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Self Skin Exam

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181. Gene Expression and Biomarker Profiling of Keloid Skin

: Regeneron Pharmaceuticals Information provided by (Responsible Party): Roopal Kundu, Northwestern University Study Details Study Description Go to Brief Summary: This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: Differences in the genetic profiles of lesional and non-lesional skin contribute a given population's propensity to develop keloids Differences in biomolecules expressed in subjects with and without keloids can help predict (...) . Procedure: Biopsy and/or triamcinolone injection Subjects will have their blood drawn during the first study visit. Subsequently, a punch biopsy and/or triamcinolone injection will be given based on group timeline. Active Comparator: Group 5 Normal patient skin (surgical or adjacent to other biopsy) from subjects with no self-reported history of keloids. Procedure: Biopsy and/or triamcinolone injection Subjects will have their blood drawn during the first study visit. Subsequently, a punch biopsy

2017 Clinical Trials

182. A Proof of Concept Clinical Study to Investigate the Effects of an Experimental Cosmetic Moisturiser on the Barrier Function of Human Skin on the Face and Forearm

history or upon physical examination. Self-reported dry, sensitive skin on the face and body. Agreement to comply with the procedures and requirements of the study and to attend the scheduled assessment visits. Trained examiner visual grading assessment score (including subject self-assessment of tightness) of overall dryness ≥ 3 with a score of at least 1 in the roughness parameter and 4 (for any individual parameter) on each of the forearms and each side of the face at the Screening visit (Visit 1 (...) ) and Baseline visit (Visit 2). In addition, there will be no greater than 0.5 point difference between trained examiner visual grading scores of each volar forearm and each side of the face at the Screening and Baseline visits. Fitzpatrick skin type I-IV Exclusion Criteria: Women who are known to be pregnant or who are intending to become pregnant over the duration of the study. Women who are breast-feeding. Any history of significant dermatological diseases or conditions or medical conditions known

2017 Clinical Trials

183. The Juice Study: Sensitivity of Skin Carotenoid Status to Detect Change in Intake

vegetable juice Other: Control bottled water Not Applicable Detailed Description: The US Dietary Guidelines for Americans recommends that individuals consume approximately 2-4 c of vegetables each day to reduce risk of chronic disease, but current methods for assessing intake are either inaccurate (self-report) or invasive (blood carotenoid levels). Recent research indicates that skin carotenoid status may be a useful biomarker of vegetable intake, but the sensitivity to dose in unknown. In this study (...) will be compared to blood carotenoid concentrations and single nucleotide polymorphisms (SNPs) of genes related to the uptake, transport, and metabolism of carotenoids will be examined in blood and saliva. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 80 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Other Official Title: Sensitivity of Skin Carotenoid Status

2017 Clinical Trials

184. Public primary and secondary skin cancer prevention, perceptions and knowledge: An international cross-sectional survey. Full Text available with Trip Pro

behaviours regarding sun exposure and skin cancer detection at an international scale.A questionnaire was submitted, both online and by telephone, to a representative sample (based on official demographic statistics on gender, age and region) of people aged from 15 to 65 originating from 23 countries. Questions dealt with demographics, sun exposure and protection, risk knowledge, self-examination, medical advice seeking. Data were then gathered and analysed at different levels.A total of 19 569 (...) respondents were recruited. Overall, sunscreen and sunglasses were the most used measures for sun protection. There were however difference between countries and geographical areas. Some high-risk countries in terms of sun exposure (according to their location to Equator) exhibited higher rates of primary preventative behaviours, in particular Australia, Chile and Greece. There were also discrepancies between countries regarding secondary prevention through self-examination and medical advice seeking

2017 Journal of the European Academy of Dermatology and Venereology

185. Impact of a video-based intervention to improve the prevalence of skin self-examination in men 50 years or older: the randomized skin awareness trial. Full Text available with Trip Pro

Impact of a video-based intervention to improve the prevalence of skin self-examination in men 50 years or older: the randomized skin awareness trial. To improve the proportion of men 50 years or older who conduct a thorough whole-body skin self-examination (SSE), because these men are at increased risk of being diagnosed as having thick melanomas and dying of melanoma.Randomized trial of a video-based intervention to increase whole-body SSE compared with brochures-only control.Men from (...) increased their whole-body SSE behaviors similarly (36% intervention and 31% control) (P = .85). At 7 months, the intervention group was significantly more likely to examine at least 1 part of their back (P < .001) and to examine a greater number of body sites (P < .001). At 7 months, the proportion of men conducting any SSE increased by 28% in the intervention group compared with 13% in the control group (P < .001), but at 13 months, the prevalence of any self-examination (83% vs 80%) was again

