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Serum Ferritin

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5841. Serum ferritin in normal individuals and in patients with malignant lymphoma and chronic renal failure measured with seven different commercial immunoassay techniques. Full Text available with Trip Pro

Serum ferritin in normal individuals and in patients with malignant lymphoma and chronic renal failure measured with seven different commercial immunoassay techniques. A comparison of serum ferritin determination by seven different commercial immunoassay techniques gave mean coefficients of variation of 57% for normal individuals, 41 . 4% for patients with malignant lymphoma and 43 . 1% for patients with chronic renal failure. One of the immunoradiometric assays gave consistently higher serum (...) ferritin values in both normal and patient groups; mean values were increased (greater than 100% for normal males, greater than 50% for normal females) with respect to the other assays. Underestimation of serum ferritin by an enzyme-linked immunosorbent assay was also evident. Results were affected by storage conditions, but not by dilution of samples, in two kits. Solutions of ferritin purified from normal and malignant human and mouse tissues, and lymphoma isoferritins, were used for reference

1982 Journal of Clinical Pathology

5842. Detection of a glycosylated subunit in human serum ferritin. Full Text available with Trip Pro

Detection of a glycosylated subunit in human serum ferritin. Ferritin was purified from the serum of two patients with idiopathic haemochromatosis. The protein contained three types of subunit--the H and L subunits of tissue ferritins (although only a trace of H could be detected) and a third subunit, 'G', with the highest apparent molecular weight. Only the 'G' subunit band stained for carbohydrate, indicating that a proportion of the subunits of human serum ferritin are glycosylated. Although (...) serum was obtained from patients with idiopathic haemochromatosis, it is probable that the 'G' subunit is a component of normal serum ferritin.

1981 Biochemical Journal

5843. High Prevalence of Helicobacter pylori in the Alaska Native Population and Association with Low Serum Ferritin Levels in Young Adults Full Text available with Trip Pro

High Prevalence of Helicobacter pylori in the Alaska Native Population and Association with Low Serum Ferritin Levels in Young Adults Iron deficiency anemia is a common public health problem in the Alaska Native population. Yet, a clear etiology has eluded researchers for decades. Previous studies suggested a link between Helicobacter pylori infection, gastrointestinal blood loss due to hemorrhagic gastritis, and generalized iron deficiency anemia in adult Alaska Natives. Therefore, we examined (...) the association between the prevalence of H. pylori-specific immunoglobulin G (IgG) and serum ferritin levels, a marker of iron deficiency. A random sample of 2,080 serum samples from Alaska Native residents drawn between 1980 and 1986 from residents in 13 regions was selected, and the samples were stratified by age, sex, and region. Overall, 75% were positive for H. pylori-specific IgG. The rate of H. pylori seropositivity increased with age; by age 14 years, 78% of the residents were positive. There were

2000 Clinical and Diagnostic Laboratory Immunology

5844. Serum ferritin level in neonatal fulminant liver failure Full Text available with Trip Pro

Serum ferritin level in neonatal fulminant liver failure 11710325 2001 12 07 2015 11 19 1359-2998 85 3 2001 Nov Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Serum ferritin level in neonatal fulminant liver failure. F226 Lee W S WS McKiernan P J PJ Kelly D A DA eng Letter England Arch Dis Child Fetal Neonatal Ed 9501297 1359-2998 0 Biomarkers 9007-73-2 Ferritins AIM IM Biomarkers blood Ferritins blood Hemochromatosis blood complications Humans (...) Infant, Newborn Liver Failure blood etiology Retrospective Studies Sensitivity and Specificity 2001 11 17 10 0 2002 1 5 10 1 2001 11 17 10 0 ppublish 11710325 PMC1721327

