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Sinus Tachycardia

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1. Pharmacological interventions for clozapine-induced sinus tachycardia. (Full text)

Pharmacological interventions for clozapine-induced sinus tachycardia. Clozapine is an efficacious treatment for treatment-resistant schizophrenia; however its use can be limited by side effect intolerability. Sinus tachycardia is a common adverse event associated with clozapine treatment. Various pharmacological treatments are used to control heart rate increase due to clozapine use and can include a decreased rate of clozapine titration, a switch to a different antipsychotic, or treatment (...) with negative chronotropic drugs.To assess the clinical effects and efficacy of pharmacological interventions for clozapine-induced sinus tachycardia.To systematically review the adverse events associated with pharmacological interventions for clozapine-induced sinus tachycardia.On 23 March 2015, we searched the Cochrane Schizophrenia Group's Study-Based Register of Trials, which is based on regular searches of CINAHL, BIOSIS, AMED, EMBASE, PubMed, MEDLINE, PsycINFO and registries of clinical trials

2016 Cochrane PubMed

2. Management of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope (Full text)

Management of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope Postural tachycardia syndrome (POTS), inappropriate sinus tachycardia (IST) and vasovagal syncope (VVS) are relatively common clinical syndromes that are seen by physicians in several disciplines. They are often not well recognised and are poorly understood by physicians, are associated with significant morbidity and cause significant frustration for both patients and their physicians. The 2015 (...) Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope provides physicians with an introduction to these disorders and initial recommendations on their investigation and treatment. Here we summarise the consensus statement to help physicians in the management of patients with these frequently distressing problems.

2016 Arrhythmia & electrophysiology review PubMed

3. Alcohol withdrawal and sinus tachycardia

Alcohol withdrawal and sinus tachycardia Dr. Smith's ECG Blog: Alcohol withdrawal and sinus tachycardia Thursday, March 8, 2018 This patient with alcohol withdrawal and tachycardia had an ECG recorded: What do you think? There is sinus tachycardia. Look at the QT interval: it is far more than half the QT. The computer reads the QT at 386 ms, and QTc of 462 (proprietary correction formula unknown!) Read this article: I measure the QT at 440 ms. RR interval is 470 ms. It is possible that what we (...) waves with normal PR interval that suggest sinus rhythm. Looking down at simultaneously-recorded lead V2 confirms sinus activity — which tells us that the overly wide upright deflection toward the end of the R-R interval in lead II is at least partially made up of a sinus P wave. So the rhythm is sinus tachycardia with a VERY long QT interval. This should immediately suggest the common causes of a long QTc = i) Drugs; ii) Serum Electrolyte Disorders (including low K+, low Mg++ and low Ca++); and CNS

2018 Dr Smith's ECG Blog

4. Chest pain, sinus tachycardia, and ST Elevation

Chest pain, sinus tachycardia, and ST Elevation Dr. Smith's ECG Blog: Chest pain, sinus tachycardia, and ST Elevation Monday, January 22, 2018 I was reading through ECGs on the system when I saw this one: Sinus tachycardia, rate 120 Computerized QTc = 380 ms What do you think? I was immediately worried about a proximal LAD occlusion. Although sinus tachycardia generally argues against ACS, a large anterior MI may result in such poor stroke volume that there is compensatory tachycardia

2018 Dr Smith's ECG Blog

5. Entrapment of focal atrial tachycardia using cryoballoon ablation; Sinus rhythm in the left atrium and ongoing atrial tachycardia in the left atrial appendage (Full text)

Entrapment of focal atrial tachycardia using cryoballoon ablation; Sinus rhythm in the left atrium and ongoing atrial tachycardia in the left atrial appendage Left atrial appendage (LAA) is a well-known source of focal atrial tachycardias (AT). Although radio-frequency (RF) energy is the most commonly used technique in such cases, there was an option other than epicardial approach when RF technique fails. Cryoballoon technology is primarily developed to be used for pulmonary vein isolation (PVI (...) ). Also, there was no report regarding the isolation of LAA by using cryo-balloon in patients with focal AT. In this case, for the first time in the literature, we successfully isolated the LAA because of failed attempts of RF ablation for focal AT in whom the surface electrogram showed a sinus rhythm while arrhythmia continues inside the LAA.Copyright © 2017 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. All rights reserved.