2011 Archives of Dermatology Controlled trial quality: uncertain

186. Self-management interventions to improve skin care for the prevention of pressure ulcers in people with a spinal cord injury

Self-management interventions to improve skin care for the prevention of pressure ulcers in people with a spinal cord injury Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) , a threshold describing the number of studies per subgroup required for analysis should be specified. For further guidance please refer to the and to pre-clinical meta-analysis. Example: The following study characteristics will be examined as potential source of heterogeneity: species (stratified per species); sex (stratified per sex); duration of index ischemia (linear); stem cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8

2016 PROSPERO

187. Use of 2-octyl cyanoacrylate together with a self-adhering mesh (Dermabondâ„¢ Prineoâ„¢) for skin closure following abdominoplasty: an open, prospective, controlled, randomized, clinical study. (Abstract)

Use of 2-octyl cyanoacrylate together with a self-adhering mesh (Dermabondâ„¢ Prineoâ„¢) for skin closure following abdominoplasty: an open, prospective, controlled, randomized, clinical study. Abdominoplasty is one of the most commonly performed procedures in plastic surgery. The appearance of the scar is a major factor that contributes to the aesthetic outcome of the procedure and depends largely on the technique of wound closure. The new Prineo™ wound closure system was introduced to combine (...) the effectiveness of 2-octyl cyanoacrylate (Dermabond™) together with a self-adhering mesh.Fifty-two women and eight men aged between 21 and 65 years who were scheduled for abdominoplasty were included in the study. The total operating times after abdominoplasty of the traditional wound closure technique and the Prineo™-type wound closure technique were compared. Furthermore, an analysis comparing the cost of the two methods was performed. Two weeks after surgery the wounds were examined and graded using

2013 Aesthetic plastic surgery Controlled trial quality: uncertain

188. Facilitating Skin-to-Skin Contact In the Postnatal Period

2016). This study examines the effect a facilitating garment, the Snuby® has on neonatal health outcomes associated with skin-to-skin contact, such as neonatal thermoregulation, breastfeeding status, and self-reported mother-infant bonding. It uses a mixed methods approach to address quantitative and qualitative outcomes including participant's perspectives, and measurable health markers. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated (...) : Six weeks post birth ] Maternal participants will self report on their perspectives of skin-to-skin contact, and its role in the relationship bonding process between themselves and their babies. Neonatal Weight Velocity [ Time Frame: At a minimum of 3 intervals, including at birth, ten days, and at six weeks post birth. ] Neonatal weight in grams to ensure suitable for Snuby® garment. Maternal participant's perspective [ Time Frame: Weekly until 6 weeks post birth ] Maternal participants will self

2016 Clinical Trials

189. Achieving Self-directed Integrated Cancer Aftercare (ASICA) in Melanoma

patients who have been treated for melanoma are advised to regularly examine their own skin (total-skin-self-examinations; TSSE) but research has found that many people are not shown how to do this effectively. We are investigating whether a digital app we have developed (ASICA) can help people with melanoma to use a hand-held tablet computer to do more regular and effective TSSE, and whether this would lead to earlier detection of recurrent and new primary melanomas. The ASICA app also uses (...) . Patients choose the answers on a 10-point scale ranging from 'not at all confident' (worst answer) to 'highly confident' (best answer). The final set of questions ask patients whether they have found anything concerning during their last skin check (yes/no answer) and if so what action was taken by the patient (watched it/showed it to a relative/showed it to a professional) and how quickly (immediately, in few days, in a week, in a month, other). The impact of receiving ASICA on adherence to and self

2017 Clinical Trials

190. Surgical Indications and Outcomes of Mastectomy in Transmen: A Prospective Study of Technical and Self-Reported Measures. Full Text available with Trip Pro

, concentric circular mastectomy was associated with more secondary corrections (38.5 percent), dehiscence, seroma, and lower postoperative satisfaction compared with inframammary skin resections. Clinical decision-making was generally in line with the published decision aid.Compared with inframammary skin resections, concentric circular mastectomy-despite being performed in favorable breast types-appears to produce poorer technical and self-reported outcomes. Surgical indications and preoperative (...) Surgical Indications and Outcomes of Mastectomy in Transmen: A Prospective Study of Technical and Self-Reported Measures. Although transgender surgery constitutes a growing field within plastic surgery, prospective studies on masculinizing mastectomies are lacking. The objectives of the present study were to prospectively follow a cohort of transmen undergoing mastectomy to assess technical and self-reported outcomes and to evaluate surgical decision-making.Fifty-four transmen were recruited

