How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

5,976 results for

Serum Ferritin

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

5621. Recombinant human erythropoietin as an adjunct to radiation therapy and cisplatin for stage IIB-IVA carcinoma of the cervix: a Southwest Oncology Group study. (Abstract)

, and 11.8 +/- 2.2 g/dl at the end of chemoradiotherapy. The target Hgb level of 12.5 g/dl was achieved in 40% of patients (95% CI 26-56%) by the midpoint of Chemoradiotheraphy. Change in Hgb was associated with baseline serum iron (P = 0.008) and transferrin saturation (P = 0.05) levels, but not with baseline Hgb or serum ferritin, or patient age. Seven patients developed deep vein thrombosis. Two-year progression-free survival (PFS) was 43% and overall survival (OS) was 51%. Survival was significantly

2004 Gynecologic Oncology

5622. Response predicting factors to recombinant human erythropoietin in cancer patients undergoing platinum-based chemotherapy. Full Text available with Trip Pro

-alpha was administered subcutaneously three times a week at a dose of 150 IU/kg. Ninety patients were examined.Response was defined as an increase in Hb of at least 2 g/dL during the treatment period. The response rate was 63.3%. The following data were compared between responders and nonresponders at the onset of treatment and after 2 and 4 weeks of epoetin therapy: Hb, reticulocytes, serum iron, ferritin, transferrin, transferrin saturation index, and endogenous erythropoietin levels. At baseline

2002 Cancer

5623. Iron deficiency in adolescent female dancers. Full Text available with Trip Pro

Iron deficiency in adolescent female dancers. The iron balance of 25 adolescent dancers and 23 control females of the same age were studied. The concentrations of fasting blood haemoglobin, serum iron, serum transferrin and serum ferritin were determined. Iron supplementation (ferrous sulphate corresponding to 100 mg of elemental iron per day) was instigated if body iron stores were low (serum ferritin less than 30 micrograms.l-1). Blood samples were drawn again after ten weeks. Low haemoglobin (...) concentration (blood haemoglobin less than 125 g.l-1) was more prevalent among dancers than among control subjects. Reduced iron stores as well as completely absent iron stores (serum ferritin concentration less than 12 micrograms.l-1) were equally common in both groups (25% of the subjects). Iron supplementation reduced the number of anaemic girls from 16 to 4 and the highly significant difference in haemoglobin level between the treated and untreated groups disappeared. Ten weeks of iron therapy

1988 British Journal of Sports Medicine

5624. Evaluation of iron metabolism indices and their relation with physical work capacity in athletes. Full Text available with Trip Pro

Evaluation of iron metabolism indices and their relation with physical work capacity in athletes. To evaluate the relation between iron status and physical working capacity, and to assess the effect of oral iron treatment on these variables, in athletes with borderline iron status.Blood haemoglobin (Hb), packed cell volume (PCV), red blood cell count (RBC), serum iron, total iron binding capacity (TIBC), and ferritin determinations were compared in 71 male and 18 female athletes participating (...) in various sports and in matched male (n = 11) and female (n = 8) controls. The first aim was to assess the relations between these variables and performance in a physical work capacity test (PWC170). Oral iron treatment (175-350 mg ferrous fumarate daily) was provided for three weeks to six male and five female athletes with borderline Hb concentrations, to determine the effects of such treatment on both iron status and performance.Among females, handball players had the lowest serum ferritin

1996 British Journal of Sports Medicine

5625. Changes in haematological parameters and iron metabolism associated with a 1600 kilometre ultramarathon Full Text available with Trip Pro

, total red cell count, mean red cell volume, mean red cell haemoglobin, total white cell count and differential, platelets, reticulocytes, iron, ferritin, total iron binding capacity, percentage transferrin saturation, haptoglobin, and bilirubin and corrected for changes in plasma volume.The following variables decreased during the event (p < 0.05): haemoglobin, packed cell volume, mean red cell volume, percentage lymphocytes, percentage monocytes, serum iron, total iron binding capacity (...) Changes in haematological parameters and iron metabolism associated with a 1600 kilometre ultramarathon To investigate haematological variations and iron related changes in the serum of participants in a 1600 kilometre ultramarathon run.Seven male and two female participants in a 1600 km foot race.Blood samples were obtained from the participants before, after four and 11 days of running, and at the end of the event. Samples were analysed by standard methods for haemoglobin, packed cell volume

