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Six Item Cognitive Impairment Test

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41. A Systematic Evidence Review of the Signs and Symptoms of Dementia and Brief Cognitive Tests Available in VA

that was highly specific for AD, however, was impaired sense of touch for perceiving the form of an object (stereognosis), or the form of a letter or number written on the skin (graphesthesia).3 A Systematic Evidence Review of the Signs and Symptoms of Dementia and Brief Cognitive Tests Available in VA Evidence-based Synthesis Program KEY QUESTION #2. Which measures of cognitive function provide the optimal sensitivity, specificity, and time to completion among the measures available to V A providers? All 6 (...) patients with mild cognitive impairment (MCI). The SLUMS test was studied in a V A population and found to have high sensitivity (98-100%) and specificity (98-100%) with adjustment for education. The SLUMS takes longer to administer than other tests. It was developed more recently than the other tests and has not been widely studied. The STMS has been studied in a primary care setting. The STMS had sensitivity ranging from 86% to 95%, and specificity was highest (93.5%) when cut-off score was adjusted

2010 Veterans Affairs Evidence-based Synthesis Program Reports

42. Knee Stability and Movement Coordination Impairments: Knee Ligament Sprain

-Item Short-Form Health Survey TSK-11 Tampa Scale of Kinesiophobia Introduction Aim of the Guidelines The Orthopaedic Section of the American Physical Therapy Association (APTA) has an ongoing effort to create evidence-based clinical practice guidelines (CPGs) for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World Health Organization's International Classification of Functioning, Disability and Health (ICF). The purposes of these clinical (...) , including how directly the studies addressed the question on knee stability and movement coordination impairments/knee ligament sprain population. In developing their recommendations, the authors considered the strengths and limitations of the body of evidence and the health benefits, side effects, and risks of tests and interventions. Guideline Review Process and Validation Identified reviewers who are experts in knee ligament injury management and rehabilitation reviewed the content and methods

2017 American Physical Therapy Association

43. CogStim, a Pilot Study : Cognitive Rehabilitation Management of HIV-1 Mild Cognitively Impaired Patients Controlled With Antiretroviral Therapy

penetration (Annex 15) With cognitive complaint objectified by the cognitive complaint questionnaire (Appendix 9: score 3 or 1 positive response among the items C4, C5, C7, C8) and cognitive impairment found by an alteration of at least two cognitive fields assessed by psychometric tests for at least 6 months 18 55 on the scale of Spielberger STAI-Y (Annex 14) Insured under (...) patients show asymptomatic neurocognitive impairment or minor cognitive disorder. These symptoms impact the compliance of the treatment, though its performance and daily life quality. To this day, no therapy tested has proved its efficiency, including the strategy of the antiretroviral therapy (cART) optimization according to the Cerebral Penetration effectiveness Score (CPE). Description of the study: an open prospective comparative monocentric pilote study, randomised in three groups which

2014 Clinical Trials

44. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

laboratory testing once yearly for low-risk patients and twice yearly for higher-risk patients has been recommended, the same recommendations call for POC screening every six months Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients 11 for low-risk patients and every three months for higher-risk pa- tients(13), which is far more frequent than the previously cit- ed ASIPP recommendations(14, 15). Therefore, due to a lack of scientific evidence to suggest that random (...) Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic

2018 American Academy of Pain Medicine

45. Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism

Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2017 Clinical Trials

46. Cognitive and Mind-Body Therapies for Chronic Low Back and Neck Pain: Effectiveness and Value

Report List of Acronyms Used in this Report AAPM American Academy of Pain Medicine AHRQ Agency for Healthcare Research and Quality ACP American College of Physicians AMSTAR A Measurement Tool to Assess Systematic Reviews APS American Pain Society CBT Cognitive Behavioral Therapy CDC Centers for Disease Control and Prevention CMS Centers for Medicare and Medicaid Services CPGS Chronic Pain Grade Scale FFbHR Functional questionnaire Hannover for everyday diagnosis of functional impairment by back pain (...) of cognitive and mind-body therapies for chronic neck pain. Comparative Clinical Effectiveness We abstracted data on the interventions considered in this review from the AHRQ systematic review of therapies for low back pain and from subsequent randomized trials of the same interventions for patients with chronic low back pain. Evidence on intervention effectiveness focused on studies of at least six months’ duration or studies of more limited duration with outcomes assessed at least four weeks after

