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136321. Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Full Text available with Trip Pro

Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. To provide evidence-based recommendations on the treatment of nervous system Lyme disease and post-Lyme syndrome. Three questions were addressed: 1) Which antimicrobial agents are effective? 2) Are different regimens preferred for different manifestations of nervous system Lyme disease? 3) What duration of therapy is needed (...) ?The authors analyzed published studies (1983-2003) using a structured review process to classify the evidence related to the questions posed.The panel reviewed 353 abstracts which yielded 112 potentially relevant articles that were reviewed, from which 37 articles were identified that were included in the analysis.There are sufficient data to conclude that, in both adults and children, this nervous system infection responds well to penicillin, ceftriaxone, cefotaxime, and doxycycline (Level B

2007 Neurology

136322. Development of an Audio-Tape Review System for Supporting Adherence to an Evidence-Based Treatment. Full Text available with Trip Pro

Development of an Audio-Tape Review System for Supporting Adherence to an Evidence-Based Treatment. In bridging the science to service gap, effective, yet practical, strategies are needed for supporting practitioner implementation of evidence-based treatments. The development and preliminary evaluation of an adherence monitoring system to support clinician fidelity to an evidence-based treatment for substance-abusing adolescents was tested for community-based practitioners. Session tapes were (...) monitored for adherence to a family-based approach to CM (CM/FB) for 27 practitioners during baseline, post-workshop, and follow-up periods. Approximately half of the practitioners were randomized to receive intensive quality assurance following a CM/FB workshop as part of a larger study. Findings supported the clinical feasibility of the developed system as well as the face and content validity, reliability, and concurrent validity. Future directions are discussed in light of these results, including

2008 Professional psychology, research and practice Controlled trial quality: uncertain

136323. Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. (Abstract)

Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. The concept of hypertension as primarily a consequence of altered hemodynamics has changed. Many factors are now implicated in the development of hypertensive vascular disease, and the renin-angiotensin-aldosterone system (RAAS) appears to be one of the most significant. Angiotensin II, the principal effector peptide of the RAAS, has far-reaching effects on vascular structure, growth

2006 Journal of Hypertension

136324. Kaposi sarcoma of the musculoskeletal system: a review of 66 patients. Full Text available with Trip Pro

Kaposi sarcoma of the musculoskeletal system: a review of 66 patients. Kaposi sarcoma (KS) of bone and skeletal muscle is unusual. In this report, the authors review 66 published patients with KS who had involvement of the musculoskeletal system reported from 1925 to 2006. In only 3 patients was acquired immunodeficiency syndrome (AIDS)-related KS identified within skeletal muscle. Osseous KS lesions were more frequent and occurred with African, classic, and AIDS-related KS and occurred rarely

2007 Cancer

136325. Cognitive functions in primary central nervous system lymphoma: literature review and assessment guidelines. Full Text available with Trip Pro

Cognitive functions in primary central nervous system lymphoma: literature review and assessment guidelines. Treatment-related neurotoxicity has been recognized as a significant problem in patients with primary central nervous system lymphoma (PCNSL) as effective treatment has increased survival rates. There is, however, a paucity of research on cognitive functions in this population.In a review of the literature, a total of 17 articles that described cognitive outcome in adult PCNSL patients (...) were identified.The studies that assessed cognitive functions after whole-brain radiotherapy combined with chemotherapy reported cognitive impairment in most patients. Patients treated with chemotherapy alone had either stable or improved cognitive performance in most studies. Methodological problems, however, limited the ability to ascertain the specific contribution of disease and various treatment interventions to cognitive outcome. On the basis of the literature review, a battery of cognitive

2007 Annals of Oncology

136326. Original and reviewed nuclear grading according to the Fuhrman system: a multivariate analysis of 388 patients with conventional renal cell carcinoma. Full Text available with Trip Pro

Original and reviewed nuclear grading according to the Fuhrman system: a multivariate analysis of 388 patients with conventional renal cell carcinoma. The objective of the current study was to evaluate the reproducibility of the Fuhrman nuclear grading system as well as its independent predictive value in a series of patients with conventional renal cell carcinoma (RCC).The authors selected 388 patients who had undergone surgical treatment for conventional RCC between 1986 and 2000. Pathology (...) the original and the reviewed Fuhrman nuclear grading systems were capable of independently predicting disease-specific survival in patients with conventional RCC.The interobserver reproducibility of Fuhrman nuclear grading was moderate. The substantial overlap in survival curves for G1 and G2 tumors provided an opportunity to cluster those categories, and the resulting three-tiered nuclear grading system was an independent predictor of cause-specific survival in patients with conventional RCC. Other

2005 Cancer

136327. Should the Gleason grading system for prostate cancer be modified to account for high-grade tertiary components? A systematic review and meta-analysis. (Abstract)

Should the Gleason grading system for prostate cancer be modified to account for high-grade tertiary components? A systematic review and meta-analysis. The Gleason system for grading prostate cancer assigns a score on the basis of the most prevalent and second most prevalent grade. Several studies have investigated the clinical significance of a tertiary grade in radical prostatectomy samples. A systematic search of the published work identified seven studies that reported the prognostic value (...) and be considered in the interpretation and design of clinical trials. However, all studies assessed for this review were retrospective, potentially affected by selection bias, and based on radical prostatectomy samples or transurethral resections rather than biopsy samples. Therefore, more evidence is needed to warrant the adaptation of the Gleason system to account for the presence of a tertiary grade, especially when scoring prostatic biopsies and applying predictive algorithms.

