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Scleritis

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81. Scleritis (Overview)

Scleritis (Overview) Scleritis: Practice Essentials, Background, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIyODMyNC1vdmVydmlldw== processing > Scleritis Updated: Nov 01, 2018 Author (...) : Manolette R Roque, MD, MBA, FPAO; Chief Editor: Andrew A Dahl, MD, FACS Share Email Print Feedback Close Sections Sections Scleritis Overview Practice Essentials Scleral inflammation (scleritis) may occur in one or both eyes. Pain is a hallmark symptom. Signs of scleritis include focal or diffuse redness or violaceous discoloration, initial scleral thickening, late scleral thinning, nodules, and scleral necrosis. It may be associated with keratitis, iritis, glaucoma, and exudative retinal detachment

2014 eMedicine.com

82. Scleritis (Treatment)

Scleritis (Treatment) Scleritis Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIyODMyNC10cmVhdG1lbnQ= processing > Scleritis Treatment (...) & Management Updated: Nov 01, 2018 Author: Manolette R Roque, MD, MBA, FPAO; Chief Editor: Andrew A Dahl, MD, FACS Share Email Print Feedback Close Sections Sections Scleritis Treatment Medical Care Treatment of scleritis almost always requires systemic therapy. Patients with an associated disease, such as rosacea, gout, atopy, or infection, need disease-specific treatment. Systemic therapy complements aggressive topical corticosteroid therapy, generally with difluprednate, prednisolone or loteprednol

2014 eMedicine.com

83. Scleritis (Treatment)

Scleritis (Treatment) Scleritis in Emergency Medicine Treatment & Management: Approach Considerations, Emergency Department Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODA5MTY2LXRyZWF0bWVudA== processing (...) > Scleritis in Emergency Medicine Treatment & Management Updated: Dec 31, 2018 Author: Theodore J Gaeta, DO, MPH, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP Share Email Print Feedback Close Sections Sections Scleritis in Emergency Medicine Treatment Approach Considerations Primary complaint of atraumatic eye pain rarely necessitates prehospital care, other than expedient transport to the ED. Take care not to overlook serious comorbidity. If global perforation is suspected, shield the eye

2014 eMedicine Emergency Medicine

84. Scleritis (Overview)

Scleritis (Overview) Scleritis in Emergency Medicine: Practice Essentials, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODA5MTY2LW92ZXJ2aWV3 processing > Scleritis in Emergency Medicine (...) Updated: Dec 31, 2018 Author: Theodore J Gaeta, DO, MPH, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP Share Email Print Feedback Close Sections Sections Scleritis in Emergency Medicine Overview Practice Essentials Scleritis is an inflammatory disease that affects the sclera; it may be localized, nodular, or diffuse. [ ] It may involve the anterior (visible segment) and/or posterior segments of the eye and manifest with redness of the eye and severe eye pain [ , ] Patients with isolated

2014 eMedicine Emergency Medicine

85. Scleritis (Follow-up)

Scleritis (Follow-up) Scleritis in Emergency Medicine Treatment & Management: Approach Considerations, Emergency Department Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODA5MTY2LXRyZWF0bWVudA== processing (...) > Scleritis in Emergency Medicine Treatment & Management Updated: Dec 31, 2018 Author: Theodore J Gaeta, DO, MPH, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP Share Email Print Feedback Close Sections Sections Scleritis in Emergency Medicine Treatment Approach Considerations Primary complaint of atraumatic eye pain rarely necessitates prehospital care, other than expedient transport to the ED. Take care not to overlook serious comorbidity. If global perforation is suspected, shield the eye

2014 eMedicine Emergency Medicine

86. Subconjunctival dexamethasone implant for non-necrotizing scleritis Full Text available with Trip Pro

Subconjunctival dexamethasone implant for non-necrotizing scleritis The purpose of this study is to report the management of non-necrotizing anterior scleritis with a single-dose subconjunctival 0.7 mg dexamethasone implant (Ozurdex®, Allergan, Inc., CA, USA). Six patients with clinical diagnosis of non-necrotizing anterior scleritis (diffuse, sectorial, and nodular) were submitted to subconjunctival injection of dexamethasone implant. The injection was performed under topical anesthesia (...) recurrence was noted in the 6-month follow-up in a patient with rheumatoid arthritis and non-necrotizing diffuse scleritis and was treated with oral steroids. No patient developed ocular hypertension or any kind of complications during the follow-up period, except for subconjunctival hemorrhage.Dexamethasone implant was safely and effectively used as a local therapy for non-necrotizing scleritis.