2017 California Technology Assessment Forum

47. Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation

from baseline cognitive visual memory at 12 weeks and 6 months [ Time Frame: Baseline, 12 weeks, & 6 month ] The Brief Visuo-Spatial Memory Test (BVMT) will be used to measure visual memory Participants are presented with six abstract designs for 10 seconds, the display is then removed from view and participant are instructed to draw the designs from memory via pencil on paper. Each design is scored from 0 to 2 points representing accuracy and location. There are three learning trials. Test (...) by (Responsible Party): Dr. Anthony Feinstein, Sunnybrook Health Sciences Centre Study Details Study Description Go to Brief Summary: Given that up to 70% of people with secondary progressive MS are cognitively impaired, the search for effective treatments is considered a priority by people living with the disease. This proposal will address the effectiveness of cognitive rehabilitation (CR) and exercise, either alone, or in combination in this regard. A team of MS researchers has been assembled from the USA

2018 Clinical Trials

48. An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction

,contain 23 items of the core symptoms of cognitive impairment. And the scale is used to measure the changes of symptoms of Chinese medicine before and after treatment. Other Outcome Measures: whole blood cell test [ Time Frame: 90 days ] blood routine test routine urine test [ Time Frame: 90 days ] routine urine test Liver function [ Time Frame: 90 days ] test the blood to detect the liver function,such as alanine aminotransferase(ALT) ,aspartate aminotransferase(AST),total bilirubin (TBIL), γ (...) An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2016 Clinical Trials

49. Adderall XR and Cognitive Impairment in MS

of the most commonly used tests to assess processing speed in the MS population and is included in the two validated neuropsychological test batteries routinely used in MS studies, the Minimal Assessment of Cognitive Function in MS (MACFIMS). Secondary Outcome Measures : Brief Visuospatial Memory Test Revised - immediate recall [ Time Frame: 12 weeks ] A measure of visual/spatial memory with 3 recall trials of the same six figures, marked for accuracy of the figure drawn and their spatial location (...) ] Is a 15 item self-report questionnaire designed to screen for cognitive impairment (CI) in MS subjects. The questions all relate to cognitive problems in daily life and are scored from 0 (never, does not occur) to 4 (very often, very disruptive) and a composite score is calculated, thus higher numbers indicate greater perceived CI. Assessed at baseline and after taking the study medication for 12 weeks. Perceived Deficits Questionnaire [ Time Frame: 12 weeks ] developed specifically for the MS

2016 Clinical Trials

50. An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors

An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02515487 Recruitment Status : Completed First Posted : August 4, 2015 Last Update Posted : February 6, 2018 Sponsor: New York University

2015 Clinical Trials

51. Galantamine and Memantine for Cognitive Impairments in Schizophrenia

. This is an open-label study to evaluate whether a six week course of galantamine ER and memantine XR is effective in improving the cognitive performance of patients with schizophrenia or schizoaffective disorder. The primary outcome measure will be the change in level of cognition as measured by the MATRICS Consensus Cognitive Battery (MCCB). The results of the MATRICS collaborative project recommended the need for standardized cognitive tests that better distinguish the different facets of cognitive (...) Galantamine and Memantine for Cognitive Impairments in Schizophrenia Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2014 Clinical Trials

52. Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease

of 85 points (0: no cognitive impairment; 85: severe impairment). Change in functional performance as measured by the Clinical Dementia Rating (CDR) Scale [ Time Frame: Baseline, 3 months, 6 months ] The CDR is a 5-point scale used to characterize six domains of cognitive and functional performance applicable to Alzheimer disease and related dementias: Memory, Orientation, Judgment & Problem Solving, Community Affairs, Home & Hobbies, and Personal Care. Scores on the CDR range from 0 (no impairment (...) ) to 3 (severe impairment). The total CDR ratings for each of the six cognitive/functional domains can be added to create a CDR sum of boxes (SOB). Change in functional performance as measured by the Functional Activities Questionnaire (FAQ) [ Time Frame: Baseline, 3 months, 6 months ] The FAQ measures instrumental activities of daily living (IADLs), such as preparing balanced meals and managing personal finances. The FAQ is a sum of scores ranging from 0 (normal) to 30 (complete dependence on others

