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Sexual Development

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1. The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development (...) The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: systematic and realist reviews and intervention development Flowers P, Wu O, Lorimer K, Ahmed B, Hesselgreaves H, MacDonald J, Cayless S, Hutchinson S, Elliott L, Sullivan A, Clutterbuck D, Rayment M & McDaid L Citation Flowers P, Wu O, Lorimer K, Ahmed B, Hesselgreaves H, MacDonald J, Cayless S, Hutchinson S, Elliott L

2017 Health Technology Assessment (HTA) Database.

2. Buffer or Brake? The Role of Sexuality-Specific Parenting in Adolescents’ Sexualized Media Consumption and Sexual Development (PubMed)

Buffer or Brake? The Role of Sexuality-Specific Parenting in Adolescents’ Sexualized Media Consumption and Sexual Development One main source of sexual socialization lies within family interactions. Especially sexuality-specific parenting may determine adolescents' sexual development-adolescents' sexual behavior and sexual risk behavior, sexualized media consumption and permissive sexual attitudes-to a significant extent, but different ideas exist about how this works. In this longitudinal (...) study, we examined two hypotheses on how sexuality-specific parenting-parenting aimed specifically at children's sexual attitudes and behaviors-relates to adolescents' sexual development. A first buffer hypothesis states that parents' instructive media discussions with their children-called instructive mediation-buffers the effect of sexualized media consumption on adolescents' sexual attitudes and behavior and, vice versa, the effect of adolescents' sexual attitudes and behavior on sexualized media

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2018 Journal of youth and adolescence

3. The Sexual Event Diary (SED): Development and Validation of a Standardized Questionnaire for Assessing Female Sexual Functioning During Discrete Sexual Events. (PubMed)

The Sexual Event Diary (SED): Development and Validation of a Standardized Questionnaire for Assessing Female Sexual Functioning During Discrete Sexual Events. The efficacy of on-demand drugs for hypoactive sexual desire disorder (HSDD) or female sexual interest/arousal disorder (FSIAD) should be assessed using a validated instrument that assesses the discrete sexual events during which the on-demand drug is taken.To develop and validate an event log for measuring sexual satisfaction and sexual (...) demonstrating the ability to detect change.The SED is a good tool for assessing sexual function during a discrete sexual event and for assessing the sexual function of women over longer periods.The validation of the SED was performed on data from nearly 11,000 sexual events, gathered as part of a drug development program for HSDD and FSIAD. This amount of data provides very robust results when related to drug use for HSDD and FSIAD, but caution is advised when generalizing the validity of the SED directly

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2017 Journal Of Sexual Medicine

4. Sexual system, reproductive cycle and embryonic development of the red-striped shrimp Lysmata vittata, an invader in the western Atlantic Ocean. (PubMed)

Sexual system, reproductive cycle and embryonic development of the red-striped shrimp Lysmata vittata, an invader in the western Atlantic Ocean. Several decapod crustaceans are invaders, but little is known about the biological characteristics that potentiate the success of these decapods in invaded ecosystems. Here, we evaluate and describe some aspects of the reproductive biology and development of Lysmata vittata, an invasive shrimp species in the Atlantic Ocean. In addition, we intend (...) to provide important insights into the biology of invasion by comparing the reproductive traits of this shrimp with some of the predictions about aquatic invasive species. We used experimental and laboratory observations to evaluate the functionality of protandric simultaneous hermaphroditism (PSH), the macro and microscopic development of the ovarian portion of the ovotestes, the reproductive cycle, and the embryonic development of L. vittata. We confirm the functionality of PSH in L. vittata

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2019 PLoS ONE

5. Generation of a sexually mature individual of the Eastern dwarf tree frog, Litoria fallax, from cryopreserved testicular macerates: proof of capacity of cryopreserved sperm derived offspring to complete development (PubMed)

Generation of a sexually mature individual of the Eastern dwarf tree frog, Litoria fallax, from cryopreserved testicular macerates: proof of capacity of cryopreserved sperm derived offspring to complete development Amphibians are the most threatened vertebrate class globally based on recent rates of decline and extinction. Sperm cryopreservation and other assisted reproductive technologies have the potential to help manage small and threatened populations and prevent extinctions (...) . There are a growing number of reports of recovery of amphibian sperm after cryopreservation, but relatively few published reports of amphibian embryos generated from frozen sperm developing beyond metamorphosis to the adult stage and achieving sexual maturation. In this study on the Eastern dwarf tree frog (Litoria fallax), a temperate amphibian species from eastern Australia, a small number of viable metamorphs and one sexually mature male frog (itself producing sperm) were produced from cryopreserved sperm