2001 Archives of Disease in Childhood. Fetal and Neonatal Edition

5845. Bilateral cataract and high serum ferritin: a new dominant genetic disorder? Full Text available with Trip Pro

Bilateral cataract and high serum ferritin: a new dominant genetic disorder? 8558554 1996 02 28 2018 11 13 0022-2593 32 10 1995 Oct Journal of medical genetics J. Med. Genet. Bilateral cataract and high serum ferritin: a new dominant genetic disorder? 778-9 Bonneau D D Service de Pédiatrie et Génétique, CHU de Poitiers, France. Winter-Fuseau I I Loiseau M N MN Amati P P Berthier M M Oriot D D Beaumont C C eng Case Reports Journal Article England J Med Genet 2985087R 0022-2593 9007-73-2 (...) Ferritins IM Cataract blood genetics Child Female Ferritins blood genetics Genes, Dominant Humans Male Metabolism, Inborn Errors genetics Pedigree 1995 10 1 1995 10 1 0 1 1995 10 1 0 0 ppublish 8558554 PMC1051699 N Engl J Med. 1975 May 1;292(18):951-6 1090831 Somat Cell Mol Genet. 1994 Jan;20(1):67-9 8197479 Hum Genet. 1985;69(4):371-4 3857215 Clin Haematol. 1982 Jun;11(2):275-307 6176386

1995 Journal of Medical Genetics

5846. Reliability of serum iron, ferritin, nitrite, and association with risk of renal cancer in women Full Text available with Trip Pro

Reliability of serum iron, ferritin, nitrite, and association with risk of renal cancer in women Reliability of serum levels of iron, ferritin and nitrite (NO(2)(-)) over a 2-year period were evaluated in 40 healthy women (20 pre-menopausal and 20 post-menopausal), ages 39-65 years, from the New York University Women's Health Study (NYUWHS). Three blood samples per woman collected at yearly intervals were analyzed. Reliability coefficients (RCs) of serum iron, ferritin, and nitrite were 0.03 (...) (95% confidence interval (CI), 0-0.33), 0.90 (95% CI, 0.79-0.95), and 0.72 (95% CI, 0.50-0.86), respectively, for pre-menopausal women, and 0.26 (95% CI, 0-0.56), 0.77 (95% CI, 0.59-0.89), and 0.55 (95% CI, 0.30-0.77), respectively, for post-menopausal women. In a case-control study nested within NYUWHS cohort, serum levels of nitrite, ferritin, and iron were measured in women apparently healthy at the time of blood donation but diagnosed with renal cancer 1.8-12.2 years later (n=24

2003 Cancer Detection and Prevention

5847. The effect of iron treatment on serum ferritin concentrations and bone marrow stainable iron in iron deficient out-patients with gastritis, gastric ulcer and duodenal ulcer. (Abstract)

The effect of iron treatment on serum ferritin concentrations and bone marrow stainable iron in iron deficient out-patients with gastritis, gastric ulcer and duodenal ulcer. Serum ferritin concentrations and bone marrow stainable iron were determined in 122 adult out-patients (seventy males) with gastritis, gastric ulcer and duodenal ulcer. Half of the forty-four patients with iron deficiency (serum ferritin level below 20 micrograms/l) received peroral iron therapy (200 mg Fe++ daily). In most (...) of the treated patients serum ferritin levels increased and the amount of bone marrow stainable iron in half of them also increased. Measurement of body iron stores by serum ferritin determinations and restoration of low body iron stores in these patients is of practical importance.

1984 The Journal of international medical research Controlled trial quality: uncertain

5848. Effect of laparoscopic sterilization and insertion of Multiload Cu 250 and Progestasert IUDs on serum ferritin levels. (Abstract)

Effect of laparoscopic sterilization and insertion of Multiload Cu 250 and Progestasert IUDs on serum ferritin levels. Blood haemoglobin and serum ferritin levels were measured at the initial visit and 12 months following sterilization and IUD insertion. Ferritin levels were unaltered in Progestasert users after 12 months but haemoglobin values increased though not significantly. Ferritin levels fell in Multiload Cu 250 users and in sterilized women; haemoglobin levels were also observed (...) acceptability. Menstrual blood loss studies may help explain why anaemia develops after sterilization.

