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Serum Ferritin

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5701. Serum ferritin, liver iron stores, and liver histology in children with thalassaemia. Full Text available with Trip Pro

Serum ferritin, liver iron stores, and liver histology in children with thalassaemia. Serum ferritin, liver iron stores, and liver histology were studied in 38 children with thalassaemia major who were being treated by regular blood transfusions. There was no correlation between serum ferritin levels and either the number of transfusions or the amount of iron deposited in the liver. However, for a given level of iron stores, ferritin levels were higher in patients with chronic hepatitis (...) (including chronic aggressive and chronic persistent forms) than in those with hepatic siderosis only. We conclude that serum ferritin reflects tissue iron deposits in regularly transfused thalassaemic patients, only in the absence of hepatitis.

1980 Archives of Disease in Childhood

5702. Lack of correlation between free erythrocyte porphyrin and serum ferritin values at birth and at 2 months of life in low birthweight infants. Full Text available with Trip Pro

Lack of correlation between free erythrocyte porphyrin and serum ferritin values at birth and at 2 months of life in low birthweight infants. Red cell free erythrocyte porphyrin and serum ferritin determinations were performed on capillary blood specimens from 63 healthy infants weighing 2500 g or less at birth, during the first week of life, and, from 44 of them, again at 8-10 weeks. Free erythrocyte porphyrin values were high both at 3-7 days (mean 156 microgram/100 ml RBC) and at 8-10 weeks (...) (mean 128 microgram/100 ml RBC). The respective serum ferritin values were also high (mean 226 and 107 ng/ml), excluding a depletion in iron stores. In addition, no correlation was found between free erythrocyte porphyrin and serum ferritin values either at birth or at age 2 months. These findings are consistent with an earlier hypothesis that in the presence of iron stores, the rate of iron release from the stores in low birthweight infants may not be sufficient to maintain optimal erythropoiesis

1983 Archives of Disease in Childhood

5703. EDTA plasma rather than serum for B12, folate and ferritin estimations? Full Text available with Trip Pro

EDTA plasma rather than serum for B12, folate and ferritin estimations? 4056074 1985 12 03 2018 11 13 0021-9746 38 10 1985 Oct Journal of clinical pathology J. Clin. Pathol. EDTA plasma rather than serum for B12, folate and ferritin estimations? 1197 Sviland L L Rodger R S RS Fail J B JB Hamilton P J PJ eng Letter England J Clin Pathol 0376601 0021-9746 9007-73-2 Ferritins 935E97BOY8 Folic Acid P6YC3EG204 Vitamin B 12 AIM IM Ferritins blood Folic Acid blood Humans Plasma Vitamin B 12 blood 1985

1985 Journal of Clinical Pathology

5704. IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin. Full Text available with Trip Pro

IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin. In order to study an experimental model of IgA nephropathy, C3H/HeJ mice which are high IgA responders were strongly immunized orally with ferritin and compared to syngeneic C3H/eB. C3H/HeJ exhibited a significant increase of total IgA level in the serum and of IgA deposits in the mesangium. However the low level of IgA antibody to ferritin detected in the serum and the unsuccessful search (...) for ferritin and antibody to ferritin in the glomeruli suggest that strong oral immunization of C3H/HeJ mice leads to high level of non specific IgA in the serum and deposition of IgA in the kidney.

1986 Clinical and experimental immunology

5705. Serum ferritin: an indicator of iron responsive anaemia in patients with RA? Full Text available with Trip Pro

Serum ferritin: an indicator of iron responsive anaemia in patients with RA? 3592795 1987 07 16 2018 11 13 0003-4967 46 4 1987 Apr Annals of the rheumatic diseases Ann. Rheum. Dis. Serum ferritin: an indicator of iron responsive anaemia in patients with RA? 349-50 Cavill I I Radford M M eng Letter England Ann Rheum Dis 0372355 0003-4967 9007-73-2 Ferritins IM Anemia blood Arthritis, Rheumatoid blood Ferritins blood Humans 1987 4 1 1987 4 1 0 1 1987 4 1 0 0 ppublish 3592795 PMC1002135 Clin

1987 Annals of the Rheumatic Diseases

5706. Serum ferritin concentration in sickle cell crisis. Full Text available with Trip Pro

Serum ferritin concentration in sickle cell crisis. Serum ferritin, aspartate aminotransferase (AST), alkaline phosphatase and hydroxybutyrate dehydrogenase (HBD) were studied during 21 vaso-occlusive crises in 12 adults with sickle cell disease (11 SS, 1 S beta degrees). The patients comprised three groups: those who had been untransfused (4), those who had received occasional exchange transfusion in crisis (3), and those who had been multiply transfused (5). Serum ferritin concentrations (...) in crisis were compared with those of the steady state value. Rises in serum ferritin concentrations occurred in all crises in all groups. Although AST, alkaline phosphatase, and HBD rose, there was no correlation between these and log ferritin concentrations. The clinical impression was that the degree of rise in ferritin related to the severity of the particular crisis, and the above results showed that haemolysis and liver damage were not causally related to this rise. An estimate of serum ferritin