2017 Plastic and reconstructive surgery

191. Development and Validation of a Taxonomy for Characterizing Measurements in Health Self-Quantification. Full Text available with Trip Pro

Development and Validation of a Taxonomy for Characterizing Measurements in Health Self-Quantification. The use of wearable tools for health self-quantification (SQ) introduces new ways of thinking about one's body and about how to achieve desired health outcomes. Measurements from individuals, such as heart rate, respiratory volume, skin temperature, sleep, mood, blood pressure, food consumed, and quality of surrounding air can be acquired, quantified, and aggregated in a holistic way that has (...) to build evidence of sufficient quality to determine whether and how health SQ is a worthwhile health care paradigm.The aim of this study was to investigate a sample of SQ tools and services to build and test a taxonomy of measurements in health SQ, titled: the classification of data and activity in self-quantification systems (CDA-SQS).Eight health SQ tools and services were selected to be examined: Zeo Sleep Manager, Fitbit Ultra, Fitlinxx Actipressure, MoodPanda, iBGStar, Sensaris Senspod, 23andMe

2017 Journal of medical Internet research

192. Self-healing juvenile cutaneous mucinosis Full Text available with Trip Pro

Self-healing juvenile cutaneous mucinosis Girl, aged 4 years old, began the disease with pain of the lower extremities, fever up to 38°C and signs of upper airway infection. Then the patient developed oedema and redness of the whole face, thickened skin, subcutaneous nodular foldings of the frontal, occipital, cervical and axillary regions, extensor areas of the joints; fine, hard whitish nodules in the frontal region and over interphalangeal joints of the hands, pruritus; oedemas of the ankles (...) , knees and joints of the hands, cervical lymphadenopathy and hepatomegaly. Blood tests at the moment of the diagnosis revealed elevation of markers of inflammation as ESR and CRP, leukocytosis, thrombocytosis, hypoalbuminemia, and hyper-alfa-2-globulinemia. Histopathological examination of the skin biopsy specimen and subcutaneous tissue revealed myxoid subcutaneous tissue located under the dermis and a section consisting of myxoid mesenchymal tissue with inflammatory infiltration by histiocytic

2017 Reumatologia

193. Rhesus macaques (Macaca mulatta) displaying self-injurious behavior show more sleep disruption than controls Full Text available with Trip Pro

Rhesus macaques (Macaca mulatta) displaying self-injurious behavior show more sleep disruption than controls Self-injurious behavior (SIB) is a pathology observed in both humans and animals. In humans, SIB has been linked to various mental health conditions that are also associated with significant sleep disruption. In rhesus macaques, SIB consists of self-directed biting which can range from mild skin abrasions to wounds requiring veterinary care. However, only one study suggests possible (...) sleep disruption in macaques with SIB. We evaluated sleep disruption using a noninvasive system (infra-red camera and a video surveillance program) which created videos for every movement over the nighttime hours. Nighttime activity was examined in 13 macaques (three females) of which six were classified as having SIB (one female). Each monkey was studied for a total of 6 nights spanning a period of 4 months. Measures included total movement time (TMT), time moving in the first hour (HR1), time

2017 Applied Animal Behaviour Science

194. Self-reported versus health administrative data: implications for assessing chronic illness burden in populations. A cross-sectional study Full Text available with Trip Pro

Self-reported versus health administrative data: implications for assessing chronic illness burden in populations. A cross-sectional study Various data sources may be used to document the presence of chronic medical conditions. This study examined the agreement between self-reported and health administrative data.A randomly selected cohort of participants aged 25-75 years recruited by telephone from the general population of Quebec reported on the presence of 1 or more chronic conditions from (...) a candidate list of 12 conditions: diabetes, hypertension, thyroid disorder, any cardiac disease, cancer diagnosis in the previous 5 years (including melanoma but excluding other skin cancers), asthma, osteoarthritis, rheumatoid arthritis or lupus, osteoporosis, chronic obstructive pulmonary disease, intestinal disease and hypercholesterolemia. We also used health administrative data from Quebec's universal health insurance provider to identify participants' chronic conditions. Unique identifiers allowed

2017 CMAJ open

195. Development of newborn screening connect (NBS connect): a self-reported patient registry and its role in improvement of care for patients with inherited metabolic disorders Full Text available with Trip Pro

