How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

101,287 results for

Serum Creatinine

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Could late measurement of serum creatinine be missed for patients without early increase in serum creatinine following coronary angiography? (PubMed)

Could late measurement of serum creatinine be missed for patients without early increase in serum creatinine following coronary angiography? Most patients are discharged early (within 24 hours) after coronary angiography (CAG) and may miss identification the late (24-48 hours) increase in serum creatinine (SCr), whose characteristics and prognosis have been less intensively investigated.We prospectively recruited 3065 consecutive patients with SCr measurement, including only1344 patients

Full Text available with Trip Pro

2017 Medicine

2. Methodological Study of Vancomycin Dosing in Elderly Patients Using Actual Serum Creatinine Versus Rounded Serum Creatinine (PubMed)

Methodological Study of Vancomycin Dosing in Elderly Patients Using Actual Serum Creatinine Versus Rounded Serum Creatinine The practice of intentional rounding up of serum creatinine (SCr) in elderly patients with low measured values can lead to an underestimation of creatinine clearance and subsequent inaccurate dosing of medications. Thus, the purpose of this study was to evaluate the accuracy of vancomycin dose calculations for patients aged ≥65 years using an SCr rounded up to 1 mg/dL

Full Text available with Trip Pro

2017 Drugs in R&D

3. Observational study: Prescribing of metformin based on estimated GFR rather than serum creatinine expands the eligible population and is likely safe

Observational study: Prescribing of metformin based on estimated GFR rather than serum creatinine expands the eligible population and is likely safe Prescribing of metformin based on estimated GFR rather than serum creatinine expands the eligible population and is likely safe | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Prescribing of metformin based on estimated GFR rather than serum creatinine expands the eligible population

2016 Evidence-Based Medicine (Requires free registration)

4. Reference intervals for serum cystatin C and serum creatinine in an adult sub-Saharan African population. (PubMed)

Reference intervals for serum cystatin C and serum creatinine in an adult sub-Saharan African population. Serum cystatin C (SCysC) and serum creatinine (SCr) are two biomarkers used in common practice to estimate the glomerular filtration rate (GFR). For SCysC and SCr to be used in a given population, normal values need to be determined to better assess patients. This study aimed to determine SCysC and SCr reference intervals (RIs) in a Cameroonian adult population and factors susceptible (...) biomarkers' values across all quantile regression models while age and body surface area (BSA) influenced them inconsistently.This study has determined serum cystatin C and serum creatinine reference intervals in an adult Cameroonian population, whose interpretations might take into account the patient's sex and to a certain extent, his/her age and/or BSA.

Full Text available with Trip Pro

2019 BMC Clinical Pathology

5. Development of a novel linear model for predicting recipient's post-transplant serum creatinine level after living donor kidney transplantation: A multicenter cross-validation study. (PubMed)

Development of a novel linear model for predicting recipient's post-transplant serum creatinine level after living donor kidney transplantation: A multicenter cross-validation study. This study was designed to develop and cross-validate a statistical model for predicting post-transplant serum creatinine of living donor kidney transplantation.Adult recipients of living donor kidney transplantation from August 2012 to October 2017 at Samsung Medical Center (SMC) and Seoul National University (...) Hospital (SNUH) with normal post-transplant protocol biopsy were included for modelling. Demographic data including recipient and donor's sex, age, body measurements and comorbidities, pre-transplant donor serum creatinine, graft weight, post-transplant recipient serum creatinine and the result of protocol biopsy were collected. Multivariate linear regression analysis was performed for developing the model based on SMC cohort. Internal validation was performed using leave-one-out cross-validation

Full Text available with Trip Pro

2019 PLoS ONE

6. Serum creatinine and estimated glomerular filtration rates in HIV positive and negative adults in Ethiopia. (PubMed)

Serum creatinine and estimated glomerular filtration rates in HIV positive and negative adults in Ethiopia. Glomerular filtration rate estimating equations using serum creatinine are not validated in most African settings. We compared serum creatinine and estimated glomerular filtration rate (eGFR) in HIV positive and negative adults and assessed the performance of eGFR equations ((Cockcroft and Gault (CG), Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology (...) Collaboration (CKD-EPI)) compared to 24-hour creatinine clearance in HIV positive adults.Data were collected on demographic, anthropometric, body composition, clinical parameters and serum creatinine in HIV positive and negative adults. 24-hour urine was collected from some of the HIV positive adults who volunteered. Bias was calculated as mean difference between 24-hr creatinine clearance and eGFR (eGFR- 24 hour creatinine clearance) and the accuracy of each eGFR equation was calculated as the percentage

