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Six Item Cognitive Impairment Test

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21. A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication

, working memory, verbal learning, speed of processing, attention/vigilance, visual learning, social cognition, reasoning and problem solving). The MCCB neurocognitive composite score is a standardized mean of the six domain scores (excluding social cognition). Raw scores are converted to age and sex adjusted t-scores which are standardized to normative data, and have a mean of 50 and standard deviation of 10 in the general healthy population. A higher score indicates less impairment. Safety (...) A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information

2018 Clinical Trials

22. A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov

2018 Clinical Trials

23. Rates of Screening for Breast, Colorectal, and Cervical Cancers in Older People With Cognitive Impairment or Dementia: A Meta-Analysis (PubMed)

, 0.91], p = .0007, six studies, N = 18,562). The rates of screening for cervical cancer by Pap smear (pooled OR = 0.88, 95% CI = [0.71, 1.08], p = 0.22, five studies, N = 409,131) and colorectal cancer by fecal occult blood test (pooled OR = 0.87, 95% CI = [0.55, 1.38], p = .55, two studies, N = 2,718) were not significantly lower in people with cognitive impairment or dementia. Conclusion: These historical rates provide a baseline for discussions around the need for more specific guidance to assist (...) , and cervical cancers in patients with and without cognitive impairment or dementia. Studies were summarized quantitatively (random effects meta-analysis), according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Studies reported data 1989-2008. The rate of screening for breast cancer by mammography was lower in women with cognitive impairment or dementia compared with those without (pooled odds ratio [OR] = 0.81, 95% confidence interval [CI] = [0.71

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2018 Gerontology and geriatric medicine

24. Episodix: a serious game to detect cognitive impairment in senior adults. A psychometric study (PubMed)

study to assess cognitive impairment.After a preliminary study, a new pilot study, statistically significant for the Galician population, was carried out from a cross-sectional sample of senior adults as target users. A total of 64 individuals (28 HC, 16 MCI, 20 AD) completed the experiment from an initial sample of 74. Participants were administered a collection of classical pen-and-paper tests and interacted with the games developed. A total of six machine learning classification techniques were (...) Episodix: a serious game to detect cognitive impairment in senior adults. A psychometric study Assessment of episodic memory is traditionally used to evaluate potential cognitive impairments in senior adults. The present article discusses the capabilities of Episodix, a game to assess the aforementioned cognitive area, as a valid tool to discriminate among mild cognitive impairment (MCI), Alzheimer's disease (AD) and healthy individuals (HC); that is, it studies the game's psychometric validity

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2018 PeerJ

25. VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment

with balance control and falls. Further, the effect of VR-based training on balance control and cognitive function is unknown among the older adults with mild cognitive impairment. Therefore, to address the cognitive domains explicitly, the current study aims to test the applicability of Wii-Fit Nintendo along with an additional cognitive load delivered via VR-based cognitive-motor training paradigm (VR-CogMoBal) in older adults with mild cognitive impairment. Lastly, the study also aims to identify (...) VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

26. Can an observational pain assessment tool improve time to analgesia for cognitively impaired older persons? A cluster randomised controlled trial. (PubMed)

bone fracture were screened for cognitive impairment using the Six-Item Screening (SIS) tool. Patients scoring 4 or less on SIS (intervention sites) were assessed for pain using PAINAD. Control sites, assessed pain using standard methods. The primary outcome was time to first dose of analgesia and was analysed on an intention-to-treat basis with a sensitivity analysis.We enrolled 602 patients, of which 323 (54%) were at intervention sites (n=4). The median time to analgesia was 82 min (IQR 45-151 (...) Can an observational pain assessment tool improve time to analgesia for cognitively impaired older persons? A cluster randomised controlled trial. The primary objective of the study was to measure the impact of an observational pain assessment dementia tool on time from ED arrival to first dose of analgesic medicine.A multisite cluster randomised controlled trial was conducted to test the Pain Assessment in Advanced Dementia (PAINAD) tool. Patients aged 65 years or older suspected of a long

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2017 Emergency Medicine Journal

27. CBT for African Americans With Cognitive Impairment

Association Information provided by (Responsible Party): Ambar Kulshreshtha, Emory University Study Details Study Description Go to Brief Summary: The aim of the study is to test the feasibility and acceptability of a six-month cognitive-behavioral therapy (CBT) program (group based and phone-based) compared with usual care, and to determine if the intervention can improve cognitive performance and reduce chronic stress in a randomized trial including 60 African American patients with Mild Cognitive (...) , improper diet and physical inactivity. Cognitive-behavioral therapy (CBT) is a collaborative psychological approach that addresses the interaction between people's thoughts, feelings and behavior. Existing evidence suggests that CBT can be an effective strategy for dementia patients with co-morbid anxiety. However, none of these studies have specifically evaluated African Americans with MCI. The aim of the study is to test the feasibility and acceptability of a six-month CBT program (group based

