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141. Orbits, Vision and Visual Loss

head without IV contrast May Be Appropriate ??? CT head without and with IV contrast Usually Not Appropriate ??? CT orbits without and with IV contrast Usually Not Appropriate ??? X-ray orbit Usually Not Appropriate ? ACR Appropriateness Criteria ® 3 Orbits, Vision and Visual Loss Variant 3: Suspected orbital cellulitis, uveitis, or scleritis. Initial imaging. Procedure Appropriateness Category RRL CT orbits with IV contrast Usually Appropriate ??? MRI orbits without and with IV contrast Usually (...) in approximately 80% of cases [20]. Radiography Orbital or skull radiographs are insufficient to detect pathology in patients presenting with proptosis and have primarily been supplanted by CT. Variant 3: Suspected orbital cellulitis, uveitis, or scleritis. Initial imaging. Patients presenting with symptoms and signs of orbital cellulitis (postseptal cellulitis) are often referred for imaging to assess for complications including intraorbital abscess, intracranial involvement, and vascular compromise

2017 American College of Radiology

142. American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty

/ml, vasculitis (other than mild cutaneous vasculitis), including pulmonary hemorrhage, myocarditis, lupus pneumonitis, severe myositis (with muscle weakness, not just high enzymes), lupus enteritis (vasculitis), lupus pancreatitis, cholecystitis, lupus hepatitis, protein-losing enteropathy, malabsorption, orbital in?ammation/myositis, severe keratitis, posterior severe uveitis/retinal vasculitis, severe scleritis, optic neuritis, anterior ischemic optic neuropathy (derived from the SELENA–SLEDAI

2017 American College of Rheumatology

143. Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer

absorption. Symptoms such as ocular pain or loss of vision may be due to serious inflammatory conditions such as uveitis or scleritis and should be promptly evaluated by an ophthalmologist. Qualifying Statements for Recommendation 6 The risk of ONJ increases with frequency, dose, and duration of bisphosphonate administration. Risk can be reduced with appropriate screening prior to treatment and modification of dental care. Risk of ONJ when bisphosphonates are administered, as suggested in Recommendation (...) , pyrexia, and acute-phase reaction. Serious ocular or ophthalmic adverse effects such as uveitis, scleritis, and episcleritis are extremely rare but may lead to blindness if untreated. The Tel Aviv trial reported scleritis in one patient treated with zoledronic acid; serious ocular adverse events were not reported in the other trials in the current literature review. Symptoms such as ocular pain or loss of vision should be evaluated by an ophthalmologist - ; immediate treatment with steroid eye drops

2017 American Society of Clinical Oncology Guidelines

144. Severe panuveitis with relapsing polychondritis (Full text)

was found to have sensorineural deafness. He was diagnosed with relapsing polychondritis after a laryngoscopic examination.Twelve months after the diagnosis, scleritis and panuveitis developed in his left eye, and his visual acuity fell to 20/2000. We performed pars plana vitrectomy with silicone oil tamponade on his left eye. After the vitrectomy, the inflammation of the left eye was resolved.and importance: Ophthalmologist should be aware that severe panuveitis with vitreous opacities may

2018 American journal of ophthalmology case reports PubMed

145. Management of inadvertent needle penetration resulting in subretinal triamcinolone acetonide and retinal detachment (Full text)

Management of inadvertent needle penetration resulting in subretinal triamcinolone acetonide and retinal detachment To report management of inadvertent needle penetration during subtenons triamcinolone acetonide administration resulting in retinal detachment.A 71-year-old female with history of diabetes, hypothyroidism, and mild myopia underwent subtenons triamcinolone acetonide (TA) injection in the right eye for nodular scleritis. There was unexpected patient movement concurrent

2018 American journal of ophthalmology case reports PubMed

146. Orbital implant exposure after Acanthamoeba panophthalmitis (Full text)

Orbital implant exposure after Acanthamoeba panophthalmitis Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male.After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis

2018 American journal of ophthalmology case reports PubMed

147. Characteristics of inflammatory eye disease associated with hidradenitis suppurativa (Full text)

to lack of data. The mean age at the diagnosis of HS and IED was 42.1 and 43.6 years, respectively. Thirteen patients had uveitis (65%), six had scleritis (30%), and one had peripheral ulcerative keratitis. Thirteen out of 20 patients (65%) had multiple autoimmune and/or inflammatory comorbidities, including inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, and lupus. Seven patients (35%) did not have any comorbid inflammatory/autoimmune conditions.One-third

2018 European journal of rheumatology PubMed

148. Usefulness of B-scan ocular ultrasound images for diagnosis of optic perineuritis (Full text)

visit to our clinic, she still complained of blurred vision. She was found to have mild vitreous cells in the left eye and optic disc swelling in both eyes. However, the choroidal folds had already resolved in both eyes. B-scan ultrasound images displayed the optic nerve sheath as a highly reflective circle with shadowing around the optic disc in both eyes and scleral thickening in the left eye with fluid in sub-Tenon's space. Bilateral optic perineuritis with posterior scleritis seemed highly

2018 American journal of ophthalmology case reports PubMed

150. Amitriptyline for pain control in scleritis may help to avoid excessive steroid use in selected cases: a case report (Full text)

Amitriptyline for pain control in scleritis may help to avoid excessive steroid use in selected cases: a case report Pain in scleritis may be difficult to control with conventional immuno-suppressive regimes. Amitriptyline may be an effective option in those circumstances.A 41-year-old woman presented with scleritis and eye pain that was refractory to treatment with steroid and immunosuppressive agents. Effective pain relief and reduction of steroid dose was only achieved after starting (...) amitriptyline.Amitriptyline may be an effective option for pain control in case with scleritis which might otherwise require unnecessarily large doses of immunosuppression.

