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Six Item Cognitive Impairment Test

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241. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder

) and the Department of Defense (DoD) released an updated clinical practice guideline (CPG) on the treatment of PTSD. 9 This CPG was based on literature available through March 2016, and it addressed pharmacologic and nonpharmacologic (including complementary and integrative health) interventions for PTSD. 9 The CPG recommended individual, manualized trauma-focused psychotherapy with exposure and/or cognitive restructuring, such as prolonged exposure (PE), cognitive processing therapy (CPT), eye movement (...) desensitization and reprocessing (EMDR), specific cognitive behavioral therapies (CBT) for PTSD, brief eclectic psychotherapy (BEP), narrative exposure therapy (NET), and written narrative exposure. If trauma-focused psychotherapy is not readily available or not preferred, the CPG recommended individual non-trauma-focused psychotherapy or pharmacotherapy. Currently, only the selective serotonin reuptake inhibitors (SSRIs) sertraline and paroxetine are approved by the U.S. Food and Drug Administration (FDA

2019 Effective Health Care Program (AHRQ)

243. Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review

/progestin reduced clinical fractures (high SOE) and hip fractures (moderate SOE). After 3–5 years of prior treatment, continuation of zoledronate or alendronate versus drug holiday inconsistently reduced incident vertebral fracture outcomes (radiographic only for zoledronate [low SOE], clinical only for alendronate [moderate SOE]), but did not reduce nonvertebral fractures (low SOE). Hormone therapies increased cardiovascular events, mild cognitive impairment or dementia, and other harms. Observational (...) denosumab treatment, it was not possible to conclude anything about the risk of harms of long-term denosumab compared with placebo from the one study that met eligibility for this review. 18 In long-term trials of oral hormone therapy, specifically estrogen/progestin and estrogen versus placebo in postmenopausal women with unknown osteoporosis or osteopenia status, risk was significantly increased for cardiovascular disease, and mild cognitive impairment or dementia. 44-47 Risk for a composite outcome

2019 Effective Health Care Program (AHRQ)

244. BSG consensus guidelines on the management of inflammatory bowel disease in adults

, cognitive behavioural therapy, CBT, smoking Abbreviations 5-ASA: 5-aminosalicylate; AIDS: acquired immunodeficiency syndrome; ASUC: acute severe ulcerative colitis; AXR: abdominal x-ray; BCG: Bacillus Calmette-Guérin (TB vaccination); BMI: Body Mass Index; BSG: British Society of Gastroenterology; CBD: cannabinoid; CDAI: Crohn’s Disease Activity Index; CAMs: complementary and alternative medicines; CDEIS: Crohn’s Disease Endoscopic Index of Severity; CDI: Clostridium difficile infection; CI: Confidence (...) anastomosis; i.v.: intravenous; LFTs: liver function tests; MDT: multidisciplinary team; MeMP: methylmercaptopurine; MMR: measles mumps and rubella; MMX: Multi Matrix; MRE: magnetic resonance enterography; MRI: magnetic resonance imaging; NHS: national health service; NICE: Accepted manuscript 5 Version accepted by Gut 10 th June 2019 National Institute for Health and Care Excellence; NSAID: non-steroidal anti-inflammatory drug; OFG: orofacial granulomatosis; OR: odds ratio; PCR: polymerase chain reaction

2019 British Society of Gastroenterology

245. Treatment of Diabetes in Older Adults Full Text available with Trip Pro

). (Ungraded Good Practice Statement) 3.2 In patients aged 65 years and older with diabetes, we suggest that periodic cognitive screening should be performed to identify undiagnosed cognitive impairment. (2|⊕⊕OO) Technical remark: Use of validated self-administered tests is an efficient and cost-effective way to implement screening (see text). Alternative screening test options, such as the Mini-Mental State Examination or Montreal Cognitive Assessment, are widely used. An initial screening should (...) be performed at the time of diagnosis or when a patient enters a care program. Screening should be repeated every 2 to 3 years after a normal screening test result for patients without cognitive complaints or repeated 1 year after a borderline normal test result. Always evaluate cognitive complaints and assess cognition in patients with complaints. 3.3 In patients aged 65 years and older with diabetes and a diagnosis of cognitive impairment ( i.e. , mild cognitive impairment or dementia), we suggest

