30 questionnaire [ Time Frame: at baseline and every month until 12 months ] The QLQ-C30 questionnaire includes 30 questions comprising five functioning scales (physical, role, emotional, cognitive and social

2016 Clinical Trials

114. Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI)

task to test for memory consolidation and a maze test for executive performance. Each item is scored and then the item scores are totaled. Total scores range from 0 (best) to 90 (worst). Higher scores indicate greater cognitive impairment. A negative change from Baseline indicates improvement. Analysis of Covariance (ANCOVA) model was used for analyses that included treatment, pooled centre, and their interaction as factors and Baseline ADAS-cog+ score as a covariate. Secondary Outcome Measures (...) , a delayed recall task to test for memory consolidation and a maze test for executive performance. Each item is scored and then the item scores are totaled. Total scores range from 0 (best) to 90 (worst). Higher scores indicate greater cognitive impairment. A negative change from Baseline indicates improvement. ANCOVA model was used for analyses that included treatment, pooled centre, and their interaction as factors and Baseline ADAS-cog+ score as a covariate. Change From Baseline in Montreal Cognitive

2012 Clinical Trials

115. Effect of Alternating Postures on Cognitive Performance

participants were familiarized with the study protocol. Sitting time and weekly physical activity were determined via the long version of the International Physical Activity Questionnaire (IPAQ, only on the first day of measurement). Examples of each cognitive test implemented in the cognitive phase were executed according to their guidelines. A 30 minute break in a sitting posture was used to ascertain baseline heart-rate level. Baseline heart-rate was calculated after a 20 minute rest for a 5 minute (...) interval. In the second (cognitive) phase subjects participated in a test battery containing five blocks. Each block consisted of a working speed test (text editing task), an attentional test (d2R-test of attention) and a reaction time test (Stroop-test). These tests lasted for 30 minutes to fulfill recommendations regarding postural changes. To simulate "common" working conditions (computer based and non-computer based tasks), digital (text editing task, Stroop-test) as well as pen & paper (d2R-test

2016 Clinical Trials

116. Cognition Metabolism and Exercise Among Women Living With HIV in Puerto Rico

an intervention (described above) designed for normally active but physically untrained HIV+ Hispanic women, one with (n=15) and other without (n=15) neurocognitive impairment & HIV- controls (n=15). After the HIIT intervention, measurements of CR-fitness, insulin resistance, and cognitive function including hippocampal function using the memory island test will be obtained, as well as CR-fitness, anthropometry, DEXA densitometry, and blood and urine samples for metabolic testing. The ultimate goal (...) (n=15) neuro-cognitive impairment (HAND) on antiretroviral therapy (CART) receive 2 weeks, 6 sessions of 8 x 60 seconds cycling bouts eliciting approximately 80% of maximal heart rate with 60 second rest between bouts after which they will receive 4 week, 12 sessions of 10 x 60 seconds cycling bouts eliciting approximately 90% of maximal heart rate with 60 second rest between bouts. Other: High intensity interval training (HIIT) Six weeks, three days per week (total of 18 sessions) of HIIT cycle

2016 Clinical Trials

117. Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis

symptoms in addition to antipsychotic treatment vary between small to medium. However, the effect sizes for changes in delusions are somewhat lower. Thus, it could prove beneficial to tailor CBTp interventions more precisely to the processes that are relevant to delusions. Empirically derived models of the formation and maintenance of delusions postulate an important role of cognitive biases, emotional factors and self-esteem. Additional studies have demonstrated the relevance of impaired sleep (...) that a combination of CBT-interventions within a broader therapy rational might have an even greater impact on delusions. The aim of the present single-blind randomized-controlled therapy study is to assess the efficacy of a new form of Cognitive Behavioral Therapy for delusions with a focus on emotion regulation, improvement of self-esteem and sleep quality (CBTd-E) that will be applied in 25 individual sessions. Moreover, the study aims to test whether the efficacy of CBTd-E is mediated by the postulated

2016 Clinical Trials

118. Development and Validation of a Smart Phone Based System to Enhance Gait, Cognition and Socialization in Elderly Fallers

and 3 months after completing the training ] Working memory (forward and backward digit span): Forward and backward digit span is a common measure of short-term memory (working memory). It is also a component of cognitive ability tests. Backward memory span is a more challenging variation which involves recalling items in reverse order. Changes in cognitive function: number of correct / incorrect answers [ Time Frame: At baseline, immediately after the training and 3 months after completing (...) risk and impaired cognitive function that are so common among older adults, enabling them to live longer successfully and independently. Condition or disease Intervention/treatment Phase Older Adults Device: Monitoring and training using the system Behavioral: Standard of care Not Applicable Detailed Description: A comprehensive system will be developed to promote mobility, enhance cognitive function, reduce sedentary behavior, increase independence and encourage social inclusion. This novel system

2016 Clinical Trials

119. A Superiority Study To Compare The Effects Of An 8-Weeks Mindfulness-based Intervention Versus Health Education Programme On Mental Health And Wellbeing In Individuals With Subjective Cognitive Decline

in the earliest stages for intervention when neurodegeneration is still limited. Individuals clinically judged to have SCD, defined by subjectively experienced cognitive decline but normal performance on cognitive tests, are at increased risk for future cognitive decline and AD. These individuals with SCD currently have no established treatment options. Symptoms of anxiety have high prevalence in this population, and evidence from recent longitudinal research links anxiety with significantly accelerated (...) to affect a number of areas of life we will also look at changes in other areas of psycho-affective symptoms, social functioning, awareness, well being and quality of life, sleep quality, and cognition, after the intervention and 16 weeks after the end of the intervention. Validated neuropsychological tests and behavioural questionnaires were selected for their sensitivity to the domains listed above. These measures will be completed alone by the participant or in the presence of a psychometrist

2016 Clinical Trials

120. The Effectiveness of TECH: Tablet Enhancement of Cognition and Health

Sponsor: Assuta Hospital Systems Information provided by (Responsible Party): Zvi Buckman, Assuta Hospital Systems Study Details Study Description Go to Brief Summary: This study assess the effectiveness of novel cognitive intervention utilizing tablet apps (TECH protocol: Tablet Enhancement of Cognition and Health) to improve cognitive abilities, daily function and health-related quality of life of older adults with MCI. Forty six older adults with MCI will be randomly allocated to the TECH protocol (...) (experimental group) or standard care (control group). Assessments will be administered pre and post the 6-week TECH protocol and at 6-month follow-up by assessors blind to group allocation. Condition or disease Intervention/treatment Phase Mild Cognitive Impairment Other: TECH: Tablet Enhancement of Cognition and Health Not Applicable Detailed Description: A single-blind randomized controlled trial (RCT) will be conducted, by assessors blind to group allocation. Participants will be referred to the study

2016 Clinical Trials

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