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2018 Conservation physiology

6. Ontogenetic development of gonads and external sexual characters of the protandric simultaneous hermaphrodite peppermint shrimp, Lysmata vittata (Caridea: Hippolytidae). (PubMed)

Ontogenetic development of gonads and external sexual characters of the protandric simultaneous hermaphrodite peppermint shrimp, Lysmata vittata (Caridea: Hippolytidae). The peppermint shrimp Lysmata vittata (Caridea: Hippolytidae) is a marine caridean shrimp popular in marine aquarium trade. The species is known to display the sexual system of protandric simultaneous hermaphrodite. In this study, based on captive bred specimens, the complete ontogenetic gonad development of L. vittata (...) and the ovarian part were mature and hence is defined as euhermaphrodite phase. At the euhermaphrodite phase, most individuals lacked cincinulli and appendices masculinae on the first and second pair of pleopods respectively. This is the first time that complete ontogenetic gonadal and external sexual character development have been described and staged for a species from the genus Lysmata from newly settled juveniles to euhermaphrodite phase.

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2019 PLoS ONE

7. HMGB proteins are required for sexual development in Aspergillus nidulans. (PubMed)

HMGB proteins are required for sexual development in Aspergillus nidulans. Aspergillus nidulans has three high mobility group box (HMGB) proteins, HmbA, HmbB and HmbC that are chromatin-associated architectural proteins involved in DNA-related functions. By creating and studying deletion strains in both veA+ and veA1 background, we have characterized the role of HmbA, HmbB and HmbC in sexual development. Expression of the mating-type MAT1-1 and MAT1-2 coding genes were found to be extremely (...) down-regulated in all three mutants on day 4 of sexual development, which results in deficient ascospore production and/or ascospore viability in the mutants. In addition, we found that HmbA and HmbB play also a role in sensing of and response to environmental signals, while HmbC functionally interacts with VeA, a key regulator of the coordination of asexual and sexual development, as well as of secondary metabolism.

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2019 PLoS ONE

8. The Rectal Cancer Female Sexuality Score: Development and Validation of a Scoring System for Female Sexual Function After Rectal Cancer Surgery. (PubMed)

The Rectal Cancer Female Sexuality Score: Development and Validation of a Scoring System for Female Sexual Function After Rectal Cancer Surgery. Sexual dysfunction and impaired quality of life is a potential side effect to rectal cancer treatment.The objective of this study was to develop and validate a simple scoring system intended to evaluate sexual function in women treated for rectal cancer.This is a population-based cross-sectional study.Female patients diagnosed with rectal cancer (...) between 2001 and 2014 were identified by using the Danish Colorectal Cancer Group's database. Participants filled in the validated Sexual Function Vaginal Changes questionnaire. Women declared to be sexually active at follow-up were randomly assigned to 2 groups: one for development and one for validation. Logistic regression analyses identified items for the score, and multivariate analysis established a weighted-score value allocated to each item, adding up to the total score. The validity

2018 Diseases of the Colon & Rectum

9. Randomised controlled trial: Prime time youth development intervention improves contraceptive use and sexual awareness among sexually active adolescent girls

Randomised controlled trial: Prime time youth development intervention improves contraceptive use and sexual awareness among sexually active adolescent girls Prime time youth development intervention improves contraceptive use and sexual awareness among sexually active adolescent girls | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Prime time youth development intervention improves contraceptive use and sexual awareness among sexually

2014 Evidence-Based Nursing

10. The Development of the Genital Psoriasis Sexual Frequency Questionnaire (GenPs-SFQ) to Assess the Impact of Genital Psoriasis on Sexual Health (PubMed)

The Development of the Genital Psoriasis Sexual Frequency Questionnaire (GenPs-SFQ) to Assess the Impact of Genital Psoriasis on Sexual Health Patient-reported outcome measures (PROs) exist for psoriasis but not genital psoriasis (GenPs).This cross-sectional, qualitative study in patients with moderate-to-severe GenPs was conducted to support development of a PRO for measuring the impact of GenPs on sexual activity and to establish content validity. The impacts of GenPs were identified (...) upon by two clinicians who routinely care for patients with GenPs. Interviews were then conducted with GenPs patients (n = 20) to discuss the impact of GenPs on their HRQoL. Eighty percent of patients reported that GenPs impacted sexual frequency. The two-item GenPs Sexual Frequency Questionnaire (GenPs-SFQ) was developed to assess limitations on sexual activity frequency because of GenPs. Cognitive debriefing with an additional 50 patients with GenPs confirmed the utility and understandability