1999 British Journal of Sports Medicine

5626. Mutations in the hereditary haemochromatosis gene HFE in professional endurance athletes Full Text available with Trip Pro

responsible for hereditary haemochromatosis) in endurance athletes.Basal concentrations of iron, ferritin, and transferrin and transferrin saturation were determined in the period before competition in 65 highly trained athletes. Possible mutations in the HFE gene were evaluated in each subject by extracting genomic DNA from peripheral blood. The restriction enzymes SnaBI and BclI were used to detect the mutations 845G-->A (C282Y) and 187C-->G (H63D).Our findings indicate a high prevalence of HFE gene (...) mutations in this population (49.2%) compared with sedentary controls (33.5%). No association was detected in the athletes between mutations and blood iron markers.The findings support the need to assess regularly iron stores in elite endurance athletes.

2004 British Journal of Sports Medicine

5627. The acute phase response and exercise: court and field sports Full Text available with Trip Pro

The acute phase response and exercise: court and field sports To determine the presence or absence of an acute phase response after training for court and field sports.All members of the Australian women's soccer team (n = 18) and all members of the Australian Institute of Sport netball team (n = 14).Twelve acute phase reactants (white blood cell count, neutrophil count, platelet count, serum iron, ferritin, and transferrin, percentage transferrin saturation, alpha(1) antitrypsin

2001 British Journal of Sports Medicine

5628. Effects of exercise on soluble transferrin receptor and other variables of the iron status Full Text available with Trip Pro

Effects of exercise on soluble transferrin receptor and other variables of the iron status Soluble transferrin receptor (sTfr) is a new marker of iron status and erythropoietic activity. It has been included in multivariable blood testing models for the detection of performance enhancing erythropoietin misuse in sport.To evaluate the effect of different types and volumes of physical activity on sTfr concentration, variables of iron status (ferritin, transferrin, iron, and protein (...) volume were analysed in venous blood samples before and after exercise. Changes in blood and plasma volume were estimated.sTfr levels were slightly increased in trained and untrained subjects immediately after test A. Test B and aerobic exercise had no significant effect on sTfr. Ferritin levels were increased after the laboratory tests for trained and untrained subjects and after prolonged aerobic exercise in male cyclists. Transferrin was increased significantly in trained and untrained subjects

2002 British Journal of Sports Medicine

5629. The response of trained athletes to six weeks of endurance training in hypoxia or normoxia. (Abstract)

%) and in maximal blood lactate concentration (from 7.0 to 9.1 mM) in HG only. Ferritin levels were decreased from 67.4 +/- 16.3 to 42.2 +/- 9.5 microg/l (p < 0.05) in the HG and from 54.3 +/- 6.9 to 31.4+/- 8.0 microg/l (p = 0.17) in the NG. Reticulocytes were significantly increased in both groups by a factor of two. In conclusion, the integration of six weeks of high intensity endurance training did not lead to improved performance in endurance trained athletes whether this training was carried out

2003 International Journal of Sports Medicine Controlled trial quality: uncertain

5630. ferritin

ferritin ferritin - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search ferritin Ferritin is an iron-protein complex found in most tissues, but particularly the bone marrow and reticuloendothelial system. Clinically, its importance is: as an acute phase protein as a non-specific index of liver disease its close relationship to body stores of iron. Thus a low serum ferritin implies iron deficiency. Conversely, high ferritin can (...) imply iron overload states. However, given the first two points in the list, ferritin levels must be interpreted in the light of ongoing inflammation and liver disease. Notes (1): whilst low serum ferritin (SF) is a sensitive and specific indicator of low total body iron stores, elevated SF is sensitive but very nonspecific for iron overload a normal SF rules out iron overload raised SF only 10% of cases of elevated SF are due to iron overload - chronic alcohol consumption, metabolic syndrome