, interactive health tracking systems, and professional support tools are described. In addition, to examine the ability of NBS Connect to generate data that guides hypothesis-driven research, data pertaining to age at diagnosis, bone health, and skin conditions in individuals with PKU were assessed. The objective of this paper is to describe the development of NBS Connect and highlight its data, resources and research contributions.In September 2016, NBS Connect had 442 registered participants: 314 (71 (...) Development of newborn screening connect (NBS connect): a self-reported patient registry and its role in improvement of care for patients with inherited metabolic disorders Newborn Screening Connect (NBS Connect) is a web-based self-reported patient registry and resource for individuals and families affected by disorders included in the newborn screening panel. NBS Connect was launched in 2012 by Emory University after years of planning and grassroots work by professionals, consumers

2017 Orphanet journal of rare diseases

196. Reduced Positive Emotion and Underarousal are Uniquely Associated with Subclinical Depression Symptoms: Evidence from Psychophysiology, Self-report, and Symptom Clusters Full Text available with Trip Pro

to examine whether the underarousal, low positive emotion, heightened negative emotion, or emotion context insensitivity model of emotional dysfunction in subclinical depressive symptoms received greatest support. Postauricular reflex and skin conductance response potentiation for pleasant minus neutral pictures (measuring low positive emotion), overall skin conductance magnitude and late positive potential (LPP) amplitude (measuring underarousal), and pleasant minus aversive valence ratings (measuring (...) Reduced Positive Emotion and Underarousal are Uniquely Associated with Subclinical Depression Symptoms: Evidence from Psychophysiology, Self-report, and Symptom Clusters Multiple models of aberrant emotional processing in depression have been advanced. However, it is unclear which of these models best applies to emotional disturbances in subclinical depressive symptoms. The current study employed a battery of psychophysiological measures and emotional ratings in a picture-viewing paradigm

2017 Psychophysiology

197. Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Seve

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Seve Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis (...) , or Moderately to Severely Active Crohn's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects

2017 Clinical Trials

198. Biofeedback-based Relaxation Training or Self-alert Training to Alleviate Fatigue in Multiple Sclerosis Patients.

) will be done. The examination will be completed by a long-time vigilance task. Before and after the vigilance task the current fatigue status will be assessed using a visual analogue scale. It is hypothesised that especially the biofeedback-based self-alert training has a positive effect on fatigue and the vigilance performance in multiple sclerosis patients, as it increases the ectodermal activity and increases the sympathetic activation. It was shown that phasic changes of the skin resistance (...) patients using a between groups design. Furthermore, the relation of fatigue in multiple sclerosis patients and autonomic potentials as well as the performance in a vigilance task will be examined. The relaxation training is based on the principle of progressive muscle relaxation according to Jacobsen. The patient is asked to tense all muscles in their face and perceive consciously the relaxation afterwards according to verbal cues. In the self-alert training condition, the patient will hear verbal

2017 Clinical Trials

199. A Self-Management Energy Conservation Program for Cancer-Related Fatigue

) Praboromarajchanok Institute, Ministry of Public Health, Thailand Information provided by (Responsible Party): Wipasiri Naraphong, University of Michigan Study Details Study Description Go to Brief Summary: The purpose of this pilot study is to examine a 12-week self-management energy conservation program (ECAM)'s effects on fatigue, and secondarily on sleep, physical activity, anxiety and depression, self-efficacy, and beliefs about fatigue in a group of Thai women with breast cancer who are undergoing (...) A Self-Management Energy Conservation Program for Cancer-Related Fatigue A Self-Management Energy Conservation Program for Cancer-Related Fatigue - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Self

2017 Clinical Trials

200. "When risk communication backfires: Randomized controlled trial on self-affirmation and reactance to personalized risk feedback in high-risk individuals": Correction to Schüz, Schüz, and Eid (2013). (Abstract)

of the self-system to maintain integrity. In this article, we examine whether a self-affirmation manipulation can mitigate defensive responses to personalized visual risk feedback in the skin cancer prevention context (ultraviolet [UV] photography), and whether the effects pertain to individuals with high behavioral risk status (high personal relevance of tanning).We conducted a full-factorial randomized controlled trial (N = 292; age 11-71) following a 2 * 2 design (UV photo yes/no, self-affirmation yes (...) "When risk communication backfires: Randomized controlled trial on self-affirmation and reactance to personalized risk feedback in high-risk individuals": Correction to Schüz, Schüz, and Eid (2013). Reports an error in "When risk communication backfires: Randomized controlled trial on self-affirmation and reactance to personalized risk feedback in high-risk individuals" by Natalie Schüz, Benjamin Schüz and Michael Eid (Health Psychology, 2013[May], Vol 32[5], 561-570). Several errors appear

2017 Health psychology : official journal of the Division of Health Psychology, American Psychological Association Controlled trial quality: uncertain

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