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Serum Aldolase

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1. Serum Aldolase

Serum Aldolase Serum Aldolase Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Serum Aldolase Serum Aldolase Aka: Serum Aldolase II (...) . Interpretation: Normal Aldolase < 6 U/L III. Interpretation: Increased Aldolase or Trichinosis and other liver disease Hemorrhagic Gangrene IV. Interpretation: Decreased Aldolase Loss of muscle mass Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Serum Aldolase." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Aldolase measurement (C0201839) Definition

2018 FP Notebook

2. Serum Aldolase

Serum Aldolase Serum Aldolase Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Serum Aldolase Serum Aldolase Aka: Serum Aldolase II (...) . Interpretation: Normal Aldolase < 6 U/L III. Interpretation: Increased Aldolase or Trichinosis and other liver disease Hemorrhagic Gangrene IV. Interpretation: Decreased Aldolase Loss of muscle mass Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Serum Aldolase." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Aldolase measurement (C0201839) Definition

2015 FP Notebook

3. Serum aldolase and phosphocreatine kinase in umbilical cord blood (PubMed)

Serum aldolase and phosphocreatine kinase in umbilical cord blood Aldolase was estimated in the cord blood of 81 newborn infants and phosphocreatine kinase in 87 infants. There is a wide range in the results, with some values falling in the range reported in children with muscular dystrophy or of carriers of the disease. There is no correlation of the serum enzyme levels with the infant's birth weight. High levels of phosphocreatine kinase were found in infants of mothers with pre-eclamptic (...) toxaemia. A single estimation of cord phosphocreatine kinase and aldolase is of little help in determining whether or not an infant has muscular dystrophy.

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1966 Journal of Clinical Pathology

4. Aldolase Activity in the Plasma or Serum of Normal Children and Families with Muscular Dystrophy (PubMed)

Aldolase Activity in the Plasma or Serum of Normal Children and Families with Muscular Dystrophy 14021638 1998 11 01 2018 12 01 0003-9888 38 1963 Jun Archives of disease in childhood Arch. Dis. Child. Aldolase activity in the plasma or serum of normal children and families with muscular dystrophy. 208-14 CLAYTON B E BE WILSON K M KM CARTER C O CO eng Journal Article England Arch Dis Child 0372434 0003-9888 EC 4.1.2.13 Fructose-Bisphosphate Aldolase OM Child Fructose-Bisphosphate Aldolase Humans (...) Muscular Dystrophies ALDOLASE MUSCULAR DYSTROPHY 1963 6 1 1963 6 1 0 1 1963 6 1 0 0 ppublish 14021638 PMC2019036 Ann Hum Genet. 1961 May;25:41-9 13761775 Am J Phys Med. 1955 Feb;34(1):313-9 14361709 Dtsch Z Nervenheilkd. 1955;173(5-6):482-98 13305346 Proc Staff Meet Mayo Clin. 1954 Nov 10;29(23):591-603 13215569 Ann Hum Genet. 1959 Apr;23(2):127-63 13637556 Brain. 1957 Dec;80(4):557-70 13499760 J Lab Clin Med. 1958 May;51(5):745-52 13539491 Am J Hum Genet. 1960 Mar;12:52-66 13810211 J Pediatr. 1959 Jan

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1963 Archives of Disease in Childhood

5. Polymyositis with elevated serum IgG4 levels and abundant IgG4+ plasma cell infiltration: A case report and literature review. (PubMed)

differential diagnosis. Herein, we report the first case of PM with elevated serum IgG4 levels and IgG4 plasma cells in the muscles, mimicking IgG4-RD.A 73-year-old woman visited our hospital because of proximal muscle weakness of both thighs. Her blood test showed high levels of serum creatinine kinase, aldolase, and IgG4. Magnetic resonance imaging of the thighs showed muscle edema. Needle electromyography showed findings typical of myositis. Histological analysis of her left quadriceps revealed (...) Polymyositis with elevated serum IgG4 levels and abundant IgG4+ plasma cell infiltration: A case report and literature review. Polymyositis (PM) is a type of autoimmune, inflammatory myopathy. IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by elevated serum IgG4 levels and IgG4 plasma-cell infiltration of various organs. However, several reports have described cases of other diseases that present with those features, suggesting the importance of careful

