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Six Item Cognitive Impairment Test

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21. Efficacy Study of Yi-Zhi-An-Shen Granules For Older Adults With Amnestic Mild Cognitive Impairment

: Baseline, 8 weeks, 16 weeks, 10 months, 16 months, 22 months ] Changes in the global cognitive function will be accessed by MMSE to evaluate the severity of subjects' cognitive impairment. The MMSE includes orientation, registration, attention and calculation, recalling and language tests, for a total of 30 points. A score below 24 is considered abnormal for dementia screening. Change from Baseline in the Montreal Cognitive Assessment (MoCA) [ Time Frame: Baseline, 8 weeks, 16 weeks, 10 months, 16 (...) and related dementias: Memory, Orientation, Judgment and Problem Solving, Community Affairs, Home and Hobbies, and Personal Care. Scores on the CDR range from 0 (no impairment) to 3 (severe impairment). The total CDR ratings for each of the six cognitive/functional domains can be added to create a CDR sum of boxes (CDR-SB). Change from Baseline in the Activity of Daily Living (ADL) [ Time Frame: Baseline, 8 weeks, 16 weeks, 10 months, 16 months, 22 months ] ADLs will be assessed including basic activities

2018 Clinical Trials

22. VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment

with balance control and falls. Further, the effect of VR-based training on balance control and cognitive function is unknown among the older adults with mild cognitive impairment. Therefore, to address the cognitive domains explicitly, the current study aims to test the applicability of Wii-Fit Nintendo along with an additional cognitive load delivered via VR-based cognitive-motor training paradigm (VR-CogMoBal) in older adults with mild cognitive impairment. Lastly, the study also aims to identify (...) VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

23. Episodix: a serious game to detect cognitive impairment in senior adults. A psychometric study Full Text available with Trip Pro

study to assess cognitive impairment.After a preliminary study, a new pilot study, statistically significant for the Galician population, was carried out from a cross-sectional sample of senior adults as target users. A total of 64 individuals (28 HC, 16 MCI, 20 AD) completed the experiment from an initial sample of 74. Participants were administered a collection of classical pen-and-paper tests and interacted with the games developed. A total of six machine learning classification techniques were (...) Episodix: a serious game to detect cognitive impairment in senior adults. A psychometric study Assessment of episodic memory is traditionally used to evaluate potential cognitive impairments in senior adults. The present article discusses the capabilities of Episodix, a game to assess the aforementioned cognitive area, as a valid tool to discriminate among mild cognitive impairment (MCI), Alzheimer's disease (AD) and healthy individuals (HC); that is, it studies the game's psychometric validity

2018 PeerJ

24. The Six-Item Screener and AD8 for the Detection of Cognitive Impairment in Geriatric Emergency Department Patients Full Text available with Trip Pro

The Six-Item Screener and AD8 for the Detection of Cognitive Impairment in Geriatric Emergency Department Patients We evaluate the diagnostic test characteristics of the Six-Item Screener and the AD8 to detect cognitive dysfunction in adults older than 65 years and using the emergency department (ED) for any reason.We conducted an observational cross-sectional cohort study at a single academic urban university-affiliated hospital. Subjects were consenting, non--critically ill, English-speaking (...) adults older than 65 years and receiving care in the ED. We quantitatively assessed the diagnostic test characteristics of the Six-Item Screener and AD8 by using the Mini-Mental State Examination score less than 24 as the criterion standard for cognitive dysfunction.The prevalence of cognitive dysfunction was 35%, but only 6% of charts noted a pre-existing deficit. The Six-Item Screener was superior to either the caregiver-administered AD8 or the patient-administered AD8 for the detection

2011 EvidenceUpdates

25. Appropriate prescribing of psychotropic medication for non-cognitive symptoms in people with dementia

Evidence for antidepressants 105 A3.5 Summary of NICE recommendations (cognitive impairment) 106 Appendix 4 A4.1 List of those invited to provide feedback 107 A4.2 Feedback received and resulting action 108 Appendix 5a A5.a.1 PICOS for economic search 122 A5.a.2 Inclusion and exclusion criteria 123 A5.a.3 BMJ checklist 125 A5.a.4 Consensus on health economic criteria 126 A5.a.5 Extraction summary 129 A5.a.6 Analysis and result detail 130 Appendix 5b A5.b.1.1 Direct implementation cost 136 A5.b.2.1 (...) Grading of Recommendations Assessment, Development and Evaluation GDG Guideline Development Group GDP Global Domestic Product MCI Mild Cognitive Impairment MHBC Ministry of Health British Columbia MHRA Medicines and Healthcare products Regulatory Agency NCEC National Clinical Effectiveness Committee NHMRC National Health and Medical Research Council NHS National Health Service NICE National Institute for Health and Care Excellence NPI Neuropsychiatric Inventory PBS Pharmaceutical Benefit Scheme PDD

