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Saucerization Biopsy

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1. Saucerization Biopsy

Saucerization Biopsy Saucerization Biopsy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Saucerization Biopsy Saucerization Biopsy (...) Aka: Saucerization Biopsy II. Definition technique III. Indications Consider where needed in regions at risk of IV. Technique Similar preparation and lesion marking as for Thick tissue sample obtained via curved blade (e.g. Dermablade) Depth extends at least to mid- and in some cases into sub-cutaneous fat V. Efficacy May offer faster and better cosmesis than with VI. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term

2018 FP Notebook

2. Saucerization Biopsy

Saucerization Biopsy Saucerization Biopsy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Saucerization Biopsy Saucerization Biopsy (...) Aka: Saucerization Biopsy II. Definition technique III. Indications Consider where needed in regions at risk of IV. Technique Similar preparation and lesion marking as for Thick tissue sample obtained via curved blade (e.g. Dermablade) Depth extends at least to mid- and in some cases into sub-cutaneous fat V. Efficacy May offer faster and better cosmesis than with VI. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term

2015 FP Notebook

3. A prospective study evaluating the utility of a 2-mm biopsy margin for complete removal of histologically atypical (dysplastic) nevi. (PubMed)

margin of normal skin.We conducted a prospective study of a saucerization method using a defined 2-mm margin in patients undergoing biopsy of a pigmented skin lesion.We performed 151 biopsies in 138 patients. Overall, 137 of 151 lesions subjected to biopsy (90.7%) were melanocytic: 86 DN (57.0%), 40 nevi without atypia (26.5%), and 11 melanomas (7.3%). Of 78 DN, 68 (87.2%) were removed with clear histopathologic margins (8 DN were excluded because of inadequate processing). There was no clinical (...) A prospective study evaluating the utility of a 2-mm biopsy margin for complete removal of histologically atypical (dysplastic) nevi. Complete removal of individual dysplastic nevi (DN) is often accomplished by a second surgical procedure after the initial biopsy. The choice to perform the second procedure is strongly influenced by histopathologic margin status of the initial biopsy specimen.To evaluate the clinical and histopathologic outcomes of in toto biopsy of DN using a predetermined

2017 Journal of American Academy of Dermatology

4. Prospective Study of 2 mm Margins for the Biopsy of Dysplastic Nevi

York University School of Medicine Study Details Study Description Go to Brief Summary: Non-interventional study to evaluate the utility of removing Dysplastic Nevi with a defined 2 mm margin. Condition or disease Intervention/treatment Dysplastic Nevi Procedure: Saucerization biopsy Detailed Description: This is a prospective, observational study to evaluate the utility of removing Dysplastic Nevi (DN) with a defined 2 mm margin. This is a non-interventional study that will observe the pathology (...) topics: Groups and Cohorts Go to Intervention Details: Procedure: Saucerization biopsy 2 mm saucerization biopsy of dysplastic nevi Outcome Measures Go to Primary Outcome Measures : Clear margins on the histopathological sections examined after a 2 mm saucerazation biopsy. [ Time Frame: Up to 1 year ] 2 mm saucerization biopsy Secondary Outcome Measures : Nevus recurrence rate [ Time Frame: Up to 1 year ] To determine the rate of nevus recurrence within 1 year of follow-up Eligibility Criteria Go

2017 Clinical Trials

5. A comparison of current practice patterns of US dermatologists versus published guidelines for the biopsy, initial management, and follow up of patients with primary cutaneous melanoma. (PubMed)

assessing preferred biopsy methods for lesions suspicious for melanoma, margins used for excision, and recommended follow-up intervals were sent to 6177 US dermatologists (540 responding). The representative nature of the responding subset was verified by comparing their demographics to that from the American Academy of Dermatology (AAD) membership.Management varied from published guidelines. Shave biopsy (35%) was the most commonly used method followed by narrow excisional biopsy (31%), saucerization (...) A comparison of current practice patterns of US dermatologists versus published guidelines for the biopsy, initial management, and follow up of patients with primary cutaneous melanoma. Guidelines exist for the management of cutaneous malignant melanoma, but their adoption, prevalence, and impact have not yet been determined.To determine current melanoma clinical management practices of US dermatologists and the variance from guidelines that might exist.A cross-sectional e-mail survey study

