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Scleritis

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801. Refractory scleritis due to Wegener's granulomatosis. Full Text available with Trip Pro

Refractory scleritis due to Wegener's granulomatosis. 3577127 1987 05 28 2018 11 13 0093-0415 146 3 1987 Mar The Western journal of medicine West. J. Med. Refractory scleritis due to Wegener's granulomatosis. 361-3 Hodges E J EJ Turner S S Doud R B RB eng Case Reports Journal Article Research Support, Non-U.S. Gov't United States West J Med 0410504 0093-0415 IM Aged Female Granulomatosis with Polyangiitis pathology Humans Inflammation Sclera 1987 3 1 1987 3 1 0 1 1987 3 1 0 0 ppublish 3577127

1987 Western Journal of Medicine

802. Infliximab to Treat Non-Infectious Scleritis

Infliximab to Treat Non-Infectious Scleritis Infliximab to Treat Non-Infectious Scleritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Infliximab to Treat Non-Infectious Scleritis The safety (...) : This small, preliminary study will examine whether multiple infusions of infliximab (Remicade® (Registered Trademark)) can control inflammation in patients with active scleritis. The sclera is the tough white outer coat enclosing the eyeball. Infliximab is a combination of part human and part mouse proteins that block a natural body protein called tumor necrosis factor (TNF). TNF appears to be involved in scleritis, and stopping its action may help reduce the inflammation in the disease. The drug has

2003 Clinical Trials

803. Bilateral non-specific orbital inflammation (orbital “pseudotumour”), posterior scleritis, and anterior uveitis associated with hypothyroidism in a child Full Text available with Trip Pro

Bilateral non-specific orbital inflammation (orbital “pseudotumour”), posterior scleritis, and anterior uveitis associated with hypothyroidism in a child 12140225 2002 09 26 2018 11 13 0007-1161 86 8 2002 Aug The British journal of ophthalmology Br J Ophthalmol Bilateral non-specific orbital inflammation (orbital "pseudotumour"), posterior scleritis, and anterior uveitis associated with hypothyroidism in a child. 936 Uddin J M JM Rennie C A CA Moore A T AT eng Case Reports Letter Review (...) England Br J Ophthalmol 0421041 0007-1161 IM Adolescent Female Humans Hypothyroidism complications Orbital Pseudotumor complications Scleritis complications Uveitis, Anterior complications 9 2002 7 26 10 0 2002 9 27 6 0 2002 7 26 10 0 ppublish 12140225 PMC1771216 Ophthalmology. 1999 Dec;106(12):2380-6 10599675 Ophthalmology. 1981 Jun;88(6):565-74 7267028 Ophthalmology. 1982 Sep;89(9):1040-8 7177569 Surv Ophthalmol. 1988 Mar-Apr;32(5):297-316 3043740 Eye (Lond). 1995;9 ( Pt 5):570-4 8543074 J Pediatr

2002 The British journal of ophthalmology

804. Exudative retinal detachment and posterior scleritis associated with massive scleral thickening and calcification treated by scleral decompression. Full Text available with Trip Pro

Exudative retinal detachment and posterior scleritis associated with massive scleral thickening and calcification treated by scleral decompression. A 66-year-old man presented with massive bilateral scleral thickening and calcification associated with a unilateral exudative retinal detachment which did not respond to systemic anti-inflammatory agents including steroids and cyclophosphamide but improved with scleral resection. This patient shows the features of both posterior scleritis

1992 The British journal of ophthalmology

805. Posterior scleritis with retinal vasculitis and choroidal and retinal infarction. Full Text available with Trip Pro

Posterior scleritis with retinal vasculitis and choroidal and retinal infarction. 8025079 1994 08 09 2018 11 13 0007-1161 78 5 1994 May The British journal of ophthalmology Br J Ophthalmol Posterior scleritis with retinal vasculitis and choroidal and retinal infarction. 410-2 Frost N A NA Department of Ophthalmology, University of Leicester, Leicester Royal Infirmary. Sparrow J M JM Rosenthal A R AR eng Case Reports Journal Article England Br J Ophthalmol 0421041 0007-1161 IM Adult Choroid (...) blood supply Drug Therapy, Combination Female Humans Infarction complications Retinal Diseases complications Retinal Vessels Scleritis complications drug therapy Visual Acuity 1994 5 1 1994 5 1 0 1 1994 5 1 0 0 ppublish 8025079 PMC504799 Trans Ophthalmol Soc U K. 1975 Jul;95(2):297-300 1064228 Eye (Lond). 1988;2 ( Pt 3):267-77 3402623 Am J Ophthalmol. 1981 Jun;91(6):697-705 6166197