2015 Clinical Trials

53. Properties of a brief assessment tool for longitudinal measurement of cognition in people living with HIV. (PubMed)

. The objective of this study is to estimate the extent of change on repeat administration of three different forms of a brief computerized cognitive assessment battery (B-CAM) developed for assessing cognitive ability in the mildly-impaired to normal range in people living with HIV. We hypothesized no change over a six-month period in people on effective antiretroviral therapy.102 HIV+ individuals completed a set of computerized cognitive tasks on three occasions over a six-month period. Rasch analysis (...) sessions, related to the different forms of the tasks. These two items were split by testing session. For all other items, the level of difficulty remained constant across all three time points. GBTA showed that the sample was composed of three distinct groups of people with unique trajectories, defined mainly by level of cognitive ability at baseline. Only the highest group showed an apparent improvement over time, but this change fell within measurement error.Rasch analysis provides mathematical

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2019 PLoS ONE

54. Evaluating cognitive screening instruments with the "likelihood to be diagnosed or misdiagnosed" measure

diagnostic test accuracy studies examining four commonly used cognitive screening instruments (Mini-Mental State Examination, MMSE; Montreal Cognitive Assessment, MoCA; Mini-Addenbrooke's Cognitive Examination, MACE; Six-item Cognitive Impairment Test, 6CIT) were analysed to calculate NND, NNP, and NNM, and from these derive values for LDM.Although all the tests had low NND and NNP as desired, NNM was also low. Hence, only MMSE and 6CIT achieved LDM > 1 for dementia diagnosis, and only MACE and 6CIT had (...) Evaluating cognitive screening instruments with the "likelihood to be diagnosed or misdiagnosed" measure To calculate "number needed to diagnose" (NND), "number needed to predict" (NNP), and "number needed to misdiagnose" (NNM) for cognitive screening instruments which are commonly used in suspected dementia and mild cognitive impairment, and from these to calculate a "likelihood to be diagnosed or misdiagnosed" (LDM) metric as the ratio of NNM to either NND or NNP.Datasets from pragmatic

2018 EvidenceUpdates

55. Effects and Mechanism of Two Hybrid Exercise-cognitive Trainings in Mild Ischemic Stroke With Cognitive Decline

. In particular, we will be analyzing the total antioxidant capacity (TAC). Glucose indicator [ Time Frame: Baseline, posttest (an expected average of 3 months) ] HbA1C level will be tested to investigate the relationships between blood glucose level and aerobic exercise Plasma lipid level [ Time Frame: Baseline, posttest (an expected average of 3 months) ] The cholesterol ratio (total cholesterol divided by high-density lipid) will be evaluated to reflect the lipid level in the blood Montreal Cognitive (...) functions Wechsler Adult Intelligence Scale - Third Edition (WAIS-III) [ Time Frame: Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) ] The WAIS-III is developed to measure an individual's intelligence level. It includes tests that evaluate cognitive functions in verbal comprehension, working memory, perceptual organization, and processing speed Useful Field of View (UFOV) [ Time Frame: Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months

2017 Clinical Trials

56. Knee Pain and Mobility Impairments: Meniscal and Articular Cartilage Lesions

or ?eld tests, such as single-legged hop tests (eg, single hop for distance, cross- over hop for distance, triple hop for distance, and 6-m timed hop), that can identify a patient’s baseline status relative to pain, function, and dis- ability; detect side-to-side asymmetries; assess global knee function; de- termine a patient’s readiness to return to activities; and monitor changes in the patient’s status throughout the course of treatment. EXAMINATION – PHYSICAL IMPAIRMENT MEASURES 2018 (...) Recommendation B Clinicians should administer appropriate physical impair- ment assessments of body structure and function, at least at baseline and at discharge or 1 other follow-up point, for all patients with meniscus tears to support standardization for quality improve- ment in clinical care and research, including the modi?ed stroke test for effusion assessment, assessment of knee active range of motion, maximum voluntary isometric or isokinetic quadriceps strength test- ing, forced hyperextension

