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Sclera

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2261. Internal sclerostomy using laser ablation of dyed sclera in glaucoma patients: a pilot study. (PubMed)

Internal sclerostomy using laser ablation of dyed sclera in glaucoma patients: a pilot study. Twelve eyes of 12 patients with refractory glaucoma were treated with internal sclerostomy using laser ablation of dyed sclera. The technique involves iontophoretic impregnation of the sclera at the limbal region with 1% methylene blue and subsequent delivery of a pulsed dye laser beam to the stained area through a goniolens. The red wavelength of 664 nm generated by the laser is maximally absorbed (...) by the stained sclera and creates a through and through sclerostomy. Successful complete sclerostomy was achieved in seven eyes (58.3%) but there was some reduction of intraocular pressure (IOP) in all cases. Mean prelaser IOP (of all 12 eyes) was 36.6 mm Hg and 1 hour after therapy it was reduced to 20.0 mm Hg. At the end of the follow-up period (mean 16 months) the mean IOP was 23.7 mm Hg; five eyes (41%) maintained their IOP below 22 mm Hg, and the average number of medications per eye came down from 3.25

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1993 The British journal of ophthalmology

2262. Dermatan sulphate proteoglycans from sclera examined by rotary shadowing and electron microscopy. (PubMed)

Dermatan sulphate proteoglycans from sclera examined by rotary shadowing and electron microscopy. Two dermatan sulphate-containing proteoglycans from bovine sclera were examined by rotary shadowing and electron microscopy, and the results were compared with previous biochemical findings. Both the large iduronate-poor proteoglycan (PGI) and the small iduronate-rich proteoglycan (PGII) possessed a globular proteinaceous region. Whereas PGI had a branched extension from the globular region

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1987 Biochemical Journal

2263. [Prospective study of surgical therapy of pterygium: bare sclera technique vs. free conjunctiva-limbus transplant]. (PubMed)

[Prospective study of surgical therapy of pterygium: bare sclera technique vs. free conjunctiva-limbus transplant]. Many techniques of pterygium surgery with various rates of recurrence are described in the literature. We report on the outcome after pterygium excision with bare-sclera technique compared with free transplantation of limbal conjunctiva. We used the bare-sclera technique in 21 eyes and performed free transplantation of conjunctiva in 34 eyes. The duration of follow-up was 14 (...) months. In patients operated with the bare-sclera technique there were significantly more recurrences (eight vs four, P < 0.025) and cases of development of pyogenic granuloma (four eyes vs no eyes, P < 0.01). In patients with primary surgery and free limbal transplant we found no case of recurrence, but the bare-sclera technique was associated with a recurrence rate of 35.5% (P < 0.01). We recommend free limbal conjunctival transplantation even in patients with primary surgery of a pterygium.

1996 Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft

2264. Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision. (PubMed)

Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision. To compare success rates of conjunctival autografting and bare sclera excision for primary and recurrent pterygium in the tropics and to evaluate risk factors for pterygium recurrence.A prospective, controlled clinical trial was performed in which 123 primary and 34 recurrent pterygia, matched for age and pterygium morphology, were randomized in 2 separate (...) studies to receive either bare sclera excision or conjunctival autograft. The surgical procedures were performed by one surgeon and reviewed at 1, 3, 6, and 12 months after surgery by an independent observer. Pterygium morphology was clinically graded as atrophic, intermediate, or fleshy according to an assessment of pterygium translucency. Risk factors were assessed using likelihood ratio tests. Weibull curves were used to estimate recurrence rates allowing for the interval censoring.In the group

1997 Archives of ophthalmology

2265. Meta-analysis on the recurrence rates after bare sclera resection with and without mitomycin C use and conjunctival autograft placement in surgery for primary pterygium. (PubMed)

Meta-analysis on the recurrence rates after bare sclera resection with and without mitomycin C use and conjunctival autograft placement in surgery for primary pterygium. Bare sclera resection with and without use of mitomycin C and conjunctival autograft placement are three surgical techniques currently in use for the treatment of primary pterygium. The purpose of this study was to determine through a meta-analysis the risk for postoperative pterygium recurrence comparing the three surgical (...) of pterygium recurrence. These were calculated utilising the Mantel-Haenszel method.Five eligible studies with an adequate quality score were retrieved, three comparing bare sclera resection with and without mitomycin C use, one comparing bare sclera resection with conjunctival autograft placement, and one comparing both. The pooled odds ratio for pterygium recurrence in patients who had only bare sclera resection was 6.1 (95% confidence intervals, 1.8 to 18.8) compared with the patients who had

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1998 British Journal of Ophthalmology

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