1986 Journal of Clinical Pathology

5707. Serum ferritin as indicator of iron responsive anaemia in patients with rheumatoid arthritis. Full Text available with Trip Pro

indicator of iron responsive anaemia, with a predictive value of 83%. Although high plasma transferrin and low mean cell volume showed similar predictive values, more patients with iron deficiency anaemia could be diagnosed by serum ferritin measurements than by other conventional blood tests. In contrast, the predictive value of serum ferritin above 60 micrograms/l was low (50%). The test was of no predictive value in non-anaemic patients. In patients with anaemia and active rheumatoid arthritis serum (...) Serum ferritin as indicator of iron responsive anaemia in patients with rheumatoid arthritis. In order to test the hypothesis that serum ferritin below 60 micrograms/l is a good indicator of iron deficiency in patients with rheumatoid arthritis peroral iron was given to 67 patients with active rheumatoid arthritis over a three month period. A rise in haemoglobin concentration was taken as evidence of iron responsive anaemia. In anaemic patients serum ferritin below 60 micrograms/l was a good

1986 Annals of the Rheumatic Diseases

5708. Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's disease Full Text available with Trip Pro

Percentage of glycosylated serum ferritin remains low throughout the course of adult onset Still's disease To determine the evolution of levels of total serum ferritin and percentage of the glycosylated form in patients with adult onset Still's disease (AOSD) at the time of diagnosis and during follow up.All patients with AOSD were tested at the time of diagnosis and during follow up. Total serum ferritin levels were analysed by immunoassay, and the percentage of glycosylated ferritin (...) was determined by methods using Sepharose-Con A.14 patients (eight women, six men) with AOSD were enrolled. At the time of diagnosis, mean (SD) age was 36 (16) years. Mean initial total serum ferritin was 6350 (1300) microg/l (normal <250 microg/l). The mean initial percentage of glycosylated ferritin was 14.7 (13)% (normal >50%). Mean follow up time was 37 (35) months. At the time of the last examination all patients were in remission except one, who presented a chronic articular form. Total serum ferritin

2000 Annals of the Rheumatic Diseases

5709. Evaluation of serum ferritin as a marker for adult Still's disease activity. Full Text available with Trip Pro

Evaluation of serum ferritin as a marker for adult Still's disease activity. Extremely high serum ferritin values (greater than 10,000 micrograms/l) were detected in two patients with adult Still's disease. The ferritin concentrations decreased to normal after adequate treatment. During a one year follow up ferritin concentration was helpful in monitoring disease activity and guiding decisions about treatment. Raised concentrations of soluble interleukin 2 receptors (sCD25) were also found (...) . Detection of ferritin values above 3000 micrograms/l should lead to the consideration of Still's disease when there is an acute febrile illness without evidence for bacterial or viral infections, serum ferritin being suitable for monitoring treatment.

1992 Annals of the Rheumatic Diseases

5710. Logarithmic quantitation model using serum ferritin to estimate iron overload in secondary haemochromatosis. Full Text available with Trip Pro

Logarithmic quantitation model using serum ferritin to estimate iron overload in secondary haemochromatosis. Nineteen children and adolescents receiving repeated transfusions and subcutaneous desferrioxamine treatment were investigated in an attempt to quantitate iron overload non-invasively. Before patients were started on desferrioxamine individual relationships were correlated for 12 to 36 months between transfused iron, absorbed iron estimated gastrointestinally, and increasing serum (...) ferritin concentrations. Patients with inflammation, increased liver enzymes, or haemolysis were excluded from analysis. The relationship between the variables could be described by a logarithmic regression curve (y = transfused iron [plus eventually gastrointestinally absorbed iron] = iron overload = a+b log [x = serum ferritin]) for each individual patient. All patients showed close correlation (R2) between x and y (median R2 of 0.909, 0.98, and 0.92 in thalassaemia, aplastic anaemia, and sickle cell

1996 Archives of Disease in Childhood

5711. The effect of iron treatment on serum ferritin concentrations and bone marrow stainable iron in iron deficient out-patients with gastritis, gastric ulcer and duodenal ulcer. (Abstract)

The effect of iron treatment on serum ferritin concentrations and bone marrow stainable iron in iron deficient out-patients with gastritis, gastric ulcer and duodenal ulcer. Serum ferritin concentrations and bone marrow stainable iron were determined in 122 adult out-patients (seventy males) with gastritis, gastric ulcer and duodenal ulcer. Half of the forty-four patients with iron deficiency (serum ferritin level below 20 micrograms/l) received peroral iron therapy (200 mg Fe++ daily). In most (...) of the treated patients serum ferritin levels increased and the amount of bone marrow stainable iron in half of them also increased. Measurement of body iron stores by serum ferritin determinations and restoration of low body iron stores in these patients is of practical importance.

