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Shock Index

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121. Shock Index and Prediction of Traumatic Hemorrhagic Shock 28-Day Mortality: Data from the DCLHb Resuscitation Clinical Trials Full Text available with Trip Pro

Shock Index and Prediction of Traumatic Hemorrhagic Shock 28-Day Mortality: Data from the DCLHb Resuscitation Clinical Trials To assess the ability of the shock index (SI) to predict 28-day mortality in traumatic hemorrhagic shock patients treated in the diaspirin cross-linked hemoglobin (DCLHb) resuscitation clinical trials.We used data from two parallel DCLHb traumatic hemorrhagic shock efficacy trials, one in U.S. emergency departments, and one in the European Union prehospital setting (...) patients with SI values below these cutoffs (p<0.001). Similarly, after 120 minutes of resuscitation, patients with a SI≥1.0 were 3.9× times more likely to die by 28 days (40 vs. 15%, p<0.001). Although the distribution of SI values differed based on treatment group, the receiver operator characeristics data showed no difference in SI predictive ability for 28-day mortality in patients treated with DCLHb.In these traumatic hemorrhagic shock patients, the shock index correlates with 28-day mortality

2014 Western Journal of Emergency Medicine

122. Prognostic role of the simplified pulmonary embolism severity index and shock index in pulmonary embolism. (Abstract)

Prognostic role of the simplified pulmonary embolism severity index and shock index in pulmonary embolism. The stratification of acute pulmonary embolism (PE) using the simplified pulmonary embolism severity index (sPESI) and shock index (SI) does not require any prognostic tools such as biomarkers or echocardiography.We compared the ability of the sPESI and SI to predict 30-day and 3-year mortality following PE.Prognostic models based on the sPESI and SI were used to predict the overall 30-day

2014 Polskie Archiwum Medycyny Wewnetrznej

123. Geriatric nutritional risk index is associated with 30-day mortality in patients with acute respiratory distress syndrome. Full Text available with Trip Pro

Geriatric nutritional risk index is associated with 30-day mortality in patients with acute respiratory distress syndrome. The clinical effect of the geriatric nutritional risk index (GNRI) on patients with acute respiratory distress syndrome (ARDS) remains unclear. The aim of this study was to evaluate the association between the GNRI on admission and 30-day mortality in patients with ARDS. From January 2014 to May 2019, we retrospectively reviewed medical records for patients with ARDS (...) admitted to a medical intensive care unit, who met for the Berlin definition. The GNRI was calculated as follows: 1.519 × serum albumin, (g/L) + (41.7 × present weight, kg/ideal body weight, kg). Clinical data of 224 patients were analyzed. Median age was 72 years old and 71.4% was men. ARDS was mostly of pulmonary origin (94.2%). 30-day mortality was 61.6% (138/224). APACHE II and SOFA scores and the frequency of septic shock and acute kidney injury, were significantly higher in non-survivors

2020 Medicine

124. Impact of norepinephrine on right ventricular afterload and function in septic shock-a strain echocardiography study. (Abstract)

Impact of norepinephrine on right ventricular afterload and function in septic shock-a strain echocardiography study. In this observational study, the effects of norepinephrine-induced changes in mean arterial pressure (MAP) on right ventricular (RV) systolic function, afterload and pulmonary haemodynamics were studied in septic shock patients. We hypothesised that RV systolic function improves at higher doses of norepinephrine/MAP levels.Eleven patients with septic shock requiring (...) elastance, (Epa ) and pulmonary vascular resistance index, (PVRI). RV free wall peak strain was the primary end-point.At highest compared to lowest norepinephrine dose/MAP level, RV free wall peak strain increased from -19% to -25% (32%, P = .003), accompanied by increased tricuspid annular plane systolic excursion (22%, P = .01). At the highest norepinephrine dose/MAP, RV end-diastolic area index (16%, P < .001), central venous pressure (38%, P < .001), stroke volume index (7%, P = .001), mean

2019 Acta Anaesthesiologica Scandinavica

125. Circulating dipeptidyl peptidase 3 and alteration in haemodynamics in cardiogenic shock: results from the OptimaCC trial. (Abstract)

