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61. Failure of angiographic management in cases of post renal intervention bleed: Risk factors and management approach. (PubMed)

Failure of angiographic management in cases of post renal intervention bleed: Risk factors and management approach. To evaluate the factors predicting the risk for failed angiographic management (AM), we retrospectively studied cases of digital subtraction angiography (DSA) and superselective angiography (SSA) to control severe/delayed bleeding following renal interventions, which may otherwise be life threatening and often require nephrectomy.We have retrospectively evaluated the data of 154 (...) needed inotropes (P = .008) were found to predict risk for failure. On multivariate analysis, multiple bleeding site >2 (P = .003, odds ratio 5.23, 95% confidence interval = 1.3-22.5) and patients on inotropes (P = .02, odds ratio 2.56, 95% confidence interval = 2.15-4.75) were found to independently predict the failure.Patients with multiple bleeding lesions and who are on inotropic (leading to intrarenal vasoconstriction) are at high risk for failure of AM. Most of them can be successfully managed

2018 Urology

62. Do patients actually do what we ask: patient fidelity and persistence to the Targets and Self-Management for the Control of Blood Pressure in Stroke and at Risk Groups blood pressure self-management intervention. (PubMed)

Do patients actually do what we ask: patient fidelity and persistence to the Targets and Self-Management for the Control of Blood Pressure in Stroke and at Risk Groups blood pressure self-management intervention. Self-management of hypertension can reduce and control blood pressure (BP) compared with clinic monitoring. However, self-management relies on patients following an algorithm, which may be variably adhered to. This study reports fidelity of high-risk patients to the self-management (...) patients were randomized to self-management and 225 (82%) completed the required training sessions. Of these, 166 (74%) completed self-management. A total of 11385 (89.6%) submitted readings were accurate compared with corresponding downloaded monitor readings. Mean error rate was 5.2% per patient, which increased with age but not comorbidities. Patients made 475 of 683 (69.5%) algorithm-recommended medication changes, equating to nearly three medication changes per patient. Mean SBP for patients who

2018 Journal of Hypertension Controlled trial quality: uncertain

63. Bovine Tuberculosis Management in Northwest Minnesota and Implications of the Risk Information Seeking and Processing (RISP) Model for Wildlife Disease Management (PubMed)

Bovine Tuberculosis Management in Northwest Minnesota and Implications of the Risk Information Seeking and Processing (RISP) Model for Wildlife Disease Management Bovine tuberculosis (bTB) is an infectious, zoonotic disease caused by Mycobacterium bovis that can spread between domestic and wild animals, as well as to humans. The disease is characterized by the progressive development of lesions that compromise the victim's lungs and lymph system. The disease was first identified in northwest (...) Minnesota in both cattle and white-tailed deer (Odocoileus virginianus) in 2005. Due to its risks to human and animal health, bTB has numerous implications related to population management, policy outcomes, stakeholder relations, and economic impacts. When dealing with complicated risks, like bTB, individuals often seek out and process information as a method to learn about, and cope, with the risk. We developed a questionnaire that adapted components of the Risk Information Seeking and Processing (RISP

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2018 Frontiers in veterinary science

64. Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018. (PubMed)

Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018. The American Diabetes Association (ADA) annually updates its Standards of Medical Care in Diabetes to provide clinicians, patients, researchers, payers, and other interested parties with evidence-based recommendations for the diagnosis and management of patients with diabetes.For the 2018 standards, the ADA Professional Practice Committee searched MEDLINE through (...) to cardiovascular disease and risk management in nonpregnant adults with diabetes. Recommendations address diagnosis and treatment of cardiovascular risk factors (hypertension and dyslipidemia), aspirin use, screening for and treatment of coronary heart disease, and lifestyle interventions.

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2018 Annals of Internal Medicine

65. Use of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015 (PubMed)

Use of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015 29800017 2018 07 10 2018 12 02 1538-3598 319 21 2018 06 05 JAMA JAMA Use of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015. 2231-2233 10.1001/jama.2018.5616 Loeb Stacy S Manhattan Veterans Affairs Medical Center, New York, New York. Byrne Nataliya N Department of Urology, New York University (...) Conservative Treatment statistics & numerical data trends Delivery of Health Care, Integrated Humans Logistic Models Male Middle Aged Multivariate Analysis Prostate-Specific Antigen blood Prostatic Neoplasms therapy Risk Factors United States United States Department of Veterans Affairs Veterans Watchful Waiting 2018 5 26 6 0 2018 7 11 6 0 2018 5 26 6 0 ppublish 29800017 2681802 10.1001/jama.2018.5616 PMC6134433 JAMA Oncol. 2017 Oct 1;3(10):1393-1398 27768168 BJU Int. 2017 Jul;120(1):32-39 27611479 J Clin