2019 National Clinical Guidelines (Ireland)

26. Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning

Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning Key Points • Regular use refers to weekly or more frequent cannabis use over a period of months to years. Regular cannabis use is associated with mild cognitive difficulties, which are typically not apparent following about one month of abstinence. Heavy (daily) and long-term cannabis use is related to more noticeable cognitive impairment. • Cannabis use beginning prior to the age of 16 or 17 is one of the strongest (...) predictors of cognitive impairment. However, it is unclear which comes first — whether cognitive impairment leads to early onset cannabis use or whether beginning cannabis use early in life causes a progressive decline in cognitive abilities. • Regular cannabis use is associated with altered brain structure and function. Once again, it is currently unclear whether chronic cannabis exposure directly leads to brain changes or whether differences in brain structure precede the onset of chronic cannabis use

2019 Canadian Centre on Substance Abuse

27. Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning

Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning Key Points • Regular use refers to weekly or more frequent cannabis use over a period of months to years. Regular cannabis use is associated with mild cognitive difficulties, which are typically not apparent following about one month of abstinence. Heavy (daily) and long-term cannabis use is related to more noticeable cognitive impairment. • Cannabis use beginning prior to the age of 16 or 17 is one of the strongest (...) predictors of cognitive impairment. However, it is unclear which comes first — whether cognitive impairment leads to early onset cannabis use or whether beginning cannabis use early in life causes a progressive decline in cognitive abilities. • Regular cannabis use is associated with altered brain structure and function. Once again, it is currently unclear whether chronic cannabis exposure directly leads to brain changes or whether differences in brain structure precede the onset of chronic cannabis use

2019 Canadian Centre on Substance Abuse

28. Can an observational pain assessment tool improve time to analgesia for cognitively impaired older persons? A cluster randomised controlled trial. Full Text available with Trip Pro

bone fracture were screened for cognitive impairment using the Six-Item Screening (SIS) tool. Patients scoring 4 or less on SIS (intervention sites) were assessed for pain using PAINAD. Control sites, assessed pain using standard methods. The primary outcome was time to first dose of analgesia and was analysed on an intention-to-treat basis with a sensitivity analysis.We enrolled 602 patients, of which 323 (54%) were at intervention sites (n=4). The median time to analgesia was 82 min (IQR 45-151 (...) Can an observational pain assessment tool improve time to analgesia for cognitively impaired older persons? A cluster randomised controlled trial. The primary objective of the study was to measure the impact of an observational pain assessment dementia tool on time from ED arrival to first dose of analgesic medicine.A multisite cluster randomised controlled trial was conducted to test the Pain Assessment in Advanced Dementia (PAINAD) tool. Patients aged 65 years or older suspected of a long

2017 Emergency Medicine Journal Controlled trial quality: predicted high

29. Initial development of a patient-reported outcome measure of experience with cognitive impairment associated with schizophrenia Full Text available with Trip Pro

participants. Cognitive debriefing interviews (n=22) resulted in the removal of 18 items and modification of 22 other items. The remaining 35 items represented 23 concepts within six domains plus two items assessing bother. The draft PRO measure is currently undergoing psychometric testing as a precursor to broad-based clinical and research use. (...) Initial development of a patient-reported outcome measure of experience with cognitive impairment associated with schizophrenia Cognitive impairment is a serious, often distressing aspect of schizophrenia that affects patients' day-to-day lives. Although several interview-based instruments exist to assess cognitive functioning, a reliable measure developed based on the experiences of patients facing cognitive difficulties is needed to complement the objective performance-based assessments

2017 Patient related outcome measures

30. CBT for African Americans With Cognitive Impairment

Association Information provided by (Responsible Party): Ambar Kulshreshtha, Emory University Study Details Study Description Go to Brief Summary: The aim of the study is to test the feasibility and acceptability of a six-month cognitive-behavioral therapy (CBT) program (group based and phone-based) compared with usual care, and to determine if the intervention can improve cognitive performance and reduce chronic stress in a randomized trial including 60 African American patients with Mild Cognitive (...) , improper diet and physical inactivity. Cognitive-behavioral therapy (CBT) is a collaborative psychological approach that addresses the interaction between people's thoughts, feelings and behavior. Existing evidence suggests that CBT can be an effective strategy for dementia patients with co-morbid anxiety. However, none of these studies have specifically evaluated African Americans with MCI. The aim of the study is to test the feasibility and acceptability of a six-month CBT program (group based