2007 Lancet Oncology

136328. Propolis and the immune system: a review. (Abstract)

Propolis and the immune system: a review. Propolis has been used empirically for centuries and it was always mentioned as an immunomodulatory agent. In recent years, in vitro and in vivo assays provided new information concerning its mechanisms of action, thus a review dealing with propolis and the immune system became imperative. This review compiles data from our laboratory as well as from other researchers, focusing on its chemical composition and botanical sources, the seasonal effect (...) of academic interest but also of those who use propolis as well. This review opens a new perspective on the investigation of propolis biological properties, mainly with respect to the immune system.

2007 Journal of Ethnopharmacology

136329. Systemic complications after head injury: a clinical review. Full Text available with Trip Pro

Systemic complications after head injury: a clinical review. Non-neurological organ dysfunction is common after traumatic brain injury and is an independent contributor to morbidity and mortality. It represents a risk factor that is potentially amenable to treatment, and early recognition and prompt intervention may improve outcome. This article reviews the current evidence for the mechanisms and treatment of non-neurological organ dysfunction after head injury.

2007 Anaesthesia

136330. Intraoperative awareness in a regional medical system: a review of 3 years' data. (Abstract)

Intraoperative awareness in a regional medical system: a review of 3 years' data. Intraoperative awareness in patients undergoing general anesthesia is an infrequent but well-described adverse outcome. The reported incidence of this phenomenon is between 0.1% and 0.9%.With institutional review board approval, the authors reviewed continuous quality improvement data from 3 yr (2002-2004) at the locations where the physician group provided anesthesia. Board-certified anesthesiologists supervising

2007 Anesthesiology

136331. A proposed classification and scoring system for supraglottic sealing airways: a brief review. Full Text available with Trip Pro

A proposed classification and scoring system for supraglottic sealing airways: a brief review. We provide an approach to evaluating sealing supraglottic airways by using a classification based on a sealing mechanism. Three main sealing mechanisms are identified, thus defining three groups: cuffed perilaryngeal sealers, cuffed pharyngeal sealers, and uncuffed anatomically preshaped sealers. We provide a brief overview of supraglottic airways and present a scoring system that is relevant

2004 Anesthesia and Analgesia

136332. Possible role of gadolinium in nephrogenic systemic fibrosis: report of two cases and review of the literature. (Abstract)

Possible role of gadolinium in nephrogenic systemic fibrosis: report of two cases and review of the literature. Nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathy (NSF/NFD) is a rare fibrosing disorder that occurs in patients with renal failure. It is associated with significant mortality and morbidity. Patients typically present with painful or pruritic indurated plaques involving the limbs and trunk, with sparing of the face. Severity and rapidity of cutaneous progression

2007 Clinical & Experimental Dermatology

136333. The role of mast cells in atopy: what can we learn from canine models? A thorough review of the biology of mast cells in canine and human systems. (Abstract)

The role of mast cells in atopy: what can we learn from canine models? A thorough review of the biology of mast cells in canine and human systems. Mast cell research has largely focused on the role of these cells in the early phase of allergic reactions. However, their involvement may well extend beyond this stage, and even reach across nonallergic conditions. Mast cells from different sources have helped advance our knowledge of their biology. Although in vitro and in vivo research (...) this field. Here we provide a detailed review of the data reported from in vitro and in vivo studies of canine mast cells, and compare them with results obtained in human systems. We also highlight direct evidence of the mast cell contribution to canine atopy. We conclude that the dog offers useful in vitro and in vivo models in which to investigate mast cell behaviour, and that its use should be considered when undertaking studies aimed either at elucidating the role of mast cells in health and disease

2006 British Journal of Dermatology

136334. Systemic contact dermatitis after oral exposure to nickel: a review with a modified meta-analysis. Full Text available with Trip Pro

Systemic contact dermatitis after oral exposure to nickel: a review with a modified meta-analysis. Systemic contact dermatitis can be elicited experimentally in nickel-sensitive individuals by oral nickel exposure. A crucial point interpreting such experiments has been the relevance of nickel exposure from drinking water and diet. The aim of this meta-analysis study on former nickel-exposure investigations was to provide the best possible estimation of threshold values of nickel doses that may (...) cause systemic contact dermatitis in nickel-sensitive patients. 17 relevant investigations were identified, and statistical analyses were performed in a stepwise procedure. 9 studies were included in the final dose-response analysis, which divided the studies into a homogenous middle group of 5 studies and 2 groups of 2 studies with a higher and lower response frequency, respectively, described by logistic dose-response curves shifted in parallel. On the basis of these curves, calculations were made

