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Semen Analysis

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1. Racial and Sociodemographic Differences of Semen Parameters among US Men Undergoing a Semen Analysis. (PubMed)

Racial and Sociodemographic Differences of Semen Parameters among US Men Undergoing a Semen Analysis. To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis.Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal parameters were compared and risks (...) of oligospermia and azoospermia were assessed by logistic regression.Of the 7263 men included, most men were white (55.1%), Hispanic (20.2%), or Asian (10.2%). Asians had the highest mean semen concentrations (69.2 × 106/mL), whereas blacks had the lowest (51.3 × 106/mL). Men from the Midwest were more likely to have oligospermia (odds ratio [OR] 1.62; 95% confidence interval [CI] 1.34-1.94), whereas men from the West were less likely (OR 0.82; 95% CI 0.82-0.94) when compared with men from South

2018 Urology

2. the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis

the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov

2017 Clinical Trials

3. The association between vitamin D and semen quality: a systematic review and meta-analysis of observational studies

The association between vitamin D and semen quality: a systematic review and meta-analysis of observational studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated (...) . ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach If a meta-analysis

2019 PROSPERO

4. Association between outdoor air pollution and semen quality, an updated meta-analysis and systematic review

Association between outdoor air pollution and semen quality, an updated meta-analysis and systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) . ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach If a meta-analysis

2019 PROSPERO

5. Benefits of Empiric Nutritional and Medical Therapy for Semen Parameters and Pregnancy and Live Birth Rates in Couples with Idiopathic Infertility: A Systematic Review and Meta-analysis. (PubMed)

Benefits of Empiric Nutritional and Medical Therapy for Semen Parameters and Pregnancy and Live Birth Rates in Couples with Idiopathic Infertility: A Systematic Review and Meta-analysis. Empiric use of medical and nutritional supplements to improve semen parameters and pregnancy rates in couples with idiopathic infertility has reached global proportions, although the evidence base for their use in this setting is controversial.We systematically reviewed evidence comparing the benefits (...) of nutritional and medical therapy on pregnancy rates and semen parameters in men with idiopathic infertility.A literature search was performed using MEDLINE, Embase, LILACS, and the Cochrane Library (searched from January 1, 1990 to September 19, 2017). using the methods detailed in the Cochrane Handbook. Grading of Recommendations Assessment, Development and Evaluation (GRADE) was used to assess the certainty of evidence.The literature search identified 5663 citations, and after screening of abstracts

2019 European Urology

6. Tobacco smoking and semen quality in infertile males: a systematic review and meta-analysis. (PubMed)

Tobacco smoking and semen quality in infertile males: a systematic review and meta-analysis. Nowadays, the total number of couples visiting an infertility clinic is on the rise. Tobacco smoking is considered one of the major factors leading to male infertility. In this study, we aimed to systematically investigate the impact of tobacco smoking on semen quality in infertile male participants.Online databases (Cochrane Central database of Randomized Controlled Trials and the databases of MEDLINE (...) and EMBASE respectively) were searched for relevant English publications that satisfied the inclusion and exclusion criteria of this analysis. The clinical endpoints which were assessed included semen parameters (oligozoospermia, asthenozoospermia, teratozoospermia, and azoospermia), morphological defects of spermatozoa and the hormones involved in reproduction. RevMan 5.3 software was used to analyze the data whereby mean difference (MD) and risk ratios (RR) with 95% confidence intervals (CI) were

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2019 BMC Public Health

7. Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. (PubMed)

Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. What is the prevalence and the relationship of anti-sperm antibodies (ASA), screened by means of IgG-mixed anti-globulin reaction (MAR) test, to semen quality and post-coital test (PCT) outcome?A 100% positive IgG-MAR test, detected in 2% of the study population, was associated with lower sperm output (...) and progressive motility, and was the sole determinant of higher prevalence of a negative PCT outcome.Although ASA may affect sperm fertilizing ability and the IgG-MAR test is recommended by the World Health Organization (WHO) as an integral part of semen analysis for screening the occurrence of ASA, the prevalence and clinical relevance of positive MAR test results remain controversial.A retrospective analysis of 12 296 consecutive men who attended a university/hospital andrology clinic for the evaluation

2019 Human Reproduction

8. Association between outdoor air pollution and semen quality: Protocol for an updated systematic review and meta-analysis. (PubMed)

