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Serum Ferritin

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81. Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months. (Abstract)

Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months. An ongoing challenge has been determining clinically relevant serum ferritin cut-offs in the diagnosis of iron deficiency in children aged 1-3 years. We identified 2 potential clinically relevant serum ferritin cut-off values through their association with clinically important cut-off of hemoglobin as the indicator of anemia.Copyright © 2017 Elsevier Inc. All rights reserved.

2017 Journal of Pediatrics

82. [Effect of lifting-thrusting reinforcing-reducing manipulations of acupuncture on serum ferritin content and total iron binding capacity in blood-deficiency syndrome rabbits]. (Abstract)

[Effect of lifting-thrusting reinforcing-reducing manipulations of acupuncture on serum ferritin content and total iron binding capacity in blood-deficiency syndrome rabbits]. To observe the influence of lift-thrust reinforcing-reducing manipulations of acupuncture on serum ferritin (SF) content and total iron binding capacity (TIBC) in blood-deficiency syndrome rabbits so as to study its underlying mechanisms.Sixty Japanese white rabbits were randomized into blank control,model, acupuncture (...) in comparison with pre-treatment after modeling (P < 0.05). No significant differences were found between the reinforcing and reducing groups in both serum SF and TIBC levels (P > 0.05).Both reinforcing and reducing manipulation of acupuncture of "Zusanli" (ST 36) can up-regulate serum SF content and down-regulate TIBC level in blood-deficiency syndrome rabbits, which may contribute to their effects in improving blood-deficiency syndrome and has no significant difference.

2012 Zhen ci yan jiu = Acupuncture research / [Zhongguo yi xue ke xue yuan Yi xue qing bao yan jiu suo bian ji]

83. A genetic risk factor for low serum ferritin levels in Danish blood donors. (Abstract)

A genetic risk factor for low serum ferritin levels in Danish blood donors. Iron deficiency is a frequent side effect of blood donation. In recent years, several studies have described genetic variants associated with iron concentrations. However, the impact of these variants on iron levels is unknown in blood donors. Knowledge of genetic variants that predispose donors to iron deficiency would allow bleeding frequency and iron supplementation to be tailored to the individual donor.The (...) genotypes of five specific single-nucleotide polymorphisms (SNPs) in three genes that have been previously associated with iron status and/or restless leg syndrome (RLS) were investigated in two groups of female blood donors. The first group had low iron stores (serum ferritin ≤ 12 µg/L, n = 657), and the second group had normal to high iron stores (serum ferritin > 30 µg/L, n = 645). Genotype distribution for each of the SNPs was compared between the two groups.Homozygosity for the T-allele of BTBD9

2012 Transfusion

84. Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels. Full Text available with Trip Pro

Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels. Body iron status has been linked to atherosclerosis in adults. The purposes of our study were to determine (1) the association between circulating ferritin levels and carotid intima-media thickness (cIMT) in a cohort of apparently healthy children and (2) the association between cIMT and parental ferritin levels.Circulating ferritin levels (microparticle enzyme immunoassay (...) ), metabolic parameters, and cIMT (ultrasonography) were analyzed cross-sectionally in a cohort of 692 healthy white children with a mean age of 8 ± 2 years (52% girls and 48% boys). In consecutive 123 children from the cross-sectional sample, the same serum assessments were also performed at baseline in their parents, and the cIMT was repeated after 3 years of follow-up in the children at a mean age of 11 ± 2 years (53% girls and 47% boys). Weak but significant positive associations were evident between

2015 Thrombosis and Vascular Biology

85. Relation of maternal and cord blood serum ferritin. Full Text available with Trip Pro

Relation of maternal and cord blood serum ferritin. Serum ferritin was measured in 51 term normal pregnant mothers and the corresponding cord blood samples. All of the mothers had received prophylactic oral iron and folate during pregnancy. The mean (+/-SD) maternal serum ferritin at the end of pregnancy was 58 +/- 42.9 microgram/l (range 16-201 microgram/l), compared to a mean of 183.2 +/- 61.2 microgram/l (range 62-313 microgram/l) in these newborns. No correlation was found between (...) the serum ferritin of mothers and babies, nor between the serum ferritin and serum iron of mothers at the end of pregnancy or between these parameters in the newborn.