2019 The Endocrine Society

246. Autologous haematopoietic stem cell transplant for patients with highly active relapsing remitting multiple sclerosis not responding to high efficacy disease modifying therapies

in this trial. Mean follow-up for this preliminary analysis was 2.8 years. The primary outcome was time to disease progression and assessment of this was blinded. AHSCT significantly prolonged time to disease progression compared with DMTs, hazard ratio (HR) 0.07 (95% confidence interval (CI) 0.02 to 0.24, p 6.0), or an increase of at least 1.0 for patients with moderate levels of disability (EDSS 2.0 to 6.0), on two evaluations six months apart after at least a year of treatment 8 . This may also (...) in Europe and other regions including Australia, Canada and Brazil, and includes all MS types 6, 15 . In NHSScotland, during the period 2009 to 2018, six AHSCT procedures were recorded in patients who had a diagnosis of multiple sclerosis (R Munro, Principal Information Analyst, ISD Scotland. Personal Communication, 18 June 2019). Data collated by the Scottish HSCT network indicates that at least 32 patients from Scotland have travelled abroad for AHSCT (see patient group submission, appendix 1

2019 SHTG Advice Statements

247. What is the evidence on the role of the arts in improving health and well-being? A scoping review

interventions in that they combine multiple different components that are all known to be health promoting (21). Arts activities can involve aesthetic engagement, involvement of the imagination, sensory activation, evocation of emotion and cognitive stimulation. Depending on its nature, an art activity may also involve social interaction, physical activity, engagement with themes of health and interaction with health-care settings (Fig. 1) (22).3 Fig. 1. A logic model linking the arts with health Responses (...) Sensory activation Evocation of emotion Cognitive stimulation Social interaction Physical activity Engagement with themes of health Interaction with health-care settingsWHAT IS THE EVIDENCE ON THE ROLE OF THE ARTS IN IMPROVING HEALTH AND WELL-BEING? A SCOPING REVIEW HEALTH EVIDENCE NETWORK SYNTHESIS REPORT 4 Each of the component parts of arts activities can trigger psychological, physiological, social and behavioural responses that are themselves causally linked with health outcomes

2019 WHO Health Evidence Network

248. Addressing Social Isolation To Improve the Health of Older Adults: A Rapid Review

, increasing access to and use of clinical preventive services and behavioral health care, and increasing access to healthy food to improve the health of older adults. 55 Physical activity in particular also been shown to have mild positive effects on cognition for adults both with and without cognitive impairment. 56 Health systems should target the interventions to the needs of their population and may want to consider piloting new efforts to address social isolation to improve health to inform future (...) . Sixteen studies were included: one good-quality randomized controlled trial [RCT], seven fair-quality studies (6 RCTs and 1 pre-post), and eight poor-quality studies (7 pre-post and 1 cross-sectional with post-test survey). Of the eight good- or fair-quality studies, five examined physical activity, two examined social interventions, and one examined an arts and recreation intervention. Two were associated with a positive effect on health outcomes: a resistance training, nutrition, and psychosocial

2019 Effective Health Care Program (AHRQ)

249. Optimal Exercise Programs for Patients With Peripheral Artery Disease: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

; MOS, Medical Outcomes Study; PAD, peripheral artery disease; PADQOL, Impact of PAD on Quality of Life Questionnaire ; PAQ, Peripheral Artery Questionnaire , ; SF, Short Form; 6-MWT, 6-minute walk test; VascuQoL, Vascular Quality of Life Questionnaire ; and WIQ, Walking Impairment Questionnaire. , , Questionnaire measures do not always improve even when treadmill walking performance or 6-MWT improves. For example, in the CLEVER randomized trial (Claudication: Exercise Versus Endoluminal (...) as a reproducible discomfort or fatigue in the muscles of the lower extremity that occurs with exertion and is relieved within 10 minutes of rest. Most people with PAD do not have classic claudication symptoms but still have significantly greater functional impairment and decline than people without PAD. This significant physical activity limitation results in functional impairment, mobility loss, and decreased quality of life. Improving functioning and quality of life is a major goal in the treatment

2019 American Gastroenterological Association Institute

250. Tobacco Cessation Treatment

to quit smoking completely and offered assis- tance todoso,althoughtheneedforpharmacotherapy should be evaluated on a case-by-case basis. Asking the 2 questions that comprise the Heaviness of Smoking Index is a simple, reliable, and validated test to assess the strength of a daily smoker’s nicotine dependence (33) (Table 1). The Heaviness of Smoking Index has been shown to have equivalent or stronger validity in predicting relapse back to smoking after a quit attempt than other longer tests (...) of nicotine depen- dence (e.g., Fagerstrom Test of Nicotine Dependence, the APA Diagnostic and Statistical Manual criteria for assess tobacco use disorder) (33). Understanding the strength of someone’s nicotine dependence is important for tailoring the intensity of treatment or dose of pharmaco- therapy recommended. Other indicators of nicotine dependence include early initiation of exposure to nico- tine, dif?culty reducing and/or refraining from smoking for extended periods of time (i.e., several hours