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2018 JAMA

66. Relationship Between Physiological and Perceived Fall Risk in People With Multiple Sclerosis: Implications for Assessment and Management

Relationship Between Physiological and Perceived Fall Risk in People With Multiple Sclerosis: Implications for Assessment and Management This study evaluated the relationship between physiological and perceived fall risk in people with multiple sclerosis (MS).Secondary analysis of data from prospective cohort studies undertaken in Australia, the United Kingdom, and the United States.Community.Ambulatory people with MS (N=416) (age 51.5±12.0 years; 73% female; 62% relapsing-remitting MS; 13.7 (...) ±9.9 years disease duration).Not applicable.All participants completed measures of physiological (Physiological Profile Assessment [PPA]) and perceived (Falls Efficacy Scale-international [FESi]) fall risk and prospectively recorded falls for 3 months.155 (37%) of the participants were recurrent fallers (≥2 falls). Mean PPA and FESi scores were high (PPA 2.14±1.87, FESi 34.27±11.18). The PPA and the FESi independently predicted faller classification in logistic regression, which indicated

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2018 EvidenceUpdates

67. Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. (PubMed)

Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. The perinatal and maternal consequences of induction of labor at 39 weeks among low-risk nulliparous women are uncertain.In this multicenter trial, we randomly assigned low-risk nulliparous women who were at 38 weeks 0 days to 38 weeks 6 days of gestation to labor induction at 39 weeks 0 days to 39 weeks 4 days or to expectant management. The primary outcome was a composite of perinatal death or severe neonatal (...) complications; the principal secondary outcome was cesarean delivery.A total of 3062 women were assigned to labor induction, and 3044 were assigned to expectant management. The primary outcome occurred in 4.3% of neonates in the induction group and in 5.4% in the expectant-management group (relative risk, 0.80; 95% confidence interval [CI], 0.64 to 1.00). The frequency of cesarean delivery was significantly lower in the induction group than in the expectant-management group (18.6% vs. 22.2%; relative risk

2018 NEJM Controlled trial quality: predicted high

68. Impact of Primary Care Intensive Management on High-Risk Veterans' Costs and Utilization: A Randomized Quality Improvement Trial. (PubMed)

Impact of Primary Care Intensive Management on High-Risk Veterans' Costs and Utilization: A Randomized Quality Improvement Trial. Primary care models that offer comprehensive, accessible care to all patients may provide insufficient resources to meet the needs of patients with complex conditions who have the greatest risk for hospitalization.To assess whether augmenting usual primary care with team-based intensive management lowers utilization and costs for high-risk patients.Randomized quality (...) improvement trial. (ClinicalTrials.gov: NCT03100526).5 U.S. Department of Veterans Affairs (VA) medical centers.Primary care patients at high risk for hospitalization who had a recent acute care episode.Locally tailored intensive management programs providing care coordination, goals assessment, health coaching, medication reconciliation, and home visits through an interdisciplinary team, including a physician or nurse practitioner, a nurse, and psychosocial experts.Utilization and costs (including

2018 Annals of Internal Medicine Controlled trial quality: uncertain

69. Implications of Image-Defined Risk Factors and Primary Site Response on Local Control and Radiation Treatment Delivery in the Management of High Risk Neuroblastoma: Is there a Role for De-escalation of Adjuvant Primary Site Radiotherapy? (PubMed)

Implications of Image-Defined Risk Factors and Primary Site Response on Local Control and Radiation Treatment Delivery in the Management of High Risk Neuroblastoma: Is there a Role for De-escalation of Adjuvant Primary Site Radiotherapy? The predictive value of Image-Defined Risk Factors (IDRFs) developed by the International Neuroblastoma Risk Group Task Force as it relates to primary-site management is undefined and may aid patient selection for de-escalation of adjuvant radiation therapy (...) to the primary site in high-risk neuroblastoma.Patients (N = 76) with high-risk neuroblastoma treated on prospective trials at our institution from 1997 to 2014 were eligible for inclusion. IDRFs were defined based on pretherapy imaging. Overall survival, progression-free survival, and locoregional failure-free survival (LRFFS) were described using the Kaplan-Meier estimator and tested across strata by using the log-rank test.Twenty of 76 patients (26%) experienced local (n = 6), regional (n = 6

2018 Biology and Physics

70. Human Reproductive Cell Cryopreservation, Storage, Handling, and Transport: Risks and Risk Management. (PubMed)

Human Reproductive Cell Cryopreservation, Storage, Handling, and Transport: Risks and Risk Management. Millions of human oocytes and embryos are stored in thousands of locations across the globe. This inventory continues to grow as cryopreservation becomes more successful and more widely applied. The results of studies assessing pregnancy and neonatal outcomes following frozen embryo transfer (FET) have been encouraging, showing lower incidences of small for gestational age neonates and preterm (...) tissues, the burden of embryos they no longer wish to use and failing to meet their contractual obligations. Studies are urgently needed to explore and understand all dimensions of cryostorage to help ART clinics develop effective strategies to manage associated risks. The future of cryostorage, as for many other areas of ART and medicine, is automation.Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