2016 Journal of American Academy of Dermatology

6. Shave Biopsy

lesion above skin plane Shave tangential to skin with #15 blade or Dermablade (double-edged razor blade) Shave under lesion through and into , but not deeper (1 mm depth) Angle blade slightly to obtain upper Avoid cutting into subcutaneous tissue Must be converted to standard biopsy Remaining defect is saucer-shaped Consider using Radiofrequency to smooth edges Effective at reducing scarring risk on face Use small electrosurgical loop electrode Set unit to 1.5 or 2.0 Stabilize hand against skin (...) Shave Biopsy Shave Biopsy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Shave Biopsy Shave Biopsy Aka: Shave Biopsy , Tangential

2018 FP Notebook

7. Shave Biopsy

lesion above skin plane Shave tangential to skin with #15 blade or Dermablade (double-edged razor blade) Shave under lesion through and into , but not deeper (1 mm depth) Angle blade slightly to obtain upper Avoid cutting into subcutaneous tissue Must be converted to standard biopsy Remaining defect is saucer-shaped Consider using Radiofrequency to smooth edges Effective at reducing scarring risk on face Use small electrosurgical loop electrode Set unit to 1.5 or 2.0 Stabilize hand against skin (...) Shave Biopsy Shave Biopsy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Shave Biopsy Shave Biopsy Aka: Shave Biopsy , Tangential

2015 FP Notebook

8. The rate of melanoma transection with various biopsy techniques and the influence of tumor transection on patient survival. (PubMed)

% for saucerization biopsies. The means of disease-free survival for the control and transected groups were 911 days and 832.7 days, respectively (P value .67). Overall survival for the control group was 1073.7 days versus 1012.4 days for the transected group (P value .72).The study used a select population. The sample size of transected biopsies was limited, in turn limiting the power of the study. Residents performed the majority of biopsies.Punch and saucerization biopsies were more likely to transect tumors (...) The rate of melanoma transection with various biopsy techniques and the influence of tumor transection on patient survival. Depth of melanoma invasion is critical because it dictates patient treatment and prognosis. Recent reports indicate melanoma transection with initial biopsy does not impact patient survival; however, tumor transection can lead to misdiagnosis and inaccurate staging.This study assessed the rate of melanoma transection with various biopsy techniques and the impact of tumor

2012 Journal of American Academy of Dermatology

9. Guidelines of care for the management of cutaneous squamous cell carcinoma

Published online: January 10, 2018 Accepted: October 3, 2017 ; Expand all Collapse all Article Outline Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human cancer and has an increasing annual incidence. Although most cSCC is cured with office-based therapy, advanced cSCC poses a significant risk for morbidity, impact on quality of life, and death. This document provides evidence-based recommendations for the management of patients with cSCC. Topics addressed include biopsy (...) of this document, as is a discussion of cSCC in situ (Bowen disease). The primary focus of the guideline is on the most commonly considered and utilized approaches for the surgical and medical treatment of cSCC, but it also includes recommendations on appropriate biopsy techniques, staging, follow-up, and prevention of cSCC. A detailed discussion of specific chemotherapeutic or radiotherapeutic approaches for distant metastatic SCC falls outside the scope of this guideline. However, general recommendations

2018 American Academy of Dermatology

10. Mid borderline leprosy in type Bα Blaschko linear pattern: a rare phenomenon. (PubMed)

Mid borderline leprosy in type Bα Blaschko linear pattern: a rare phenomenon. Leprosy is a chronic granulomatous disease caused by M. leprae. It is a great imitator as it can manifest in different unusual and atypical ways. Mid borderline leprosy (BB) is an unstable form representing the immunologic midpoint in the clinical spectrum.Here, we report a case of BB leprosy having classical inverted saucer-shaped lesions elsewhere on the body with a linear psoriasiform lesion over the left forearm (...) following the lines of Blaschko. Biopsy from this lesion revealed granulomas consisting of equal admixture of epithelioid cells and macrophages without multinucleate giant cells suggesting mid borderline leprosy.Occurrence of lesions in a Blaschko linear pattern supports the role of genetic susceptibility to leprosy. The genetically vulnerable cells along the lines of Blaschko were infected while the surrounding cells remained unaffected. This explains the concept of locus minoris resistentiae due