1994 The British journal of ophthalmology

806. Bilateral necrotising scleritis with marginal corneal ulceration after cataract surgery in a patient with vasculitis. Full Text available with Trip Pro

Bilateral necrotising scleritis with marginal corneal ulceration after cataract surgery in a patient with vasculitis. The onset of bilateral necrotising scleritis and marginal corneal ulceration after cataract surgery are described in a patient with diffuse vasculitis syndrome. The finding of immune complexes in this patient's tissue biopsy suggests that they are the cause of a localised primary vasculitis triggered by surgical inflammation. Clinically, this patient's marginal corneal (...) ulceration preceded the scleral necrosis. A past history of orbital inflammation may have been due to a posterior scleritis. The corneal ulcerations responded to conjunctival debridement and steroids. The scleral necrosis was unresponsive to the 2 anti-inflammatory preparations tried, and the patient eventually went into remission while off all treatment.

1980 The British journal of ophthalmology

807. Intrascleral dissemination of infectious scleritis following pterygium excision Full Text available with Trip Pro

Intrascleral dissemination of infectious scleritis following pterygium excision To assess the clinical pictures, possible pathogenesis, management, and therapy of patients with infectious scleritis associated with multifocal scleral abscesses following pterygium excision.The records of patients with infectious scleritis after pterygium excision who developed multifocal scleral abscesses presenting from 1988 to the end of 1995 were reviewed. Early culture of abscesses was performed, and topical

1998 The British journal of ophthalmology

808. Posterior scleritis with optic perineuritis and internal ophthalmoplegia Full Text available with Trip Pro

Posterior scleritis with optic perineuritis and internal ophthalmoplegia 9274419 1997 09 11 2015 11 19 0007-1161 81 6 1997 Jun The British journal of ophthalmology Br J Ophthalmol Posterior scleritis with optic perineuritis and internal ophthalmoplegia. 514 Ohtsuka K K Hashimoto M M Miura M M Nakamura Y Y eng Case Reports Letter England Br J Ophthalmol 0421041 0007-1161 0 Organometallic Compounds 7A314HQM0I Pentetic Acid K2I13DR72L Gadolinium DTPA IM Adult Female Gadolinium DTPA Humans Magnetic (...) Resonance Imaging methods Ophthalmoplegia etiology Optic Neuritis etiology Organometallic Compounds Pentetic Acid analogs & derivatives Scleritis complications diagnosis 1997 6 1 1997 6 1 0 1 1997 6 1 0 0 ppublish 9274419 PMC1722214

1997 The British journal of ophthalmology

809. Scleritis associated with acute febrile neutrophilic dermatosis (Sweet's syndrome) Full Text available with Trip Pro

Scleritis associated with acute febrile neutrophilic dermatosis (Sweet's syndrome) 9602638 1998 06 02 2008 11 21 0007-1161 82 3 1998 Mar The British journal of ophthalmology Br J Ophthalmol Scleritis associated with acute febrile neutrophilic dermatosis (Sweet's syndrome) 328-9 Chen T C TC Goldstein D A DA Tessler H H HH Quinn J P JP Bautista C M CM eng Case Reports Letter England Br J Ophthalmol 0421041 0007-1161 IM Aged Humans Male Scleritis etiology Sweet Syndrome complications 1998 5 29

1998 The British journal of ophthalmology

810. Changes at the periphery of a lesion in necrotising scleritis: anterior segment fluorescein angiography correlated with electron microscopy. Full Text available with Trip Pro

Changes at the periphery of a lesion in necrotising scleritis: anterior segment fluorescein angiography correlated with electron microscopy. Anterior segment fluorescein angiography in scleral disease reveals highly characteristic changes in the vasculature of the anterior segment associated with necrotising scleritis. The vaso-obliterative changes discovered in this investigation have been correlated with the histopathology in a patient who had to have tissue replaced. Light and electron

1985 The British journal of ophthalmology

811. Microscopical studies of necrotising scleritis. I. Cellular aspects. Full Text available with Trip Pro

Microscopical studies of necrotising scleritis. I. Cellular aspects. Light and electron microscopy were used to examine tissue excised during surgery from eight patients with advanced destructive scleral disease. These comprised two cases of scleromalacia perforans, three cases of anterior necrotising scleritis alone or in conjunction with other systemic diseases, and three cases in which scleritis developed following ocular surgery. It was not possible to distinguish between these three

