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Rheumatologic Conditions in the Elderly

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1. Medication adherence and persistence over time with self-administered TNF-alpha inhibitors among young adult, middle-aged, and older patients with rheumatologic conditions. (Abstract)

Medication adherence and persistence over time with self-administered TNF-alpha inhibitors among young adult, middle-aged, and older patients with rheumatologic conditions. Self-injectable TNF inhibitors are increasingly used early in the chronic treatment of moderate to severe rheumatologic conditions. We estimated medication adherence/persistence over time following initiation in young adult and older adult patients with rheumatoid arthritis, ankylosing spondylitis or psoriatic arthritis.We (...) equation models were used to calculate odds ratios (OR) and robust 95% confidence intervals (CI) for associations between patient characteristics and repeated adherence/persistence measures over time.Among 53,477 new users, 14% were young adults (18-34 years), 49% middle-aged (35-54 years), and 37% older adults (55+ years). Overall, 37% of patients were adherent and 83% were persistent in the first year of therapy. The lowest adherence (17%) and persistence (70%) were observed among young adult

2017 Seminars in arthritis and rheumatism

2. AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol

Assistants (AAPA), Association of Black Cardiologists (ABC), American College of Preventive Medicine (ACPM), American Diabetes Association (ADA), American Geriatrics Society (AGS), American Pharmacists Association (APhA), American Society for Preventive Cardiology (ASPC), National Lipid Association (NLA), and Preventive Cardiovascular Nurses Association (PCNA). Appendix 1 of the present document lists writing committee members’ relevant relationships with industry and other entities. For the purposes (...) recommendations are summarized in Online Data Supplement 1. COR LOE Recommendations I B-NR 1. In adults who are 20 years of age or older and not on lipid-lowering therapy, measurement of either a fasting or a nonfasting plasma lipid profile is effective in estimating ASCVD risk and documenting baseline LDL-C (S2.2-1– S2.2-6). I B-NR 2. In adults who are 20 years of age or older and in whom an initial nonfasting lipid profile reveals a triglycerides level of 400 mg/dL (=4.5 mmol/L) or higher, a repeat lipid

2018 American College of Cardiology

3. Acutely Limping Child Up To Age 5

To Age 5 The ACR Committee on Appropriateness Criteria and its expert panels have developed criteria for determining appropriate imaging examinations for diagnosis and treatment of specified medical condition(s). These criteria are intended to guide radiologists, radiation oncologists and referring physicians in making decisions regarding radiologic imaging and treatment. Generally, the complexity and severity of a patient’s clinical condition should dictate the selection of appropriate imaging (...) Acutely Limping Child Up To Age 5 Revised 2018 ACR Appropriateness Criteria ® 1 Acutely Limping Child Up To Age 5 American College of Radiology ACR Appropriateness Criteria ® Acutely Limping Child Up To Age 5 Variant 1: Child up to age 5. Acute limp. Nonlocalized symptoms. No concern for infection. Initial imaging. Procedure Appropriateness Category Relative Radiation Level Radiography tibia/fibula Usually Appropriate ? Radiography femur May Be Appropriate ?? Radiography foot May Be Appropriate

2018 American College of Radiology

4. Gaps in Aging Research as it Applies to Rheumatologic Clinical Care. Full Text available with Trip Pro

Gaps in Aging Research as it Applies to Rheumatologic Clinical Care. The incidence and prevalence of rheumatologic conditions are increasing and the rheumatology workforce must be aware of aging-specific issues. This article reviews specific barriers to understanding the biology of aging and aging-related mechanisms that may underlie development of rheumatologic diseases in older adults. It summarizes gaps in the assessment, outcomes measurement, and treatment of these diseases in this unique (...) population. It also highlights potential solutions to these barriers and suggests possible ways to bridge the gap, from a research and education standpoint, so that clinicians can be better prepared to effectively manage older adults with rheumatologic conditions.Published by Elsevier Inc.