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2017 Medicine

6. Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis (PubMed)

confirmed or ruled out for TB by culture and clinical follow-up. HIV coinfection was present in 34% of samples, and 25% were sputum smear negative. Serum protein biomarkers were identified by stability selection using L1-regularized logistic regression and by Kolmogorov-Smirnov (KS) statistics. A naive Bayes classifier using six host response markers (HR6 model), including SYWC, kallistatin, complement C9, gelsolin, testican-2, and aldolase C, performed well in a training set (area under the sensitivity (...) Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis New non-sputum biomarker tests for active tuberculosis (TB) diagnostics are of the highest priority for global TB control. We performed in-depth proteomic analysis using the 4,000-plex SOMAscan assay on 1,470 serum samples from seven countries where TB is endemic. All samples were from patients with symptoms and signs suggestive of active pulmonary TB that were systematically

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2017 Journal of clinical microbiology

7. Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy (PubMed)

Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy The comparative proteomic data presented in this article provide supporting information to the related research article "Proteomic identification of elevated saliva kallikrein levels in the mdx-4cv mouse model of Duchenne muscular dystrophy " (Murphy et al., 2018). Here we provide additional datasets on the comparative proteomic analysis of saliva (...) and serum proteins and the mass spectrometric identification of kallikrein isoform Klk-1 in wild type versus mdx-4cv saliva specimens. The data article presents the systematic identification of the assessable saliva proteome and the differential presence of proteins in saliva versus serum samples. Representative mass spectrometric scans of unique peptides that were employed to identify the kallikrein isoform Klk-1 in wild type versus mdx-4cv saliva specimens are provided. The dataset contains typical

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2018 Data in brief

8. Up-regulation of Aldolase B and Overproduction of Methylglyoxal in Vascular Tissues from Rats with Metabolic Syndrome. (PubMed)

, i.e. chronically fructose-fed hypertensive Sprague-Dawley rats, spontaneously hypertensive rats, obese non-diabetic Zucker rats, and diabetic Zucker rats, serum and aortic MG and fructose levels were increased, and the expression of GLUT5 (transporting fructose) and aldolase B (converting fructose to MG) in aorta were up-regulated. Aortic expressions of aldolase A, semicarbazide-sensitive amine oxidase (SSAO), and cytochrome P450 2E1 (CYP 2E1), accounting for MG formation during glycolysis (...) Up-regulation of Aldolase B and Overproduction of Methylglyoxal in Vascular Tissues from Rats with Metabolic Syndrome. Methylglyoxal (MG) overproduction has been reported in metabolic syndrome with hyperglycaemia (diabetes) or without hyperglycaemia (hypertension), and the underlying mechanism was investigated.Contributions of different pathways or enzymes to MG formation were evaluated in aorta or cultured vascular smooth muscle cells (VSMCs). In all four animal models of metabolic syndrome

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2011 Cardiovascular Research

9. Specific changes in the messenger ribonucleic acid content of the rat ventral prostate gland after androgenic stimulation. Evidence from the synthesis of aldolase messenger ribonucleic acid (PubMed)

a maximum after 8h of androgenic treatment and then declined. 4. The androgenic control of aldolase mRNA synthesis was also investigated in vivo. After treatment of castrated animals with various steroids in vivo [(35)S]methionine was injected directly into the prostate gland, and labelled aldolase was selectively precipitated from isolated polyribosomes with anti-aldolase serum. The regulation of aldolase mRNA synthesis in the prostate gland was stringently steroid-specific and could only be evoked (...) Specific changes in the messenger ribonucleic acid content of the rat ventral prostate gland after androgenic stimulation. Evidence from the synthesis of aldolase messenger ribonucleic acid 1. Aldolase was selected as a suitable marker for following the androgenic regulation of mRNA synthesis in the prostate gland. 2. Antibodies raised in rabbits against crystalline prostate aldolase were used to monitor the synthesis of this androgen-induced enzyme after hormonal stimulation of castrated

