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Serum Magnesium

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41. Serum magnesium, phosphorus, and calcium levels and subclinical calcific aortic valve disease: A population-based study. Full Text available with Trip Pro

Serum magnesium, phosphorus, and calcium levels and subclinical calcific aortic valve disease: A population-based study. Calcific aortic valve disease (CAVD) is the most common valve disease. Although micronutrients are known to contribute to cardiovascular disease, the relationship with CAVD remains poorly evaluated. We examined the association of serum levels of magnesium, phosphorus, and calcium with prevalence, incidence, and progression of aortic valve calcification (AVC).We conducted (...) , behaviors and cardiovascular risk factors, relative risks (95% confidence intervals) in the highest versus lowest categories of serum magnesium, phosphorus, and calcium were 0.62 (0.44-0.86), 1.45 (1.02-2.04), and 1.43 (0.95-2.15), respectively, for AVC prevalence and 0.62 (0.42-0.92), 1.93 (1.28-2.91), and 1.09 (0.77-1.55), respectively, for AVC incidence. Their linear trends of serum magnesium and phosphorus were also all statistically significant. Of 131 participants with baseline AVC

2018 Atherosclerosis

42. Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy

Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Serum Magnesium Level Administration in Severe Pre-eclampsia Obese Pregnancy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03661775 Recruitment Status : Not yet recruiting First Posted : September 7, 2018 Last Update

2018 Clinical Trials

43. The prevalence of serum magnesium and iron deficiency anaemia among Sudanese women in early pregnancy: a cross-sectional study. (Abstract)

The prevalence of serum magnesium and iron deficiency anaemia among Sudanese women in early pregnancy: a cross-sectional study. Anaemia during pregnancy is associated with adverse maternal and child health. Investigations of anaemia and its predictors among pregnant women are needed for preventive measures.A cross-sectional study was conducted to investigate the prevalence and determinants of anaemia in early pregnancy in Khartoum, Sudan. Clinical characteristics were gathered using (...) a questionnaire. Serum ferritin, magnesium and high-sensitivity C-reactive protein (hs-CRP) were measured using different laboratory methods.Of the 180 women in the study, 65.0% had anaemia (haemoglobin [Hb] <11 g/dl), 0.6% had severe anaemia (Hb <7 g/dl), 38.9% had iron deficiency (serum ferritin <15 μg/l), 30.6% had iron deficiency anaemia (<11 g/dl and serum ferritin <15 μg/l) and 57.2% had magnesium deficiency (<1.80 mg/dl). There was no significant difference in the age, parity, gestational age, body

2018 Transactions of the Royal Society of Tropical Medicine & Hygiene

44. Association of admission serum levels of vitamin D, calcium, Phosphate, magnesium and parathormone with clinical outcomes in neurosurgical ICU patients Full Text available with Trip Pro

Association of admission serum levels of vitamin D, calcium, Phosphate, magnesium and parathormone with clinical outcomes in neurosurgical ICU patients To evaluate the association of admission serum levels of 25(OH)D, parathormone and the related electrolytes with severity of illness and clinical outcomes in neurosurgical critically ill patients, serum levels of 25(OH)D, parathormone, calcium, magnesium, and phosphate, along with APACHE II score were measured for 210 patients upon admission (...) that among all clinical outcomes, admission hypovitaminosis D was associated with longer duration of ICU stay and a high admission of parathormone was associated with in ICU mortality. We concluded that disorders of admission serum levels of 25(OH)D, parathormone, calcium, magnesium, and phosphate are related to the presence of multiple causal factors such as severity of disease and are not independently associated with clinical outcomes. Most often they are normalize spontaneously with resolution

2018 Scientific reports

45. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients Full Text available with Trip Pro

Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients Population-based studies have revealed a high prevalence of cognitive impairment after stroke. We aimed to determine the impact of serum magnesium (Mg2+) levels on the occurrence of poststroke cognitive impairment (PSCI).Acute ischemic stroke patients (n = 327) were enrolled in our study and serum Mg2+ levels were assessed on admission. The cognitive performance of each patient (...) was evaluated using the Mini-Mental State Examination (MMSE) at a 1-month follow-up visit.One hundred five (32.1%) patients were diagnosed with PSCI at 1-month poststroke. The serum Mg2+ levels in both the PSCI group and the non-PSCI group were significantly lower than those in normal control group (P<0.001). In addition, the PSCI group had lower levels of serum Mg2+ compared to the non-PSCI group (P=0.003). In the binary logistic regression analysis, a serum Mg2+ level of ≤0.82 mmol/L was significantly