2019 American College of Cardiology

251. Optimal Care Pathway for Aboriginal and Torres Strait Islander people with cancer

. • Care coordination for each person should be informed by factors such as gender, kinship, family ties, language barriers and socio-economic issues. – Offer an option to see a health professional of the same gender as the patient, referral to an alternative service provider if this is not possible, or the option of having a support person present. – Acknowledge that family may include people who are not genetically related. • When discussing family history and genetic testing, understand (...) gender • feel culturally unsafe accessing health services • face financial, transport or other barriers to accessing health services • have family and community responsibilities • experience feelings of shame or discomfort from heightened attention, sharing personal information, previous experiences or perceptions about cancer or mainstream medical services. Referral: If test results are equivocal, or if the diagnosis of cancer is confirmed, referral to an appropriate specialist is warranted. Timely

2018 Cancer Australia

252. Standards for Studies of Neurological Prognostication in Comatose Survivors of Cardiac Arrest: A Scientific Statement From the American Heart Association

-of-life measures. Neurocognitive testing is underused in current outcomes assessment. Studies have identified deficits in memory, attention, and executive function as most common after cardiac arrest. Cognitive impairment can occur in up to 50% of survivors and is most often mild to moderate in severity. Standard neuropsychological testing is the gold standard but is limited by in-person testing by trained personnel. Highly suggested timing for testing is at ≥90 days. Comprehensive testing batteries (...) for critical care. Some patients may have expressed a desire not to receive aggressive critical care or prolonged support if permanent disabilities are anticipated. The sooner that the risk of impaired survival can be determined, the less exposure such a patient will have to unwanted interventions. The goal is to have an accurate, precise, and clinically applicable test for most patients after cardiac arrest that can be reliably applied as early as possible after resuscitation. In the era of targeted

2019 American Heart Association

253. Implementation of Supervised Exercise Therapy for Patients With Symptomatic Peripheral Artery Disease: A Science Advisory From the American Heart Association Full Text available with Trip Pro

questionnaires may be used to assess changes in patient-reported functional status and health-related quality of life with SET ( ). Improvement in walking ability may be noted in the Walking Impairment Questionnaire subscale scores and in the physical component summary score from the 36-Item Short Form Health Survey, but little change typically occurs in the mental component summary score. SET programs may choose to limit subjective assessment to subscales related to physical function. provides (...) Survey; VascuQoL-6, 6-Item Vascular Quality of Life Questionnaire; VascuQoL-25, 25-Item Vascular Quality of Life Questionnaire; and WIQ, Walking Impairment Questionnaire. *Item number depends on version type used for each domain. †Score range varies on the basis of measure type (computer-adaptive vs fixed-length short form). ‡Item not under a specific domain. Transition to Community-Based Exercise SET is a 12-week program with the option of a second program of 36 sessions with an additional referral

2019 American Heart Association

254. Clinical Practice Guidelines for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures

been two cohort studies, six RCTs, and five meta-analyses published since 2013 that report mortality and cardiovascular outcomes, such as myocardial infarction, stroke, CVD risk and events, hypertension (HTN), and dyslipidemia (31-43). Despite heterogeneity in study design, these data favor significantly improved CVD outcomes in patients undergoing bariatric surgery. DiaSurg 2, a randomized controlled multicenter trial comparing RYGB versus medical treatment in German patients with insulin (...) ). Patients with the following comorbidities and BMI =35 kg/m 2 may also be considered for a bariatric procedure though the strength of evidence is more variable: obesity- hypoventilation syndrome and Pickwickian syndrome after a careful evaluation of DOI:10.4158/GL-2019-0406 © 2019 AACE. 25 operative risk; idiopathic intracranial hypertension; gastroesophageal reflux disease; severe venous stasis disease; impaired mobility due to obesity; and considerably impaired quality of life (Grade C; BEL 3). R3

2019 American Association of Clinical Endocrinologists

255. Guidelines for Psychological Practice for People with Low-Income and Economic Marginalization

of children in America (Schickedanz, Dreyer, & Haffon, 2015). The needs and desires of LIEM populations are often neglected, or even ignored, for a multitude of potential reasons. One possibility has to do with a process called distancing. Lott (2002) identified distancing as a key factor in classist beliefs, defining classism as cognitive and behavioral distancing from people who are poor. In simpler terms, this means that classism is often perpetuated by sim- ply making poor people invisible to those