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1974 Biochemical Journal

10. Anti-retinal Antibodies in Serum of Laser-Treated Rabbits. (PubMed)

Anti-retinal Antibodies in Serum of Laser-Treated Rabbits. Retinal injuries that affect the photoreceptors and/or the retinal pigment epithelium (RPE) may result in the leakage of retinal proteins into the systemic circulation. This study was designed to determine whether an immune response is elicited after an acute retinal injury resulting in circulating anti-retinal antibodies in the serum.Fifty laser burns of different grades (minimally visible lesion [MVL], grade II [GII], or grade III (...) [GIII] lesions) were created in the retinas of Dutch Belted rabbits. The degree of laser burns was confirmed by fundus imaging and histology. Serum samples were collected from the animals 3 months after the retinal injury. Candidate autoantigens were identified by two-dimensional (2-D) Western blots of rabbit retinal lysate probed with sera from either control or laser-treated animals. Candidate autoantigens were further characterized by immunostaining to confirm their retinal localization.Seven

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2012 Investigative Ophthalmology & Visual Science

11. SERUM ENZYMES—Variations of Activity in Disease of Muscle (PubMed)

SERUM ENZYMES—Variations of Activity in Disease of Muscle In a study of 58 patients with various diseases of muscle or of the neuromuscular system, the serum activity of various enzymes was measured. Abnormal elevation of serum activities of aldolase, lactic dehydrogenase and, to a lesser extent, glutamic-oxalacetic transaminase and phosphohexose isomerase, was an almost constant feature in patients with progressive muscular dystrophy. These elevations were very frequent in dermatomyositis (...) in activity of lactic dehydrogenase and aldolase below that of control muscle and an increase of iso-citric dehydrogenase activity. These findings, taken with the differences in serum activities of lactic dehydrogenase, aldolase and isocitric dehydrogenase in the dystrophic animals, support the conclusion that dystrophic animals handle these soluble enzymes in quite different ways.

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1959 California Medicine

12. Serum Enzymes in Carriers of Muscular Dystrophy (PubMed)

Serum Enzymes in Carriers of Muscular Dystrophy 14449788 1998 11 01 2018 12 01 0007-1447 2 5310 1962 Oct 13 British medical journal Br Med J Serum enzymes in carriers of muscular dystrophy. 963-4 HUGHES B P BP eng Journal Article England Br Med J 0372673 0007-1447 EC 2.7.- Phosphotransferases EC 4.1.2.13 Fructose-Bisphosphate Aldolase OM Fructose-Bisphosphate Aldolase blood Heterozygote Humans Muscular Dystrophies blood Phosphotransferases blood ALDOLASE/blood MUSCULAR DYSTROPHY/blood

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1962 British medical journal

13. Serum Enzymes in Clinical Practice (PubMed)

Serum Enzymes in Clinical Practice 13955533 1998 11 01 2018 12 01 0035-9157 56 1963 Mar Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Serum enzyme changes in muscle disease and their relation to tissue change. 179-82 HUGHES B P BP eng Journal Article England Proc R Soc Med 7505890 0035-9157 EC 2.7.3.2 Creatine Kinase EC 4.1.2.13 Fructose-Bisphosphate Aldolase OM Clinical Enzyme Tests Creatine Kinase Fructose-Bisphosphate Aldolase Humans Muscular Diseases Muscular Dystrophies (...) ALDOLASE CREATINE KINASE ENZYME TESTS MUSCULAR DISEASES MUSCULAR DYSTROPHY 1963 3 1 1963 3 1 0 1 1963 3 1 0 0 ppublish 13955533 PMC1897332 Clin Chim Acta. 1962 Sep;7:597-603 13955534 J Neurol Neurosurg Psychiatry. 1962 Aug;25:191-202 14037852 AMA Arch Intern Med. 1959 Apr;103(4):551-64 13636473 J Biol Chem. 1959 Dec;234:3201-4 13836864 Brain. 1957 Dec;80(4):557-70 13499760 J Lab Clin Med. 1958 May;51(5):745-52 13539491 Br Med J. 1960 Oct 29;2(5208):1276-81 13776665 Rev Fr Etud Clin Biol. 1960 Apr;5:384