2019 PLoS ONE

7. Acute Kidney Injury Ascertainment Is Affected by the Use of First Inpatient Versus Outpatient Baseline Serum Creatinine (PubMed)

Acute Kidney Injury Ascertainment Is Affected by the Use of First Inpatient Versus Outpatient Baseline Serum Creatinine 29340333 2018 11 13 2468-0249 3 1 2018 Jan Kidney international reports Kidney Int Rep Acute Kidney Injury Ascertainment Is Affected by the Use of First Inpatient Versus Outpatient Baseline Serum Creatinine. 211-215 10.1016/j.ekir.2017.08.011 Liu Kathleen D KD Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California

Full Text available with Trip Pro

2017 Kidney international reports

8. Creatinine generation from kinetic modeling with or without postdialysis serum creatinine measurement: results from the HEMO study (PubMed)

Creatinine generation from kinetic modeling with or without postdialysis serum creatinine measurement: results from the HEMO study A convenient method to estimate the creatinine generation rate and measures of creatinine clearance in hemodialysis patients using formal kinetic modeling and standard pre- and postdialysis blood samples has not been described.We used data from 366 dialysis sessions characterized during follow-up month 4 of the HEMO study, during which cross-dialyzer clearances (...) the creatinine generation rate using the urea distribution volume and urea dialyzer clearance without use of the postdialysis serum creatinine measurement gave results for creatinine generation rate [1187 (SD 475) mg/day; that closely matched the value calculated using the formally modeled value, R2 = 0.971].Our analysis confirms previous findings of similar distribution volumes for creatinine and urea. After taking extra-renal clearance into consideration, the creatinine generation rate in dialysis patients

Full Text available with Trip Pro

2017 Nephrology Dialysis Transplantation

9. Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial. (PubMed)

Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial. Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr

2018 Iranian journal of pharmaceutical research : IJPR

10. Creatinine-based definitions: from baseline creatinine to serum creatinine adjustment in intensive care (PubMed)

Creatinine-based definitions: from baseline creatinine to serum creatinine adjustment in intensive care This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.

Full Text available with Trip Pro

2016 Critical Care

11. High Loading Dose of Atorvastatin for the Prevention of Serum Creatinine and Cystatin C-Based Contrast-Induced Nephropathy Following Percutaneous Coronary Intervention. (PubMed)

High Loading Dose of Atorvastatin for the Prevention of Serum Creatinine and Cystatin C-Based Contrast-Induced Nephropathy Following Percutaneous Coronary Intervention. The aim of this study is to assess the efficacy of high-dose atorvastatin on the prevention of contrast-induced nephropathy (CIN) in patients with acute coronary syndrome (ACS) undergoing percutaneous intervention and observe the incidence of cystatin C (CyC)-based CIN. A total of 496 patients with ACS were randomly assigned (...) to either the control group (247 patients receiving conventional dose atorvastatin 10 mg daily from 1 day before to 3 days after contrast administration) or the high-dose atorvastatin group (249 patients receiving atorvastatin 40 mg daily for the same perioperative period). The baseline characteristics of the 2 groups were similar. The primary end point of serum creatinine (SCr)-based CIN occurred in 31 patients in the control group and 16 patients in the high-dose atorvastatin group (12.6% vs 6.4%; P

2019 Angiology

12. Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study. (PubMed)

Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study. Objective To examine long term cardiorenal outcomes associated with increased concentrations of creatinine after the start of angiotensin converting enzyme inhibitor/angiotensin receptor blocker treatment.Design Population based cohort study using electronic health records from the Clinical Practice Research Datalink and Hospital Episode Statistics.Setting UK primary care, 1997-2014 (...) .Participants Patients starting treatment with angiotensin converting enzyme inhibitors or angiotensin receptor blockers (n=122 363).Main outcome measures Poisson regression was used to compare rates of end stage renal disease, myocardial infarction, heart failure, and death among patients with creatinine increases of 30% or more after starting treatment against those without such increases, and for each 10% increase in creatinine. Analyses were adjusted for age, sex, calendar period, socioeconomic status

