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125341. Assessing the Need, Use, and Developments in Mental Health/Substance Abuse Care Full Text available with Trip Pro

Assessing the Need, Use, and Developments in Mental Health/Substance Abuse Care This overview presents an introduction to the articles published in this issue of the health care Financing Review, entitled "Mental Health Services and Vulnerable Populations." This article discusses the challenges the mental health and substance abuse (MH/SA) care system is confronted with in terms of equity and efficiency and how the system is responding to these challenges. It further addresses research issues (...) in assessing the need and use of mental health services and summarizes recent activities in the research and evaluation of new delivery and payment systems.

1997 Health Care Financing Review

125342. Apoptosis: Molecular mechanisms, regulation and role in pathogenesis Full Text available with Trip Pro

Apoptosis: Molecular mechanisms, regulation and role in pathogenesis To review the current state of knowledge of apoptosis, with an emphasis on identifying potential and established roles for apoptosis in the pathogenesis of infectious diseases.MEDLINE and the University of British Columbia library system were searched using the search subject, "apoptosis", for the years 1992 to 1996. Further search terms (eg, "pathogenesis") were used to narrow the results. These review articles and reference (...) books were used as the basis for locating original articles on particular studies.Approximately 40 studies were reviewed, with the criterion for selection being the relevance to either the molecular mechanisms behind apoptosis or roles for apoptosis in the pathogenesis of infectious diseases.Relevant information from each study was collated into categories specific to morphological and biochemical characterization, and the regulation and molecular mechanisms of apoptosis and its role

1997 The Canadian Journal of Infectious Diseases

125343. Processes involved in reading imaging studies: Workflow analysis and implications for workstation development Full Text available with Trip Pro

. We studied work flow using a bottleneck analysis. Twenty-four of a total of 54 cases (44%) involved comparing the images with those of prior scans. Forty-seven of 54 scans (87%) were viewed using windows other than soft tissue, or compared with precontrast scans. In 46 cases (85%), the interpretation stopped to return to a previous level for review. Measurement of lesions was performed in 24 of 54 (44%) cases, and in 15 (63%) of these cases, measurements were taken of lesions on old studies (...) for comparison. Interpretation was interrupted in 14 of 54 cases (26%) by referring clinicians desiring consultation. The work flow analysis showed film folder retrieval by the film room to be the bottleneck for interpretation by film. For picture archiving and communication system (PACS) reading, the CT examination itself proved to be the bottleneck. We conclude that workstations for CT interpretation should facilitate movement within scans, comparison with prior examinations, and measuring lesions

1997 Journal of Digital Imaging

125344. Susceptibility loci for lupus: a guiding light from murine models? Full Text available with Trip Pro

Susceptibility loci for lupus: a guiding light from murine models? 9045853 1997 03 20 2018 11 13 0021-9738 99 4 1997 Feb 15 The Journal of clinical investigation J. Clin. Invest. Susceptibility loci for lupus: a guiding light from murine models? 557-8 Kotzin B L BL eng Editorial Review United States J Clin Invest 7802877 0021-9738 AIM IM Animals Disease Models, Animal Disease Susceptibility Genetic Linkage Humans Lupus Erythematosus, Systemic etiology genetics Mice 12 1997 2 15 1997 2 15 0 1

1997 Journal of Clinical Investigation

125345. School injuries in an occupational health perspective: what do we learn from community based epidemiological studies? Full Text available with Trip Pro

School injuries in an occupational health perspective: what do we learn from community based epidemiological studies? The paper reviews community based epidemiological studies of injuries at school. It discusses their main findings in the light of a frame of analysis that emphasizes multidimensionality of causes, and in a Swedish context, where school injuries are legally regarded as occupational injuries.A frame of analysis, inspired by research in the arena of occupational accident (...) , was developed. It employs four key concepts to distinguish between injury and accident sequence, and between situational and structural factors as potential injury determinants. It also stresses the interaction between pupil, school, and community, in injury genesis. In parallel, a review of community based epidemiological studies of school injuries was undertaken after searching the relevant literature. The knowledge gathered from these studies is appraised in the light of the frame of analysis.In general