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1963 Proceedings of the Royal Society of Medicine

14. Biochemical Changes in Serum of Pure and Mixed Streptococcus faecalis and Bacillus subtilis Infections in Rats (PubMed)

Biochemical Changes in Serum of Pure and Mixed Streptococcus faecalis and Bacillus subtilis Infections in Rats Rats inoculated with Streptococcus faecalis developed endocarditis and demonstrated a 6- to 30-fold increase in aldolase, isocitric dehydrogenase, phosphohexose isomerase, and lactic dehydrogenase. The animals infected with Bacillus subtilis did not develop overt disease nor significant increases in enzyme activities, but viable organisms were recovered at 2 weeks. Rats inoculated (...) hr of infection of B. subtilis and S. faecalis mixed infections. The results indicate that B. subtilis infection modified the pathogenicity of S. faecalis and by an unknown mechanism affected protein and glycoprotein production in serum of experimental rats.

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1969 Applied microbiology

15. Influence of Bacterial Infection on Serum Enzymes of White Rats (PubMed)

Influence of Bacterial Infection on Serum Enzymes of White Rats Infection of white rats with Francisella tularensis (Pasteurella tularensis) and Salmonella typhimurium and exposure to the endotoxin of S. typhimurium stimulated significant increases in various serum enzymes including aldolase, lactate dehydrogenase, phosphohexose isomerase, isocitrate dehydrogenase, and glutamate-oxalacetate transaminase. The rates of changes in enzymatic activity after infection were directly related (...) to the size of infecting dose and to the type of infective agent employed. Tularemic infection stimulated excessive changes in enzyme activity, whereas salmonellosis and endointoxication elicited less pronounced alterations of relatively short duration. Changes observed in serum enzymes after exposure to these agents reflect the severe liver damage and extensive systemic involvement noted in tularemia as opposed to more localized and less intensive tissue damage occurring during salmonellosis

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1969 Applied microbiology

16. Serum enzyme changes after intramuscular bleeding in patients with haemophilia and Christmas disease (PubMed)

Serum enzyme changes after intramuscular bleeding in patients with haemophilia and Christmas disease Serum creatine kinase, lactate dehydrogenase, aspartate and alanine transaminases, and aldolase were determined in 41 hospital inpatients with haemophilia or Christmas disease and no significant differences from the normal ranges were found.(3) Levels of these enzymes in a further 10 such patients who had sustained muscle haematomata were determined: in all of these there was a consistent rise (...) in the level of creatine kinase, the peak occurring between 36 and 96 hours. In bleeding disorders a rise in serum creatine kinase levels may be useful as a diagnostic test for intramuscular haemorrhage.

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1972 Journal of Clinical Pathology

17. Serum enzymes in diseases of the thyroid gland (PubMed)

Serum enzymes in diseases of the thyroid gland Serum enzyme assays have been carried out in 66 patients suffering from diseases of the thyroid gland. Sixty per cent. of the hypothyroid patients had increased levels of aldolase and glutamic oxaloacetic transaminase, and 90% had high activities of creatine kinase. The significance of these findings, especially with regard to creatine kinase, is discussed.

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1965 Journal of Clinical Pathology