2017 Clinical Trials

28. Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment

not to be prone to participating in conventional exercise programs and might have a positive effect on their cognitive function. In spite of this, scientific evidence regarding the effects of BG on people with cognitive impairment is scarce. Behavioral: Brain Gym Exercises Participants in the BrainGym Exercises group performed six of the following BG exercises in every training session they took part in: "Cross Crawl", "Gravity Glider", "Arm Activation", "Belly Breathing", "Hook-ups", "Think of an X", "Lazy (...) Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2017 Clinical Trials

29. Initial development of a patient-reported outcome measure of experience with cognitive impairment associated with schizophrenia (PubMed)

participants. Cognitive debriefing interviews (n=22) resulted in the removal of 18 items and modification of 22 other items. The remaining 35 items represented 23 concepts within six domains plus two items assessing bother. The draft PRO measure is currently undergoing psychometric testing as a precursor to broad-based clinical and research use. (...) Initial development of a patient-reported outcome measure of experience with cognitive impairment associated with schizophrenia Cognitive impairment is a serious, often distressing aspect of schizophrenia that affects patients' day-to-day lives. Although several interview-based instruments exist to assess cognitive functioning, a reliable measure developed based on the experiences of patients facing cognitive difficulties is needed to complement the objective performance-based assessments

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2017 Patient related outcome measures

30. MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes

MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record (...) Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal

2015 Clinical Trials

31. Cognitive-behavioural treatment for amphetamine-type stimulants (ATS)-use disorders

a series of mental and physical symptoms such as dizziness, mood or mental changes, chronic tiredness or weakness, physiological and behavioural disorders, flushed or pale skin, malnutrition, ulcers, repetitive motor activity, loss of co‐ordination and physical collapse, anxiety, confusion, insomnia, mood disturbances, cognitive impairments, paranoia, cardiac arrhythmias, toxic psychosis, amphetamine‐induced psychosis, convulsions, coma and death (Baylen & Rosenberg, ; Greene et al., ; Montoya et al (...) of personnel delivering the intervention and participants is not feasible. It is not desirable to blind participants to the knowledge of which condition they are in. Knowledge that you are participating in a cognitive‐behavioural programme is part of the intervention (this knowledge is often categorised along with other non‐specific intervention factors). For this reason, we did not assess the risk of bias of this item. Detection bias: Martin 2010 used an independent researcher to collect outcome measures

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2019 Campbell Collaboration

32. Adderall XR and Cognitive Impairment in MS

of the most commonly used tests to assess processing speed in the MS population and is included in the two validated neuropsychological test batteries routinely used in MS studies, the Minimal Assessment of Cognitive Function in MS (MACFIMS). Secondary Outcome Measures : Brief Visuospatial Memory Test Revised - immediate recall [ Time Frame: 12 weeks ] A measure of visual/spatial memory with 3 recall trials of the same six figures, marked for accuracy of the figure drawn and their spatial location (...) ] Is a 15 item self-report questionnaire designed to screen for cognitive impairment (CI) in MS subjects. The questions all relate to cognitive problems in daily life and are scored from 0 (never, does not occur) to 4 (very often, very disruptive) and a composite score is calculated, thus higher numbers indicate greater perceived CI. Assessed at baseline and after taking the study medication for 12 weeks. Perceived Deficits Questionnaire [ Time Frame: 12 weeks ] developed specifically for the MS

2016 Clinical Trials

33. An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction

,contain 23 items of the core symptoms of cognitive impairment. And the scale is used to measure the changes of symptoms of Chinese medicine before and after treatment. Other Outcome Measures: whole blood cell test [ Time Frame: 90 days ] blood routine test routine urine test [ Time Frame: 90 days ] routine urine test Liver function [ Time Frame: 90 days ] test the blood to detect the liver function,such as alanine aminotransferase(ALT) ,aspartate aminotransferase(AST),total bilirubin (TBIL), γ (...) An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2016 Clinical Trials

34. Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning

Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning Key Points • Regular use refers to weekly or more frequent cannabis use over a period of months to years. Regular cannabis use is associated with mild cognitive difficulties, which are typically not apparent following about one month of abstinence. Heavy (daily) and long-term cannabis use is related to more noticeable cognitive impairment. • Cannabis use beginning prior to the age of 16 or 17 is one of the strongest (...) predictors of cognitive impairment. However, it is unclear which comes first — whether cognitive impairment leads to early onset cannabis use or whether beginning cannabis use early in life causes a progressive decline in cognitive abilities. • Regular cannabis use is associated with altered brain structure and function. Once again, it is currently unclear whether chronic cannabis exposure directly leads to brain changes or whether differences in brain structure precede the onset of chronic cannabis use