1977 Archives of Disease in Childhood

86. Questions about horse spleen ferritin crossing the blood brain barrier via mouse transferrin receptor 1 Full Text available with Trip Pro

Questions about horse spleen ferritin crossing the blood brain barrier via mouse transferrin receptor 1 28993977 2018 07 20 2018 11 13 1674-8018 8 11 2017 11 Protein & cell Protein Cell Questions about horse spleen ferritin crossing the blood brain barrier via mouse transferrin receptor 1. 788-790 10.1007/s13238-017-0481-8 Fan Kelong K Key Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics (...) of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. yanxy@ibp.ac.cn. University of Chinese Academy of Sciences, Beijing, 100049, China. yanxy@ibp.ac.cn. eng Journal Article Germany Protein Cell 101532368 1674-800X 0 Receptors, Transferrin 0 Tfrc protein, mouse 9007-73-2 Ferritins IM Animals Blood-Brain Barrier metabolism Ferritins metabolism Horses Mice Receptors, Transferrin metabolism Spleen chemistry 2017 10 11 6 0 2018 7 22 6 0 2017 10 11 6 0 ppublish 28993977 10.1007/s13238-017-0481-8

2017 Protein & cell

87. Serum Ferritin

Serum Ferritin Serum Ferritin Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Serum Ferritin Serum Ferritin Aka: Serum Ferritin (...) , Ferritin From Related Chapters II. Indications Evaluation for Screening for III. Physiology Indicator of total body iron stores Most reliable indicator other than Acute phase reactant IV. Interpretation: Normal Range: 18-300 ng/ml V. Interpretation: Increased Inflammatory states disease (necrotic hepatocytes) and s (very high, Ferritin >5000) VI. Interpretation: Decreased Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Serum

2018 FP Notebook

88. The use of iron salts, elevated levels of hemoglobin and serum ferritin during gestation and the risk of developing gestational diabetes: a systematic review

The use of iron salts, elevated levels of hemoglobin and serum ferritin during gestation and the risk of developing gestational diabetes: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr (...) to be extracted: animal model Example: Dose, timing of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary

2018 PROSPERO

89. Ferritin in glioblastoma. (Abstract)

Ferritin in glioblastoma. Elevated levels of serum ferritin (SF) are observed in several types of cancer; however, little is known on the association between ferritin and glioma, the most frequent type of human primary brain tumour. Here we report that GBM patients show significantly increased pre-surgical SF levels (i.e. ferritinaemia) within the SF reference range and a marked ferritin immunoreactivity of resected tumour tissue. Our findings account for an indirect association between (...) ferritin synthesis in glioma-tissue and altered SF levels, which limits the clinical value of SF as a tumour marker in glioma. Importantly, we show for the first time that GBM-derived glioma cells release ferritin in vitro, which exerts an apoptosis-stimulating activity. Albeit the pathophysiologic context of apoptosis induction by a tumour-derived ferritin remains to be defined, our findings account for a distinct growth-regulatory role of these ferritin species in tumour biology.

2020 British Journal of Cancer

90. Association between Serum Ferritin Concentrations and Depressive Symptoms among Chinese Adults: A Population Study from the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIHealth) Cohort Study. Full Text available with Trip Pro

Association between Serum Ferritin Concentrations and Depressive Symptoms among Chinese Adults: A Population Study from the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIHealth) Cohort Study.

2016 PLoS ONE

91. Relationship of Iron Deficiency and Serum Ferritin Levels with Pulmonary Hypertension: The Jackson Heart Study. Full Text available with Trip Pro

Relationship of Iron Deficiency and Serum Ferritin Levels with Pulmonary Hypertension: The Jackson Heart Study. Iron deficiency is prevalent in idiopathic pulmonary arterial hypertension (IPAH), but whether iron deficiency or ferritin levels are associated with pulmonary hypertension (PH) in the general population is unknown.We performed a cross-sectional analysis of data on iron deficiency (exposure), and PH (pulmonary artery systolic pressure>40mmHg on echocardiogram) (outcome) on subjects (...) with complete data on exposures and outcomes as well as covariates (n = 2,800) enrolled in the Jackson Heart Study, a longitudinal prospective observational cohort study of heart disease in African-Americans from Jackson, Mississippi. Iron deficiency was defined as a serum ferritin level < 15ng/mL (females); < 30ng/mL (males). We determined crude prevalence ratios (PRs) for PH in iron deficient versus non-iron deficient groups using modified Poisson regression modeling. We also analyzed the prevalence of PH

2016 PLoS ONE

92. Presence of Serum Ferritin before and after Bariatric Surgery: Analysis in Dentate and Edentulous Patients. Full Text available with Trip Pro