2018 International Journal of Dermatology

12. Preoperative Evaluation and Management (Overview)

, and extensive patient evaluation is unnecessary. Some of these simple procedures include limited cryosurgery, curettage, electrosurgery, punch and saucerization biopsies, and simple excisions. However, the need for patient evaluation is greater with more complex procedures, such as dermabrasion, hair transplantation, flaps, and grafts. Certain underlying physiologic and pathophysiologic problems demand attention and caution. Medications and dietary supplements are often numerous and need to be scrutinized (...) should be allowed to clear before elective procedures are undertaken. The process of hepatic stabilization may take several weeks past the risk period of delirium tremens following alcohol withdrawal. Hepatic function is best assessed by the clinical status, the return of transaminase levels to baseline, and/or a repeat biopsy of the liver. A natural decline in hepatic function occurs with age, which is important with respect to drug metabolism. The amide class of anesthetics (eg, lidocaine

2014 eMedicine.com

13. Atypical Mole (Dysplastic Nevus) (Follow-up)

on the skin and because the risk of any one atypical mole developing malignant transformation is low, the prophylactic removal of all atypical moles does not prevent the development of melanoma and is not recommended. Changing lesions and any lesion worrisome for melanoma must be removed. A narrow-margin excisional biopsy or saucerization may be appropriate and can produce adequate tissue for histologic examination. If a suspicious mole is too large for simple excision and is in either a cosmetically (...) sensitive location or a functionally sensitive location, a limited biopsy may be considered. However, because of sampling error, the diagnosis may be inaccurate. [ ] To decrease the risk of an inaccurate diagnosis, obtaining more than one biopsy specimen should be considered. A wider saucerization or excision may be indicated if there is significant atypia and a margin involved, but data suggest that reexcision of low-grade lesions is not necessary. [ , , , , ] Previous Next: Consultations Atypical

2014 eMedicine.com

14. Juxtacortical Tumors (Diagnosis)

to enlargement of the lesion or from impingement on adjacent soft-tissue structures. On physical examination, the mass is painful, firm, and immobile. [ ] Radiographically, periosteal chondromas demonstrate variable mineralization within the lesion. A shell of new bone formation from the overlying periosteum may also be present (see the first image below). The underlying bone cortex usually is scalloped (saucerization) with various degrees of sclerosis. [ ] Cortical sclerosis is well marginated but may (...) . The possibility of higher-grade areas within dedifferentiated parosteal osteosarcoma lesions emphasizes the need for adequate sampling of the tumor at biopsy. This constitutes the dedifferentiated variant of parosteal osteosarcoma. By virtue of its low-grade nature, as seen histologically, parosteal osteosarcoma has the best prognosis of any of the variants of surface osteosarcoma, with survival rates of 80% at 20 years postoperatively in the Memorial-Sloan-Kettering series [ ] and 90% at 5 years

2014 eMedicine Surgery

15. Juxtacortical Tumors (Follow-up)

to enlargement of the lesion or from impingement on adjacent soft-tissue structures. On physical examination, the mass is painful, firm, and immobile. [ ] Radiographically, periosteal chondromas demonstrate variable mineralization within the lesion. A shell of new bone formation from the overlying periosteum may also be present (see the first image below). The underlying bone cortex usually is scalloped (saucerization) with various degrees of sclerosis. [ ] Cortical sclerosis is well marginated but may (...) . The possibility of higher-grade areas within dedifferentiated parosteal osteosarcoma lesions emphasizes the need for adequate sampling of the tumor at biopsy. This constitutes the dedifferentiated variant of parosteal osteosarcoma. By virtue of its low-grade nature, as seen histologically, parosteal osteosarcoma has the best prognosis of any of the variants of surface osteosarcoma, with survival rates of 80% at 20 years postoperatively in the Memorial-Sloan-Kettering series [ ] and 90% at 5 years

2014 eMedicine Surgery

16. Preoperative Evaluation and Management (Treatment)

, and extensive patient evaluation is unnecessary. Some of these simple procedures include limited cryosurgery, curettage, electrosurgery, punch and saucerization biopsies, and simple excisions. However, the need for patient evaluation is greater with more complex procedures, such as dermabrasion, hair transplantation, flaps, and grafts. Certain underlying physiologic and pathophysiologic problems demand attention and caution. Medications and dietary supplements are often numerous and need to be scrutinized (...) should be allowed to clear before elective procedures are undertaken. The process of hepatic stabilization may take several weeks past the risk period of delirium tremens following alcohol withdrawal. Hepatic function is best assessed by the clinical status, the return of transaminase levels to baseline, and/or a repeat biopsy of the liver. A natural decline in hepatic function occurs with age, which is important with respect to drug metabolism. The amide class of anesthetics (eg, lidocaine