Association between outdoor air pollution and semen quality: Protocol for an updated systematic review and meta-analysis. Various studies have explored the association between outdoor air pollution and semen quality. However, the results were still controversial. The object of the current meta-analysis is to evaluate the role of outdoor air pollution in semen quality.Databases including PubMed, Web of Science, and Embase will be searched to identify qualified studies. All qualified cross (...) will be the primary outcomes of the current study. Pooled estimates with corresponding 95% confidence intervals will be calculated to assess the specific effects of outdoor air pollution in semen quality. Moreover, trial sequential analyses will be performed to obtain a more comprehensive assessment of analyses.A high-quality synthesis of the current evidence for the association between sperm parameters and outdoor air pollution will be provided.This meta-analysis and systematic review will generate evidence

2019 Medicine

9. Proteomic analysis reveals the negative modulator of sperm function glycodelin as over-represented in semen exosomes isolated from asthenozoospermic patients. (PubMed)

Proteomic analysis reveals the negative modulator of sperm function glycodelin as over-represented in semen exosomes isolated from asthenozoospermic patients. Are there differences in the proteomic profile of exosomes isolated from seminal plasma of normozoospermic (NSP) and severe asthenozoospermic (SA) men, potentially contributing to sperm features?A relevant group of proteins known to positively regulate sperm functions were over-represented in seminal exosomes of NSP men, i.e. cysteine (...) at a single IVF center, were considered for this study project. Subjects were subdivided into three groups: a discovery cohort (five NSP men and six SA patients), a validation cohort (seven NSP and seven SA men) and the 'glycodelin analysis' cohort (20 NSP and 37 SA men). Exosomes were purified from semen of every participant.Exosomes were characterized by nanoparticle tracking analysis, transmission electron microscopy and western blot. Comprehensive proteomics analysis of the exosomal proteome

2019 Human Reproduction

10. Is low body mass index a risk factor for semen quality? A PRISMA-compliant meta-analysis. (PubMed)

Is low body mass index a risk factor for semen quality? A PRISMA-compliant meta-analysis. Male infertility has become a worldwide public health problem. However, the effect of low body mass index (BMI) is still controversial.Relevant articles in Pubmed, Embase, Web of science, and Wanfang database published until September 2017 were searched without language restriction. We performed a meta-analysis about low BMI and semen parameters containing total sperm count, concentration, semen volume (...) , and sperm motility (overall and progressive), including 709 men with low BMI and 14,622 men with normal BMI.Thirteen studies were included in this meta-analysis and a total of 15,331 individuals were accumulated. We pooled data from these articles and found standardized weighted mean differences in semen parameters (total sperm count and semen volume) showed significant difference between low BMI and normal BMI.This systematic review with meta-analysis has confirmed that there was a relationship between

2019 Medicine

11. Effects of physical exercises on semen quality and reproductive outcomes in male infertility: A protocol for systematic review and meta-analysis of randomized controlled trials. (PubMed)

Effects of physical exercises on semen quality and reproductive outcomes in male infertility: A protocol for systematic review and meta-analysis of randomized controlled trials. Infertility has troubled the world's 186 million people, and male infertility accounts for more than half. The literature of physical exercise related to semen quality has shown inconsistent results, and there is currently no systematic review to evaluate the effects of exercise on reproductive outcomes in male (...) . Systematic review and meta-analysis will be produced by RevMan 5.3 and Stata 14.0. This protocol reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) statement, and we will report the systematic review by following the PRISMA statement.We will assess the efficacy and safety of physical exercise on semen quality and reproductive outcomes in infertile men. The findings will be published in a peer-reviewed journal to provide evidence-based

2019 Medicine

12. Cigarette Smoking and Semen Quality: A New Meta-analysis Examining the Effect of the 2010 World Health Organization Laboratory Methods for the Examination of Human Semen. (PubMed)

Cigarette Smoking and Semen Quality: A New Meta-analysis Examining the Effect of the 2010 World Health Organization Laboratory Methods for the Examination of Human Semen. Approximately 37% of men of reproductive age smoke cigarettes, with Europe having the highest tobacco use among all the World Health Organization (WHO) regions. Toxins from tobacco smoking can potentially affect sperm development and function, with a negative effect on semen parameters. Given the high prevalence of smoking (...) and recent changes in the WHO laboratory methods for the examination of human semen, the role of this exposure in face of new WHO methods needs to be clarified.We conducted a systematic review, followed by a meta-analysis, to determine whether cigarette smoking affects human semen parameters. PubMed, Saint Joseph's University Discover, and Google Scholar were used to identify relevant studies published after release of the latest WHO methods for laboratory evaluation of human semen. Participants were