2019 Canadian Centre on Substance Abuse

35. Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning

Clearing the Smoke on Cannabis: Regular Use and Cognitive Functioning Key Points • Regular use refers to weekly or more frequent cannabis use over a period of months to years. Regular cannabis use is associated with mild cognitive difficulties, which are typically not apparent following about one month of abstinence. Heavy (daily) and long-term cannabis use is related to more noticeable cognitive impairment. • Cannabis use beginning prior to the age of 16 or 17 is one of the strongest (...) predictors of cognitive impairment. However, it is unclear which comes first — whether cognitive impairment leads to early onset cannabis use or whether beginning cannabis use early in life causes a progressive decline in cognitive abilities. • Regular cannabis use is associated with altered brain structure and function. Once again, it is currently unclear whether chronic cannabis exposure directly leads to brain changes or whether differences in brain structure precede the onset of chronic cannabis use

2019 Canadian Centre on Substance Abuse

36. An international road map to improve pain assessment in people with impaired cognition: the development of the Pain Assessment in Impaired Cognition (PAIC) meta-tool. (PubMed)

, face and construct validity, responsiveness and usability, and are not internationally implemented. The EU-COST initiative "Pain in impaired cognition, especially dementia" aims to combine the expertise of clinicians and researchers to address this important issue by building on previous research in the area, identifying existing pain assessment tools for dementia, and developing consensus for items for a new universal meta-tool for use in research and clinical settings. This paper reports (...) on the initial phase of this collaboration task.All existing observational pain behaviour tools were identified and elements categorised using a three-step reduction process. Selection and refinement of items for the draft Pain Assessment in Impaired Cognition (PAIC) meta-tool was achieved through scrutiny of the evidence, consensus of expert opinion, frequency of use and alignment with the American Geriatric Society guidelines. The main aim of this process was to identify key items with potential empirical

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2014 BMC Neurology

37. Mindfulness-based interventions for improving cognition, academic achievement, behavior and socio-emotional functioning of primary and secondary students

Characteristics of included studies: RCT and QED studies 84 8.4 Characteristics of single group pre-post test studies 108 8.5 Characteristics of single subject design studies 110 8.6 Excluded studies 114 8.7 Risk of bias table 116 8.8 Cognitive outcomes by study included in meta-analysis 134 8.9 Academic outcomes by study included in meta-analysis 135 8.10 Behavioral outcomes by study included in meta-analysis 136 8.11 Socioemotional outcomes by study included in meta-analysis 137 8.12 Risk of bias by study (...) achievement outcomes with youth in a primary or secondary school setting. MBIs are interventions that use a mindfulness component, broadly defined as “paying attention in a particularly way: on purpose, in the present moment, non-judgmentally”, often with other components, such as yoga, cognitive-behavioral strategies, or relaxation skills training. What studies are included? Included studies used a randomized controlled trial, quasi-experimental, single group pre-post test or single subject design

2017 Campbell Collaboration

38. Single screening questions for cognitive impairment in older people: a systematic review (PubMed)

Single screening questions for cognitive impairment in older people: a systematic review Single-item screening questions may be a practical first step in screening for cognitive problems in older people. A form of single-item cognitive assessment is proposed in the NHS England and Wales dementia strategy. We aimed to provide a review and synthesis of the evidence regarding the performance of single-item tests for detection of cognitive impairment.This review used Cochrane diagnostic test (...) accuracy procedures. Two independent researchers searched for relevant papers across multiple, cross-disciplinary electronic databases using previously validated search strings. Our index test was any single screening question for cognitive impairment, including factor analysis of multi-item tools. Our reference standards included clinical diagnosis and multi-domain cognitive assessments.From 884 titles, 11 studies were identified as eligible for inclusion. Four studies were graded low risk of bias

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2014 EvidenceUpdates

39. Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism

Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2017 Clinical Trials

40. Cognitive and Mind-Body Therapies for Chronic Low Back and Neck Pain: Effectiveness and Value

Report List of Acronyms Used in this Report AAPM American Academy of Pain Medicine AHRQ Agency for Healthcare Research and Quality ACP American College of Physicians AMSTAR A Measurement Tool to Assess Systematic Reviews APS American Pain Society CBT Cognitive Behavioral Therapy CDC Centers for Disease Control and Prevention CMS Centers for Medicare and Medicaid Services CPGS Chronic Pain Grade Scale FFbHR Functional questionnaire Hannover for everyday diagnosis of functional impairment by back pain (...) of cognitive and mind-body therapies for chronic neck pain. Comparative Clinical Effectiveness We abstracted data on the interventions considered in this review from the AHRQ systematic review of therapies for low back pain and from subsequent randomized trials of the same interventions for patients with chronic low back pain. Evidence on intervention effectiveness focused on studies of at least six months’ duration or studies of more limited duration with outcomes assessed at least four weeks after

2017 California Technology Assessment Forum

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