2010 GP Notebook

5631. Screening blood donors for hereditary hemochromatosis: decision analysis model comparing genotyping to phenotyping

Screening blood donors for hereditary hemochromatosis: decision analysis model comparing genotyping to phenotyping Screening blood donors for hereditary hemochromatosis: decision analysis model comparing genotyping to phenotyping Screening blood donors for hereditary hemochromatosis: decision analysis model comparing genotyping to phenotyping Adams P C, Valberg L S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Screening blood donors for hereditary hemochromatosis. Type of intervention Screening. Economic study type Cost-utility analysis. Study population The study population was a hypothetical cohort of 10,000 voluntary blood donors and 50 siblings of the identified homozygotes. Setting Hospital and primary care. The study

1999 NHS Economic Evaluation Database.

5632. Screening blood donors for hereditary hemochromatosis: decision analysis model based on a 30-year database

and a positive predictive value of 86%. The serum percentage TS test combined with serum ferritin has a sensitivity of 0.94 and a specificity of 0.86, respectively.22.1 donors with high TS and serum ferritin levels have a diagnostic percutaneous liver biopsy performed with hepatic iron determination. 90% of blood donors have positive screening results and consent to liver biopsy. The probability of intraperitoneal haemorrhage requiring transfusion is 0.002. The probability of blood donors dying from liver (...) findings from the database. Modelling A decision tree was constructed to estimate costs and benefits. Outcomes assessed in the review The main outcomes assessed in the review were prevalence, symptom onset, symptom-specific survival, penetration of disease, sensitivity and specificity of transferrin saturation (TS), serum ferritin levels, and hepatic iron index. Study designs and other criteria for inclusion in the review Not stated. Sources searched to identify primary studies Not stated. Criteria

1995 NHS Economic Evaluation Database.

5633. Cost-effectiveness impact of iron dextran on hemodialysis patients' use of epoetin alfa and blood

, and transferrin saturation greater than 20%, initiate iron dextran protocol; for hematocrit below 30%, ferritin concentration over 100ng/mL, and transferrin saturation above 20%, increase dosage by 50% to a maximum of 10,000 units three times a week. Before the initiation of the iron dextran protocol at the end of the six-month baseline period, iron dextran was administered randomly at doses ranging from a total of 100 to 500mg. Blood prescribing was at the nephrologists' discretion throughout the study (...) . Analysis of effectiveness The principle used in the analysis of effectiveness appears to have been treatment completers only. The primary outcome measure was success rate. Successful treatment was defined as a hematocrit of 33-36%, a transferrin saturation above 10%, a ferritin concentration of more than 100ng/mL, and no blood use except for acute blood loss. The following clinical variables were also reported: ferritin level, transferrin saturation, hematocrit, number of units of blood, epoetin alfa

1998 NHS Economic Evaluation Database.

5634. serum ferritin

serum ferritin serum ferritin - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search serum ferritin Ferritin is an iron-protein complex found in most tissues, but particularly the bone marrow and reticuloendothelial system. Clinically, its importance is: as an acute phase protein as a non-specific index of liver disease its close relationship to body stores of iron. Thus a low serum ferritin implies iron deficiency. Conversely (...) , high ferritin can imply iron overload states. However, given the first two points in the list, ferritin levels must be interpreted in the light of ongoing inflammation and liver disease. Notes (1): whilst low serum ferritin (SF) is a sensitive and specific indicator of low total body iron stores, elevated SF is sensitive but very nonspecific for iron overload a normal SF rules out iron overload raised SF only 10% of cases of elevated SF are due to iron overload - chronic alcohol consumption

2010 GP Notebook

5635. Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy?

any other indications for colonoscopy including positive fecal occult blood testing, change in bowel habits, personal or family history of colon cancer, FAP, HNPCC, or IBD. For inclusion, a ferritin level must have been checked in the eight weeks preceding colonoscopy. Four-hundred and twenty four patients were included and were divided into three groups based on ferritin levels: 1) <50ng/dL (iron-deficient, N=254), 2) 51-100ng/dL (low normal, N=55), and 3) >100ng/dL (normal, N=115). The primary (...) Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy? Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy? – Clinical Correlations Search Should patients with Anemia and a Normal Ferritin Undergo Colonoscopy? February 16, 2007 3 min read Commentary By: Joshua Olstein PGY-3 Second only to lung cancer, colon cancer claimed an estimated 55,000 lives in the United States in 2006. In an effort to reduce colon cancer morbidity and mortality, multiple screening tests

