How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

361 results for

Rocky Mountain Spotted Fever

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Rocky Mountain spotted fever

Rocky Mountain spotted fever Rocky Mountain spotted fever - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Rocky Mountain spotted fever Last reviewed: February 2019 Last updated: August 2018 Summary Notifiable disease. Can be fatal if not treated early. Doxycycline is the drug of choice for treatment in patients of all ages and is almost always curative, especially if given in the first 5 days of illness. As the risk (...) , in contrast to infections due to other tick-borne spotted fever group rickettsiae. A history of tick bite may not be elicited in up to nearly half of cases. Definition Rocky Mountain spotted fever (RMSF) is a systemic vasculitis caused by infection with Rickettsia rickettsii , a tick-borne, gram-negative, intracellular bacterium. Biggs HM, Behravesh CB, Bradley KK, et al. Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever and other spotted fever group rickettsioses

2018 BMJ Best Practice

3. Meningoencephalitis due to spotted fever rickettsioses, including Rocky Mountain spotted fever. (Abstract)

Meningoencephalitis due to spotted fever rickettsioses, including Rocky Mountain spotted fever. The spotted fever rickettsioses (SFR), including Rocky Mountain spotted fever, are tick-borne infections with frequent neurologic involvement. High morbidity and mortality make early recognition and empiric treatment critical. Most literature on SFR meningoencephalitis predates widespread magnetic resonance imaging (MRI) utilization. To better understand the contemporary presentation and outcomes

2019 Clinical Infectious Diseases

4. A Cluster of Cases of Rocky Mountain Spotted Fever in an Area Of Colombia Not Known to be Endemic for This Disease. (Abstract)

A Cluster of Cases of Rocky Mountain Spotted Fever in an Area Of Colombia Not Known to be Endemic for This Disease. Rocky Mountain spotted fever (RMSF) has been reported in Colombia since 1937. Most recent outbreaks were in 2006-2008, followed by the absence of recognized cases. This report describes new clinical cases of RMSF and epidemiologic investigations. Medical records were reviewed, and fieldwork, serological and molecular diagnostic testing, and bacterial isolation were performed (...) . Fever, hypotension, abdominal discomfort, and rash accompanied by thrombocytopenia and leukopenia were the most characteristic manifestations. Two convalescent sera from the index case and sera from two dogs revealed high anti-spotted fever group Rickettsia antibody titers. Rickettsia rickettsii was isolated from case 4. Cases 2 and 3 were identified by epidemiological connection with the index case. Thus, a new cluster of cases of RMSF was identified in Antioquia, Colombia, with the occurrence

2019 American Journal of Tropical Medicine & Hygiene

5. Susceptibility of <i>Rickettsia rickettsii</i> to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever. (Abstract)

Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever. Rocky Mountain spotted fever (RMSF), caused by Rickettsia rickettsii, is a severe tick-borne infection endemic to the Americas. Oral doxycycline is effective, but during severe life-threatening disease, intravenous therapy is recommended. Unfortunately, intravenous formulations of doxycycline are not always available. Therefore, we aimed to determine

2019 American Journal of Tropical Medicine & Hygiene

6. Molecular Confirmation of Rocky Mountain Spotted Fever Epidemic Agent in Mexicali, Mexico. Full Text available with Trip Pro

Molecular Confirmation of Rocky Mountain Spotted Fever Epidemic Agent in Mexicali, Mexico. Since 2008, a large epidemic of Rocky Mountain spotted fever has been emerging among humans and dogs in Mexicali, adjacent to the United States in Baja California, Mexico. We molecularly confirmed the causative agent; this information can be used to study the origin and dynamics of the epidemic.

2018 Emerging Infectious Diseases

7. Septic Shock Caused by Rocky Mountain Spotted Fever in a Suburban Texas Patient with Pet Dog Exposure: A Case Report Full Text available with Trip Pro

Septic Shock Caused by Rocky Mountain Spotted Fever in a Suburban Texas Patient with Pet Dog Exposure: A Case Report BACKGROUND Rocky Mountain spotted fever (RMSF) is associated with high mortality and requires prompt identification and treatment to ensure better outcomes. CASE REPORT We describe an advanced case of RMSF in a 45-year-old female patient with pet dog exposure who presented with altered mental status, dyspnea, and ataxia progressing to septic shock and acute hypoxic respiratory

2018 The American journal of case reports

8. Medical knowledge related to Rocky Mountain spotted fever in Sonora, Mexico. (Abstract)

Medical knowledge related to Rocky Mountain spotted fever in Sonora, Mexico. Rocky Mountain spotted fever (RMSF) is a tick-borne disease with a high case-fatality rate unless diagnosed promptly and treated timely with doxycycline. Physician knowledge about presentation and treatment can improve outcomes of RMSF in endemic regions, such as Sonora in northern Mexico, where RMSF has caused 1348 non-fatal cases and 247 deaths from 2003 to 2016.A cross-sectional study was conducted with 343