1984 The British journal of ophthalmology

812. Haemophilus influenzae associated scleritis Full Text available with Trip Pro

Haemophilus influenzae associated scleritis To describe the clinical course and treatment of Haemophilus influenzae associated scleritis.Retrospective case series.Three patients developed scleritis associated with ocular H influenzae infection. Past medical history, review of systems, and laboratory testing for underlying collagen vascular disorders were negative in two patients. One patient had arthritis associated with an antinuclear antibody titre of 1:160 and a Westergren erythrocyte (...) sedimentation rate of 83 mm in the first hour. Each patient had ocular surgery more than 6 months before developing scleritis. Two had cataract extraction and one had strabismus surgery. Nodular abscesses associated with areas of scleral necrosis were present in each case. Culture of these abscesses revealed H influenzae in all patients. Treatments included topical, subconjunctival, and systemic antibiotics. Scleral inflammation resolved and visual acuity improved in each case.H influenzae infection may

1999 The British journal of ophthalmology

813. Nodular scleritis in a patient with sarcoidosis Full Text available with Trip Pro

Nodular scleritis in a patient with sarcoidosis 12642326 2003 05 23 2018 11 13 0007-1161 87 4 2003 Apr The British journal of ophthalmology Br J Ophthalmol Nodular scleritis in a patient with sarcoidosis. 507-8 Heiligenhaus A A Department of Ophthalmology, St Franziskus Hospital, Muenster, Germany. arnd.heiligenhaus@t-online.de Michel D D Koch J M JM eng Case Reports Journal Article England Br J Ophthalmol 0421041 0007-1161 IM Biopsy Female Humans Lung Diseases complications pathology Middle (...) Aged Sarcoidosis complications pathology Sclera pathology Scleritis complications pathology 2003 3 19 4 0 2003 5 24 5 0 2003 3 19 4 0 ppublish 12642326 PMC1771607 Trans Ophthalmol Soc U K. 1976 Apr;96(1):133-9 1070842 Am J Ophthalmol. 1995 Nov;120(5):677-9 7485375 Am J Ophthalmol. 1986 Sep 15;102(3):297-301 3752193

2003 The British journal of ophthalmology

814. Surgically induced diffuse scleritis: comparison of incidence in phacoemulsification and conventional extracapsular cataract extraction Full Text available with Trip Pro

Surgically induced diffuse scleritis: comparison of incidence in phacoemulsification and conventional extracapsular cataract extraction 12034697 2002 07 26 2018 11 13 0007-1161 86 6 2002 Jun The British journal of ophthalmology Br J Ophthalmol Surgically induced diffuse scleritis: comparison of incidence in phacoemulsification and conventional extracapsular cataract extraction. 701 Sen J J Kamath G G GG Clearkin L G LG eng Letter England Br J Ophthalmol 0421041 0007-1161 IM Aged Cataract (...) Extraction adverse effects Humans Middle Aged Phacoemulsification adverse effects Retrospective Studies Risk Factors Scleritis etiology 2002 5 30 10 0 2002 7 27 10 1 2002 5 30 10 0 ppublish 12034697 PMC1771156 Br J Ophthalmol. 1999 Dec;83(12):1336-40 10574810 Eye (Lond). 1994;8 ( Pt 3):292-7 7958033 Ophthalmology. 1993 Sep;100(9):1372-6 8371926

2002 The British journal of ophthalmology

815. Orbital myositis in scleritis. Full Text available with Trip Pro

Orbital myositis in scleritis. To investigate the association between scleritis and myositis.Retrospective, non-comparative case series. Records and ultrasonograms were examined of 132 patients, with a diagnosis of episcleritis or scleritis, who attended the ophthalmology department at Leiden University Medical Center between 1997 and 2000. 103 were eligible for comprehensive examination. Medical records were evaluated. Ultrasonography was performed in all patients diagnosed with episcleritis (...) or scleritis. Clinical features, precipitating factors, systemic associations, ocular complications, treatment, and outcome of each patient were assessed.Of the 103 patients, 27 (26.2%) had episcleritis and 76 (73.8%) had scleritis. Myositis was found to be present in 11 patients. It was present in 14.5% of all patients with scleritis and 30.5% of those in whom the posterior sclera was affected. The presence of the associated myositis did not worsen the visual prognosis and the presence of myositis