2018 Neuropsychiatric disease and treatment

46. Effects of magnesium citrate, magnesium oxide and magnesium sulfate supplementation on arterial stiffness in healthy overweight individuals: a study protocol for a randomized controlled trial. Full Text available with Trip Pro

. It remained unclear whether the observed effect was due to magnesium or citrate, and whether other magnesium compounds may have similar effects. Therefore, we aim to study the long-term effects of magnesium citrate, magnesium oxide and magnesium sulfate on arterial stiffness. In addition, we aim to investigate possible underlying mechanisms, including changes in blood pressure and changes in gut microbiota diversity.In this randomized, double-blind, placebo-controlled trial, a total of 162 healthy (...) overweight and slightly obese men and women will be recruited. During a 24-week intervention, individuals will be randomized to receive: magnesium citrate; magnesium oxide; magnesium sulfate (total daily dose of magnesium for each active treatment 450 mg); or placebo. The primary outcome of the study is arterial stiffness measured by the carotid-femoral pulse wave velocity (PWVc-f), which is the gold standard for quantifying arterial stiffness. Secondary outcomes are office blood pressure, measured

2019 Trials Controlled trial quality: predicted high

47. Assessment of magnesium deficiency

(approximately 19%). Hypomagnesaemia (low serum magnesium concentration) is generally defined as serum magnesium <0.9 mmol/L (<1.8 mEq/L). However, only 1% of magnesium is found in the extracellular fluid, so the serum magnesium level is a poor indicator of the total magnesium content and availability in the body. There is no simple, rapid, and accurate laboratory test to determine total body magnesium status in humans. Franz KB. A functional biological marker is needed for diagnosing magnesium deficiency. J (...) (low serum magnesium concentration) Patients with hypomagnesaemia (low serum magnesium concentration) in the absence of magnesium deficiency (i.e., a normal total body magnesium content) Patients with magnesium deficiency (low total body magnesium content) but no evidence of hypomagnesaemia (i.e., a normal serum magnesium concentration). Magnesium homoeostasis About 60% of magnesium in the serum is free, whereas approximately 33% is bound to proteins, and <7% is bound to citrate, bicarbonate, ATP

2018 BMJ Best Practice

48. Magnesium

the effect of magnesium supplementation on the depression status of depressed patients suffering from magnesium deficiency. Sixty depressed people suffering from hypomagnesemia participated in this trial. The individuals were randomly categorized into two groups of 30 members; one receiving two 250-mg tablets of magnesium oxide (MG) daily and the other receiving placebo (PG) for 8 wk. The Beck Depression Inventory-II was conducted and the concentration of serum magnesium 2017 Follow us: © 2019 Trip (...) Magnesium Top results for magnesium - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Latest and Greatest

49. Magnesium Supplementation and Blood Pressure Reduction

Magnesium Supplementation and Blood Pressure Reduction Magnesium Supplementation and Blood Pressure Reduction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Magnesium Supplementation and Blood Pressure (...) Collaborator: Pure Encapsulations Information provided by (Responsible Party): Howard D. Sesso, ScD, MPH, Brigham and Women's Hospital Study Details Study Description Go to Brief Summary: This double-blind, placebo-controlled randomized clinical trial will test whether a magnesium glycinate supplement (480 mg/day) taken for 12 weeks lowers blood pressure. Condition or disease Intervention/treatment Phase Blood Pressure Dietary Supplement: magnesium glycinate supplement Dietary Supplement: placebo

2018 Clinical Trials

50. Correction to: The effect of acute vs chronic magnesium supplementation on exercise and recovery on resistance exercise, blood pressure and total peripheral resistance on normotensive adults Full Text available with Trip Pro

Correction to: The effect of acute vs chronic magnesium supplementation on exercise and recovery on resistance exercise, blood pressure and total peripheral resistance on normotensive adults The original article [1] contains an error whereby the datum value of '17.7%' in both the Abstract and the first line of the Bench press sub-section of the Results section is incorrect.