2013 Journal of ophthalmic inflammation and infection

87. Incidence of Scleritis and Episcleritis: Results From the Pacific Ocular Inflammation Study. Full Text available with Trip Pro

Incidence of Scleritis and Episcleritis: Results From the Pacific Ocular Inflammation Study. To ascertain the incidence of scleritis and episcleritis in a Hawaiian population and describe variations by age, sex, and race.Retrospective, population-based cohort study.All electronic medical records for enrollees in Kaiser Permanente Hawaii (n = 217,061) from January 1, 2006 to December 31, 2007 were searched for International Classification of Diseases, 9th Edition (ICD-9) codes associated (...) with ocular inflammation. Chart review was conducted to verify a clinical diagnosis of scleritis or episcleritis. Confirmed cases were used to calculate incidence rates per 100,000 person-years. Ninety-five percent confidence intervals (CI) were calculated for each incidence rate, including age-, sex-, and race-specific rates, using bias-corrected Poisson regression. To assess for confounding, a multivariate analysis adjusting for age, sex, and race was also performed.Of 217,061 eligible patients, 17

2013 American Journal of Ophthalmology

88. Necrotizing scleritis after strabismus surgery in thyroid eye disease. (Abstract)

Necrotizing scleritis after strabismus surgery in thyroid eye disease. Surgically induced necrotizing scleritis, which can lead to potentially devastating consequences, is a rare sequela to many types of ocular surgeries. We describe a 58-year-old woman who developed necrotizing scleritis following strabismus surgery for thyroid ophthalmopathy. Tectonic corneal patch grafting resulted in a favorable outcome. Copyright © 2013 American Association for Pediatric Ophthalmology and Strabismus

2013 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

89. Infectious Pseudomonas scleritis after strabismus surgery. (Abstract)

Infectious Pseudomonas scleritis after strabismus surgery. Scleral inflammation and necrosis are rare but serious complications of ocular surgery. We present a case of Pseudomonas infectious scleritis following strabismus surgery with an exuberant, presumably sterile endophthalmitis in an immunocompromised 62-year-old man that was responsive to topical and oral antibiotics. Copyright © 2013 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights

2013 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

90. Scleritis: Immunopathogenesis and molecular basis for therapy. (Abstract)

Scleritis: Immunopathogenesis and molecular basis for therapy. Scleritis is a heterogeneous group of diseases characterized by inflammation of the sclera, which may be due to local or systemic infections or immune mediated diseases. Numerous studies over the last decade have lead to significant progress in understanding the pathogenesis and treatment of this severe and potentially blinding disease. Immunological investigations of non-infectious scleritis and associated diseases have indicated (...) that scleritis is an autoimmune disease and studies on the nature of the local inflammatory response have revealed the prominent role of T and B cells and cytokines, such as TNF-alpha, which in turn has resulted in clinical trials showing the effectiveness of local steroid treatment, anti-TNF and anti-B cell therapy. The widespread use of imaging has led to the realization that posterior scleritis is more common than previously recognized and testing for ANCA antibodies has revealed the prominent role

2013 Progress in Retinal and Eye Research

91. Gevokizumab for Active Scleritis

Gevokizumab for Active Scleritis Gevokizumab for Active Scleritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Gevokizumab for Active Scleritis The safety and scientific validity of this study (...) ) ( National Eye Institute (NEI) ) Study Details Study Description Go to Brief Summary: Background: - Scleritis is the inflammation of the white outer coating of the eye, known as the sclera. In severe cases, it can cause blindness. It is commonly associated with autoimmune disorders such as rheumatoid arthritis. Mild scleritis can be treated with drugs such as ibuprofen. More severe scleritis may need oral steroids or immunosuppressive treatments; however, these treatments can cause side effects