1984 The Journal of international medical research Controlled trial quality: uncertain

5712. Effect of laparoscopic sterilization and insertion of Multiload Cu 250 and Progestasert IUDs on serum ferritin levels. (Abstract)

Effect of laparoscopic sterilization and insertion of Multiload Cu 250 and Progestasert IUDs on serum ferritin levels. Blood haemoglobin and serum ferritin levels were measured at the initial visit and 12 months following sterilization and IUD insertion. Ferritin levels were unaltered in Progestasert users after 12 months but haemoglobin values increased though not significantly. Ferritin levels fell in Multiload Cu 250 users and in sterilized women; haemoglobin levels were also observed (...) acceptability. Menstrual blood loss studies may help explain why anaemia develops after sterilization.

1983 Contraception Controlled trial quality: uncertain

5713. Impact of anaemia prophylaxis in pregnancy on maternal haemoglobin, serum ferritin & birth weight. (Abstract)

Impact of anaemia prophylaxis in pregnancy on maternal haemoglobin, serum ferritin & birth weight. A total of 418 pregnant women at 16-24 wk of gestation, from six subcentres of a rural block of Varanasi district were selected. Pregnant women (137 of 215) from 3 subcentres received the supplementation of 60 mg elemental iron as ferrous sulphate combined with 500 micrograms folic acid, daily for 100 days (study group) and 123 (of 203) pregnant women from the other 3 subcentres without (...) supplementation (control group) could be evaluated for their pregnancy outcome. The haemoglobin and serum ferritin levels increased significantly in the study group. In the latter, the mean birth weight was 2.88 +/- 0.41 kg with low birth weight incidence of 20.4 per cent as compared to the control figures of 2.59 +/- 0.34 kg and 37.9 per cent respectively. The incidence of low birth weight was further reduced to 12.1 per cent if the supplementation could be started by 16-19 wk of gestation.

1991 The Indian journal of medical research Controlled trial quality: uncertain

5714. Effects of low-dose iron supplementation in women with low serum ferritin concentration. (Abstract)

group (27 mg iron x day-1, n = 19). The supplement consisted of 11% heme and 89% inorganic iron. In FE-27, serum ferritin increased from (mean, 95% confidence interval) 11.8 (9.7; 14.4) to 25.3 (18.6; 34.4) micrograms x l-1 in 1 month, and remained stable after that (ANOVA: group effect, P = 0.0003). In both FE-9 and FE-27, blood haemoglobin levels increased from 136 (132; 140) to 142 (139; 145) g x l-1 in 1 month, remaining constant after that (group effect, P = 0.001). Hence, the 27 mg daily dose (...) Effects of low-dose iron supplementation in women with low serum ferritin concentration. We studied effects of dose and treatment duration during low-dose iron supplementation in premenopausal, non-pregnant women, with initial serum ferritin and haemoglobin concentrations < 20 micrograms x l-1 and > or = 120 g x l-1, respectively. The study was randomized, double-blind and placebo-controlled. Three groups completed a 6-month study: placebo (n = 27), FE-9 (9 mg iron x day-1, n = 18) and FE-27

1994 European journal of clinical nutrition Controlled trial quality: predicted high

5715. Iron status in young Danes. Evaluation by serum ferritin and haemoglobin in a population survey of 634 individuals aged 14-23 yr. (Abstract)

Iron status in young Danes. Evaluation by serum ferritin and haemoglobin in a population survey of 634 individuals aged 14-23 yr. Iron status was assessed by serum ferritin and haemoglobin in a population survey comprising 634 randomly selected urban Danes (312 males, 322 females) 14-23 yr old. At all ages, males had significantly higher serum ferritin and haemoglobin values than females. Males: median serum ferritin displayed a steady increase with age from 33 to 109 micrograms/l (rs = 0.53, p (...) < 0.0001). The prevalence of absent mobilizable body iron stores (serum ferritin < 13 micrograms/l) was 3.5% at 16-17 yr of age, gradually declining to 0% at 22-23 yr. None of the males had iron deficiency anaemia (serum ferritin < 13 micrograms/l and haemoglobin < 129 g/l). Females: median ferritin values displayed a slight increase with age from 28 to 39 micrograms/l (rs = 0.19, p < 0.001). The prevalence of absent iron stores was 12.5% at 16-17 yr of age, declining to 6.6% at 22-23 yr