2018 Seminars in Reproductive Medicine

71. Correction to: Effect of a Computer-Guided, Quality Improvement Program for Cardiovascular Disease Risk Management in Primary Health Care: The Treatment of Cardiovascular Risk Using Electronic Decision Support Cluster-Randomized Trial. (PubMed)

Correction to: Effect of a Computer-Guided, Quality Improvement Program for Cardiovascular Disease Risk Management in Primary Health Care: The Treatment of Cardiovascular Risk Using Electronic Decision Support Cluster-Randomized Trial. 30354554 2018 10 25 1941-7705 11 9 2018 Sep Circulation. Cardiovascular quality and outcomes Circ Cardiovasc Qual Outcomes Correction to: Effect of a Computer-Guided, Quality Improvement Program for Cardiovascular Disease Risk Management in Primary Health Care (...) : The Treatment of Cardiovascular Risk Using Electronic Decision Support Cluster-Randomized Trial. e000049 10.1161/HCQ.0000000000000049 eng Journal Article Published Erratum United States Circ Cardiovasc Qual Outcomes 101489148 1941-7713 Circ Cardiovasc Qual Outcomes. 2015 Jan;8(1):87-95 25587090 2018 10 26 6 0 2018 10 26 6 0 2018 10 26 6 0 ppublish 30354554 10.1161/HCQ.0000000000000049

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2018 Circulation. Cardiovascular quality and outcomes Controlled trial quality: uncertain

72. The melanoma genomics managing your risk study: A protocol for a randomized controlled trial evaluating the impact of personal genomic risk information on skin cancer prevention behaviors. (PubMed)

The melanoma genomics managing your risk study: A protocol for a randomized controlled trial evaluating the impact of personal genomic risk information on skin cancer prevention behaviors. Reducing ultraviolet radiation (UV) exposure and improving early detection may reduce melanoma incidence, mortality and health system costs. This study aims to evaluate the efficacy and cost-effectiveness of providing information on personal genomic risk of melanoma in reducing UV exposure at 12 months (...) , according to low and high traditional risk.In this randomized controlled trial, participants (target sample = 892) will be recruited from the general population, and randomized (1:1 ratio, intervention versus control). Intervention arm participants provide a saliva sample, receive personalized melanoma genomic risk information, a genetic counselor phone call, and an educational booklet on melanoma prevention. Control arm participants receive only the educational booklet. Eligible participants are aged

2018 Contemporary clinical trials Controlled trial quality: predicted high

73. Risk factors and nursing strategies to manage choking in adults with mental illness: a systematic review protocol. (PubMed)

Risk factors and nursing strategies to manage choking in adults with mental illness: a systematic review protocol. The review objectives are:Specifically, this review seeks to answer the following questions.

2017 JBI database of systematic reviews and implementation reports

74. BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment

BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment Journal of Psychopharmacology 1 –32 © The Author(s) 2016 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0269881116645254 jop.sagepub.com BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment Stephen J Cooper 1,3 (...) briefly as these are similar to those recommended for the general population. The management of impaired fasting glycaemia and impaired glucose tolerance (‘pre-diabetes’), diabetes and other cardiovascular risks, such as dyslipidaemia, are also reviewed with respect to other currently available guidelines. These guidelines were compiled following a consensus meeting of experts involved in various aspects of these problems. They reviewed key areas of evidence and their clinical implications. Wider

2016 British Association for Psychopharmacology

75. A Data Model for Teleconsultation in Managing High-Risk Pregnancies: Design and Preliminary Evaluation (PubMed)

A Data Model for Teleconsultation in Managing High-Risk Pregnancies: Design and Preliminary Evaluation Teleconsultation is a guarantor for virtual supervision of clinical professors on clinical decisions made by medical residents in teaching hospitals. Type, format, volume, and quality of exchanged information have a great influence on the quality of remote clinical decisions or tele-decisions. Thus, it is necessary to develop a reliable and standard model for these clinical relationships.The (...) goal of this study was to design and evaluate a data model for teleconsultation in the management of high-risk pregnancies.This study was implemented in three phases. In the first phase, a systematic review, a qualitative study, and a Delphi approach were done in selected teaching hospitals. Systematic extraction and localization of diagnostic items to develop the tele-decision clinical archetypes were performed as the second phase. Finally, the developed model was evaluated using predefined

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2017 JMIR medical informatics