2016 European Urology

13. Re: Reecha Sharma, Avi Harlev, Ashok Agarwal, Sandro C. Esteves. Cigarette Smoking and Semen Quality: A New Meta-analysis Examining the Effect of the 2010 World Health Organization Laboratory Methods for the Examination of Human Semen. Eur Urol. In press. (PubMed)

Re: Reecha Sharma, Avi Harlev, Ashok Agarwal, Sandro C. Esteves. Cigarette Smoking and Semen Quality: A New Meta-analysis Examining the Effect of the 2010 World Health Organization Laboratory Methods for the Examination of Human Semen. Eur Urol. In press. 27317089 2018 04 05 2018 12 02 1873-7560 71 1 2017 01 European urology Eur. Urol. Re: Reecha Sharma, Avi Harlev, Ashok Agarwal, Sandro C. Esteves. Cigarette Smoking and Semen Quality: A New Meta-analysis Examining the Effect of the 2010 World (...) A Division of ExperimentalOncology/Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy; Università Vita-Salute San Raffaele, Milan, Italy. Electronic address: salonia.andrea@hsr.it. eng Letter Comment 2016 06 15 Switzerland Eur Urol 7512719 0302-2838 IM Eur Urol. 2016 Oct;70(4):635-645 27113031 Eur Urol. 2017 Jan;71(1):e21-e22 27289568 Cigarette Smoking Humans Male Semen Semen Analysis Smoking World Health Organization 2016 05 04 2016 05 31 2016 6 19 6 0 2018 4 6 6 0 2016 6 19 6 0 ppublish

2016 European Urology

14. Assessment of motion and kinematic characteristics of frozen-thawed Sirohi goat semen using computer-assisted semen analysis (PubMed)

Assessment of motion and kinematic characteristics of frozen-thawed Sirohi goat semen using computer-assisted semen analysis The aim was to determine the motion and kinematics characteristic of frozen-thawed spermatozoa in Sirohi goat using computer-assisted semen analysis.A study was carried out in Sirohi buck. Semen collection was made biweekly from each buck with the help of artificial vagina. A total of 12 ejaculates were collected from two bucks (six ejaculates from each buck). Freshly (...) collected semen was pooled and later evaluated. The pooled semen sample was extended with standard glycerolated egg yolk tris extender and later subjected to a process of cryopreservation. The motion and kinematic characteristics of spermatozoa were studied during freez-thawing process.Significantly (p<0.01) higher value of live percent, hypo-osmotic swelling test, and acrosomal integrity were recorded in neat semen followed by diluted and frozen thaw semen. The proportion of spermatozoa showing slow

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2016 Veterinary world

15. Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials

Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized clinical trials Impact of surgical varicocele repair on pregnancy rate in subfertile men with clinical varicocele and impaired semen quality: a meta-analysis of randomized (...) for inclusion. The participants in the included trials had a clinical or subclinical varicocele that was or was not palpable, abnormal semen analysis, or both. Control participants received no treatment, delayed surgery or clomiphene citrate. Surgical approaches varied across trials. Two reviewers applied the inclusion criteria, with disagreements resolved by discussion or by arbitration. Assessment of study quality Trial quality was assessed using the Cochrane risk of bias tool, which evaluates

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2013 DARE.

16. Inconsistent Adoption of World Health Organization V (2010) Semen Analysis Reference Ranges in the United States Six Years After Publication. (PubMed)

Inconsistent Adoption of World Health Organization V (2010) Semen Analysis Reference Ranges in the United States Six Years After Publication. To determine the percentage of laboratories in the United States that have adopted the World Health Organization 2010 (WHO 5) semen analysis (SA) reference values 6 years after their publication.Laboratories were identified via 3 approaches: using the Clinical Laboratory Improvement Amendments (CLIA) website, the CDC's 2015 Assisted Reproductive (...) Technology Fertility Clinical Success Rate Report, and automated web searches. Laboratories were contacted by phone or email to obtain de-identified SA reports and reference ranges.We contacted 617 laboratories in 46 states, of which 208 (26.7%) laboratories in 45 states were included in our analysis. 132 (63.5%) laboratories used WHO 5 criteria, 57 (27.4%) used WHO 4 criteria, and 19 (9.1%) used other criteria. WHO 5 criteria adoption rates varied by geographic region, ranging from 87.5% (35/40

