How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

24,726 results for

Second Impact Syndrome

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Emerging and re-emerging human infectious diseases: A systematic review of the role of wild animals with a focus on public health impact

new infectious agents with unknown virulent potential. In conclusion, the monitoring of these diseases and adequate preparation for possible epidemics and pandemics are fundamental conditions for the mitigation of their future impact. The zoonotic threat of these etiological agents and the impact on public health can be enormous as shown by the ongoing epidemic of 2019 novel coronavirus (2019- nCoV) infections. "> Impact Factor 2018: 1.772 (@Clarivate Analytics) 5-Year Impact Factor: 1.772 (...) Emerging and re-emerging human infectious diseases: A systematic review of the role of wild animals with a focus on public health impact Emerging and re-emerging human infectious diseases: A systematic review of the role of wild animals with a focus on public health impact Cupertino MC, Resende MB, Mayer NA, Carvalho LM, Siqueira-Batista R - Asian Pac J Trop Med Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research

2020 Covid-19 Ad hoc papers

2. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Full Text available with Trip Pro

as the second choice if Troponin I/T were not provided) were extracted from the identified studies (Table and Fig. ). The primary outcome measure was to compare the prevalence of comorbidities and impact on cardiac injury in ICU and Non-ICU cases (severe and non-severe data as the second choice if ICU data was not provided). Cochrane Collaboration’s tool was followed to assess the risk of bias. Table 1 Number, age, sex and cardiovascular metabolic diseases of patients of the 6 included studies Data (...) Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China | SpringerLink Advertisement Search Search SpringerLink Search Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China , , , , , , , & ( 2020 ) 9984 Accesses 3 Citations 19 Altmetric Abstract Background Studies have reminded that cardiovascular metabolic comorbidities made patients more susceptible to suffer 2019

2020 Covid-19 Ad hoc papers

3. Second Generation Antidepressants for Pediatric patients with Major Depressive Disorder and Anxiety Disorder

Second Generation Antidepressants for Pediatric patients with Major Depressive Disorder and Anxiety Disorder Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time (...) for the purposes of research or private study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners? own terms and conditions. TITLE: Second Generation

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4. Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases

Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases Technical Brief Number 34 RTechnical Brief Number 34 Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases Prepared for: Agency for Healthcare Research and Quality (...) the effect of community health worker certification on asthma, diabetes, cardiovascular disease, and maternal-child health outcomes. • There are differing opinions about the usefulness and impact of community health worker certification. • Additional research is needed to determine effect of certification on community health worker service delivery and workforce development and to identify best practices for instituting certification programs. iii This report is based on research conducted by the Johns

2020 Effective Health Care Program (AHRQ)

5. EAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke

is increasing in this group [1]. Stroke is a heterogeneous condition with a variety of underlying mechanisms and causes. The risk of stroke is a?ected by non-modi?able (e.g.age,familyhistory)andpotentiallymodi?ablefac- tors (e.g. hypertension, current smoking, alcohol con- sumption, obesity, diabetes, lack of physical activity, psychosocialstressanddepression)[2]. Sleep–wake disorders (SWDs) are very frequent in the general population and have a major impact on performance, quality of life as well (...) EAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke EAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke C. L. A. Bassetti a,b, *, W. Randerath c, *, L. Vignatelli d , L. Ferini-Strambi e , A.-K. Brill f , M. R. Bonsignore g , L. Grote h , P. Jennum i , D. Leys j , J. Minnerup k , L. Nobili l , T. Tonia m , R. Morgan n , J. Kerry o , R. Riha p,q , W. T. McNicholas r,s,t,† and V. Papavasileiou u,v,† a Neurology Department

2020 European Academy of Neurology

6. Impact of Paclitaxel-Eluting Balloons Compared to Second-Generation Drug-Eluting Stents for of In-Stent Restenosis in a Primarily Acute Coronary Syndrome Population Full Text available with Trip Pro