2013 Clinical Trials

92. Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis

Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01958567 Recruitment Status : Completed First Posted : October 9, 2013 Last Update Posted : September 1, 2014 Sponsor: The Eye Center and The Eye Foundation for Research

2013 Clinical Trials

93. Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report Full Text available with Trip Pro

Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report 24232311 2014 07 23 2018 11 13 1476-5454 28 1 2014 Jan Eye (London, England) Eye (Lond) Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report. 104-6 10.1038/eye.2013.215 Dean W H WH Ophthalmology Department, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK. Turner S A SA Ophthalmology Department, Gloucestershire Hospitals NHS Foundation Trust (...) , Cheltenham, UK. McNaught A I AI 1] Ophthalmology Department, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK [2] Cranfield University, Bedfordshire, UK. eng Case Reports Letter 2013 11 15 England Eye (Lond) 8703986 0950-222X 0 Alkylating Agents 50SG953SK6 Mitomycin IM Aged Alkylating Agents administration & dosage Chronic Disease Female Follow-Up Studies Glaucoma, Open-Angle etiology surgery Humans Intraocular Pressure Mitomycin administration & dosage Sclera pathology Scleritis

2013 Eye

94. Scleritis

Scleritis Scleritis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Scleritis Scleritis Aka: Scleritis , Nodular Scleritis (...) , Necrotizing Scleritis From Related Chapters II. Epidemiology Rare III. Pathophysiology Severe l inflammation Variations Nodular Scleritis Necrotizing Scleritis (most destructive) Anterior Scleritis (deep to ) Posterior Scleritis (overlying ) IV. Causes Idiopathic in 50% of cases (most common cause) Accounts for up to one third of Scleritis cases Scleritis occurs in 4-10% of RA cases (previously known as ) Infectious (uncommon) Pseudomonas V. Symptoms involving one or both eyes Blurred vision Photophobia

2015 FP Notebook

95. Combined anterior and posterior scleritis associated with central retinal vein occlusion: a case report Full Text available with Trip Pro

Combined anterior and posterior scleritis associated with central retinal vein occlusion: a case report The purpose of this study is to report an uncommon presentation of anterior and posterior scleritis with central retinal vein occlusionWe report a 30-year-old female presenting with unilateral anterior and posterior scleritis with concurrent central retinal vein occlusion, the subsequent work-up, and the management. The patient presented with decreased vision and extraocular and intraocular (...) inflammatory signs in the left eye.At presentation, the best corrected visual acuity in the right eye (OD) was 20/20 and left eye (OS) was perception of light, with inaccurate projection of rays in all quadrants. Intraocular pressure was 12 mmHg in both eyes. OS showed mild proptosis with lid edema. Ocular movements were free and full in both eyes. The bulbar conjunctiva showed nodular anterior scleritis. OS showed mild vitreous haze with an exudative detachment at the posterior pole, disc edema

2012 Journal of ophthalmic inflammation and infection

96. Imaging Studies in a Case of Infectious Scleritis after Pterygium Excision Full Text available with Trip Pro

Imaging Studies in a Case of Infectious Scleritis after Pterygium Excision A 44-year-old woman presented with a painful red eye for 2 weeks. Ultrasound biomicroscopy and optical coherence tomography were instrumental in the diagnosis and management of this case of infectious scleritis associated with previous pterygium excision complicated by choroidal and retinal detachments.