2006 Contact Dermatitis

136335. Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. (Abstract)

Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. Many computer software developers and vendors claim that their systems can directly improve clinical decisions. As for other health care interventions, such claims should be based on careful trials that assess their effects on clinical performance and, preferably, patient outcomes.To systematically review controlled clinical trials assessing the effects of computer (...) -based clinical decision support systems (CDSSs) on physician performance and patient outcomes.We updated earlier reviews covering 1974 to 1992 by searching the MEDLINE, EMBASE, INSPEC, SCISEARCH, and the Cochrane Library bibliographic databases from 1992 to March 1998. Reference lists and conference proceedings were reviewed and evaluators of CDSSs were contacted.Studies were included if they involved the use of a CDSS in a clinical setting by a health care practitioner and assessed the effects

1998 JAMA

136336. Artificial and bioartificial support systems for acute and acute-on-chronic liver failure: a systematic review. (Abstract)

Artificial and bioartificial support systems for acute and acute-on-chronic liver failure: a systematic review. Artificial and bioartificial support systems may provide a "bridge" for patients with severe liver disease to recovery or transplantation.To evaluate the effect of artificial and bioartificial support systems for acute and acute-on-chronic liver failure.Randomized trials on any support system vs standard medical therapy were included irrespective of publication status or language (...) were extracted and trial quality was assessed independently by 3 reviewers (L.L.K., J.L., B.A-N.). The primary outcome measure was all-cause mortality. Results were combined on the risk ratio (RR) scale. Random-effects models were used. Sources of heterogeneity were explored through meta-regression and stratified meta-analyses.Of the 12 trials included, 10 assessed artificial systems for acute or acute-on-chronic liver failure and 2 assessed bioartificial systems for acute liver failure. Overall

2003 JAMA

136337. How well do physicians use electronic information retrieval systems? A framework for investigation and systematic review. (Abstract)

How well do physicians use electronic information retrieval systems? A framework for investigation and systematic review. Despite the proliferation of electronic information retrieval (IR) systems for physicians, their effectiveness has not been well assessed. The purpose of this review is to provide a conceptual framework and to apply the results of previous studies to this framework.All sources of medical informatics and information science literature, including MEDLINE, along (...) of studies could be done. General conclusions were drawn from data where appropriate. A total of 47 articles were found to include an evaluation component and were used to develop the framework. Of these, 21 articles met the inclusion criteria for 1 or more of the categories in the framework. Most use of IR systems by physicians still occurs with bibliographic rather than full-text databases. Overall use of IR systems occurs just 0.3 to 9 times per physician per month, whereas physicians have 2

1998 JAMA

136338. Implementation and evaluation of workflow based on hospital information system/radiology information system/picture archiving and communications system Full Text available with Trip Pro

Implementation and evaluation of workflow based on hospital information system/radiology information system/picture archiving and communications system The purpose of this presentation is to review and evaluate computerized workflow of selected sites that have integrated systems of the hospital information system (HIS), radiology information system (RIS), and picture archiving and communications system (PACS). We then focus on some essential points of integration of those systems

1999 Journal of Digital Imaging

136339. Review article: drug-induced microscopic colitis - proposal for a scoring system and review of the literature. Full Text available with Trip Pro

Review article: drug-induced microscopic colitis - proposal for a scoring system and review of the literature. The pathophysiology of microscopic colitis is unknown, although it is thought to be because of an abnormal immune reaction to luminal antigens in predisposed hosts. Specific antigens have not been proved, although various infectious triggers and drugs have been proposed. The responsibility of several drugs has been questioned, some with strong clinical and/or histological evidence (...) suggesting causality. The issue of drug-induced microscopic colitis is important because of the burden of this disease. Thus, any case that can be cured by withdrawal of a drug must be identified. In this report, we propose a scoring system for drug-induced microscopic colitis, adapting existing criteria of drug causality, and review the literature using this framework. Based on this review, several drugs are identified with intermediate or high likelihood of inducing microscopic colitis. Finally, we

2005 Alimentary Pharmacology & Therapeutics

136340. Who is reviewing the data review systems of automated external defibrillators? Implications of flawed time lines for clinicians and researchers. (Abstract)

Who is reviewing the data review systems of automated external defibrillators? Implications of flawed time lines for clinicians and researchers. The unintentional print-out by two different software programmes of the same resuscitation-related events stored on a data card of a Laerdal FR2-automated external defibrillator (AED), led to the discovery of flaws in the registration of the time line by one of the commercially available Laerdal software programmes. This observation stresses the need

2007 Resuscitation

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