2003 British Journal of Ophthalmology

816. Scleritis and other ocular side effects associated with pamidronate disodium. (Abstract)

Scleritis and other ocular side effects associated with pamidronate disodium. To evaluate reported cases of scleritis and other ocular side effects associated with pamidronate disodium, with emphasis on previously unreported cases of scleritis.Observational case series.Case reports from the National Registry of Drug-Induced Ocular Side Effects (Casey Eye Institute), the Food and Drug Administration, the World Health Organization, and the literature were reviewed to determine possible adverse (...) ocular side effects associated with pamidronate disodium. The World Health Organization's Causality Assessment Guide was used to categorize an adverse drug reaction.Seventeen cases of unilateral scleritis and one case of bilateral scleritis occurred, usually within 6 hours to 2 days after intravenous pamidronate disodium. Six patients had positive rechallenge testing with the scleritis occurring after a repeat drug exposure. Other ocular side effects with positive rechallenge data, associated

2003 American Journal of Ophthalmology

817. Severe scleritis and urticarial lesions. (Abstract)

Severe scleritis and urticarial lesions. To report the first known case of bilateral scleritis in a patient with hypocomplementemic urticarial vasculitis.Interventional case report.Medical and ophthalmic history, results of physical and ophthalmic examinations, laboratory data, and histologic and immunopathologic examination were reviewed and results recorded.A 67-year-old man who presented with eye redness and pain, rash, arthralgia, and malaise was found to have hypocomplementemic urticarial

2002 American Journal of Ophthalmology

818. Multifocal nodular episcleritis and scleritis with undiagnosed Hodgkin's lymphoma. (Abstract)

Multifocal nodular episcleritis and scleritis with undiagnosed Hodgkin's lymphoma. To report the case of a patient with undiagnosed Hodgkin's lymphoma who presented with coexistent unilateral nodular episcleritis and scleritis.Interventional case report and literature reviewReview of clinical history, laboratory findings, histology of episcleral and cervical lymph node biopsies, and follow-up.A 20-year-old female presented with a 5-month history of redness and pain in her left eye (...) , with associated symptoms of dyspnea, malaise, and fever. The patient was found to have multifocal nodular episcleritis and scleritis that was not responsive to topical steroids or systemic nonsteroidal anti-inflammatory treatment. Laboratory tests subsequently revealed evidence of systemic inflammation, and radiologic studies showed extensive mediastinal and cervical adenopathy. A cervical lymph node biopsy showed Reed-Sternberg cells and a chronic lymphocytic infiltrate consistent with nodular sclerosing

2003 Ophthalmology

819. Mycophenolate mofetil for the treatment of scleritis. (Abstract)

Mycophenolate mofetil for the treatment of scleritis. To evaluate the usefulness of mycophenolate mofetil (MMF) (CellCept, Roche, Nutley, NJ), an antimetabolite immunosuppressant with a selective antiproliferative effect on T and B lymphocytes, for the treatment of scleritis.Retrospective, noncomparative case series.Eight patients with scleritis treated with MMF in a tertiary referral center.Review of the clinical records of patients evaluated at the National Eye Institute and prescribed MMF (...) scleritis, two with necrotizing scleritis with inflammation, one with nodular anterior scleritis, and one with nodular anterior and posterior scleritis, were identified. Mycophenolate mofetil administration was initiated as a steroid-sparing agent in 4 patients with controlled scleritis and as an additional immunosuppressive agent in 4 patients with active scleritis receiving concomitant treatment with prednisone and cyclosporine or methotrexate. In 3 of the 4 patients started on MMF as a steroid

2003 Ophthalmology

820. Anterior segment indocyanine green angiography in anterior scleritis and episcleritis. (Abstract)

Anterior segment indocyanine green angiography in anterior scleritis and episcleritis. To evaluate the pattern of anterior segment indocyanine green (ICG) angiography in episcleritis and scleritis.Prospective comparative (paired-eye) observational case series.Twenty subjects presenting clinical diseases compatible with episcleritis or scleritis.Anterior segment ICG angiography was performed according to a standard protocol in subjects presenting either episcleritis or scleritis. Photographs (...) ICG angiography in episcleritis and scleritis.Twenty subjects with a mean age of 43 +/- 15 years (7 male, 13 female) were enrolled in the study. Thirteen subjects had anterior scleritis (7 nodular, 5 diffuse, and 1 scleromalacia perforans), and 7 subjects had episcleritis. Only 1 out of 7 subjects with episcleritis showed a slight ICG leakage (a score of one), whereas all subjects with scleritis had ICG leakage scores of one or more (P = 0.0005, Fisher exact test).ICG angiography of the anterior

2003 Ophthalmology

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