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2017 Dermatology and therapy

11. Development and Refinement of a Targeted Sexual Risk Reduction Intervention for Women With a History of Childhood Sexual Abuse (PubMed)

Development and Refinement of a Targeted Sexual Risk Reduction Intervention for Women With a History of Childhood Sexual Abuse Childhood sexual abuse (CSA) is associated with sexual risk behavior in adulthood. Traditional sexual risk reduction interventions do not meet the unique needs of women who have been sexually abused. In the current paper, we describe the four-stage process we followed to develop and refine a targeted sexual risk reduction intervention for this population. First, initial (...) on the qualitative and quantitative results, we developed a 5-session, group-delivered intervention to address the maladaptive thoughts that occurred as a result of CSA, as well as the cognitive-behavioral determinants of sexual risk behavior. This intervention drew heavily on cognitive behavioral techniques to address cognitions associated with CSA and the links between these cognitions and current sexual risk behavior. Techniques from trauma-based therapies, as well as motivational techniques, were also

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2017 Cognitive And Behavioral Practice

12. Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have sex with men

of depression, anxiety, mood or mental disorders, eating disorders, suicidality, and drug and alcohol use (2;7-9). A history of childhood sexual abuse may affect antiretroviral adherence in men who have sex with men (1). Very few interventions have been developed to address the traumatic stress of childhood sexual abuse on HIV transmission risk. Of those, a stress-focused intervention and a cognitive behaviour health intervention seemed to be effective in reducing sexual risk behaviours among HIV-positive (...) studies specifically looked at the relationship between childhood sexual abuse and eating disorders: Among 383 men who have sex with men in Toronto, those who had a reported history of childhood sexual abuse were twice as likely to develop symptoms of disordered eating (9). In a study of 193 men who have sex with men in New York City, those with a history of childhood sexual abuse were significantly more likely to have subclinical eating disorders than men with no history of childhood sexual abuse

2016 Ontario HIV Treatment Network

13. Transcriptomic and proteomic analysis reveals wall-associated and glucan-degrading proteins with potential roles in Phytophthora infestans sexual spore development. (PubMed)

Transcriptomic and proteomic analysis reveals wall-associated and glucan-degrading proteins with potential roles in Phytophthora infestans sexual spore development. Sexual reproduction remains an understudied feature of oomycete biology. To expand our knowledge of this process, we used RNA-seq and quantitative proteomics to examine matings in Phytophthora infestans. Exhibiting significant changes in mRNA abundance in three matings between different A1 and A2 strains compared to nonmating (...) controls were 1170 genes, most being mating-induced. Rising by >10-fold in at least one cross were 455 genes, and 182 in all three crosses. Most genes had elevated expression in a self-fertile strain. Many mating-induced genes were associated with cell wall biosynthesis, which may relate to forming the thick-walled sexual spore (oospore). Several gene families were induced during mating including one encoding histidine, serine, and tyrosine-rich putative wall proteins, and another encoding prolyl

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2018 PLoS ONE

14. Developing a culturally appropriate illustrated tool for the self-collection of anorectal specimens for the testing of sexually transmitted infections: lessons from Papua New Guinea. (PubMed)

Developing a culturally appropriate illustrated tool for the self-collection of anorectal specimens for the testing of sexually transmitted infections: lessons from Papua New Guinea. Papua New Guinea (PNG) has a high prevalence of sexually transmitted infections (STIs). There is increasing evidence that anorectal STIs are important in terms of the dual epidemics of HIV and STIs in this setting. At the time of this study, anorectal STI testing was not possible, and there was no mechanism (...) and provided critical feedback for the adaption of a previously piloted and published pictorial anorectal specimen collection tool for use with key populations in PNG.The final instruction tools are presented in English language and Tok Pisin. To develop these, participants feedback resulted in six key areas of the existing instruction document being modified to ensure it was appropriate for use in PNG. These included translating complex words for sexual health issues (i.e. 'STIs', 'anorectal STIs', 'anus

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2019 BMC Public Health

15. Developing a Mobile App (LYNX) to Support Linkage to HIV/Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis for Young Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial. (PubMed)