18. Estimation of Serum Enzymes (PubMed)

Estimation of Serum Enzymes 14331638 1996 12 01 2018 12 01 0007-1447 2 5462 1965 Sep 11 British medical journal Br Med J ESTIMATION OF SERUM ENZYMES. 648-9 GEORGE W H WH eng Journal Article England Br Med J 0372673 0007-1447 EC 1.- Oxidoreductases EC 1.1.1.27 L-Lactate Dehydrogenase EC 1.1.1.30 Hydroxybutyrate Dehydrogenase EC 1.1.1.41 Isocitrate Dehydrogenase EC 4.1.2.13 Fructose-Bisphosphate Aldolase OM Clinical Enzyme Tests Fructose-Bisphosphate Aldolase Hydroxybutyrate Dehydrogenase (...) Isocitrate Dehydrogenase L-Lactate Dehydrogenase Oxidoreductases ALDOLASE ENZYME TESTS HYDROXYBUTYRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE LACTATE DEHYDROGENASE OXIDOREDUCTASES 1965 9 11 1965 9 11 0 1 1965 9 11 0 0 ppublish 14331638 PMC1845985 Lancet. 1961 Apr 1;1(7179):698-9 13726426 Proc Soc Exp Biol Med. 1955 Oct;90(1):210-3 13273400

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1965 British medical journal

19. ALTERATIONS IN SERUM ENZYMES AFTER REPEATED EXPOSURE TO MALATHION (PubMed)

ALTERATIONS IN SERUM ENZYMES AFTER REPEATED EXPOSURE TO MALATHION 14261708 1996 12 01 2018 12 01 0007-1072 22 1965 Jan British journal of industrial medicine Br J Ind Med ALTERATIONS IN SERUM ENZYMES AFTER REPEATED EXPOSURE TO MALATHION. 67-71 GRECH J L JL eng Journal Article England Br J Ind Med 0370637 0007-1072 0 Insecticides 0 Serum Albumin EC 2.6.1.- Transaminases EC 3.1.1.8 Cholinesterases EC 4.1.2.13 Fructose-Bisphosphate Aldolase U5N7SU872W Malathion OM Agricultural Workers' Diseases (...) Blood Cholinesterases Clinical Enzyme Tests Fructose-Bisphosphate Aldolase Insecticides Malathion Poisoning Serum Albumin Toxicology Transaminases AGRICULTURAL WORKERS' DISEASES ALDOLASE AMINOTRANSFERASES BLOOD CHOLINESTERASE ENZYME TESTS INSECTICIDES POISONING SERUM ALBUMIN TOXICOLOGIC REPORT 1965 1 1 1965 1 1 0 1 1965 1 1 0 0 ppublish 14261708 PMC1008217 Experientia. 1952 Apr 15;8(4):146-8 14945443 Am J Clin Pathol. 1952 Nov;22(11):1126-33 12996458 Biochem Z. 1954;325(2):156-62 13159982 Proc Staff

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1965 British Journal of Industrial Medicine

20. Serum Enzyme Activity During Radiotherapy of Malignant Tumours (PubMed)

Serum Enzyme Activity During Radiotherapy of Malignant Tumours 14284374 1996 12 01 2018 12 01 0007-0920 19 1965 Mar British journal of cancer Br. J. Cancer SERUM ENZYME ACTIVITY DURING RADIOTHERAPY OF MALIGNANT TUMOURS. 134-8 HOLSTI L R LR eng Journal Article England Br J Cancer 0370635 0007-0920 EC 1.1.1.27 L-Lactate Dehydrogenase EC 2.6.1.1 Aspartate Aminotransferases EC 3.4.11.1 Leucyl Aminopeptidase EC 4.1.2.13 Fructose-Bisphosphate Aldolase OM Aspartate Aminotransferases Clinical Enzyme (...) Tests Esophageal Neoplasms Fructose-Bisphosphate Aldolase Humans L-Lactate Dehydrogenase Leucyl Aminopeptidase Lung Neoplasms Mediastinal Neoplasms Neoplasms radiotherapy Radiotherapy, High-Energy Stomach Neoplasms Urinary Bladder Neoplasms ALDOLASE ASPARTATE AMINOTRANSFERASE BLADDER NEOPLASMS ENZYME TESTS ESOPHAGEAL NEOPLASMS LACTATE DEHYDROGENASE LEUCINE AMINOPEPTIDASE LUNG NEOPLASMS MEDIASTINAL NEOPLASMS NEOPLASM RADIOTHERAPY RADIOTHERAPY, HIGH ENERGY STOMACH NEOPLASMS 1965 3 1 1965 3 1 0 1 1965

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1965 British journal of cancer

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