2017 Indian pacing and electrophysiology journal PubMed

6. Late Outcomes of Surgical Ablation for Inappropriate Sinus Tachycardia. (PubMed)

Late Outcomes of Surgical Ablation for Inappropriate Sinus Tachycardia. Inappropriate sinus tachycardia (IST) is a rare clinical disorder characterized by an elevated resting heart rate and an exaggerated rate response to exercise or autonomic stress. Pharmacological therapy and catheter ablation are considered first-line treatments for IST but can yield sub-optimal relief of symptoms. The results of surgical ablation at our center were reviewed for patients with refractory IST.Between 1987 (...) and 2018, 18 patients underwent surgical sinoatrial (SA) node isolation for treatment-refractory IST. All 18 patients had previously failed pharmacological therapy, and 15 patients had failed catheter ablation of the SA node.Ten patients underwent a median sternotomy, and eight patients underwent a minimally invasive right thoracotomy. The SA node was isolated using surgical incisions, cryoablation, and/or bipolar radiofrequency ablations. Sinus tachycardia was eliminated in 100% of patients

2019 Annals of Thoracic Surgery

7. Isolation of the conduction between the Marshall bundle and distal coronary sinus and the entire coronary sinus for an atrial tachycardia after catheter ablation of atrial fibrillation (Full text)

Isolation of the conduction between the Marshall bundle and distal coronary sinus and the entire coronary sinus for an atrial tachycardia after catheter ablation of atrial fibrillation 28748145 2019 02 26 2214-0271 3 7 2017 Jul HeartRhythm case reports HeartRhythm Case Rep Isolation of the conduction between the Marshall bundle and distal coronary sinus and the entire coronary sinus for an atrial tachycardia after catheter ablation of atrial fibrillation. 360-363 10.1016/j.hrcr.2017.05.012 (...) of Cardiology, Showa University Fujigaoka Hospital, Yokohama, Japan. eng Case Reports 2017 06 03 United States HeartRhythm Case Rep 101656239 2214-0271 Atrial tachycardia Catheter ablation Coronary sinus musculature Marshall bundle 2017 7 28 6 0 2017 7 28 6 0 2017 7 28 6 1 epublish 28748145 10.1016/j.hrcr.2017.05.012 S2214-0271(17)30095-7 PMC5511981 Circulation. 2000 Apr 4;101(13):1503-5 10747341 Heart Rhythm. 2006 Dec;3(12):1505-7 17161799 Heart Rhythm. 2009 Dec;6(12 Suppl):S35-40 19959141 J Cardiovasc

2017 HeartRhythm Case Reports PubMed

8. The use of a novel signal analysis to identify the origin of idiopathic right ventricular outflow tract ventricular tachycardia during sinus rhythm: Simultaneous amplitude frequency electrogram transformation mapping. (Full text)

The use of a novel signal analysis to identify the origin of idiopathic right ventricular outflow tract ventricular tachycardia during sinus rhythm: Simultaneous amplitude frequency electrogram transformation mapping. The signal characteristics of intracardiac bipolar electrograms at the origin of idiopathic RVOT-VT during sinus rhythm remain unclear.The study sought to develop a novel real-time/online technique, simultaneous amplitude frequency electrogram transformation (SAFE-T), to quantify (...) and localize the diseased ventricular substrate in idiopathic RVOT-VT.We retrospectively investigated the intracardiac bipolar recordings in 70 consecutive patients (26% male, mean age 42±12 years) who underwent successful radiofrequency catheter ablation of idiopathic RVOT-VT. We quantified the extent of the frequency fraction of ventricular potentials during sinus rhythm or ventricular pacing using a novel formula, the product of instantaneous amplitude and frequency, and showed that in a 3D geometry