2017 Clinical Trials

31. Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment

not to be prone to participating in conventional exercise programs and might have a positive effect on their cognitive function. In spite of this, scientific evidence regarding the effects of BG on people with cognitive impairment is scarce. Behavioral: Brain Gym Exercises Participants in the BrainGym Exercises group performed six of the following BG exercises in every training session they took part in: "Cross Crawl", "Gravity Glider", "Arm Activation", "Belly Breathing", "Hook-ups", "Think of an X", "Lazy (...) Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2017 Clinical Trials

32. Conceptual review of measuring functional impairment: findings from the Weiss Functional Impairment Rating Scale Full Text available with Trip Pro

are found with ADHD specific measures. The Impairment Rating Scale includes questions pertaining to peers, family, academics and self-esteem, but each domain is represented by a single item and the scale loads as a single factor. The ADHD-FX scale examines school, home and peer functioning, but is not specific to functional impairment and does not include a designated time frame. The Barkley Functional Impairment Scale (BFIS) for children and adults assesses impairment over the past 6 months (...) the research and the clinical populations in which it will be used. Psychometric validation must include empirical definitions of improvement as well as cut-offs from normal populations. A measure should include comparable versions appropriate to self, parent and collateral informants. To assure appropriate usage in varying cultures, a measure of functional impairment needs to include a breadth of potential items, while being scored in such a way as to only rate those items that are relevant

2018 Evidence-Based Mental Health

33. MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes

MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record (...) Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal

2015 Clinical Trials

34. Mindfulness?based interventions for improving cognition, academic achievement, behavior, and socioemotional functioning of primary and secondary school students Full Text available with Trip Pro

[CI 0.148, 0.305] and heterogeneity was not significant. Of the 12 moderators tested, only one moderator was significant—studies using clinical samples reported significantly larger effect sizes than studies using non‐clinical samples. Additional analyses performed found significantly greater effects for psychological symptoms than measures of other outcomes. conducted a systematic review and meta‐analysis of MBis in schools with a focus on psychological outcomes (cognitive performance, emotional (...) were excluded from this review. 3.1.4 Types of outcome measures Studies must have reported at least one of the following outcomes: 1. Cognition (e.g., executive function, memory, cognition, attention) 2. Academic performance (e.g., standardized achievement tests, measures of content mastery, reading, grades) 3. Behavior (e.g., disciplinary referrals, aggression and other externalizing behaviors, time on task, compliance, attendance) 4. Socioemotional (e.g., anxiety, stress, engagement, social

2017 Campbell Collaboration

35. Optimizing the G8 Screening Tool for Older Patients With Cancer: Diagnostic Performance and Validation of a Six-Item Version Full Text available with Trip Pro

an optimized version of the G8.We used a prospective cohort of cancer patients aged ≥ 70 years referred to geriatricians for GA (2007-2012: n = 729 [training set]; 2012-2014: n = 414 [validation set]). Abnormal GA was defined as at least one impaired domain across seven validated tests. Multiple correspondence analysis, multivariate logistic regression, and bootstrapped internal validation were performed sequentially.The final model included six independent predictors for abnormal GA: weight loss (...) Optimizing the G8 Screening Tool for Older Patients With Cancer: Diagnostic Performance and Validation of a Six-Item Version A multidimensional geriatric assessment (GA) is recommended in older cancer patients to inventory health problems and tailor treatment decisions accordingly but requires considerable time and human resources. The G8 is among the most sensitive screening tools for selecting patients warranting a full GA but has limited specificity. We sought to develop and validate