2009 Cases journal PubMed

151. Intraocular (Uveal) Melanoma Treatment (PDQ®): Health Professional Version

(iris melanoma), blurred vision (ciliary body melanoma), or markedly decreased visual acuity caused by secondary retinal detachment (choroidal melanoma). Serous detachment of the retina may occur. If extensive detachment occurs, secondary angle-closure glaucoma occasionally develops. Clinically, several lesions simulate uveal melanoma, including metastatic carcinoma, posterior scleritis, and benign tumors, such as nevi and hemangiomas.[ ] Anatomy of the eye. Diagnosis Careful examination

2018 PDQ - NCI's Comprehensive Cancer Database

152. Are Probiotics A Panacea Or Pure Hype?: The Gullible Gastroenterologist Weighs In

diet, and am practically a vegetarian. My chronic pain is posterior scleritis of the eye, a very painful and chronic problem. Maybe just anecdotal but the pain has significantly dimenished since starting this diet. The microbiome testing company, Microba, offers a 3 monthly suerveillance program. An exceptionally comprehensive report advises on how to improve diet to encourage the good guys, and to have the bad guys die out. See for more. I’m just glad I got to use probiotics before

2019 The Skeptical Cardiologist

153. Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients. (Full text)

the general population of Korea.A total of 13,925 CD patients and 29,356 UC patients were identified. CD and UC patients were different in terms of demographics and utilization of medication. Among the 17 EIMs investigated, pyoderma gangrenosum, osteomalacia, Sweet syndrome, and scleritis were observed in very few patients. The SPRs were greater than 1 for all EIMs. Aphthous stomatitis, rheumatoid arthritis, and osteoporosis were highly prevalent in both CD and UC patients, but the SPRs of the EIMs were

2018 PLoS ONE PubMed

154. Long-term efficacy and tolerability of TNFα inhibitors in the treatment of non-infectious ocular inflammation: an 8-year prospective surveillance study. (Full text)

Long-term efficacy and tolerability of TNFα inhibitors in the treatment of non-infectious ocular inflammation: an 8-year prospective surveillance study. To report the efficacy and tolerability of antitumour necrosis factor-alpha therapy (TNF inhibitors [TNFi]) in the management of non-infectious ocular inflammation, including uveitis and scleritis, in adult patients over an 8-year period.This is a prospective cohort study of infliximab and adalimumab in the treatment of non-infectious ocular (...) inflammatory disease. 43 of 85 adult patients on TNFi (34 infliximab, 9 adalimumab) for ≥1 year with non-infectious uveitis or scleritis were followed from 2006 to 2014. Clinical assessments, medication, adverse events and history of steroid rescues were collected at 6 monthly intervals. General quality of life (Short Form Health Survey (SF-36)) and visual quality of life (Vision-related quality of life Core Measure (VCM1)) were assessed annually. Outcome measures included rate of sustained remission, rate

2019 British Journal of Ophthalmology PubMed

155. Ocular involvement in granulomatosis with polyangiitis: A single-center cohort study on 63 patients. (PubMed)

nomenclature definitions, we identified those with ocular involvement and a subsequent follow up in our center.The prevalence of ocular involvement in our GPA series was 38.6%; 63 patients were analysed with a median follow-up of 50.5 months (IQR: 17.8-82.8). Scleritis (18 patients, 26.8%) and episcleritis (18 patients, 26.8%) were the most common ophthalmologic manifestations, followed by orbital disease (13 patients, 20.6%). Bilateral involvement and visual acuity loss was seen in 29.1% and 16.7

2019 Autoimmunity reviews

156. Predictive risk factors for exudative retinal detachment after vitrectomy for proliferative diabetic retinopathy. (PubMed)

laser photocoagulation); ocular trauma; systemic diseases; ocular diseases; uveitis; scleritis; tumor; congenital ocular disorders; or others.Included were 205 eyes of 169 patients, of whom 18 (8.78%) developed ERD with varying degrees of exudative choroidal detachment after 1 to 3 days. Binary logistic regression showed the following association with the development of ERD: lower serum albumin concentration (P = .001); without intravitreal anti-vascular endothelial growth factor (anti-VEGF) drug

2019 Medicine

157. Aminobisphosphonate-associated orbital and ocular inflammatory disease. (PubMed)

and a literature review to differentiate disease presentation and course between various aminobisphosphonates.Eight patients from our institution (6 women and 2 men, median age 62 years) were included. The used drugs were zoledronate, alendronate and risedronate. The most common clinical presentation was conjunctival hyperaemia/chemosis. Scleritis was the most common manifestation, followed by diffuse orbital inflammation and anterior uveitis. Ultrasound aided in diagnosis in all our patients

2019 Acta ophthalmologica

159. Sarilumab (Kevzara) - for treating adults with moderate to severe rheumatoid arthritis

, characteristically bone marrow (anemia), eye (scleritis, episcleritis), lung (interstitial pneumonitis, pleuritis), cardiac (pericarditis) and skin (nodules, leukocytoclastic vasculitis). Systemic inflammation is characterized by laboratory abnormalities, such as anemia, elevated erythrocyte sedimentation rate, fibrinogen and C-reactive protein (CRP) and by clinical symptoms of fatigue, weight loss, muscle atrophy in affected joint areas. The presence of polyclonal high titre rheumatoid factors and anti-Cyclic

2017 European Medicines Agency - EPARs

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