Impact of Paclitaxel-Eluting Balloons Compared to Second-Generation Drug-Eluting Stents for of In-Stent Restenosis in a Primarily Acute Coronary Syndrome Population The place of drug-eluting balloons (DEB) in the treatment of in-stent restenosis (ISR) is not well-defined, particularly in a population of all-comers with acute coronary syndromes (ACS).Compare the clinical outcomes of DEB with second-generation drug-eluting stents (DES) for the treatment of ISR in a real-world population (...) with a high proportion of ACS.A retrospective analysis of consecutive patients with ISR treated with a DEB compared to patients treated with a second-generation DES was performed. The primary endpoint was a composite of major adverse cardiovascular events (MACE: all-cause death, non-fatal myocardial infarction, and target lesion revascularization). Comparisons were performed using Cox proportional hazards multivariate adjustment and Kaplan-Meier analysis with log-rank.The cohort included 91 patients

2017 Arquivos brasileiros de cardiologia

7. Impact on spina bifida screening of shifting prenatal Down syndrome maternal serum screening from the second trimester to the first. (Abstract)

Impact on spina bifida screening of shifting prenatal Down syndrome maternal serum screening from the second trimester to the first. Shifting screening for trisomy 21 to the first trimester has resulted in the loss of maternal serum alpha-fetoprotein screening for spina bifida. The aim of this study was to study the impact on open spina bifida prenatal screening.We reviewed prenatally diagnosed cases of spina bifida over three years: 2009 (only second-trimester screening, MSM2T), 2010

2017 Prenatal diagnosis

8. Psychobiological impact of speaking a second language in healthy young men. Full Text available with Trip Pro

Psychobiological impact of speaking a second language in healthy young men. The use of second languages is ubiquitous in modern societies. Despite many benefits, there is also evidence for this to cause or exacerbate stress (e.g. in the form of foreign language anxiety). The aim of the present study was to examine to which extent speaking a second language increases acute psychobiological stress in a social context. A total of N = 63 healthy Swiss males were randomly allocated to one of two (...) conditions: completing the Trier Social Stress Test (TSST) in Swiss German (their first language) vs. standard German (perceived as a second language). Repeated measures of self-reported stress, anxiety, salivary cortisol, and heart rate were obtained. Participants speaking standard German showed significantly larger cortisol increases in response to the TSST when compared to those speaking Swiss German (F(1, 61) = 5.53, p = .022, eta2 = .083). The two groups did not differ in terms of self-reported

2019 Stress (Amsterdam, Netherlands) Controlled trial quality: uncertain

9. Second Impact Syndrome

Second Impact Syndrome Second Impact Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Second Impact Syndrome Second Impact (...) Syndrome Aka: Second Impact Syndrome From Related Chapters II. Epidemiology Uncommon to rare, but with devastating consequences Appears limited to children and adolescents Although adults with multiple s may develop chronic tic encephalopathy (CTE) CTE, by contrast, results in a chronic neurodegenerative disorder with and features III. Pathophysiology Results from repeated s over a short period of time Rapid and diffuse cerebral edema with no effective treatment (does not respond to manitol) IV. Course

2018 FP Notebook

10. Second and Third Trimester Vaginal Bleeding

Second and Third Trimester Vaginal Bleeding Date of origin: 1996 Last review date: 2013 ACR Appropriateness Criteria ® 1 Second and Third Trimester Bleeding American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Second and Third Trimester Bleeding Variant 1: No other signs or symptoms. Radiologic Procedure Rating Comments RRL* US pregnant uterus transabdominal 9 Ensure visualization of placenta, inferior placental margin, and cervix from internal to external os (...) : 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate *Relative Radiation Level ACR Appropriateness Criteria ® 2 Second and Third Trimester Bleeding Clinical Condition: Second and Third Trimester Bleeding Variant 3: Placenta previa diagnosed on prior US. Radiologic Procedure Rating Comments RRL* US pregnant uterus transabdominal 9 If the cervix, specifically internal cervical os and inferior placental margin, is not visualized transabdominally, perform transvaginal

2020 American College of Radiology

11. The impact of extending the second stage of labor to prevent primary cesarean section on maternal and neonatal outcomes. Full Text available with Trip Pro

The impact of extending the second stage of labor to prevent primary cesarean section on maternal and neonatal outcomes. A low rate of primary cesarean delivery is expected to reduce some of the major complications that are associated with a repeat cesarean delivery, such as uterine rupture, adhesive placental disorders, hysterectomy, and even maternal death. Since 2014, and in alignment with the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine, we (...) changed our approach to labor dystocia, defined as abnormal progression of labor, by allowing a longer duration of the second stage of labor.To examine the effect of prolonging the second stage of labor on the rate of cesarean delivery, and maternal and neonatal outcomes.In a historical control group, we compared maternal and neonatal outcomes over 2 periods. Period I (9300 patients): from May 2011 until April 2014, when a prolonged second stage in nulliparous women was considered after 3 hours