Presence of Serum Ferritin before and after Bariatric Surgery: Analysis in Dentate and Edentulous Patients. Society has changed its own lifestyle, specially its eating habits and physical activities, leading to excessive weight and a sedentary behavior, which has contributed to obesity increase. Bariatric surgery is the most effective treatment to obesity, allowing weight loss and its maintenance. However, it has been related high levels of iron deficiency after surgery. A person's nutritional (...) status might be affected by total or partial tooth loss. The aim of this longitudinal prospective cohort study was to evaluate the levels of serum ferritin before and after bariatric surgery and to identify if there is a relation with tooth loss. The sample was composed of 50 patients selected and assisted at Amaral Carvalho Hospital, located in Jaú city, Brazil. The use and necessity of prosthesis, dental absence or presence, and serum ferritin dosage were evaluated. Student's t test, Univariate

2016 PLoS ONE

93. Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes. Full Text available with Trip Pro

Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes. Although the carcinogenic potential of iron has been shown, evidence from observational studies that have linked serum iron variables and cancer outcomes has been inconsistent.We investigated whether higher iron concentrations increased risk of cancer outcomes.A prospective examination of iron biomarkers as independent risk factors for cancer was assessed in 1597 men (...) and 1795 women aged 25-79 y who participated in the 1994/1995 Busselton Health Survey and had relevant data, no history of cancer before the survey, and serum ferritin concentrations ≥20 μg/L. Follow-up for incident cancers and death from cancer was available to 2010. Proportional hazards regression modeling was performed to investigate if iron status predicted cancer incidence and mortality.After adjustments for age, smoking, drinking, anthropometric and biochemical variables, or menopausal status

2016 American Journal of Clinical Nutrition

94. Comparative analysis of serum iron, serum ferritin and red cell folate levels among breast fed, fortified milk and cow’s milk fed infants Full Text available with Trip Pro

Comparative analysis of serum iron, serum ferritin and red cell folate levels among breast fed, fortified milk and cow’s milk fed infants Iron and folic acid are essential nutrients needed for hematopoiesis. Infants' diet is commonly deficient in these micronutrients that lead to nutritional anemia. Aim of this study was to determine serum iron, serum ferritin and red cell folate levels among healthy breast fed, fortified milk and cow's milk fed infants.A total of 120 infants of 4-9 months (...) of age were enrolled in this study. It included 40 normal breast fed controls, 40 fortified milk fed (FM) and 40 cow's milk fed (CM) infants. Serum iron, serum ferritin and red cell folate concentrations were determined using colorimetric and enzyme immunoassay techniques.Mean serum iron, serum ferritin and red cell folate concentrations of breast fed control group were 120.9±68.4µg/dl, 109±71.7ng/ml and 1044.1±409.2ng/ml respectively. Fortified milk (FM) group showed significantly decreased serum

2015 Pakistan Journal Of Medical Sciences

95. Estimating Iron Overload in Patients with Suspected Liver Disease and Elevated Serum Ferritin (Abstract)

Estimating Iron Overload in Patients with Suspected Liver Disease and Elevated Serum Ferritin Iron status evaluation in patients with suspected liver disease and elevated serum ferritin is often challenging because hyperferritinemia does not always indicate iron overload. A reliable approach to estimate iron overload without exposing the patient to unnecessary investigations would help the clinician to identify patients who may take advantage of iron-removal therapy.We analyzed all liver (...) biopsies, including measurement of hepatic iron concentration, performed at the University Hospital Zurich from 1997 to 2010 to identify clinical and laboratory predictors of iron overload in patients with elevated serum ferritin (n = 147).Hyperferritinemia was predictive of iron overload only in patients with a high level of serum ferritin (>2000 μg/L). In patients with moderate hyperferritinemia, liver transaminases inversely correlated with hepatic iron concentration. A combination of both

2014 EvidenceUpdates

96. Elevated Serum Ferritin Full Text available with Trip Pro

Elevated Serum Ferritin 25138336 2014 08 25 2018 11 13 1538-3598 312 7 2014 Aug 20 JAMA JAMA Elevated serum ferritin. 743-4 10.1001/jama.2014.302 VanWagner Lisa B LB Departments of Preventive Medicine and Medicine, Division of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Green Richard M RM Department of Medicine, Division of Gastroenterology & Hepatology, Section of Hepatology, Northwestern University Feinberg School of Medicine, Chicago (...) , Illinois. eng F32 HL116151 HL NHLBI NIH HHS United States 1F32HL116151-01 HL NHLBI NIH HHS United States Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States JAMA 7501160 0098-7484 9007-73-2 Ferritins AIM IM JAMA. 2014 Dec 17;312(23):2572 25514310 JAMA. 2014 Dec 17;312(23):2572 25514312 Alcohol Drinking Arthritis, Reactive Biopsy Ferritins blood Hemochromatosis complications diagnosis genetics therapy Humans Liver pathology Male Middle Aged