2018 Transactions of the Royal Society of Tropical Medicine & Hygiene

9. The Evaluation and Management of Rocky Mountain Spotted Fever in the Emergency Department: a Review of the Literature. (Abstract)

The Evaluation and Management of Rocky Mountain Spotted Fever in the Emergency Department: a Review of the Literature. Rocky Mountain spotted fever (RMSF) is potentially deadly and can present subtly with signs and symptoms overlapping with other clinical conditions. Delayed diagnosis can be fatal.This review provides an evidence-based summary of the current data for the evaluation and management of RMSF in the emergency department.RMSF occurs through transmission of Rickettsia rickettsii (...) by an infected tick. Exposure in the United States occurs most commonly from April to September, and high-risk locations include wooded, shrubby, or grassy areas. Approximately half of patients with infection do not recall tick exposure. Symptoms can include fever, headache, photophobia, malaise, myalgias, and a petechial rash that begins on the wrists and ankles and spreads to the trunk. Rash may not occur in ≤15% of patients, and the classic triad of fever, headache, and rash is also not definitive

2018 Journal of Emergency Medicine

10. Fatal Rocky Mountain Spotted Fever along the United States-Mexico Border, 2013-2016. Full Text available with Trip Pro

Fatal Rocky Mountain Spotted Fever along the United States-Mexico Border, 2013-2016. Rocky Mountain spotted fever (RMSF) is an emerging public health concern near the US-Mexico border, where it has resulted in thousands of cases and hundreds of deaths in the past decade. We identified 4 patients who had acquired RMSF in northern Mexico and subsequently died at US healthcare facilities. Two patients sought care in Mexico before being admitted to US-based hospitals. All patients initially had (...) several nonspecific signs and symptoms, including fever, headache, nausea, vomiting, or myalgia, but deteriorated rapidly without receipt of a tetracycline-class antimicrobial drug. Each patient experienced respiratory failure late in illness. Although transborder cases are not common, early recognition and prompt initiation of appropriate treatment are vital for averting severe illness and death. Clinicians on both sides of the US-Mexico border should consider a diagnosis of RMSF for patients

2017 Emerging Infectious Diseases

11. Rocky Mountain Spotted Fever and Pregnancy: Four Cases from Sonora, Mexico. Full Text available with Trip Pro

Rocky Mountain Spotted Fever and Pregnancy: Four Cases from Sonora, Mexico. We present a series of four pregnant women with Rocky Mountain spotted fever (RMSF) that occurred in Sonora, Mexico, during 2015-2016. Confirmatory diagnoses were made by polymerase chain reaction or serological reactivity to antigens of Rickettsia rickettsii by using an indirect immunofluorescence antibody assay. Each patient presented with fever and petechial rash and was treated successfully with doxycycline. Each (...) of the women and one full-term infant delivered at 36 weeks gestation survived the infection. Three of the patients in their first trimester of pregnancy suffered spontaneous abortions. RMSF should be suspected in any pregnant woman presenting with fever, malaise and rash in regions where R. rickettsii is endemic.

2017 American Journal of Tropical Medicine & Hygiene

12. Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever Full Text available with Trip Pro

Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever Primary immune thrombocytopenia (ITP) - also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura - is an acquired thrombocytopenia caused by autoantibodies against platelet antigens. It is one of the more common causes of thrombocytopenia in otherwise asymptomatic adults. Rocky Mountain spotted fever (RMSF) is a potentially lethal, but curable, tick-borne disease. We present a case of ITP

2017 Case reports in oncology

13. Rocky Mountain spotted fever in Mexico: past, present, and future. (Abstract)

Rocky Mountain spotted fever in Mexico: past, present, and future. Rocky Mountain spotted fever, a tick-borne zoonosis caused by Rickettsia rickettsii, is among the most lethal of all infectious diseases in the Americas. In Mexico, the disease was first described during the early 1940s by scientists who carefully documented specific environmental determinants responsible for devastating outbreaks in several communities in the states of Sinaloa, Sonora, Durango, and Coahuila. These investigators (...) also described the pivotal roles of domesticated dogs and Rhipicephalus sanguineus sensu lato (brown dog ticks) as drivers of epidemic levels of Rocky Mountain spotted fever. After several decades of quiescence, the disease re-emerged in Sonora and Baja California during the early 21st century, driven by the same environmental circumstances that perpetuated outbreaks in Mexico during the 1940s. This Review explores the history of Rocky Mountain spotted fever in Mexico, current epidemiology

2017 Lancet infectious diseases

14. Rocky Mountain Spotted Fever

) These images are a random sampling from a Bing search on the term "Rocky Mountain Spotted Fever." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Rocky Mountain Spotted Fever (C0035793) Definition (MSH) An acute febrile illness caused by RICKETTSIA RICKETTSII. It is transmitted to humans by bites of infected ticks and occurs only in North and South America. Characteristics include a sudden onset with headache and chills (...) Rocky Mountain Spotted Fever Rocky Mountain Spotted Fever Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Rocky Mountain Spotted Fever