1997 Injury Prevention

125346. Evidence-Based Approach to the Medical Literature Full Text available with Trip Pro

Evidence-Based Approach to the Medical Literature 9127238 1997 07 01 2018 11 13 0884-8734 12 Suppl 2 1997 Apr Journal of general internal medicine J Gen Intern Med Evidence-based approach to the medical literature. S5-14 Fletcher R H RH Department of Ambulatory Care and Prevention. Harvard Medical School/Harvard Pilgrim Health Care, Boston, MA 02115, USA. Fletcher S W SW eng Journal Article Review United States J Gen Intern Med 8605834 0884-8734 IM Computer Communication Networks Education (...) , Medical, Continuing Evidence-Based Medicine Guidelines as Topic Humans Information Services Information Storage and Retrieval Information Systems Journalism, Medical MEDLINE Medical Informatics Applications Medical Informatics Computing Physician-Patient Relations United States 22 1997 4 1 1997 4 1 0 1 1997 4 1 0 0 ppublish 9127238 PMC1497222 Ann Intern Med. 1993 May 1;118(9):731-7 8460861 N Engl J Med. 1992 Jul 23;327(4):248-54 1614465 N Engl J Med. 1993 Sep 9;329(11):745-52 8350883 Ann Intern Med

1997 Journal of General Internal Medicine

125347. The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument. Full Text available with Trip Pro

The Boston AIDS Survival Score (BASS): a multidimensional AIDS severity instrument. This study developed a new acquired immunodeficiency syndrome (AIDS) severity system by including diagnostic, physiological, functional, and sociodemographic factors predictive of survival.Three-hundred five persons with AIDS in Boston were interviewed; their medical records were reviewed and vital status ascertained.Overall median (+/- SD) survival for the cohort from the first interview until death was 560 (...) , 3.21; any basic limitations, RH = 2.60, 95% CI = 1.44, 4.69). This model had substantially greater predictive power (R2 = .17, C statistic = .68) than the Justice score alone (R2 = .09, C statistic = .61).Incorporating data on clinically important events and functional status into a physiologically based system can improve the prediction of survival with AIDS.

1997 American Journal of Public Health

125348. Fat digestion in the neonate Full Text available with Trip Pro

Fat digestion in the neonate 9175955 1997 06 26 2018 11 13 1359-2998 76 3 1997 May Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Fat digestion in the neonate. F206-11 Manson W G WG Department of Child Health, Royal Hospital for Sick Children, Glasgow. Weaver L T LT eng Journal Article Review England Arch Dis Child Fetal Neonatal Ed 9501297 1359-2998 0 Dietary Fats 0 Fatty Acids 0 Triglycerides EC 3.1.1.3 Lipase AIM IM Dietary Fats metabolism (...) Digestion physiology Digestive System Physiological Phenomena Fatty Acids metabolism Humans Infant, Newborn physiology Lipase metabolism Milk, Human chemistry Triglycerides metabolism 49 1997 5 1 1997 5 1 0 1 1997 5 1 0 0 ppublish 9175955 PMC1720654 J Pediatr. 1992 Apr;120(4 Pt 2):S56-61 1343204 Adv Pediatr. 1982;29:33-67 6758535 Brain Res. 1973 Feb 28;50(2):341-51 4705503 Gastroenterology. 1986 Oct;91(4):919-25 3743968 Arch Dis Child. 1993 Sep;69(3):366-70 8215547 J Clin Invest. 1966 Feb;45(2):217-27

1997 Archives of disease in childhood Fetal and neonatal edition

125349. Use of neonatal intensive care unit as a safe place for neonatal surgery Full Text available with Trip Pro

Use of neonatal intensive care unit as a safe place for neonatal surgery To evaluate the advantages, disadvantages, and short term morbidity and mortality of major surgical interventions performed in the neonatal intensive care unit.A retrospective case review of 45 neonates was performed from April 1991 to September 1995. The characteristics of the patients were: gestational age 29 (SD 4) weeks (range 24 to 41 weeks); birth-weight 1305 (870) g (range 540 to 4040 g); presurgical weight 1430 (...) at laparotomy was: bowel resection with stomas (n = 8) and stomas (n = 4). No specially designed area was used to perform surgery.Local or systemic infection associated with surgery was not seen and no perioperative mortality was related to the surgical procedure.The neonatal intensive care unit is suitable for major surgery during the neonatal period and no special area is needed to perform complication free surgery.