Developing a Mobile App (LYNX) to Support Linkage to HIV/Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis for Young Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial. Young men who have sex with men (YMSM) in the United States have among the highest incidence of HIV and sexually transmitted infection (STI) and the lowest uptake of HIV and STI testing and pre-exposure prophylaxis (PrEP). Nearly universal mobile phone ownership among youth provides (...) the LYNX app; an open technical pilot among 15 YMSM to optimize usability of the app; and then a 6-month pilot RCT among 60 HIV-uninfected YMSM at risk for HIV acquisition. Developed using the Information, Motivation, and Behavioral skills theoretical model, the LYNX app includes an electronic diary to track sexual behaviors (information), a personalized risk score to promote accurate risk perception (information/motivation), testing reminders (motivation/behavioral skills), and access to home-based

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2019 JMIR Research Protocols

16. Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana. (PubMed)

Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana. It is well established that steroid hormones regulate sexual behavior in vertebrates via organizational and activational effects. However, whether the organizational/activational paradigm applies more broadly to the sexual behavior of other animals such as insects is not well established. Here we describe the hormonal regulation of a sexual behavior in the seasonally (...) polyphenic butterfly Bicyclus anynana is consistent with the characteristics of an organizational effect. By measuring hormone titer levels, quantifying hormone receptor gene expression in the brain, and performing hormone manipulations, we demonstrate steroid hormone signaling early in pupal development has a latent effect on adult male sexual behavior in B. anynana. These findings suggest the organizational/activational paradigm may be more highly conserved across animal taxa than previously thought.

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2017 PLoS ONE

17. Sexually transmitted infections: condom distribution schemes

People who use or are considering using condom distribution schemes, their families and carers, and the general public NICE worked with Public Health England to develop this guidance. Sexually transmitted infections: condom distribution schemes (NG68) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 29Recommendations Recommendations Making decisions using NICE guidelines explains how we use words to show (...) was developed, including details of the committee. Sexually transmitted infections: condom distribution schemes (NG68) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 14 of 29The committee The committee's discussion 's discussion Evidence statement numbers are given in square brackets. For an explanation of the evidence statement numbering, see the evidence reviews section. Background This guideline supplements existing

2017 National Institute for Health and Clinical Excellence - Clinical Guidelines

18. Effects of bystander programs on the prevention of sexual assault among adolescents and college students: a systematic review

was developed and popularized in the US but has been adapted for use in global contexts. How the intervention might work By treating young people as potential allies in preventing sexual assault, bystander programs have the potential to be less threatening than traditional sexual assault prevention programs, which tend to approach young people as either potential perpetrators or victims of sexual violence (Burn, 2009; Messner, 2015; [Jackson] Katz, 1995). Instead of placing emphasis on how young people may (...) , & Tharp, 2015; Harned, 2001; Howard, Wang, & Yan, 2007). Thus, the earliest bystander programs tended to apply a gendered perspective to the prevention of sexual assault among adolescents and college students. For example, Katz (1995) developed MVP with the goal of inspiring male college athletes to challenge sociocultural definitions of masculinity that equate men’s strength with dominance over women. At the time of its inception, MVP was unique in its explicit focus on masculinity as well as its

2019 Campbell Collaboration

19. Sexualized drug use (chemsex and methamphetamine) and men who have sex with men

, 2019. Bourne A, Weatherburn P. Substance use among men who have sex with men: Patterns, motivations, impacts and intervention development need. Sexually Transmitted Infections. 2017;93(5):342–6. Edmundson C, Heinsbroek E, Glass R, Hope V, Mohammed H, White M, et al. Sexualised drug use in the United Kingdom (UK): A review of the literature. International Journal of Drug Policy. 2018;55:131–48. Melendez-Torres GJ, Bourne A. Illicit drug use and its association with sexual risk behaviour among MSM (...) Sexualized drug use (chemsex and methamphetamine) and men who have sex with men Sexualized drug use (chemsex and methamphetamine) and men who have sex with men | The Ontario HIV Treatment Network The Ontario HIV Treatment Network Sexualized drug use (chemsex and methamphetamine) and men who have sex with men Sexualized drug use (chemsex and methamphetamine) and men who have sex with men , , , , , , , , , , Questions What is the impact of sexualized drug use (specifically of chemsex

2019 Ontario HIV Treatment Network

20. Measuring Sexual Minority Stressors in Lesbian Women's Daily Lives: Initial Scale Development. (PubMed)

Measuring Sexual Minority Stressors in Lesbian Women's Daily Lives: Initial Scale Development. Lesbian women face unique sexual minority stressors (SMS) due to their stigmatized and marginalized status in society. Existing studies of SMS are primarily cross-sectional and use global measures of SMS. The goal of the present study was to develop a brief daily measure of SMS for use in daily diary or ecological momentary assessment (EMA) studies. Existing retrospective measures of SMS were reviewed

2018 Psychology of sexual orientation and gender diversity

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