(SAPS II), lower cardiac index and lower estimated glomerular filtration rate. More importantly, in CS patients with high cDPP3 at inclusion, those who rapidly decreased cDPP3 at 24 h exhibited a striking reduction in the occurrence of refractory shock and death.In CS patients, cDPP3 gives an early prediction of outcome, including development of refractory status and/or survival.clinicaltrials.gov Identifier NCT01367743.© 2019 The Authors. European Journal of Heart Failure © 2019 European Society (...) Circulating dipeptidyl peptidase 3 and alteration in haemodynamics in cardiogenic shock: results from the OptimaCC trial. Dipeptidyl peptidase 3 (DPP3) is a protease involved in the degradation of cardiovascular mediators. Its administration has been shown to be associated with impaired cardiac contraction and kidney haemodynamics while its inhibition restored cardiac contraction in a pre-clinical model of severe heart failure in mice. Circulating DPP3 (cDPP3) was found to be elevated in shock

2019 European Journal of Heart Failure Controlled trial quality: predicted high

126. Heat shock protein 70 protects the quail cecum against oxidant stress, inflammatory injury, and microbiota imbalance induced by cold stress. Full Text available with Trip Pro

Heat shock protein 70 protects the quail cecum against oxidant stress, inflammatory injury, and microbiota imbalance induced by cold stress. The intent of this study was to investigate the effects of cold stress on oxidative indexes, inflammatory factors, and microbiota in the quail cecum. A total of 192 male quails (15-day-old) were randomly divided into 12 groups (16 in each group) and were exposed to acute (up to 12 h) and chronic (up to 20 D) cold stress at 12 ± 1°C. After cold stress (...) treatment, we examined morphological damage, oxidative stress indexes, inflammatory factors, and intestinal microbiota. Results of morphological examination showed that both acute and chronic cold stress can lead to cecal tissue injury. In addition, both acute and chronic cold stress, especially chronic cold stress can influence the activity of oxidative stress mediators. Glutathione (GSH) and glutathione peroxidase (GSH-Px) activities decreased significantly (p < 0.05), while the nitric oxide

2019 Poultry science Controlled trial quality: uncertain

127. Comments on GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: A randomized controlled trial. (Abstract)

0735-6757 IM Global end-diastolic volume index (GEDI) Sepsis Septic shock 2019 02 18 2019 02 27 2019 3 25 6 0 2019 3 25 6 0 2019 3 26 6 0 ppublish 30905478 S0735-6757(19)30145-7 10.1016/j.ajem.2019.02.041 (...) Comments on GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: A randomized controlled trial. 30905478 2019 08 26 1532-8171 37 9 2019 Sep The American journal of emergency medicine Am J Emerg Med Comments on GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: A randomized controlled trial. 1793-1794 S0735-6757(19)30145-7 10.1016/j.ajem.2019.02.041 Feng Wenwei W Department of Cardiology, Dongguan Traditional Chinese Medicine

2019 The American journal of emergency medicine Controlled trial quality: predicted high

128. The effect of extracorporeal shock wave therapy on the treatment of moderate to severe knee osteoarthritis and cartilage lesion. Full Text available with Trip Pro

The effect of extracorporeal shock wave therapy on the treatment of moderate to severe knee osteoarthritis and cartilage lesion. Knee osteoarthritis (KOA) is a major cause leading to chronic bone and muscle pain. Extracorporeal shock wave therapy (ESWT) has been applied in treating KOA in recent years.From April 2016 to April 2017, 82 patients were diagnosed with KOA that received ESWT were selected as the ESWT group. The treatment parameters were as follows, 2.0 bar, 0.25 mJ/mm, and 8 Hz/s (...) for twice a week for 4 weeks continuously. In addition, 104 patients receiving oral administration of nonsteroidal anti-inflammatory drugs (NSAIDs) from April 2015 to April 2016 were also selected as the NSAIDs group. At 4, 8, 12, and 16 weeks upon the completion of treatment, the Visual Analogue Scale (VAS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) were adopted to evaluate the changes in pain and function of patients in both groups. For the ESWT group, the 50-m quick walk

2019 Medicine

129. Effect of Increasing Blood Pressure With Noradrenaline on the Microcirculation of Patients With Septic Shock and Previous Arterial Hypertension. (Abstract)