1997 European journal of haematology

5716. Serum ferritin and heart disease: the effect of moderate exercise on stored iron levels in postmenopausal women. (Abstract)

Serum ferritin and heart disease: the effect of moderate exercise on stored iron levels in postmenopausal women. To determine the effect of a moderate exercise regimen on stored iron as measured by serum ferritin in previously sedentary postmenopausal women.Randomized assignment to one of three groups: a five day/week walking group (five-day group, n = 27); a three day/week walking group (three-day group, n = 27) or a sedentary group (control group, n = 25).Community-based intervention.Women (...) are reported for 56 subjects (five-day group, n = 17; three-day group, n = 19; control group, n = 20) who completed the study. Their mean age was 61.3 +/- 5.8 years.The five-day group and the three-day group walked an average of 279 +/- 20 and 171 +/- 7 mins/week, respectively. Participants were counselled not to change their dietary intake.Following 24 weeks of walking, mean serum ferritin decreased significantly in the five-day group (P < 0.03), but not in the three-day group (P < 0.09) compared

1996 The Canadian journal of cardiology Controlled trial quality: uncertain

5717. Detection of a glycosylated subunit in human serum ferritin. Full Text available with Trip Pro

Detection of a glycosylated subunit in human serum ferritin. Ferritin was purified from the serum of two patients with idiopathic haemochromatosis. The protein contained three types of subunit--the H and L subunits of tissue ferritins (although only a trace of H could be detected) and a third subunit, 'G', with the highest apparent molecular weight. Only the 'G' subunit band stained for carbohydrate, indicating that a proportion of the subunits of human serum ferritin are glycosylated. Although (...) serum was obtained from patients with idiopathic haemochromatosis, it is probable that the 'G' subunit is a component of normal serum ferritin.

1981 Biochemical Journal

5718. Serum ferritin in normal individuals and in patients with malignant lymphoma and chronic renal failure measured with seven different commercial immunoassay techniques. Full Text available with Trip Pro

Serum ferritin in normal individuals and in patients with malignant lymphoma and chronic renal failure measured with seven different commercial immunoassay techniques. A comparison of serum ferritin determination by seven different commercial immunoassay techniques gave mean coefficients of variation of 57% for normal individuals, 41 . 4% for patients with malignant lymphoma and 43 . 1% for patients with chronic renal failure. One of the immunoradiometric assays gave consistently higher serum (...) ferritin values in both normal and patient groups; mean values were increased (greater than 100% for normal males, greater than 50% for normal females) with respect to the other assays. Underestimation of serum ferritin by an enzyme-linked immunosorbent assay was also evident. Results were affected by storage conditions, but not by dilution of samples, in two kits. Solutions of ferritin purified from normal and malignant human and mouse tissues, and lymphoma isoferritins, were used for reference

1982 Journal of Clinical Pathology

5719. Serum ferritin concentration and bone marrow iron stores Full Text available with Trip Pro

Serum ferritin concentration and bone marrow iron stores 20313447 2010 06 28 2018 11 13 0008-4409 122 12 1980 Jun 21 Canadian Medical Association journal Can Med Assoc J Serum ferritin concentration and bone marrow iron stores. 1355-6 Gimferrer E E Ayats R R Pujol-Moix N N Baiget M M eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 2010 3 24 6 0 1980 6 21 0 0 1980 6 21 0 1 ppublish 20313447 PMC1801915 Can Med Assoc J. 1979 May 19;120(10):1204, 1207 445259 Can Med Assoc J. 1978 Apr

1980 Canadian Medical Association Journal

5720. Bilateral cataract and high serum ferritin: a new dominant genetic disorder? Full Text available with Trip Pro

Bilateral cataract and high serum ferritin: a new dominant genetic disorder? 8558554 1996 02 28 2018 11 13 0022-2593 32 10 1995 Oct Journal of medical genetics J. Med. Genet. Bilateral cataract and high serum ferritin: a new dominant genetic disorder? 778-9 Bonneau D D Service de Pédiatrie et Génétique, CHU de Poitiers, France. Winter-Fuseau I I Loiseau M N MN Amati P P Berthier M M Oriot D D Beaumont C C eng Case Reports Journal Article England J Med Genet 2985087R 0022-2593 9007-73-2 (...) Ferritins IM Cataract blood genetics Child Female Ferritins blood genetics Genes, Dominant Humans Male Metabolism, Inborn Errors genetics Pedigree 1995 10 1 1995 10 1 0 1 1995 10 1 0 0 ppublish 8558554 PMC1051699 N Engl J Med. 1975 May 1;292(18):951-6 1090831 Somat Cell Mol Genet. 1994 Jan;20(1):67-9 8197479 Hum Genet. 1985;69(4):371-4 3857215 Clin Haematol. 1982 Jun;11(2):275-307 6176386

1995 Journal of Medical Genetics

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