1983 Contraception Controlled trial quality: uncertain

5849. The ratio of serum transferrin receptor and serum ferritin in the diagnosis of iron status. (Abstract)

The ratio of serum transferrin receptor and serum ferritin in the diagnosis of iron status. Laboratory tests used in the diagnosis of iron status lack specificity in defining iron deficiency anaemia (IDA) and anaemia of inflammation (AI). The serum transferrin receptor (sTfR) may provide more information in this regard. The iron status of 561 pre-school children was determined and classified using the conventional measurements. The value of the concentration of sTfR, the ratio of sTfR (microg

2001 British journal of haematology

5850. Serum Ferritin is a Reliable, Non-invasive Test for Iron Status in Pregnancy: Comparison of Ferritin with Other Iron Status Markers in a Longitudinal Study on Healthy Pregnant Women; Erythropoiesis. (Abstract)

Serum Ferritin is a Reliable, Non-invasive Test for Iron Status in Pregnancy: Comparison of Ferritin with Other Iron Status Markers in a Longitudinal Study on Healthy Pregnant Women; Erythropoiesis. Background and Aims: To assess the true positive and false positive rates of the iron status markers (serum iron, serum transferrin, transferrin saturation, haemoglobin, haematocrit, mean corpuscular volume (MCV), mean cell haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC (...) ), erythrocyte count) in the diagnosis of depleted iron stores (iron depletion) during normal pregnancy and postpartum. Methods: Among 120 pregnant women, 58 were randomised to placebo-treatment and 62 to iron-treatment (66 mg ferrous iron daily from 14 weeks of gestation). Iron status markers were measured every 4th week during pregnancy and 8 weeks postpartum. Iron depletion was defined by a serum ferritin concentration < 16 &mgr;g/L. The 5th percentiles for the other iron status markers in the group

2000 Hematology (Amsterdam, Netherlands) Controlled trial quality: uncertain

5851. Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins: a randomized cross-over trial in male smokers. (Abstract)

Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins: a randomized cross-over trial in male smokers. The purpose of this study was to test the hypothesis that the reduction of body iron stores by venesection (blood letting) would reduce the susceptibility to oxidation of atherogenic serum lipoproteins.This is a randomized, controlled cross-over trial in 14 regularly smoking men with elevated serum ferritin concentration. The study design comprised two 14 (...) ) of blood three times in 14 weeks.Oxidation resistance of very low density lipoprotein (VLDL)/low density lipoprotein (LDL) was measured after inducing oxidation with haemin and H2O2.Serum ferritin concentration was reduced by 44% [95% confidence interval (CI) 8-82%, P = 0.021] during the venesection periods, the maximal oxidation velocity was decreased by 20% (95% CI 3-30%, P = 0.032), and the lag time to start of oxidation was lengthened (oxidation resistance increased) by 33% (95% CI 1-64%, P = 0.036

1995 Journal of internal medicine Controlled trial quality: uncertain

5852. Cord serum erythropoietin in 90 healthy newborn term infants: relationship to blood gases and iron status markers. (Abstract)

Cord serum erythropoietin in 90 healthy newborn term infants: relationship to blood gases and iron status markers. In this study, we examined the cord serum erythropoietin (EPO) level in newborn infants in relation to venous cord blood gases and iron status markers (cord serum ferritin, cord serum transferrin saturation). The subjects were 90 healthy newborn term infants with a normal birth and 90 healthy women with an uncomplicated pregnancy and delivery. Within 14-18 weeks of gestation, 47 (...) prospective mothers, allocated at random, received tablets containing 66 mg ferrous iron daily, and 43 received a placebo. Serum EPO was measured in women prior to delivery. Serum EPO, serum ferritin and serum transferrin saturation were analyzed in cord blood from the newborn. Blood gases (PO2, PCO2 and standard HCO3, PH) were measured in venous cord blood and Apgar scores were recorded. The cord serum EPO level in the newborn was not significantly affected by the iron supplementation to the mothers

1996 International journal of hematology Controlled trial quality: uncertain

5853. Failure of twice-weekly iron supplementation to increase blood haemoglobin and serum ferritin concentrations: results of a randomized controlled trial. (Abstract)