2017 PLoS ONE PubMed

9. Control of sinus tachycardia as an additional therapy in patients with decompensated heart failure (CONSTATHE-DHF): A randomized, double-blind, placebo-controlled trial. (PubMed)

Control of sinus tachycardia as an additional therapy in patients with decompensated heart failure (CONSTATHE-DHF): A randomized, double-blind, placebo-controlled trial. 27469019 2018 08 31 2018 12 02 1557-3117 35 10 2016 10 The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation J. Heart Lung Transplant. Control of sinus tachycardia as an additional therapy in patients with decompensated heart failure (CONSTATHE-DHF (...) Cardiovascular Agents administration & dosage Dose-Response Relationship, Drug Double-Blind Method Female Follow-Up Studies Heart Failure complications drug therapy physiopathology Heart Rate drug effects physiology Humans Ivabradine Male Middle Aged Tachycardia, Sinus drug therapy etiology physiopathology Time Factors Treatment Outcome 2015 12 08 2016 05 03 2016 06 01 2016 10 25 6 0 2018 9 1 6 0 2016 7 30 6 0 ppublish 27469019 S1053-2498(16)30172-3 10.1016/j.healun.2016.06.005

2018 The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

10. P‐Wave Amplitude and PR Changes in Patients With Inappropriate Sinus Tachycardia: Findings Supportive of a Central Mechanism (Full text)

P‐Wave Amplitude and PR Changes in Patients With Inappropriate Sinus Tachycardia: Findings Supportive of a Central Mechanism The mechanism of inappropriate sinus tachycardia (IST) remains incompletely understood.We prospectively compared 3 patient groups: 11 patients with IST (IST Group), 9 control patients administered isoproterenol (Isuprel Group), and 15 patients with cristae terminalis atrial tachycardia (AT Group). P-wave amplitude in lead II and PR interval were measured at a lower (...) was noted in the Isuprel Group (P=0.6). In contrast, patients in the atrial tachycardia Group experienced PR lengthening during atrial tachycardia when compared with baseline normal sinus rhythm (153±25 ms at HR1=78±17 beats per minute versus 179±29 ms at HR2=140±28 beats per minute, P<0.01).We have shown that HR increases in patients with IST were associated with an increase in P-wave amplitude in lead II and PR shortening similar to what is seen in healthy controls following isoproterenol infusion

2018 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease PubMed

11. Catheter ablation of the slow pathway as a treatment for severe sinus node dysfunction in a patient with incessant atrioventricular nodal reentry tachycardia (Full text)

Catheter ablation of the slow pathway as a treatment for severe sinus node dysfunction in a patient with incessant atrioventricular nodal reentry tachycardia 29707487 2019 02 26 2214-0271 4 3 2018 Mar HeartRhythm case reports HeartRhythm Case Rep Catheter ablation of the slow pathway as a treatment for severe sinus node dysfunction in a patient with incessant atrioventricular nodal reentry tachycardia. 113-116 10.1016/j.hrcr.2017.12.007 Margolis Gilad G Department of Cardiology, Tel Aviv (...) University, Tel Aviv, Israel. eng Case Reports 2018 01 06 United States HeartRhythm Case Rep 101656239 2214-0271 Ablation Atrioventricular nodal reentry tachycardia Brady-tachycardia syndrome Sinus node dysfunction Slow pathway 2018 5 1 6 0 2018 5 1 6 0 2018 5 1 6 1 epublish 29707487 10.1016/j.hrcr.2017.12.007 S2214-0271(17)30218-X PMC5918186 J Cardiovasc Electrophysiol. 1998 May;9(5):470-8 9607454 Pacing Clin Electrophysiol. 1979 May;2(3):325-9 95297 Circulation. 1992 May;85(5):1675-88 1572026 N Engl J