2018 Journal of the International Society of Sports Nutrition

51. Changes of Blood Pressure and Hemodynamic Parameters after Oral Magnesium Supplementation in Patients with Essential Hypertension—An Intervention Study Full Text available with Trip Pro

Changes of Blood Pressure and Hemodynamic Parameters after Oral Magnesium Supplementation in Patients with Essential Hypertension—An Intervention Study The objective of this study was to examine the changes of blood pressure and hemodynamic parameters after oral magnesium supplementation in patients with essential hypertension. The single-arm non-blinded intervention study comprised 48 patients (19 men; 29 women) whose antihypertensive therapy was not changed for at least one month (...) . The participants were asked to consume (daily at home) 300 mg of oral magnesium-oxide supplementation product for one month and to have their blood pressure and hemodynamic parameters (thoracic fluid content, stroke volume, stroke index, cardiac output, cardiac index, acceleration index, left cardiac work index and systemic vascular resistance index, heart rate) measured in the hospital before and after the intervention. Measurements were performed with impedance cardiography. After magnesium supplementation

2018 Nutrients

52. Magnesium Supplementation and Blood Pressure in Pregnancy: A Double-Blind Randomized Multicenter Study Full Text available with Trip Pro

Magnesium Supplementation and Blood Pressure in Pregnancy: A Double-Blind Randomized Multicenter Study To investigate the effect of magnesium (Mg) supplementation in healthy pregnant women for prevention of blood pressure increase. Secondary outcomes were comparison of biomarkers for hypertensive disorders and labour and fetal outcomes between the groups.Two hundred nulliparous healthy pregnant women were double-blind randomized to receive Mg daily or placebo.There were no differences in blood (...) pressure increase. However, among the Mg-treated women, there was a significant negative correlation between increase in blood levels of magnesium and increase in systolic blood pressure (p = 0.042). Magnesium supplementation seems to be safe for both mother and infant.Magnesium supplementation in healthy first-time pregnant women is not to be recommended for prevention of blood pressure increase. Supplementation in risk pregnancies needs to be further investigated. The study is listed on the ISRCTN

2018 Journal of pregnancy Controlled trial quality: uncertain

53. Magnesium and Intraoperative Blood Loss in Meningioma Surgery

Magnesium and Intraoperative Blood Loss in Meningioma Surgery Magnesium and Intraoperative Blood Loss in Meningioma Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Magnesium and Intraoperative Blood (...) Information provided by (Responsible Party): Mahidol University Study Details Study Description Go to Brief Summary: Meningioma is the most common central nervous system tumor and craniotomy with tumor removal was associated with moderate blood loss and blood transfusion. Magnesium has hypotensive effect and probably reduce intraoperative blood loss. Whether or not magnesium sulphate can reduce intraoperative blood loss and improve postoperative cognitive function is still inconlusive. So

2018 Clinical Trials

54. Magnesium for treating sickle cell disease. Full Text available with Trip Pro

Magnesium for treating sickle cell disease. Sickle cell disease is an autosomal recessive inherited haemoglobinopathy which causes painful vaso-occlusive crises due to sickle red blood cell dehydration. Vaso-occlusive crises are common painful events responsible for a variety of clinical complications; overall mortality is increased and life expectancy decreased compared to the general population. Experimental studies suggest that intravenous magnesium has proven to be well-tolerated (...) in individuals hospitalised for the immediate relief of acute (sudden onset) painful crisis and has the potential to decrease the length of hospital stay. Some in vitro studies and open studies of long-term oral magnesium showed promising effect on pain relief but failed to show its efficacy. The studies show that oral magnesium therapy may prevent sickle red blood cell dehydration and prevent recurrent painful episodes. There is a need to access evidence for the impact of oral and intravenous magnesium

2017 Cochrane

55. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. Full Text available with Trip Pro

stress.In this Phase IV, investigator-blinded trial (EudraCT: 2015-003749-24), healthy adults with Depression Anxiety Stress Scales (DASS-42) stress subscale score >18 and serum magnesium concentration 0.45 mmol/L-0.85 mmol/L, were randomized 1:1 to magnesium-vitamin B6 combination (Magne B6 [Mg-vitamin B6]; daily dose 300 mg and 30 mg, respectively) or magnesium alone (Magnespasmyl [Mg]; daily dose 300 mg). Outcomes included change in DASS-42 stress subscale score from baseline to Week 8 (primary (...) Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. Animal and clinical studies suggest complementary effects of magnesium and high-dose pyridoxine (vitamin B6) on stress reduction. This is the first randomized trial evaluating the effects of combined magnesium and vitamin B6 supplementation on stress in a stressed population with low magnesemia using a validated measure of perceived