2018 FP Notebook

15. Hierarchical Bayesian Spatio–Temporal Analysis of Climatic and Socio–Economic Determinants of Rocky Mountain Spotted Fever Full Text available with Trip Pro

Hierarchical Bayesian Spatio–Temporal Analysis of Climatic and Socio–Economic Determinants of Rocky Mountain Spotted Fever This study aims to examine the spatio-temporal dynamics of Rocky Mountain spotted fever (RMSF) prevalence in four contiguous states of Midwestern United States, and to determine the impact of environmental and socio-economic factors associated with this disease. Bayesian hierarchical models were used to quantify space and time only trends and spatio-temporal interaction

2016 PloS one

16. Estimation of Rickettsia rickettsii copy number in the blood of patients 1 with Rocky Mountain spotted fever suggests cyclic diurnal trends in bacteremia. Full Text available with Trip Pro

Estimation of Rickettsia rickettsii copy number in the blood of patients 1 with Rocky Mountain spotted fever suggests cyclic diurnal trends in bacteremia. 26724989 2017 01 26 2017 10 08 1469-0691 22 4 2016 Apr Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases Clin. Microbiol. Infect. Estimation of Rickettsia rickettsii copy number in the blood of patients with Rocky Mountain spotted fever suggests cyclic (...) -743X IM Bacteremia microbiology Bacterial Load Circadian Rhythm Humans Rickettsia rickettsii isolation & purification Rocky Mountain Spotted Fever microbiology 2015 12 14 2015 12 18 2016 1 4 6 0 2016 1 5 6 0 2017 1 27 6 0 ppublish 26724989 S1198-743X(15)01086-1 10.1016/j.cmi.2015.12.019

2015 Clinical Microbiology and Infection

17. Medical and Indirect Costs Associated with a Rocky Mountain Spotted Fever Epidemic in Arizona, 2002-2011. Full Text available with Trip Pro

Medical and Indirect Costs Associated with a Rocky Mountain Spotted Fever Epidemic in Arizona, 2002-2011. Rocky Mountain spotted fever (RMSF) is an emerging public health issue on some American Indian reservations in Arizona. RMSF causes an acute febrile illness that, if untreated, can cause severe illness, permanent sequelae requiring lifelong medical support, and death. We describe costs associated with medical care, loss of productivity, and death among cases of RMSF on two American Indian

2015 American Journal of Tropical Medicine & Hygiene

18. Risk factors for fatal outcome from Rocky Mountain spotted fever in a highly endemic area: Arizona, 2002-2011. Full Text available with Trip Pro

Risk factors for fatal outcome from Rocky Mountain spotted fever in a highly endemic area: Arizona, 2002-2011. Rocky Mountain spotted fever (RMSF) is a disease that now causes significant morbidity and mortality on several American Indian reservations in Arizona. Although the disease is treatable, reported RMSF case fatality rates from this region are high (7%) compared to the rest of the nation (<1%), suggesting a need to identify clinical points for intervention.The first 205 cases from (...) providers should have a low threshold for initiating doxycycline whenever treating febrile or potentially septic patients from tribal lands in Arizona, even if an alternative diagnosis seems more likely and classic findings of RMSF are absent.Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

2015 Clinical Infectious Diseases

19. Phylogeography of Rickettsia rickettsii Genotypes Associated with Fatal Rocky Mountain Spotted Fever. Full Text available with Trip Pro

Phylogeography of Rickettsia rickettsii Genotypes Associated with Fatal Rocky Mountain Spotted Fever. Rocky Mountain spotted fever (RMSF), a tick-borne zoonosis caused by Rickettsia rickettsii, is among the deadliest of all infectious diseases. To identify the distribution of various genotypes of R. rickettsii associated with fatal RMSF, we applied molecular typing methods to samples of DNA extracted from formalin-fixed, paraffin-embedded tissue specimens obtained at autopsy from 103 case

2014 American Journal of Tropical Medicine & Hygiene

20. Inadequacy of IgM Antibody Tests for Diagnosis of Rocky Mountain Spotted Fever. Full Text available with Trip Pro

Inadequacy of IgM Antibody Tests for Diagnosis of Rocky Mountain Spotted Fever. Among 13 suspected Rocky Mountain spotted fever (RMSF) cases identified through an enhanced surveillance program in Tennessee, antibodies to Rickettsia rickettsii were detected in 10 (77%) patients using a standard indirect immunofluorescent antibody (IFA) assay. Immunoglobulin M (IgM) antibodies were observed for 6 of 13 patients (46%) without a corresponding development of IgG, and for 3 of 10 patients (30 (...) %) at least 1 year post-onset. However, recent infection with a spotted fever group rickettsiae could not be confirmed for any patient, based on a lack of rising antibody titers in properly timed acute and convalescent serologic specimens, and negative findings by polymerase chain reaction testing. Case definitions used in national surveillance programs lack specificity and may capture cases that do not represent current rickettsial infections. Use of IgM antibodies should be reconsidered as a basis

2014 American Journal of Tropical Medicine & Hygiene

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>