2014 JAMA

97. A High Serum Iron Level Causes Mouse Retinal Iron Accumulation Despite an Intact Blood-Retinal Barrier Full Text available with Trip Pro

A High Serum Iron Level Causes Mouse Retinal Iron Accumulation Despite an Intact Blood-Retinal Barrier The retina can be shielded by the blood-retinal barrier. Because photoreceptors are damaged by excess iron, it is important to understand whether the blood-retinal barrier protects against high serum iron levels. Bone morphogenic protein 6 (Bmp6) knockout mice have serum iron overload. Herein, we tested whether the previously documented retinal iron accumulation in Bmp6 knockout mice might (...) were the same as, or greater than, those in age-matched wild-type retinas, indicating that Bmp6 knockout does not cause retinal hepcidin deficiency. Changes in mRNA levels of L ferritin and transferrin receptor indicated increased retinal iron levels in i.v. iron-injected wild-type mice. Oxidative stress markers were elevated in photoreceptors of mice receiving i.v. iron. These findings suggest that elevated serum iron levels can overwhelm local retinal iron regulatory mechanisms.

2014 The American journal of pathology

98. High serum adiponectin is associated with low blood haemoglobin in elderly men: the Swedish MrOS study. (Abstract)

High serum adiponectin is associated with low blood haemoglobin in elderly men: the Swedish MrOS study. Blood haemoglobin (Hb) concentration declines in elderly men, whilst the level of the adipocyte-derived protein adiponectin increases with age. The association between erythropoiesis and adiponectin in elderly men is unclear. The aim of this study was to determine whether adipokines such as adiponectin and leptin are associated with anaemia and Hb concentration in elderly community-dwelling (...) with adiponectin level (r = 0.13, P < 0.001). In age-adjusted partial correlations, Hb and adiponectin levels were negatively correlated (r = -0.20, P < 0.001); this association remained significant after multivariable adjustment for age, body composition, EPO, fasting insulin, sex hormones, leptin and ferritin. Age-adjusted mean adiponectin concentrations were significantly higher in anaemic men (66/1005; Hb <130 g L(-1) ) compared to nonanaemic men (14.0 vs. 11.7 μg mL(-1) , P < 0.05). In multivariate

2014 Journal of internal medicine

99. Ferritin Genes Overexpression in PBMC and a Rise in Exercise Performance as an Adaptive Response to Ischaemic Preconditioning in Young Men. Full Text available with Trip Pro

Ferritin Genes Overexpression in PBMC and a Rise in Exercise Performance as an Adaptive Response to Ischaemic Preconditioning in Young Men. The proposal of this study was to evaluate the effect of acute and ten-day ischaemic preconditioning (IPC) training procedure on the Wingate Anaerobic Test (WAnT), the ferritin H (FTH), ferritin L (FTL), and transferrin receptor 1 (TFRC) mRNA expression in peripheral blood mononuclear cells (PBMC), and anaerobic performance.34 healthy men volunteers (aged (...) 20.7 ± 1.22 years) participated in the study. The effects of bilateral upper limb IPC and sham controlled condition were assessed in two experimental protocols: (a) the influence of acute (one time) IPC based on an experimental crossover study design and (b) the influence of ten-day IPC training treatment based on a random group assignment. At the beginning and at the end of each experiment upper body WAnT was performed and blood samples were collected to assess gene expression via quantitative PCR

2019 BioMed research international Controlled trial quality: uncertain

100. Within-individual differences in plasma ferritin, retinol-binding protein, and zinc concentrations in relation to inflammation observed during a short-term longitudinal study are similar to between-individual differences observed cross-sectionally. Full Text available with Trip Pro

Within-individual differences in plasma ferritin, retinol-binding protein, and zinc concentrations in relation to inflammation observed during a short-term longitudinal study are similar to between-individual differences observed cross-sectionally. Cross-sectional (CS) surveys indicate that individuals with acute inflammation have higher plasma ferritin (pF), and lower retinol-binding protein (RBP) and zinc (pZn) concentrations than those without. In populations with a high burden of infection (...) (pF, soluble transferrin receptor [sTfR], RBP, and pZn), and compare them to CS differences.Two blood samples were obtained 21 d apart from 451 asymptomatic Burkinabé children aged 6-23 mo. To calculate CFs, inflammation was defined as CRP >5 mg/L or AGP >1 g/L, or both. The RC approach adjusted MN biomarkers to a presumably healthy reference point within the study population (10th percentile CRP or AGP concentration). CS CFs and RCs were estimated from a naive regression model, treating

2019 American Journal of Clinical Nutrition

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