2018 HeartRhythm Case Reports PubMed

12. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. (Full text)

Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. There is no nonparenteral medication for the rapid termination of paroxysmal supraventricular tachycardia.The purpose of this study was to assess the efficacy and safety of etripamil nasal spray, a short-acting calcium-channel blocker, for the rapid termination of paroxysmal supraventricular tachycardia (SVT).This phase 2 study was performed during electrophysiological testing in patients with previously (...) documented SVT who were induced into SVT prior to undergoing a catheter ablation. Patients in sustained SVT for 5 min received either placebo or 1 of 4 doses of active compound. The primary endpoint was the SVT conversion rate within 15 min of study drug administration. Secondary endpoints included time to conversion and adverse events.One hundred four patients were dosed. Conversion rates from SVT to sinus rhythm were between 65% and 95% in the etripamil nasal spray groups and 35% in the placebo group

2018 Journal of the American College of Cardiology PubMed

13. Successful Ablation for Atrial Tachycardia Originated from Sinus Venosa with Tachycardia-Induced Cardiomyopathy (Full text)

Successful Ablation for Atrial Tachycardia Originated from Sinus Venosa with Tachycardia-Induced Cardiomyopathy A 74-year-old male suffering from congestive heart failure with atrial tachycardia (AT) with 2 : 1 atrioventricular conduction was admitted to our hospital. After the therapy with diuretics and β-blocker, his rapid AT was still sustained. He took the catheter ablation for his AT. Postpacing interval mapping from entrainment and noncontact mapping system revealed the mechanism of his (...) AT, originated from sinus venosa. His AT was successfully terminated and eliminated by radiofrequency catheter ablation. After the successful ablation, he has been free from any AT, and his cardiac function was also improved.

2016 Case reports in cardiology PubMed

14. Interesting electrophysiological findings in a patient with coexistence of atrial tachycardia originating from coronary sinus and slow-fast atrioventricular nodal reentrant tachycardia (Full text)

Interesting electrophysiological findings in a patient with coexistence of atrial tachycardia originating from coronary sinus and slow-fast atrioventricular nodal reentrant tachycardia Slow-fast atrioventricular nodal tachycardia (AVNRT) has various electrophysiological aspects due to atrioventricular (AV) nodal physiology. In addition, concomitantly another form of arrhythmia with AVNRT, especially atrial tachycardia (AT), was an infrequent arrhythmia. A 38-year-old female with narrow QRS (...) tachycardia underwent electrophysiological study due to frequent faintness. The electrophysiological study disclosed the coexistence of AT originating from coronary sinus (CS) with slow-fast AVNRT. We easily diagnosed AT originating from CS and terminated with several radiofrequency ablations (RFA) around CS. The diagnosis of slow-fast AVNRT, however, was somewhat difficult due to the following findings: (1) small amount of adenosine triphosphate (ATP) could terminate slow-fast AVNRT reproducibly; (2) we

2016 Journal of cardiology cases PubMed

15. Comparison of Treatment of Supraventricular Tachycardia by Valsalva Maneuver and Carotid Sinus Massage. (PubMed)

Comparison of Treatment of Supraventricular Tachycardia by Valsalva Maneuver and Carotid Sinus Massage. To compare the efficacy of the Valsalva maneuver with that of carotid sinus massage (CSM) in terminating paroxysmal supraventricular tachycardia (SVT) in the ED.This prospective, randomized case study was performed in the ED of a tertiary care institution. Patients were at least 10 years of age with regular narrow complex tachycardia and had an ECG diagnosis of SVT. Patients with regular (...) with the Valsalva maneuver (success rate 16.9%). The Valsalva maneuver and CSM achieved conversion in a total of 41 instances of SVT (success rate 27.7%).Vagal maneuvers are efficacious in terminating about one quarter of spontaneous SVT cases. There is no detectable difference in efficacy between the Valsalva maneuver and CSM. [Lim SH, Anantharaman V, Teo WS, Goh PP, Tan ATH: Comparison of treatment of supraventricular tachycardia by Valsalva maneuver and carotid sinus massage. Ann Emerg Med January 1998;31:30