2018 American Journal of Obstetrics and Gynecology

12. Second-Generation Antipsychotics in Adolescent Psychiatric Patients: Metabolic Effects and Impact of an Early Weight Change to Predict Longer Term Weight Gain. Full Text available with Trip Pro

Second-Generation Antipsychotics in Adolescent Psychiatric Patients: Metabolic Effects and Impact of an Early Weight Change to Predict Longer Term Weight Gain. To examine the metabolic profile of adolescents at baseline and to determine the potential predictive power of a 1-month weight gain (WG) on weight changes during longer term second-generation antipsychotic (SGA) treatment.A retrospective chart review study, including patients between 13 and 18 years of age and treated with SGA (...) ) for a WG >15% after 3 months. After adjusting for potential confounders, a threshold of WG >4% was found as being the best predictor.A worrisome prevalence of metabolic disorders was observed in an adolescent psychiatric cohort. In such patients, a WG >4% during the first month of treatment should raise concerns about weight controlling strategies. Further research is needed to confirm the present results and to determine the impact of a 1-month WG on a 1-year weight change.

2018 Journal of Child and Adolescent Psychopharmacology

13. Severe adverse events impact overall survival and costs in elderly patients with advanced non-small cell lung cancer on second-line therapy. (Abstract)

Severe adverse events impact overall survival and costs in elderly patients with advanced non-small cell lung cancer on second-line therapy. Elderly patients with advanced non-small lung cancer (aNSCLC) represent a high-risk patient population due to disease burden, comorbidities, and performance status, particularly after progressing on first-line therapy. Among elderly patients who receive second-line therapy, treatment related toxicities can have substantial impact on both clinical (...) and economic outcomes. This study assessed the impact of severe adverse events (AEs) during second-line therapy on overall survival (OS) and all-cause heathcare costs in elderly with aNSCLC.Patients with aNSCLC aged ≥65 years who initiated second-line chemotherapy/targeted therapy were identified in the SEER-Medicare database (2007-2011). Fifty-seven AEs were identified by literature review and consultation with two oncologists. Severe AEs were defined as AEs that required a hospitalization and were

2018 Lung Cancer

14. Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma Full Text available with Trip Pro

Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma 29367648 2018 08 29 2018 11 13 2044-5385 8 1 2018 01 25 Blood cancer journal Blood Cancer J Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma. 1 10.1038/s41408-017-0043-6 Tanba Kazuna K Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan. Kyoto Clinical Hematology Study Group, Kyoto, Japan. Chinen (...) , Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan. Kyoto Clinical Hematology Study Group, Kyoto, Japan. eng Clinical Trial Letter Research Support, Non-U.S. Gov't 2018 01 25 United States Blood Cancer J 101568469 2044-5385 IM Aged Aged, 80 and over Disease-Free Survival Female Humans Lymphoma, Large B-Cell, Diffuse diagnosis mortality therapy Male Middle Aged Neoplasms, Second Primary diagnosis mortality therapy Retrospective Studies Survival Rate 2017 08 29 2017 11 29 2017

2018 Blood cancer journal

15. Long-term negative impact of an inappropriate first antiepileptic medication on the efficacy of a second antiepileptic medication in mice. Full Text available with Trip Pro

epilepsy (BS/Orl). Mice received a first appropriate or inappropriate AED followed by the same appropriate AED. Our data demonstrate that an inappropriate first AED has a negative impact on the long-term efficacy of a second appropriate AED. This work supports the necessity to effectively diagnose epileptic syndromes prior to medication use, particularly in children, in order to prevent the deleterious effects of an inappropriate initial AED.Wiley Periodicals, Inc. © 2018 International League Against (...) Long-term negative impact of an inappropriate first antiepileptic medication on the efficacy of a second antiepileptic medication in mice. Childhood absence epilepsy (CAE) is one of the most frequent epilepsies in infancy. The first-line recommended therapy for CAE is based on the prescription of the narrow-spectrum ethosuximide and the broad-spectrum valproic acid, which have similar efficacy in the first 12 months. Nevertheless, some antiepileptic drugs (AEDs) may worsen seizure duration

2018 Epilepsia

16. Comparison of different methods of treating impacted permanent first or second molars and factors that influence the treatment outcome: A systematic review.