Failure of twice-weekly iron supplementation to increase blood haemoglobin and serum ferritin concentrations: results of a randomized controlled trial. In order to increase the intestinal absorption of iron whilst simultaneously minimising the side-effects and thus increasing compliance, once- or twice-weekly, instead of daily, iron supplementation has been widely recommended. In a randomized, placebo-controlled, double-blind study in western Kenya, a tablet of ferrous dextran (containing 60 mg (...) elemental iron) or an identical-looking placebo tablet was provided twice-weekly for 12 months to each child or adult investigated. At baseline each subject had a moderately low blood concentration of haemoglobin (Hb). Initial Hb and serum ferritin (SF) concentrations were determined and each subject was tested for malarial and helminth infection and treated, if necessary, with the appropriate anthelminthic drug(s). Overall, 200 children (aged 4-15 years) and 129 adults (aged 16-63 years) completed

2006 Annals of Tropical Medicine and Parasitology Controlled trial quality: predicted high

5854. A study of serum ferritin levels among male blood donors in Hospital Universiti sains Malaysia. (Abstract)

A study of serum ferritin levels among male blood donors in Hospital Universiti sains Malaysia. Iron deficiency is the commonest cause of anemia worldwide and healthy blood donors are estimated to lose about 236 mg of iron with each donation. The objective of this study was to determine the serum ferritin levels among first time and regular male blood donors, and also to correlate the serum ferritin levels with the number of donations and hemoglobin levels. Hemoglobin levels and serum ferritin (...) were measured in three groups of donors divided into first time donors; (n = 92), donors with 2-4 donations (n = 41), and regular donors (n = 78). The mean hemoglobins in the first time donors, second group and regular blood donor group were 14.95 +/- 1.08, 15.12 +/- 1.44 and 15.56 +/- 1.48, respectively. The serum ferritin level were found to be significantly lower among the regular donors (62.0 +/- 39.78 ng/ml) compared to first time donors (90.7 +/- 66.63) and second group donors (114.12

2006 Southeast Asian Journal of Tropical Medicine and Public Health

5855. Serum total cholesterol and ferritin and blood haemoglobin concentrations in primary schoolchildren. Full Text available with Trip Pro

Serum total cholesterol and ferritin and blood haemoglobin concentrations in primary schoolchildren. Serum total cholesterol and ferritin and haemoglobin concentrations were measured in blood samples obtained by venepuncture in 378 of 593 children aged 5-6 or 8-9 years from seven primary schools in Canterbury. This study formed part of an investigation to assess the feasibility of including a venepuncture procedure for monitoring purposes in primary schoolchildren. Although only one child had (...) a very low haemoglobin concentration of 61 g/l, a large percentage, 25% in the rising 6 years and 7% in the rising 9 years, had concentrations between 100 and 115 g/l--that is, less than the reference fifth centile. Eight per cent had a serum ferritin concentration less than 8 micrograms/l. Cholesterol concentrations higher than 5.2 mmol/l were found in 20% of the 5-6 year olds and 23% of the 8-9 year olds, and in 19% of boys and 25% of girls. About 5% of children had cholesterol concentrations above

1994 Archives of Disease in Childhood

5856. Response in serum ferritin and haemoglobin to iron therapy in blood donors. (Abstract)

Response in serum ferritin and haemoglobin to iron therapy in blood donors. Seven hundred seventeen healthy male blood donors regularly donating four or more units a year were surveyed for haemoglobin and serum ferritin levels. One hundred fifty-one (21%) had a haemoglobin less than 13.5 g/dl and were therefore disqualified from further blood donation, having a mean serum ferritin of 28 micrograms/liter. Of the remaining 566 donors with haemoglobin levels equal to or greater than 13.5 g/dl (...) , the mean serum ferritin was 33 micrograms/liter, although in 299 (53%) the value was less than 28 micrograms/liter. To document response to iron therapy 46 donors with haemoglobin levels equal to or greater than 13.5 g/dl were stratified into those with the lowest iron stores (group 1; n = 23), defined as a serum ferritin less than 20 micrograms/liter, and controls (group 2; n = 23), with serum ferritin between 50 and 150 micrograms/liter. Within each stratum donors randomly received ferric polymaltose

1988 American journal of hematology Controlled trial quality: uncertain

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