2012 Middle East African journal of ophthalmology

97. Necrobiotic xanthogranuloma and chronic lymphocytic leukemia of the conjunctiva masquerading as scleritis and uveitis Full Text available with Trip Pro

Necrobiotic xanthogranuloma and chronic lymphocytic leukemia of the conjunctiva masquerading as scleritis and uveitis This report describes a unique case of coexisting necrobiotic xanthogranuloma and chronic lymphocytic leukemia in a patient presenting with scleritis and uveitis. A 53-year-old Caucasian man diagnosed with anterior uveitis and scleritis for the prior year was referred to our uveitis clinic for further evaluation. Prior uveitis/scleritis workup performed by the referring (...) ophthalmologist was negative. Examination demonstrated unilateral uveitis and posterior scleritis along with bilateral conjunctival lesions. Incisional biopsy of the conjunctiva was carried out. The excised tissue was sent fresh for histopathologic studies. Slit-lamp examination revealed bilateral yellow-white bulbar conjunctival lesions, 1+ conjunctival injection OU, stellate keratic precipitates OS with 25 cells per high-powered field. Funduscopic examination was significant for subretinal fluid OS

2012 Clinical ophthalmology (Auckland, N.Z.)

98. Clinical Features and Presentation of Infectious Scleritis from Herpes Viruses: A Report of 35 Cases. (Abstract)

Clinical Features and Presentation of Infectious Scleritis from Herpes Viruses: A Report of 35 Cases. To describe clinical features and presentation of infectious scleritis resulting from herpes viruses.Retrospective case series.Thirty-five patients out of 500 with scleritis.We reviewed the electronic health records of 500 patients with scleritis, 35 of whom were diagnosed with herpes virus infection, seen at 2 tertiary referral centers. We studied the clinical features and ocular complications (...) of this subset of patient with scleritis.Correlation between classification, severity, and symptoms (i.e., pain) and diagnosis of herpetic-associated scleritis. Vision loss, presence of associated uveitis, keratitis, glaucoma, or systemic disease were documented over the follow-up period. Other outcome measures included epidemiologic data: age, gender, laterality, visual acuity, duration of symptoms, and underlying systemic or ocular diseases.Of 500 patients with scleritis, 47 (9.4%) had an underlying

2012 Ophthalmology

99. Sirolimus Injections for Autoimmune Scleritis

Sirolimus Injections for Autoimmune Scleritis Sirolimus Injections for Autoimmune Scleritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sirolimus Injections for Autoimmune Scleritis (ISAS) The safety (...) Center (CC) ( National Eye Institute (NEI) ) Study Details Study Description Go to Brief Summary: Background: Autoimmune scleritis is an inflammatory disease that affects the white outer part of the eye. It is associated with immune system disorders like rheumatoid arthritis. It can cause blindness in severe cases. Most treatments for scleritis involve steroid or immune-suppressing drugs, but these can cause side effects in the whole body. Sirolimus is a drug used to help prevent transplant rejection

2012 Clinical Trials

100. Management of Rhodotorula scleritis Full Text available with Trip Pro

Management of Rhodotorula scleritis 22975653 2013 05 07 2018 11 13 1476-5454 26 12 2012 Dec Eye (London, England) Eye (Lond) Management of Rhodotorula scleritis. 1587 10.1038/eye.2012.181 Pradhan Z S ZS Jacob P P eng Case Reports Letter 2012 09 14 England Eye (Lond) 8703986 0950-222X 0 Antifungal Agents 0 Ophthalmic Solutions 7XU7A7DROE Amphotericin B IM Adult Amphotericin B administration & dosage Antifungal Agents administration & dosage Diagnosis, Differential Eye Infections, Fungal (...) diagnosis drug therapy microbiology Female Humans Instillation, Drug Ophthalmic Solutions Rhodotorula isolation & purification Sclera microbiology pathology Scleritis diagnosis drug therapy microbiology 2012 9 15 6 0 2012 9 15 6 0 2013 5 8 6 0 ppublish 22975653 eye2012181 10.1038/eye.2012.181 PMC3522827 Cornea. 2000 Jan;19(1):34-9 10632006 Clin Microbiol Rev. 2003 Oct;16(4):730-97 14557297 Eye (Lond). 2009 Feb;23(2):255-61 18219336 Rev Iberoam Micol. 2008 Sep 30;25(3):135-40 18785780 Br J Ophthalmol

2012 Eye

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