2017 Annals of Emergency Medicine

16. Pregnancy Related Inappropriate Sinus Tachycardia

Pregnancy Related Inappropriate Sinus Tachycardia Pregnancy Related Inappropriate Sinus Tachycardia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pregnancy Related Inappropriate Sinus Tachycardia (PRIST (...) Information provided by (Responsible Party): Dr Mark Belham, Cambridge University Hospitals NHS Foundation Trust Study Details Study Description Go to Brief Summary: A feasibility study into the exploration of possible mechanisms underlying inappropriate sinus tachycardia (IST) syndrome in pregnancy. Condition or disease Intervention/treatment Inappropriate Sinus Tachycardia Pregnancy Related Diagnostic Test: ECG Diagnostic Test: heart rate monitor Diagnostic Test: Autonomic Nervous System (ANS) Activity

2017 Clinical Trials

17. Inappropriate Sinus Tachycardia - Symptom And Heart Rate Reduction with Ivabradine: Pooled Analysis of Prospective Studies. (PubMed)

Inappropriate Sinus Tachycardia - Symptom And Heart Rate Reduction with Ivabradine: Pooled Analysis of Prospective Studies. Inappropriate sinus tachycardia (IST) is debilitating despite available treatment. Off-label use of ivabradine for IST prompted this systematic analysis of existing data quality and sample size estimates for adequately powered studies.To determine clinical efficacy of ivabradine in IST from pooled prospective studies.Analysis included ivabradine studies for IST

2017 Heart Rhythm

18. Sinus Tachycardia With Variable QRS Morphology. (PubMed)

Sinus Tachycardia With Variable QRS Morphology. Wolff-Parkinson-White-type ventricular preexcitation was recognized for the first time in a 67-year-old man four days after aortic valve replacement. The preexcitation was intermittent.Copyright © 2017 Elsevier Inc. All rights reserved.

2017 American Journal of Cardiology

19. Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW). (Full text)

Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW). Alcohol is a risk factor for cardiac arrhythmias. Retrospective analyses suggest supraventricular arrhythmias consecutive to acute alcohol consumption, but prospective data are limited. We intended to prospectively associate acute alcohol consumption with cardiac arrhythmias.At the 2015 Munich Octoberfest, we enrolled 3028 (...) voluntary participants who received a smartphone-based ECG and breath alcohol concentration (BAC) measurements. ECGs were analysed for cardiac arrhythmias (sinus tachycardia, sinus arrhythmia, premature atrial/ventricular complexes, atrial fibrillation/flutter) and respiratory sinus arrhythmia. By multivariable adjusted logistic regression we associated BACs with cardiac arrhythmias. Similarly, we analysed 4131 participants of the community-based KORA S4 Study (Co-operative Health Research in the Region

2017 European Heart Journal PubMed

20. Epidemiology and definition of inappropriate sinus tachycardia.

Epidemiology and definition of inappropriate sinus tachycardia. Inappropriate sinus tachycardia (IST) is a clinical syndrome lacking formal diagnostic criteria. It is generally defined as an elevated resting heart rate (HR; >90-100 bpm) with an exaggerated response to physical or emotional stress and a clearly sinus mechanism. Clinical manifestations are broad from a complete lack of symptoms to incapacitating incessant tachycardia. Now understood to be relatively prevalent, it is observed (...) to have a generally benign prognosis, though symptoms may persist for years. Whether IST is a single discrete entity or a heterogeneous condition with overlap to other syndromes such as postural orthostatic tachycardia syndrome remains a matter of debate.

2017 Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

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