Comparison of different methods of treating impacted permanent first or second molars and factors that influence the treatment outcome: A systematic review. Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) species); sex (stratified per sex); duration of index ischemia (linear); stem cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease

2020 PROSPERO

17. Role of second-hand smoke (SHS)-induced proteostasis/autophagy impairment in pediatric lung diseases Full Text available with Trip Pro

Role of second-hand smoke (SHS)-induced proteostasis/autophagy impairment in pediatric lung diseases Exposure to second-hand tobacco smoke (SHS) is one of the prime risk factors for chronic lung disease development. Smoking during pregnancy may lead to birth defects in the newborn that include pulmonary dysfunction, increased susceptibility to opportunistic pathogens, or initiation of childhood respiratory manifestations such as bronchopulmonary dysplasia (BPD). Moreover, exposure to SHS (...) in early childhood can have negative impact on lung health, although the exact mechanisms are unclear. Autophagy is a crucial proteostatic mechanism modulated by cigarette smoke (CS) in adult lungs. Here, we sought to investigate whether SHS exposure impairs autophagy in pediatric lungs.Pregnant C57BL/6 mice were exposed to room air or SHS for 14 days. The newborn pups were subsequently exposed to room air or SHS (5 h/day) for 1 or 14 days, and lungs were harvested. Soluble and insoluble protein

2017 Molecular and cellular pediatrics

18. Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association | Circulation: Cardiovascular Genetics Search Hello Guest! Login to your account Email Password Keep me logged in Search February 2019 January 2019 This site uses cookies. By continuing (...) to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Potential Impact and Study Considerations of Metabolomics in Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association , MD, MMSc, MPH, Chair , MD, MHS, FAHA, Co-Chair , PhD , MD , PhD , MD, FAHA , PhD , MD , PhD, MPH , and MD, FAHA MD, PhDon behalf of the American Heart Association Council on Functional Genomics and Translational Biology; Council

2017 American Heart Association

19. EGFR mutation testing to determine eligibility for access to PBS subsidised osimertinib second line therapy in patients with locally advanced or metastatic NSCLC

) (Liu Y et al 2017) which assessed the prognostic impact of acquired T790M mutation status on post-progression survival, finding that a T790M mutation in tumour tissue was a positive prognostic factor for survival. The ESCs noted that these differences are consistent with the likely different spectrum of disease in those supplying a plasma sample, usually because a rebiopsy of the primary tumour is not possible because of risks to the patient. These patients are more likely to have a high tumour (...) EGFR mutation testing to determine eligibility for access to PBS subsidised osimertinib second line therapy in patients with locally advanced or metastatic NSCLC 1 Public Summary Document Application No. 1407- EGFR mutation testing to determine eligibility for access to PBS subsidised osimertinib second line therapy in patients with locally advanced or metastatic NSCLC Applicant: AstraZeneca Pty Ltd Date of MSAC consideration: MSAC 74 th Meeting, 22-23 November 2018 MSAC 71 st Meeting, 23

2018 Medical Services Advisory Committee

20. WITHDRAWN: Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease. (Abstract)

WITHDRAWN: Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease. Randomized trials have demonstrated that adding a drug to a single-agent or to a two-agent regimen increased the tumor response rate in patients with advanced non-small cell lung cancer (NSCLC), although its impact on survival remains controversial.To evaluate the clinical benefit of adding a drug to a single-agent or two-agent chemotherapy regimen in terms of tumor response (...) < 0.001) in favor of the doublet regimen. The median survival ratio was 0.83 (95% CI 0.79 to 0.89, P < 0.001). An increase also was observed in the tumor response rate (OR 0.66, 95% CI 0.58 to 0.75, P < 0.001) in favor of the triplet regimen, but not for one-year survival (OR 1.01, 95% CI 0.85 to 1.21, P = 0.88). The median survival ratio was 1.00 (95% CI 0.94 to 1.06, P = 0.97).Adding a second drug improved tumor response and survival rate. Adding a third drug had a weaker effect on tumor response

2012 Cochrane

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>