2018 Urology

17. Testicular histopathology, semen analysis and FSH, predictive value of sperm retrieval: supportive counseling in case of reoperation after testicular sperm extraction (TESE). (PubMed)

Testicular histopathology, semen analysis and FSH, predictive value of sperm retrieval: supportive counseling in case of reoperation after testicular sperm extraction (TESE). To provide indicators for the likelihood of sperm retrieval in patients undergoing testicular sperm extraction is a major issue in the management of male infertility by TESE. The aim of our study was to determine the impact of different parameters, including testicular histopathology, on sperm retrieval in case (...) of reoperation in patients undergoing testicular sperm extraction.We retrospectively analyzed 486 patients who underwent sperm extraction for intracytoplasmic sperm injection and testicular biopsy. Histology was classified into: normal spermatogenesis; hypospermatogenesis (reduction in the number of normal spermatogenetic cells); maturation arrest (absence of the later stages of spermatogenesis); and Sertoli cell only (absence of germ cells). Semen analysis and serum FSH, LH and testosterone were

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2018 BMC Urology

18. Do pregnancy rates differ with intra-uterine insemination when different combinations of semen analysis parameters are abnormal? (PubMed)

Do pregnancy rates differ with intra-uterine insemination when different combinations of semen analysis parameters are abnormal? To evaluate the relationship of one or a combination of semen analysis parameter results on insemination outcomes.A retrospective analysis was performed to evaluate the effect on pregnancy rates in relation to one or more abnormal semen analysis parameters based on the 2010 World Health Organization semen analysis guidelines.Nine hundred eighty-one couples underwent (...) 2231 intrauterine insemination cycles at the Stanford Fertility and Reproductive Medicine Center. In our study, the pregnancy rates ranged from 11-25% when an individual or combined semen analysis parameters were analyzed. Similar pregnancy rates were found when one, two, and in most cases three parameters were abnormal. When a single parameter was abnormal among volume, concentration, and motility, pregnancy rates were mainly unaffected. There was the exception of total sperm count where pregnancy

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2018 Journal of the Turkish German Gynecological Association

19. Analysis on the association between sperm DNA fragmentation index and conventional semen parameters, blood microelements and seminal plasma ROS in male patients with infertility (PubMed)

Analysis on the association between sperm DNA fragmentation index and conventional semen parameters, blood microelements and seminal plasma ROS in male patients with infertility We conducted this study to analyze the sperm DNA fragmentation index, conventional semen parameters, blood microelements and seminal plasma reactive oxygen species (ROS) in patients with male infertility to determine the association between each of the above male physiological parameters and DNA fragmentation index (...) and infertility. Eighty cases of infertile males and 20 cases of normal males with children were divided into the infertility and control groups, respectively. Sperm DNA fragmentation index, conventional semen parameters, serum microelement content and seminal plasma ROS levels were detected, and the existing correlation between sperm DNA fragmentation index and the various physiological parameters were studied. The sperm DNA fragmentation index had no correlation with conventional sperm parameters. Our

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2018 Experimental and therapeutic medicine

20. Semen analysis in patients treated for varicocele in pediatric age: are surgical outcomes enough to preserve the fertility potential? (PubMed)

Semen analysis in patients treated for varicocele in pediatric age: are surgical outcomes enough to preserve the fertility potential? Preserving the fertility potential of adolescent patients with varicocele is still the main outcome of pediatric and adolescent urologysts; the aim of this study is to assess the fertility potential of patients treated for varicocele with testicular hypotrophy in absence of post-operative complications, with complete ipsilateral testicular catch-up growth (...) and normal hormonal values.The Authors collected data from adolescents with varicocele aged between 10 and 16 years treated at their Institution between September 2010 and September 2015. Inclusion and exclusion criteria were created; all patients were followed clinically and with hormonal tests before and after surgery and then re-evaluated after semen analysis. Semen quality was correlated with hormonal status, surgical complications and testicular volume.133 subjects without recurrences

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2018 American journal of clinical and experimental urology

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