2019 American Psychological Association

256. Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts

Regarding Guideline Scope 80 Implications of Alignment with the Institute of Medicine Standards…………………………………………………………….82 Limitations of Existing Treatment Research Literature 87 Need for a Clearer Taxonomy of Psychotherapies 93 Need for Rigorous Comparisons of Treatments and Treatment Modality 94 Improving Methodology and Reporting in Treatment Studies 95 Testing Moderators and Mediators of Treatment Outcome 96 Funding Needs 97 Conclusion 98 Conflicts of Interest 99 Author Disclosures 102 Developer 106 (...) for cyclothymic disorder, and symptoms are not better explained by another disorder, cause significant impairment in functioning or distress, and are not due to a different medical condition or a substance use disorder (American Psychiatric Association, 2013). For patients that do not meet full criteria for the aforementioned depressive disorders (depressive episode with insufficient symptoms) but either experience recurrent episodes of depressed mood and at least four other symptoms of depression for 2–13

2019 American Psychological Association

257. AACE/ACE Guidelines for Management of Growth Hormone Deficiency in Adults and Patients Transitioning from Pediatric to Adult Care

(no clinical evidence). Conclusion: This CPG is a practical tool that prac- ticing endocrinologists and regulatory bodies can refer to regarding the identification, diagnosis, and treatment of adults and patients transitioning from pediatric to adult- care services with growth hormone deficiency (GHD). It provides guidelines on assessment, screening, diagnostic testing, and treatment recommendations for a range of individuals with various causes of adult GHD. The recom- mendations emphasize the importance (...) of considering test- ing patients with a reasonable level of clinical suspicion of GHD using appropriate growth hormone (GH) cut-points for various GH–stimulation tests to accurately diagnose adult GHD, and to exercise caution interpreting serum GH and insulin-like growth factor-1 (IGF-1) levels, as various GH and IGF-1 assays are used to support treatment deci- sions. The intention to treat often requires sound clinical judgment and careful assessment of the benefits and risks specific to each individual

2019 American Association of Clinical Endocrinologists

258. ASCIA Guidelines: Chronic Spontaneous Urticaria (CSU)

is superior to second generation antihistamines despite carrying a higher degree of sedation, anticholinergic effects and cognitive impairment (Grant et al, 1998; Monroe et al, 1992; Monroe, 1992; Breneman, 1996; Kalivas et al, 1990; Shamsi & Hindmarch, 2000). Randomised controlled trials comparing loratadine vs hydroxyzine (not available in Australia) (Monroe et al, 1992; Monroe, 1992) and cetirizine vs hydroxyzine (Breneman, 1996; Kalivas et al, 1990) did not demonstrate any significant difference (...) in this document ASST autologous serum skin test CIndU chronic inducible urticaria CSU chronic spontaneous urticaria CU-Q2oL chronic urticaria quality of life questionnaire DLQI dermatology life quality index EAACI European Academy of Allergology and Clinical Immunology EDF European Dermatology Forum GA 2 LEN Global Allergy and Asthma European Network IgE Immunoglobulin E IVIg Intravenous immunoglobulin LTRA leukotriene receptor antagonists QoL quality of life TNF tumour necrosis factor UAS urticaria activity

2019 Australasian Society of Clinical Immunology and Allergy

260. Prostate Cancer

in the Era of the U.S. Preventive Services Task Force Recommendation against Prostate Specific Antigen Based Screening. J Urol, 2016. 195: 66. 91. Grossman, D.C., et al. Screening for Prostate Cancer: US Preventive Services Task Force Recommendation Statement. Jama, 2018. 319: 1901. 92. U.S. Preventive Services, Task Force. Prostate Cancer Screening Draft Recommendations. 2017. 93. Arnsrud Godtman, R., et al. Opportunistic testing versus organized prostate-specific antigen screening: outcome after 18 (...) years in the Goteborg randomized population-based prostate cancer screening trial. Eur Urol, 2015. 68: 354. 94. Ilic, D., et al. Screening for prostate cancer. Cochrane Database Syst Rev, 2013. 1: CD004720. 95. Hayes, J.H., et al. Screening for prostate cancer with the prostate-specific antigen test: a review of current evidence. JAMA, 2014. 311: 1143. 96. Booth, N., et al. Health-related quality of life in the Finnish trial of screening for prostate cancer. Eur Urol, 2014. 65: 39. 97. Vasarainen, H

2019 European Association of Urology

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