; arterial hypertension: 16.4 ± 3.5 mm/mm to 19.1 ± 3 mm/mm; groups: p = 0.51; T0 and T1: p < 0.001; group and time interaction: p = 0.70), and microcirculatory flow index (control: 2.1 ± 0.6 to 2.4 ± 0.6; arterial hypertension: 2.1 ± 0.5 to 2.6 ± 0.2; groups: p = 0.71; T0 and T1: p = 0.002; group and time interaction: p = 0.45) in both groups.Increasing mean arterial pressure with noradrenaline in septic shock patients improves density and flow in small vessels of sublingual microcirculation. However (...) Effect of Increasing Blood Pressure With Noradrenaline on the Microcirculation of Patients With Septic Shock and Previous Arterial Hypertension. To assess whether an increase in mean arterial pressure in patients with septic shock and previous systemic arterial hypertension changes microcirculatory and systemic hemodynamic variables compared with patients without arterial hypertension (control).Prospective, nonblinded, interventional study.Three ICUs in two teaching hospitals.After informed

2019 Critical Care Medicine

130. Profile and Outcomes of Surgical Treatment for Ventricular Septal Rupture in Patients with Shock. (Abstract)

cardiogenic shock (67.6%) and 34 without cardiogenic shock (32.4%), who underwent surgical treatment in the Department of Adult Cardiac Surgery of Fuwai Hospital between January 2002 and December 2017. Baseline characteristics and outcomes in patients with ventricular septal rupture with and without cardiogenic shock were assessed.There were no differences in hypertension, diabetes, history of myocardial infarction, body mass index, or location of ventricular septal rupture between patients (...) Profile and Outcomes of Surgical Treatment for Ventricular Septal Rupture in Patients with Shock. The outcomes of surgical treatment of ventricular septal rupture complicating acute myocardial infarction are worse in patients with cardiogenic shock.This study aimed to identify clinical characteristics and outcomes in patients with ventricular septal rupture presenting with cardiogenic shock.A retrospective analysis was performed in 105 consecutive ventricular septal rupture patients, 71with

2019 Annals of Thoracic Surgery

131. Utilization and Outcomes of Temporary Mechanical Circulatory Support Devices in Cardiogenic Shock. (Abstract)

Utilization and Outcomes of Temporary Mechanical Circulatory Support Devices in Cardiogenic Shock. Cardiogenic shock (CS) is associated with high morbidity and mortality despite recent advances in the temporary mechanical circulatory support (MCS) devices. The current utilization and outcomes of these MCS devices with or without vasopressors compared with conventional medical therapy (no-MCS) in CS remain poorly described. The study population was extracted from the 2014 Nationwide Readmissions (...) Database using International Classification of Diseases, Ninth Revision, Clinical Modification codes for CS, temporary MCS devices, and vasopressor infusion. Study end points included in-hospital all-cause mortality, length of index hospital stay (LOS), the likelihood of receiving invasive treatment, postprocedural bleeding, vascular complications, total hospitalization charges, and discharge disposition. A total of 59,148 discharges with a diagnosis of CS were identified (age 67 years; 38.5% female

2019 American Journal of Cardiology

132. The Effects Of Extracorporeal Shock Wave Therapy On Pain, Disability And Life Quality Of Chronic Low Back Pain Patients. (Abstract)

The Effects Of Extracorporeal Shock Wave Therapy On Pain, Disability And Life Quality Of Chronic Low Back Pain Patients. Low back pain is the most common form of pain related to the musculoskeletal system disorders. ESWT has been suggested as a new treatment modality in CLBP and its effectiveness has been investigated in a small number of studies.The aim of this study is to investigate the effect of Extracorporeal Shockwave Therapy (ESWT) on pain, functional status, and quality of life compared (...) (NRS), Oswestry Disability Index (ODI), Hospital Anxiety and Depression Scale (HADS), Short-form 36 (SF-36). The data were obtained before treatment (W0), at sixth (W6) and twelfth week (W12).In Group 1, statistically significant improvement was found in all parameters of rest and movement NRS, ODI, HADS and SF-36 except for emotional role at both W6 and W12 compared to W0(P < .05). Comparison of the difference scores of the two groups showed significantly superior improvement in Group 1 for all

2019 Alternative Therapies in Health & Medicine Controlled trial quality: uncertain

133. Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study. Full Text available with Trip Pro

Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study. Supraventricular arrhythmias contribute to haemodynamic compromise in septic shock. A retrospective study generated the hypothesis that propafenone could be more effective than amiodarone in achieving and maintaining sinus rhythm (SR). Certain echocardiographic parameters may predict a successful (...) cardioversion and help in the decision on rhythm or rate control strategy.The trial includes septic shock patients with new-onset arrhythmia, but without severe impairment of the left ventricular ejection fraction. After baseline echocardiography, the patient is randomised to receive a bolus and maintenance dose of either amiodarone or propafenone. The primary outcome is the proportion of patients that have achieved rhythm control at 24 hours after the start of the infusion. The secondary outcomes

2019 BMJ open Controlled trial quality: predicted high

134. Assessing and managing hypovolemic shock in puerperal women. (Abstract)

in pregnancy. The Shock Index [SI] is one composite vital sign that may help in the identification of women with hypovolemic shock. Values of SI ≥ 1 in the first hour postpartum indicate cardiac decompensation, and treatment should be implemented immediately. From the diagnosis of PPH, first-line measures should ensure coordinated care actions including the availability of blood derivatives, the establishment of conditions for volume replacement, oxygen therapy, and identification and timely treatment (...) Assessing and managing hypovolemic shock in puerperal women. The major cause of maternal death worldwide is postpartum hemorrhage (PPH). Early identification is the basis for adequate treatment. In addition to the visual estimation of blood loss, clinical signs could offer a more reliable representation of the cardiovascular system of the bleeding woman. However, in postpartum women, recognition of hypovolemic shock through vital signs is impaired owing to physiological cardiovascular changes

2019 Best practice & research. Clinical obstetrics & gynaecology

135. Effect of JJ stent on outcomes of extracorporeal shock wave lithotripsy treatment of moderate sized renal pelvic stones: A randomized prospective study. (Abstract)

Effect of JJ stent on outcomes of extracorporeal shock wave lithotripsy treatment of moderate sized renal pelvic stones: A randomized prospective study. To evaluate the effect of JJ stents on SWL treatment of moderate (15-25mm) renal pelvic stones.Between January 2016 and December 2017, a total of 152 adult patients who were planned to undergo SWL for a single radiopaque renal pelvic stone were included in the study. Patients with solitary kidney, congenital abnormality, skeletal tract (...) difference in terms of age, sex, body mass index, renal parancyhimal thickness, hydronephrosis, skin-to-stone distance, Hounsfield units, and stone size between the groups. Success was significantly higher in the stented group than in the non-stented group (71% vs. 39%, P=.002). In stone-free patients, the number of emergency department visits and analgesic tablet consumption was significantly lower in the stented group than in the non-stented group (P<.001 and P<.001, respectively). In non- stone-free

2019 Actas urologicas espanolas Controlled trial quality: uncertain

136. The effects of shock wave and dry needling on active trigger points of upper trapezius muscle in patients with non-specific neck pain: A randomized clinical trial. (Abstract)

The effects of shock wave and dry needling on active trigger points of upper trapezius muscle in patients with non-specific neck pain: A randomized clinical trial. Chronic neck pain is associated with various myofascial trigger points (MTrPs).A single-blind randomized clinical trial was designed to compare the effects of extracorporeal shock wave therapy (ESWT) with dry needling (DN) techniques on the upper trapezius muscle trigger point in patients with non-specific neck pain (NSNP).Seventy (...) patients with NSNP and active MTrPs of the upper trapezius muscle were randomly divided into two groups: an ESWT group (n= 35) and a DN group (n= 35). Treatment sessions were performed for three weeks and all participants received related intervention once a week. The outcome measures were pain intensity, measured by a numeric pain rating scale (NPRS), pain pressure threshold (PPT), measured with a digital algometer, and functional disability, evaluated by using the neck disability index (NDI).NPRS

2019 Journal of back and musculoskeletal rehabilitation Controlled trial quality: uncertain

137. The effect of cardiac shock wave therapy on myocardial function and perfusion in the randomized, triple-blind, sham-procedure controlled study. Full Text available with Trip Pro