2017 Clinics in geriatric medicine

5. Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia

studies used multidomain interventions, and potentially none have explored the possibility of cumulative or synergistic effects. Timing and measurement choices affect cognitive decline prevention studies. Researchers can recruit participants at any point along the cognitive continuum. Various proposed strategies target young and middle-aged adults with no evidence of cognitive decline, older adults worried about age-related changes, people with documented MCI, and those with major neurocognitive (...) , costly medical conditions, and new health care technologies and strategies. The National Institute on Aging of the National Institutes of Health requested this report from the AHRQ Evidence-based Practice Center (EPC) Program. The report was presented October 25, 2016, at the National Academies of Sciences, Engineering, and Medicine public meeting Preventing Dementia and Cognitive Impairment: A Workshop. The reports and assessments provide organizations with comprehensive, evidence-based information

2017 Effective Health Care Program (AHRQ)

6. Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia

studies used multidomain interventions, and potentially none have explored the possibility of cumulative or synergistic effects. Timing and measurement choices affect cognitive decline prevention studies. Researchers can recruit participants at any point along the cognitive continuum. Various proposed strategies target young and middle-aged adults with no evidence of cognitive decline, older adults worried about age-related changes, people with documented MCI, and those with major neurocognitive (...) , costly medical conditions, and new health care technologies and strategies. The National Institute on Aging of the National Institutes of Health requested this report from the AHRQ Evidence-based Practice Center (EPC) Program. The report was presented October 25, 2016, at the National Academies of Sciences, Engineering, and Medicine public meeting Preventing Dementia and Cognitive Impairment: A Workshop. The reports and assessments provide organizations with comprehensive, evidence-based information

2017 Effective Health Care Program (AHRQ)

7. Analysis of Changes in Medication Prescriptions After Hospitalization for 4 Disciplines: Gerontology, Diabetology, Cardiology and Rheumatology: Medical, Pharmaceutical and Economic Aspects

information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Probability Sample Study Population Patients must be hospitalized in one of the services of a university hospital, in the following 4 disciplines: diabetology, geriatrics, cardiology and rheumatology Criteria inclusion criteria Patient social insured Patient belonging to the general social security scheme Patient followed (...) Analysis of Changes in Medication Prescriptions After Hospitalization for 4 Disciplines: Gerontology, Diabetology, Cardiology and Rheumatology: Medical, Pharmaceutical and Economic Aspects Analysis of Changes in Medication Prescriptions After Hospitalization for 4 Disciplines: Gerontology, Diabetology, Cardiology and Rheumatology: Medical, Pharmaceutical and Economic Aspects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting

2017 Clinical Trials

8. Rheumatologic Conditions in the Elderly

Rheumatologic Conditions in the Elderly Rheumatologic Conditions in the Elderly Aka: Rheumatologic Conditions in the Elderly II. Epidemiology Overall health declines with chronic hip or III. Causes: Common Rheumatologic Conditions seen in over age 75 (60%) (39%) and other crystalline (15%) (14%) (13%) (4%) References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Rheumatologic Conditions in the Elderly." Click on the image (or right (...) Rheumatologic Conditions in the Elderly Rheumatologic Conditions in the Elderly Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4

2018 FP Notebook

9. Prescribing for rheumatological conditions in pregnancy and breastfeeding - Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Full Text available with Trip Pro

Prescribing for rheumatological conditions in pregnancy and breastfeeding - Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs (...) and corticosteroids | Rheumatology | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input Article Navigation Close mobile search navigation Article navigation September 2016 Article Contents Article Navigation BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids Julia Flint 1 Centre for Rheumatology Research, UCL Division of Medicine

2016 British Society for Rheumatology

10. Cost-Utility Analysis of High Molecular Weight Hyaluronic Acid for Knee Osteoarthritis in Everyday Clinical Care in Patients at a Working Age: An Economic Evaluation of a Randomized Clinical Trial Full Text available with Trip Pro

resulted in an incremental cost-effectiveness ratio of €9,100/QALY from a societal perspective and €8,700/QALY from a health care perspective. When the maximum willingness to pay for conditions similar to knee OA is considered, the probability on cost-effectiveness is 64% and 86%, respectively.Intraarticular HMW-HA added to usual care for knee OA is probably cost-effective in the treatment of knee OA.© 2017, American College of Rheumatology. (...) Cost-Utility Analysis of High Molecular Weight Hyaluronic Acid for Knee Osteoarthritis in Everyday Clinical Care in Patients at a Working Age: An Economic Evaluation of a Randomized Clinical Trial Knee osteoarthritis (OA) is associated with high medical costs and especially with high productivity costs, in particular in patients in their working years. High molecular weight (HMW) hyaluronic acid (HA) is an alternative treatment for nonsteroidal antiinflammatory drugs, which are known