2018 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

57. Robot-assisted therapy for long-term upper limb impairment after stroke

. Nearly all patients are disabled immediately following a stroke event. Common disabilities include permanent paralysis of one side of the body, speech or swallowing difficulties, problems with memory, personality changes or a range of other difficulties. Depression, anxiety and cognitive impairment are also common after stroke. By the end of the first year, about half of all survivors of stroke remain dependent on others for activities of daily living. Stroke mainly affects older people (...) paralysis restricted to one side of the body 6 Robot-assisted therapy for upper limb impairment after stroke: November 2010 on patients in the acute and subacute phase of their stroke (= 3 months) and those in the chronic phase (>3 months duration). The primary and secondary outcomes of the included studies were an improvement in daily living activity and changes in arm motor function impairment, respectively. The methodological quality of the included studies was assessed using the PEDro scale. 5 Six

2011 Australia and New Zealand Horizon Scanning Network

58. Blood Pressure and Cognitive Decline Over 8 Years in Middle-Aged and Older Black and White Americans. (PubMed)

and followed through September 2015, we measured changes in cognition associated with baseline systolic and diastolic BP (SBP and DBP), as well as pulse pressure (PP) and mean arterial pressure, and we tested whether age, race, and sex modified the effects. Outcomes were global cognition (Six-Item Screener; primary outcome), new learning (Word List Learning), verbal memory (Word List Delayed Recall), and executive function (Animal Fluency Test). Median follow-up was 8.1 years. Significantly faster declines (...) Blood Pressure and Cognitive Decline Over 8 Years in Middle-Aged and Older Black and White Americans. Although the association between high blood pressure (BP), particularly in midlife, and late-life dementia is known, less is known about variations by race and sex. In a prospective national study of 22 164 blacks and whites ≥45 years without baseline cognitive impairment or stroke from the REGARDS cohort study (Reasons for Geographic and Racial Differences in Stroke), enrolled 2003 to 2007

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2019 Hypertension

59. Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia. (PubMed)

Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia. With the long-term goal of improving community health by screening for dementia, we tested the utility of integrating the Six-Item Screener (SIS) into our emergency department neurology consultations.In this cross-sectional observational study, we measured SIS performance within 24 hours of hospital arrival in 100 consecutive English-speaking patients aged ≥45 years (...) . Performance was compared to patient age, previously charted cognitive impairment, and proxies for in-hospital complexity: whether or not a patient was admitted to the hospital and the number of medical studies ordered.Those with poor SIS performance were older (p = 0.02) and more likely to have previously charted cognitive impairment (p < 0.01; sensitivity 86%, specificity 77%). Poor performers were more likely to be admitted to the hospital (p = 0.04; odds ratio 3.6) and were subjected to more tests once

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2019 Neurology

60. Study protocol: associations between dietary patterns, cognitive function and metabolic syndrome in older adults - a cross-sectional study. (PubMed)

and Cognitive Health) study is to investigate associations between dietary patterns, cognitive function and metabolic syndrome, accounting for a range of covariates.This cross-sectional study design will recruit older, community-living adults (65-74 years) from Auckland, New Zealand. Dietary data will be collected via a 109-item food frequency questionnaire validated using a 4-day food record. Cognitive function will be assessed using the Montreal Cognitive Assessment (paper based) and the Computerised (...) Mental Performance Assessment System (COMPASS) - a testing suite covering six domains. Additional data will include genetic (Apolipoprotein E ε4) and biochemical markers (fasting glucose, HbA1c, lipids profile), anthropometric measurements (weight, height, waist and hip circumference, body composition using dual X-ray absorptiometry), blood pressure, physical activity (International Physical Activity Questionnaire - short form) and health and demographics (questionnaire). Dietary patterns

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2019 BMC Public Health

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