76. Management of Plasmodium vivax risk and illness in travelers (PubMed)

Management of Plasmodium vivax risk and illness in travelers Malaria poses an exceptionally complex problem for providers of travel medicine services. Perceived high risk of exposure during travel typically prompts prescribing protective antimalarial drugs. Suppressive chemoprophylactic agents have dominated strategy for that practice for over 70 years. This broad class of therapeutic agents kills parasites after they emerge from the liver and attempt development in red blood cells

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2017 Tropical diseases, travel medicine and vaccines

77. Low back pain in older adults: risk factors, management options and future directions (PubMed)

Low back pain in older adults: risk factors, management options and future directions Low back pain (LBP) is one of the major disabling health conditions among older adults aged 60 years or older. While most causes of LBP among older adults are non-specific and self-limiting, seniors are prone to develop certain LBP pathologies and/or chronic LBP given their age-related physical and psychosocial changes. Unfortunately, no review has previously summarized/discussed various factors that may (...) affect the effective LBP management among older adults. Accordingly, the objectives of the current narrative review were to comprehensively summarize common causes and risk factors (modifiable and non-modifiable) of developing severe/chronic LBP in older adults, to highlight specific issues in assessing and treating seniors with LBP, and to discuss future research directions. Existing evidence suggests that prevalence rates of severe and chronic LBP increase with older age. As compared to working-age

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2017 Scoliosis and spinal disorders

78. GLOBAL RISK ASSESSMENT TO GUIDE BLOOD PRESSURE MANAGEMENT IN CARDIOVASCULAR DISEASE PREVENTION (PubMed)

GLOBAL RISK ASSESSMENT TO GUIDE BLOOD PRESSURE MANAGEMENT IN CARDIOVASCULAR DISEASE PREVENTION 28115516 2018 01 29 2019 01 09 1524-4563 69 3 2017 03 Hypertension (Dallas, Tex. : 1979) Hypertension Global Risk Assessment to Guide Blood Pressure Management in Cardiovascular Disease Prevention. e2-e9 10.1161/HYPERTENSIONAHA.116.08249 Karmali Kunal N KN From the Department of Medicine, Division of Cardiology (K.N.K, D.M.L.-J.), Center for Primary Care Innovation, Institute of Public Health (...) United States Journal Article Research Support, N.I.H., Extramural 2017 01 23 United States Hypertension 7906255 0194-911X 0 Antihypertensive Agents IM Antihypertensive Agents pharmacology therapeutic use Blood Pressure drug effects physiology Blood Pressure Monitoring, Ambulatory Cardiovascular Diseases physiopathology prevention & control Humans Hypertension drug therapy physiopathology Practice Guidelines as Topic Risk Assessment 2016 11 17 2016 11 28 2016 12 28 2017 1 25 6 0 2018 1 30 6 0 2017 1

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2017 Hypertension (Dallas, Tex. : 1979)

79. Current Biochemical Monitoring and Risk Management of Immunosuppressive Therapy after Transplantation (PubMed)

Current Biochemical Monitoring and Risk Management of Immunosuppressive Therapy after Transplantation Immunosuppressive drugs play a crucial role in the inhibition of immune reaction and prevention of graft rejection aswell as in the pharmacotherapy of autoimmune disorders. Effective immunosuppression should provide an adequate safety profile and improve treatment outcomes and the patients' quality of life. High-risk transplant recipients may be identified, but a definitive prediction model has (...) still not been recognized. Therapeutic drug monitoring (TDM) for immunosuppressive drugs is an essential, but at the same time insufficient tool due to low predictability of drug exposition and marked pharmacokinetic variability. Parallel therapeutic, biochemical and clinical monitoring may successfully optimize and individualize therapy for transplanted recipients, providing optimal medical outcomes. Modern pharmacotherapy management should include new biomarkers with better sensitivity

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2017 Journal of medical biochemistry

80. A six stage operational framework for individualising injury risk management in sport (PubMed)

A six stage operational framework for individualising injury risk management in sport Managing injury risk is important for maximising athlete availability and performance. Although athletes are inherently predisposed to musculoskeletal injuries by participating in sports, etiology models have illustrated how susceptibility is influenced by repeat interactions between the athlete (i.e. intrinsic factors) and environmental stimuli (i.e. extrinsic factors). Such models also reveal (...) that the likelihood of an injury emerging across time is related to the interconnectedness of multiple factors cumulating in a pattern of either positive (i.e. increased fitness) or negative adaptation (i.e. injury).The process of repeatedly exposing athletes to workloads in order to promote positive adaptations whilst minimising injury risk can be difficult to manage. Etiology models have highlighted that preventing injuries in sport, as opposed to reducing injury risk, is likely impossible given our inability

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2017 Injury epidemiology

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