2016 The oncologist

36. Cognitive and Mind-Body Therapies for Chronic Low Back and Neck Pain: Effectiveness and Value

Report List of Acronyms Used in this Report AAPM American Academy of Pain Medicine AHRQ Agency for Healthcare Research and Quality ACP American College of Physicians AMSTAR A Measurement Tool to Assess Systematic Reviews APS American Pain Society CBT Cognitive Behavioral Therapy CDC Centers for Disease Control and Prevention CMS Centers for Medicare and Medicaid Services CPGS Chronic Pain Grade Scale FFbHR Functional questionnaire Hannover for everyday diagnosis of functional impairment by back pain (...) of cognitive and mind-body therapies for chronic neck pain. Comparative Clinical Effectiveness We abstracted data on the interventions considered in this review from the AHRQ systematic review of therapies for low back pain and from subsequent randomized trials of the same interventions for patients with chronic low back pain. Evidence on intervention effectiveness focused on studies of at least six months’ duration or studies of more limited duration with outcomes assessed at least four weeks after

2017 California Technology Assessment Forum

37. Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation

from baseline cognitive visual memory at 12 weeks and 6 months [ Time Frame: Baseline, 12 weeks, & 6 month ] The Brief Visuo-Spatial Memory Test (BVMT) will be used to measure visual memory Participants are presented with six abstract designs for 10 seconds, the display is then removed from view and participant are instructed to draw the designs from memory via pencil on paper. Each design is scored from 0 to 2 points representing accuracy and location. There are three learning trials. Test (...) by (Responsible Party): Dr. Anthony Feinstein, Sunnybrook Health Sciences Centre Study Details Study Description Go to Brief Summary: Given that up to 70% of people with secondary progressive MS are cognitively impaired, the search for effective treatments is considered a priority by people living with the disease. This proposal will address the effectiveness of cognitive rehabilitation (CR) and exercise, either alone, or in combination in this regard. A team of MS researchers has been assembled from the USA

2018 Clinical Trials

38. Single screening questions for cognitive impairment in older people: a systematic review Full Text available with Trip Pro

Single screening questions for cognitive impairment in older people: a systematic review Single-item screening questions may be a practical first step in screening for cognitive problems in older people. A form of single-item cognitive assessment is proposed in the NHS England and Wales dementia strategy. We aimed to provide a review and synthesis of the evidence regarding the performance of single-item tests for detection of cognitive impairment.This review used Cochrane diagnostic test (...) accuracy procedures. Two independent researchers searched for relevant papers across multiple, cross-disciplinary electronic databases using previously validated search strings. Our index test was any single screening question for cognitive impairment, including factor analysis of multi-item tools. Our reference standards included clinical diagnosis and multi-domain cognitive assessments.From 884 titles, 11 studies were identified as eligible for inclusion. Four studies were graded low risk of bias

2014 EvidenceUpdates

39. Properties of a brief assessment tool for longitudinal measurement of cognition in people living with HIV. Full Text available with Trip Pro

. The objective of this study is to estimate the extent of change on repeat administration of three different forms of a brief computerized cognitive assessment battery (B-CAM) developed for assessing cognitive ability in the mildly-impaired to normal range in people living with HIV. We hypothesized no change over a six-month period in people on effective antiretroviral therapy.102 HIV+ individuals completed a set of computerized cognitive tasks on three occasions over a six-month period. Rasch analysis (...) sessions, related to the different forms of the tasks. These two items were split by testing session. For all other items, the level of difficulty remained constant across all three time points. GBTA showed that the sample was composed of three distinct groups of people with unique trajectories, defined mainly by level of cognitive ability at baseline. Only the highest group showed an apparent improvement over time, but this change fell within measurement error.Rasch analysis provides mathematical

2019 PLoS ONE

40. Evaluating cognitive screening instruments with the "likelihood to be diagnosed or misdiagnosed" measure (Abstract)

diagnostic test accuracy studies examining four commonly used cognitive screening instruments (Mini-Mental State Examination, MMSE; Montreal Cognitive Assessment, MoCA; Mini-Addenbrooke's Cognitive Examination, MACE; Six-item Cognitive Impairment Test, 6CIT) were analysed to calculate NND, NNP, and NNM, and from these derive values for LDM.Although all the tests had low NND and NNP as desired, NNM was also low. Hence, only MMSE and 6CIT achieved LDM > 1 for dementia diagnosis, and only MACE and 6CIT had (...) Evaluating cognitive screening instruments with the "likelihood to be diagnosed or misdiagnosed" measure To calculate "number needed to diagnose" (NND), "number needed to predict" (NNP), and "number needed to misdiagnose" (NNM) for cognitive screening instruments which are commonly used in suspected dementia and mild cognitive impairment, and from these to calculate a "likelihood to be diagnosed or misdiagnosed" (LDM) metric as the ratio of NNM to either NND or NNP.Datasets from pragmatic

2018 EvidenceUpdates

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