The effect of cardiac shock wave therapy on myocardial function and perfusion in the randomized, triple-blind, sham-procedure controlled study. Recent triple-blind sham procedure-controlled study revealed neutral effects of the cardiac shock wave therapy (CSWT) on exercise tolerance and symptoms in patients with stable angina. Current data about the effects of CSWT on global and regional myocardial contractility and perfusion is limited. Hereby we report the results of an imaging sub-study (...) ischemia tests were performed in 59 study patients: DSE and SPECT before the CSWT treatment and after 6 months, with DSE carried out additionally at 3 months after randomization. Co-primary endpoints of the study were: change in wall motion score index (WMSI), representing the stress-induced impairment of regional myocardial function, and change in summed difference score (SDS), representing the amount of perfusion defect.OMT + CSWT and OMT + sham procedure study groups included 30 and 29 patients

2019 Cardiovascular ultrasound Controlled trial quality: uncertain

138. Comparison of extracorporeal shock wave therapy with custom foot orthotics in plantar fasciitis treatment: A prospective randomized one-year follow-up study. (Abstract)

Comparison of extracorporeal shock wave therapy with custom foot orthotics in plantar fasciitis treatment: A prospective randomized one-year follow-up study. Plantar fasciitis (PF) is characterized by the degeneration of the plantar fascia, leading to heel pain. We aimed to investigate the effectiveness of extracorporeal shock wave therapy (ESWT) and custom foot orthotics (CFO).The study was planned as a prospective randomized controlled study. In total, 83 patients were evaluated. The patients (...) were divided into two groups: patients treated with ESWT (group I, n=40) and patients treated with CFO (group II, n=43). Visual analogue scale (VAS) was used to evaluate pain in the morning, evening, at rest and while walking. Foot Function Index (FFI) was used to evaluate foot functions, and Foot Health Status Questionnaire (FHSQ) was used to evaluate foot health.Both group I and group II achieved significant improvements in our evaluation parameters (morning and evening pain) at 4, 12 and 24

2019 Journal of musculoskeletal & neuronal interactions Controlled trial quality: uncertain

139. [Effects of different target blood pressure resuscitation on peripheral blood inflammatory factors and hemodynamics in patients with traumatic hemorrhagic shock]. (Abstract)

[Effects of different target blood pressure resuscitation on peripheral blood inflammatory factors and hemodynamics in patients with traumatic hemorrhagic shock]. To investigate the target blood pressure level of restrictive fluid resuscitation in patients with traumatic hemorrhagic shock.Sixty patients with traumatic hemorrhagic shock admitted to the First Affiliated Hospital of Bengbu Medical College from January 2016 to December 2018 were enrolled. All patients were resuscitated with sodium (...) the three groups. Three groups of patients were resuscitated for 30 minutes to achieve the target blood pressure level and maintain 30 minutes. With the prolongation of fluid resuscitation time, the central venous pressure (CVP), cardiac output (CO) and cardiac index (CI) were increased slowly in the three groups, and reached a steady state at about 30 minutes after resuscitation, especially in the high MAP group and the middle MAP group. The expressions of serum inflammatory factors in the three groups

2019 Zhonghua wei zhong bing ji jiu yi xue Controlled trial quality: uncertain

140. Comments on GEDI vs. CVP goal-directed fluid resuscitation for chronic obstructive pulmonary disease patients with septic shock: A randomized controlled trial. (Abstract)

University of Chinese Medicine, Guangzhou, 510120, Guangdong Province, China.. Electronic address: 3021376873@qq.com. eng Letter 2019 03 11 United States Am J Emerg Med 8309942 0735-6757 IM Central venous pressure (CVP) Chronic obstructive pulmonary disease (COPD) Fluid resuscitation Global end-diastolic volume index (GEDI) Septic shock 2019 03 03 2019 03 11 2019 3 31 6 0 2019 3 31 6 0 2019 3 31 6 0 ppublish 30926228 S0735-6757(19)30168-8 10.1016/j.ajem.2019.03.019 (...) Comments on GEDI vs. CVP goal-directed fluid resuscitation for chronic obstructive pulmonary disease patients with septic shock: A randomized controlled trial. 30926228 2019 08 26 1532-8171 37 9 2019 Sep The American journal of emergency medicine Am J Emerg Med Comments on GEDI vs. CVP goal-directed fluid resuscitation for chronic obstructive pulmonary disease patients with septic shock: A randomized controlled trial. 1803-1804 S0735-6757(19)30168-8 10.1016/j.ajem.2019.03.019 Cai Hairong H

2019 The American journal of emergency medicine Controlled trial quality: predicted high

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