2018 PLoS ONE Controlled trial quality: predicted high

56. Changes in the calcium and magnesium of the serum and in the inorganic phosphorus of the blood of cows at calving and of the calf during early life Full Text available with Trip Pro

Changes in the calcium and magnesium of the serum and in the inorganic phosphorus of the blood of cows at calving and of the calf during early life 16745445 2006 06 05 2018 11 13 0264-6021 28 3 1934 The Biochemical journal Biochem. J. Changes in the calcium and magnesium of the serum and in the inorganic phosphorus of the blood of cows at calving and of the calf during early life. 1004-7 Allcroft W M WM The Rowett Research Institute, Aberdeen. Godden W W eng Journal Article England Biochem J

1934 Biochemical Journal

57. The Effect on Serum Ionic Magnesium of Exchange Transfusion with Citrated as Opposed to Heparinized Blood Full Text available with Trip Pro

The Effect on Serum Ionic Magnesium of Exchange Transfusion with Citrated as Opposed to Heparinized Blood Serum Mg++ levels before, during, and after replacement transfusion were determined in 20 newborn infants. In 10 infants exchanged with acid-citrate-dextrose (ACD) blood, the level fell from 1.75 +/- 0.16 mEq./l. to 0.99 +/- 0.16 mEq./l. By contrast, levels in 10 infants exchanged with two types of heparinized blood were unchanged: the pre-exchange values were 1.59 +/- 0.11 (...) , and the postexchange levels were 1.59 +/- 0.08 mEq./l. Mean values for donor bloods were 0.42 +/- 0.07 mEq./l. with ACD blood, and 1.45 +/- 0.03 mEq./l. with heparinized blood. In vitro studies involving the addition of known amounts of citrate to standard Mg++ solutions demonstrated that the citrate caused a reduction of ionic magnesium. It is proposed that the fall in serum Mg++ when ACD blood is used for exchange transfusion is the combined result of Mg++ binding by the citrate, and the dilution effect

1967 Canadian Medical Association Journal

58. A SIMPLE AND RAPID METHOD FOR THE SIMULTANEOUS DETERMINATION OF CALCIUM AND MAGNESIUM FROM THE SAME SAMPLE OF BLOOD SERUM Full Text available with Trip Pro

A SIMPLE AND RAPID METHOD FOR THE SIMULTANEOUS DETERMINATION OF CALCIUM AND MAGNESIUM FROM THE SAME SAMPLE OF BLOOD SERUM A simple and rapid procedure has been developed for the complexometric titration of serum calcium and magnesium using "plasmocorinth B" as indicator. Both determinations can be carried out from the same 0.5 ml. sample. The method is in good agreement with the established calcium and magnesium methods.

1960 Journal of Clinical Pathology

59. Estimation of calcium and magnesium in blood serum by the cathode-ray polarograph Full Text available with Trip Pro

Estimation of calcium and magnesium in blood serum by the cathode-ray polarograph 13717909 1998 11 01 2018 11 30 0264-6021 79 1961 May The Biochemical journal Biochem. J. Estimation of calcium and magnesium in blood serum by the cathode-ray polarograph. 429-32 IRVING E A EA WATTS P S PS eng Journal Article England Biochem J 2984726R 0264-6021 I38ZP9992A Magnesium SY7Q814VUP Calcium OM Calcium blood Electrodes Humans Magnesium blood Polarography Serum CALCIUM/blood MAGNESIUM/blood 1961 5 1 1961

1961 Biochemical Journal

60. Serum magnesium and the risk of prediabetes: a population-based cohort study. Full Text available with Trip Pro

Serum magnesium and the risk of prediabetes: a population-based cohort study. Previous studies have found an association between serum magnesium and incident diabetes; however, this association may be due to reverse causation, whereby diabetes may induce urinary magnesium loss. In contrast, in prediabetes (defined as impaired fasting glucose), serum glucose levels are below the threshold for urinary magnesium wasting and, hence, unlikely to influence serum magnesium levels. Thus, to study (...) the directionality of the association between serum magnesium levels and diabetes, we investigated its association with prediabetes. We also investigated whether magnesium-regulating genes influence diabetes risk through serum magnesium levels. Additionally, we quantified the effect of insulin resistance in the association between serum magnesium levels and diabetes risk.Within the population-based Rotterdam Study, we used Cox models, adjusted for age, sex, lifestyle factors, comorbidities, kidney function

2017 Diabetologia

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