2014 eMedicine.com

17. Oral Nevi (Treatment)

):43-9. . Media Gallery This biopsy-proven intramucosal nevus on the gingiva is unusual because it is not raised and has an irregular outline. Intramucosal nevus on the lower lip. This brown papule measured 0.6 cm in diameter and was only slightly raised. Melanotic macules are invariably flat. Blue nevus on the gingiva. This 1-cm saucer-shaped tan macule on the gingiva has histologic features consistent with those of a blue nevus, which is the second most common type of oral nevus. This location (...) lip presentation in a black patient and a review of the subject. NDA J . 1994 Jan-Feb. 45(1):19-23. . Ide F, Mishima K, Yamada H, Saito I, Tanaka A, Kusama K. Neurotized nevi of the oral mucosa: an immunohistochemical and ultrastructural analysis of nevic corpuscles. J Oral Pathol Med . 2007 Sep. 36(8):505-10. . Cerrato F, Wallins JS, Webb ML, McCarty ER, Schmidt BA, Labow BI. Outcomes in pediatric atypical spitz tumors treated without sentinel lymph node biopsy. Pediatr Dermatol . 2012 Jul-Aug

2014 eMedicine.com

18. Atypical Mole (Dysplastic Nevus) (Treatment)

on the skin and because the risk of any one atypical mole developing malignant transformation is low, the prophylactic removal of all atypical moles does not prevent the development of melanoma and is not recommended. Changing lesions and any lesion worrisome for melanoma must be removed. A narrow-margin excisional biopsy or saucerization may be appropriate and can produce adequate tissue for histologic examination. If a suspicious mole is too large for simple excision and is in either a cosmetically (...) sensitive location or a functionally sensitive location, a limited biopsy may be considered. However, because of sampling error, the diagnosis may be inaccurate. [ ] To decrease the risk of an inaccurate diagnosis, obtaining more than one biopsy specimen should be considered. A wider saucerization or excision may be indicated if there is significant atypia and a margin involved, but data suggest that reexcision of low-grade lesions is not necessary. [ , , , , ] Previous Next: Consultations Atypical

2014 eMedicine.com

19. Oral Nevi (Overview)

. Blue nevus on the gingiva. This 1-cm saucer-shaped tan macule on the gingiva has histologic features consistent with those of a blue nevus, which is the second most common type of oral nevus. This location is atypical because most blue nevi occur on the palate. Junctional and compound nevi are uncommon, accounting for only 3-6% and 5.9-16.5%, respectively. [ , , ] Rarer types include Spitz nevi, cellular blue nevi, congenital nevi, combined nevi, balloon cell nevi, epithelioid blue nevi, plaque (...) underwent biopsies. [ ] Sex Oral mucosal nevi have a slight female predominance (1.5:1 female-to-male ratio), except for the blue nevi type, which occurs equally in both sexes. [ ] Age The average age at diagnosis is 35 years (range, 3-85 y). [ ] Male patients tend to be a few years older than female patients. Patients with junctional and compound nevi are relatively younger, with an average age at diagnosis of 22 and 24 years, respectively. Previous Next: Prognosis Reports mainly based on case reports

2014 eMedicine.com

20. Lentigo Maligna Melanoma (Overview)

excision, saucerization, or punch biopsy, if the lesion is small enough. The specimen should include a portion of subcutaneous fat to ensure that accurate microstaging can be determined. Previous Next: Lymph Node Biopsy Sentinel lymph node biopsy is done to assess regional lymph node involvement and to decide on adjuvant therapy. This technique is indicated in all melanoma patients except those with stage 0 or stage 1A disease, that is, patients with a lesion thinner than 1 mm (see Staging (...) for development of melanoma. Previous Next: Diagnostic Considerations Distinguishing lentigo maligna from its invasive counterpart on a clinical basis continues to present diagnostic dilemmas, especially in patients who had previous therapeutic interventions such as cryotherapy. It is important to have a low threshold for biopsy of pigmented facial lesions. In a series of 85 excised lesions with a clinical diagnosis of lentigo maligna, more than 50% had invasive lentigo maligna melanoma. The following

2014 eMedicine.com

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