2007 Clinical Correlations

5636. I have a patient (80 yr female) who has a serum ferrritin of 262 (nr 13-150) what investigations are needed?

on ‘Interpretation of an elevated serum ferritin’ [1]. This articles starts with the statement: “The interpretation of an elevated serum ferritin requires consideration of several separate disease categories. These come under the broad headings of: - Iron overload - Acute inflammatory conditions - Liver disease - Alcohol excess” This further expands the potential causes of: “ Causes of iron overload Primary -Hereditary haemochromatosis -Hereditary aceruloplasminemia (Wilson’s disease) Secondary -Transfusion (...) overload -Excess dietary iron -Porphyria cutanea tarda -Ineffective erythropoiesis (Sideroblastic anaemia, Thalassemia) Causes of high serum ferritin without iron overload -Liver disease – non-alcoholic hepatitic steatosis (NASH)* or viral hepatitis (B/C?G) -Alcohol excess -Chronic inflammatory conditions – Rheumatoid arthritis, inflammatory bowel disease – Bacterial infections -Malignancy especially haematological -Thyrotoxicosis -Familial hyperferritinemia and cataract syndrome” The document

2006 TRIP Answers

5637. Description of Iron Status in Blood Donors

100 mg A: 100 mg pr day in 8 days Outcome Measures Go to Primary Outcome Measures : Iron status [ Time Frame: april 2008 ] Secondary Outcome Measures : Hemoglobin and serum ferritin [ Time Frame: april 2008 ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact (...) Description of Iron Status in Blood Donors Description of Iron Status in Blood Donors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Description of Iron Status in Blood Donors The safety and scientific

2008 Clinical Trials

5638. Comparing prevalence of Iron Deficiency Anemia and Beta Thalassemia Trait in microcytic and non-microcytic blood donors: suggested algorithm for donor screening Full Text available with Trip Pro

subjected to Ferritin and HbA2 determination. Subsequently, an additional 51, age-and-sex matched non-microcytic donor samples were selected to serve as controls. These were subjected to the same tests.The prevalence of microcytosis was 5.4% (50/925). Among the microcytic donors, 52% were IDA, 36% BTT, 8% both, and 4% none. In case of non-microcytic donors 29.4% were IDA, 3.9% BTT, and 66.7% none.The study revealed a high prevalence of IDA and BTT in blood donors and a higher probability of finding (...) these in the microcytic samples. This prompted authors to suggest an algorithm for screening of blood donors for IDA and BTT. The algorithm recommends doing an hemogram on all donor samples, routinely. Ferritin could be done only in microcytic samples. At levels lower than15 ng/ml, it is diagnosed as IDA, and therefore, HPLC is performed only for non-IDA samples with Ferritin levels higher than 15 ng/ml. By employing this algorithm, a substantial number of IDA and BTT could be diagnosed while keeping the number

2009 Asian journal of transfusion science

5639. Iron status of regular voluntary blood donors Full Text available with Trip Pro

automatic haematology analyzer, serum iron and total iron-binding capacity (TIBC) by biochemical methods, ferritin using ELISA kits and transferrin using immunoturbidometry kits. Iron/TIBC ratio x 100 gave percentage of transferrin saturation value.Statistical evaluation was done by mean, standard deviation, pair t-test, chi(2) and anova (F-test).Preliminary analysis revealed that there was no significant difference in the iron profile of vegetarian and non-vegetarian subjects or controls and the donors (...) Iron status of regular voluntary blood donors Our blood bank is a regional blood transfusion centre, which accepts blood only from voluntary donors.The aim is to study iron status of regular voluntary donors who donated their blood at least twice in a year.Prior to blood donation, blood samples of 220 male and 30 female voluntary donors were collected. Control included 100 each male and female healthy individuals in the 18- to 60-year age group, who never donated blood and did not have any

2008 Asian journal of transfusion science

5640. MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions.

MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions. MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00629291 Recruitment Status : Completed First Posted : March 5

2008 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>