2018 EvidenceUpdates

11. American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

people worldwide (1–5), and is a leading cause of disability among older adults. The knees, hips, and hands are the most commonly affected appendicular joints. OA is characterized by pathology involving the whole joint, includ- ing cartilage degradation, bone remodeling, osteophyte forma- tion, and synovial inflammation, leading to pain, stiffness, swelling, and loss of normal joint function. As OA spans decades of a patient’s life, patients with OA are likely to be treated with a number of different (...) American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee 1 Arthritis Care & Research Vol. 0, No. 0, Month 2020, pp 1–14 DOI 10.1002/acr.24131 © 2020, American College of Rheumatology 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee Sharon L. Kolasinski, 1 Tuhina Neogi, 2 Marc C. Hochberg, 3 Carol Oatis, 4 Gordon Guyatt, 5 Joel Block, 6 Leigh

2020 American College of Rheumatology

12. Canadian Rheumatology Association recommendations for the assessment and monitoring of systemic lupus erythematosus

are or have been Conditional recommendation, low-quality screening sexually active, regardless of sexual orientation, we suggest annual evidence cervical cancer screening rather than screening every 3 years, at least up to the age of 69. of Rheumatology The Journal on March 26, 2019 - Published by www.jrheum.org Downloaded from The recommendation considers resource requirements to be negligible but recognizes variability depending on what score is used. Damage (Supplementary Data 3, Damage, available (...) the GRADE method for the monitoring of SLE. Existing evidence is largely of low to moderate quality, resulting in more conditional than strong recommendations. Additional rigorous studies and special attention to pediatric SLE popula- tions and patient preferences are needed. (J Rheumatol First Release September 1 2018; doi:10.3899/ jrheum.171459) Key Indexing Terms: SYSTEMIC LUPUS ERYTHEMATOSUS GRADE RECOMMENDATIONS MONITORING ASSESSMENT COMORBIDITIES From the Division of Rheumatology, Department

2018 CPG Infobase

13. Assessment of the Effect of Spa Treatment on Rheumatological Conditions

research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patient presenting an indication for rheumatological spa treatment Patient with osteoarthritis or other rheumatic disease, located on the lower limbs with or without chronic lower back pain. Functional impairment with reduced mobility (...) Assessment of the Effect of Spa Treatment on Rheumatological Conditions Assessment of the Effect of Spa Treatment on Rheumatological Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Assessment

2018 Clinical Trials

14. An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Osteoarthritis of the Knee

of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 35 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria (...) : Patients must be diagnosed as having primary (idiopathic) femoro-tibial osteoarthritis (OA) of the knee as defined by a modified version of the American College of Rheumatology Criteria (modified clinical and laboratory criteria) for at least 6 months. Kellgren-Lawrence (KL) score of grade 1 to 4 inclusive based on a standardized, semi-fixed, weight-bearing radiograph of the knee. Adults of age ≥ 35 years Body Mass Index less than or equal to an upper limit of 35 kg/m2 Patients who are able to commit

2017 Clinical Trials

15. American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis

American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis 717 Arthritis Care & Research Vol. 71, No. 6, June 2019, pp 717–734 DOI 10.1002/acr.23870 © 2019, American College of Rheumatology SPECIAL ARTICLE 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non (...) for these conditions. GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to rate the quality of evidence. A group consensus process was conducted among the Voting Panel to generate the final recommendations and grade their strength. A Parent and Patient Panel used a similar consensus approach to provide patient/caregiver preferences for key questions. Results. Thirty- nine recommendations were developed (8 strong and 31 conditional). The quality of supporting evidence

2019 American College of Rheumatology

16. Age Influence on Cortical Bone Measured by Ultrasound

Information provided by (Responsible Party): Assistance Publique - Hôpitaux de Paris Study Details Study Description Go to Brief Summary: The study of this study is to evaluate the age influence on cortical bone strength properties by two methods:HR-pQCT (HighResolution-peripheral quantitativeComputedTomography) and ultrasound. The main objective consists in the evaluation of the age influence on cortical thickness at 1/3 distal radius measured by US. Condition or disease Intervention/treatment Cortical (...) the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling

2018 Clinical Trials

17. Device Evaluating the Muscular Functional Age

Technologie de Compiegne Sorbonne Université Information provided by (Responsible Party): Assistance Publique - Hôpitaux de Paris Study Details Study Description Go to Brief Summary: The CHRONOS project aims to provide a device to detect earlier the motor decline, by developing a precise quantitative device measuring "Motor Functional Age" (MFA) of young, middle-aged and old people, thus preventing future functional motor loss for healthy aging. The MFA might be different from the Chronological Age (CA (...) evaluation. These data will provide with a built-in clinical database of subjects from different age categories (25-75 years old). Condition or disease Intervention/treatment Phase Healthy Volunteers Skeletal Muscle Device: High definition surface electromyography combined with accelerometer Not Applicable Detailed Description: Background: Aging is accompanied by sarcopenia, defined by a loss in muscle mass (starting from the age of 25) and strength/function, leading to a decline in mobility

2018 Clinical Trials

18. Cohort study: Long-term aspirin use and neovascular age-related macular degeneration: association or causation?

-related macular degeneration: association or causation? William G Christen Statistics from Altmetric.com Commentary on: Liew G , Mitchell P , Wong TY , et al . The association of aspirin use with age-related macular degeneration . Context Aspirin is used by many for temporary pain relief, rheumatological conditions and where indicated, cardioprotection. However, recent findings from observational studies have raised the possibility that regular aspirin use may also increase the risk of some forms (...) Cohort study: Long-term aspirin use and neovascular age-related macular degeneration: association or causation? Long-term aspirin use and neovascular age-related macular degeneration: association or causation? | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password

2014 Evidence-Based Medicine

19. The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis Full Text available with Trip Pro

* Monitoring Monitor* Test* Connective tissue disease Drug induced vasculitis Drug AND induced AND lupus Drug induced lupus Haematological disorders Anaemia Neutropenia Pancytopenia Aplastic anaemia Lymphopeni* Thrombocytopeni* Psoriasis Drug induced psoriasis Peri-operative period Postoperative infection Surgery + infection Other terms Elderly Geriatric* Care of the elderly Mortality Safety Topic Search terms used in addition to either: ‘Rheumatoid + arthritis’, ‘Ankylosing spondylitis’, ‘Seronegative (...) induced vasculitis Drug AND induced AND lupus Drug induced lupus Haematological disorders Anaemia Neutropenia Pancytopenia Aplastic anaemia Lymphopeni* Thrombocytopeni* Psoriasis Drug induced psoriasis Peri-operative period Postoperative infection Surgery + infection Other terms Elderly Geriatric* Care of the elderly Mortality Safety Table 3 Search terms used for literature review Topic Search terms used in addition to either: ‘Rheumatoid + arthritis’, ‘Ankylosing spondylitis’, ‘Seronegative

2018 British Society for Rheumatology

20. Validation of the Fitbit Charge 2 compared to the ActiGraph GT3X+ in older adults with knee osteoarthritis in free-living conditions. Full Text available with Trip Pro

Validation of the Fitbit Charge 2 compared to the ActiGraph GT3X+ in older adults with knee osteoarthritis in free-living conditions. To evaluate physical activity (PA) and sedentary time in subjects with knee osteoarthritis (OA) measured by the Fitbit Charge 2 (Fitbit) and a wrist-worn ActiGraph GT3X+ (AGW) compared to the hip-worn ActiGraph (AGH).We recruited a cohort of subjects with knee OA from rheumatology clinics. Subjects wore the AGH for four weeks, AGW for two weeks, and Fitbit (...) subjects (67% female, mean age 68 years). Relative to AGH, Fitbit, on average, overestimated steps by 39% and sedentary time by 37% and underestimated MVPA by 5 minutes. Relative to AGH, AGW overestimated steps 116%, underestimated sedentary time by 66%, and captured 281 additional MVPA minutes. The step-based wear time Fitbit algorithm captured 14% less wear time than the HR-based algorithm.Fitbit overestimates steps and underestimates MVPA in knee OA subjects. Cut-offs validated for AGW should

2019 PLoS ONE

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