Full Text available with Trip Pro

2017 BMJ

13. Acute Increases in Serum Creatinine After Starting Angiotensin-Converting Enzyme Inhibitor-Based Therapy and Effects of its Continuation on Major Clinical Outcomes in Type 2 Diabetes Mellitus. (PubMed)

Acute Increases in Serum Creatinine After Starting Angiotensin-Converting Enzyme Inhibitor-Based Therapy and Effects of its Continuation on Major Clinical Outcomes in Type 2 Diabetes Mellitus. Discontinuation of angiotensin-converting enzyme (ACE) inhibitor is recommended if patients experience ≥30% acute increase in serum creatinine after starting this therapy. However, the long-term effects of its continuation or discontinuation on major clinical outcomes after increases in serum creatinine (...) are unclear. In the ADVANCE trial (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation), 11 140 diabetes mellitus patients were randomly assigned to perindopril-indapamide or placebo after a 6-week active run-in period. The current study included 11 066 participants with 2 serum creatinine measurements recorded before and during the active run-in period (3 weeks apart). Acute increase in creatinine was determined using these 2 measurements and classified

Full Text available with Trip Pro

2019 Hypertension

14. Effectiveness of whey protein supplements on the serum levels of amino acid, creatinine kinase and myoglobin of athletes: a systematic review and meta-analysis. (PubMed)

Effectiveness of whey protein supplements on the serum levels of amino acid, creatinine kinase and myoglobin of athletes: a systematic review and meta-analysis. Consuming whey protein supplements, along with physiotherapy and psychotherapy, have been recognised in sports performance. Whey protein supplements (WPS) is one of the commonly used supplements as ergogenic aids for athletes to enhance their muscle performance and recovery during sport-related injuries. The purpose of this systematic (...) review is to investigate the effectiveness of WPS over the blood biochemistry mainly amino acids, creatinine kinase and myoglobin which influence performance and recovery among athletes.A comprehensive literature search was conducted to identify randomised control trials (RCTs) and non-RCTs that investigated the effectiveness of WPS on amino acids, creatinine kinase and myoglobin among athletes. Risk of Bias in Non-Randomised Studies of Interventions tool (ROBINS-I) and Cochrane Risk of Bias

Full Text available with Trip Pro

2019 Systematic reviews

15. The relationship of preoperative estimated glomerular filtration rate and outcomes after cardiovascular surgery in patients with normal serum creatinine: a retrospective cohort study. (PubMed)

The relationship of preoperative estimated glomerular filtration rate and outcomes after cardiovascular surgery in patients with normal serum creatinine: a retrospective cohort study. Although serum creatinine concentration has been traditionally used as an index of renal function in clinical practice, it is considered relatively inaccurate, especially in patients with mild renal dysfunction. This study investigated the usefulness of preoperative estimated glomerular filtration rate (eGFR (...) ) in predicting complications after cardiovascular surgery in patients with normal serum creatinine concentrations.This study included 2208 adults undergoing elective cardiovascular surgery. Preoperative eGFR was calculated using Chronic Kidney Disease Epidemiology Collaboration equations. The relationships between preoperative eGFR and 90 day postoperative composite major complications were analyzed, including 90 day all-cause mortality, major adverse cardiac and cerebrovascular events, severe acute kidney

Full Text available with Trip Pro

2019 BMC Anesthesiology

16. A novel simple experimental model for low-osmolar contrast-induced acute kidney injury using different definitions based on the levels of serum creatinine and cystatin C. (PubMed)

A novel simple experimental model for low-osmolar contrast-induced acute kidney injury using different definitions based on the levels of serum creatinine and cystatin C. It remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans.Fifty Sprague-Dawley rats were divided into five groups of 10 rats each: (1) sham group (normal saline [NS] + NS); (2) NS plus low osmolality contrast medium (CM15) (NS (...)  + CM15); (3) furosemide (FM) plus NS (FM + NS); (4) FM + CM10; and (5) FM + CM15.We measured the levels of serum creatinine (SCr), cystatin C (cys-C) and histopathological scores of kidney tissues.SCr level in the FM + CM15 group were significantly increased after CM exposure compared with baseline levels (32.9 ± 4.57 vs. 158.7 ± 14.48 μmol/L, p < 0.001). Minor changes were found about the SCr levels between the pre- and post-exposure CM or NS treatment in the other groups. Additionally, the cys-C

2019 BMC Nephrology

17. Serum NGAL and Cystatin C Comparison With Urinary Albumin-to-Creatinine Ratio and Inflammatory Biomarkers as Early Predictors of Renal Dysfunction in Patients With Type 2 Diabetes (PubMed)

Serum NGAL and Cystatin C Comparison With Urinary Albumin-to-Creatinine Ratio and Inflammatory Biomarkers as Early Predictors of Renal Dysfunction in Patients With Type 2 Diabetes Diabetic nephropathy is associated with specific histological changes. Early detection of poor glomerular and tubular function can be achieved with biomarkers of diabetes. The aim of this study was to evaluate the accuracy of kidney dysfunction biomarkers in type 2 diabetes (T2D).Patients with T2D were grouped (...) in T2D.Ninety patients with T2D were chosen. CysC was positively correlated with creatinine (P < 0.001), estimated glomerular filtration rate (P < 0.001), and urinary beta-trace protein (P = 0.01). The area under the curve was 0.635 for CysC, 0.621 for serum neutrophil gelatinase-associated lipocalin, and 0.660 for the albumin-to-creatinine ratio. A crude logistic regression model showed a positive association between serum CysC (P = 0.01) and serum neutrophil gelatinase-associated lipocalin (P < 0.001

Full Text available with Trip Pro

2016 Kidney international reports

18. Serum concentrations of symmetric dimethylarginine and creatinine in cats with kidney stones. (PubMed)

Serum concentrations of symmetric dimethylarginine and creatinine in cats with kidney stones. Serum concentrations of symmetric dimethylarginine (SDMA) correlate with renal function in cats and SDMA has been shown to be a more reliable and earlier marker for chronic kidney disease (CKD) compared with serum creatinine (Cr). Calcium oxalate uroliths tend to develop in mid-to-older aged cats and kidney stones may cause a reduction in renal function with increased SDMA, but normal serum Cr (...) . The purpose of this retrospective study was to determine if cats with kidney stones had increased serum SDMA concentrations, and whether SDMA increased earlier than serum creatinine concentrations. Cats in the colony with kidney stones diagnosed between August 2010 and December 2015 (n = 43) were compared with healthy geriatric cats (n = 21) without kidney stones. Serum SDMA concentrations were determined by liquid chromatography-mass spectrometry and serum Cr concentrations were determined by enzymatic

Full Text available with Trip Pro

2017 PLoS ONE

19. Assessment of elevated creatinine

Assessment of elevated creatinine Assessment of elevated creatinine - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of elevated creatinine Last reviewed: February 2019 Last updated: November 2018 Summary Serum creatinine concentration is maintained by the balance between its generation and excretion by the kidneys. Levels are affected by factors that influence the generation, glomerular filtration (...) , and tubular secretion of serum creatinine. There is considerable variation in the excretion of creatinine based on individual patient factors and the time and method of testing. Since creatinine is generated in a steady manner and can be measured very simply from blood samples, it has become a useful test to estimate glomerular filtration rate (GFR), which is a measurement of kidney function. The reference range of serum creatinine is: 60 to 110 micromol/L (0.7 to 1.2 mg/dL) for men 45 to 90 micromol/L

2018 BMJ Best Practice

20. Assessment of elevated creatinine

Assessment of elevated creatinine Assessment of elevated creatinine - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of elevated creatinine Last reviewed: February 2019 Last updated: November 2018 Summary Serum creatinine concentration is maintained by the balance between its generation and excretion by the kidneys. Levels are affected by factors that influence the generation, glomerular filtration (...) , and tubular secretion of serum creatinine. There is considerable variation in the excretion of creatinine based on individual patient factors and the time and method of testing. Since creatinine is generated in a steady manner and can be measured very simply from blood samples, it has become a useful test to estimate glomerular filtration rate (GFR), which is a measurement of kidney function. The reference range of serum creatinine is: 60 to 110 micromol/L (0.7 to 1.2 mg/dL) for men 45 to 90 micromol/L

2018 BMJ Best Practice

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>