1997 Archives of disease in childhood Fetal and neonatal edition

125350. Ocular non-Hodgkin's lymphoma: a clinical study of nine cases Full Text available with Trip Pro

Ocular non-Hodgkin's lymphoma: a clinical study of nine cases Primary oculocerebral large cell malignant non-Hodgkin's lymphoma, formerly called ocular reticulum cell sarcoma, runs a uniformly fatal course. Once the central nervous system (CNS) is involved, survival without treatment is very limited. Although treatment does not substantially improve the long term survival, it provides short term improvement in these patients.The charts of all patients with ocular involvement of non-Hodgkin's (...) lymphoma followed during the period 1984-93 were reviewed. The diagnosis of non-Hodgkin's lymphoma was made by different diagnostic approaches: CNS biopsy, anterior chamber tap, vitrectomy, haematology, and necropsy.Eight patients had oculocerebral large cell and one had small cell non-Hodgkin's lymphoma. Five patients with pure ocular localisation had initially received steroid treatment for intermediate uveitis. First diagnosis was made on CNS biopsy in three, anterior chamber tap in one, vitreous

1997 The British journal of ophthalmology

125351. Comparison of antinuclear antibody testing methods: immunofluorescence assay versus enzyme immunoassay. Full Text available with Trip Pro

Comparison of antinuclear antibody testing methods: immunofluorescence assay versus enzyme immunoassay. Performances of anti-nuclear antibody testing by immunofluorescence assay (ANA-IFA) and enzyme immunoassay (ANA-EIA) were compared in relation to patient diagnosis. A total of 467 patient serum samples were tested by ANA-IFA (Kallestad; Sanofi) and ANA-EIA (RADIAS; Bio-Rad), and their age, sex, diagnosis, disease status, and medications were obtained through chart review. Reference ranges (...) were established by testing 98 healthy blood donor samples. Eighty-six samples came from patients with diffuse connective tissue diseases, including systemic lupus erythematosus, discoid lupus erythematosus, or drug-induced lupus (n = 71); systemic sclerosis, CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal motility abnormalities, sclerodactyly, and telangiectasia), or Raynaud's syndrome (n = 8); Sjögren's syndrome (n = 5); mixed connective tissue disease (n = 5); and polymyositis

1997 Clinical and Diagnostic Laboratory Immunology

125352. Recent advances. HIV infection-II. Full Text available with Trip Pro

Recent advances. HIV infection-II. 9055720 1997 04 03 2008 11 20 0959-8138 314 7080 1997 Feb 22 BMJ (Clinical research ed.) BMJ Recent advances. HIV infection-II. 579-83 Beiser C C Institute of Human Virology, University of Maryland Medical System, Baltimore, USA. eng Journal Article Review England BMJ 8900488 0959-8138 AIM IM X AIDS-Related Opportunistic Infections complications prevention & control Cytomegalovirus Retinitis complications prevention & control Developing Countries Humans

1997 BMJ : British Medical Journal

125353. Poor education linked with teen pregnancies. Full Text available with Trip Pro

Poor education linked with teen pregnancies. 9055705 1997 04 03 2008 11 20 0959-8138 314 7080 1997 Feb 22 BMJ (Clinical research ed.) BMJ Poor education linked with teen pregnancies. 537 Westall J J eng News England BMJ 8900488 0959-8138 AIM IM J Adolescent Educational Status Female Humans Pregnancy Pregnancy in Adolescence 122799 00266539 Two reports concerning socioeconomic factors associated with adolescent pregnancy have been released: a study from the NHS Centre for Reviews (...) . Teenage pregnancy in both reports was associated with poor social, economic, and health outcomes for mother and child. According to the second report, the risk of maternal death during childbirth is 2-4 times greater for mothers 17 and younger, in comparison to mothers age 20 and older. Dr. Kathleen Kiernan, a senior research fellow at the London School of Economics, blames Britain's high adolescent pregnancy rate on an educational system that allows 16-year olds to leave school for a low-paying job

1997 BMJ : British Medical Journal

125354. Obtaining useful information from expert based sources. Full Text available with Trip Pro

Obtaining useful information from expert based sources. Clinicians rely heavily on expert based systems-consultation with colleagues, journal reviews and textbooks, and continuing education activities-to obtain new information. The usefulness of sources such as these depends on the relevance and validity of the information and the work it takes to obtain it. Useful information can be distinguished from the useless by asking three questions: Does the information focus on an outcome that my

1997 BMJ : British Medical Journal

125355. The science of nebulised drug delivery Full Text available with Trip Pro

The science of nebulised drug delivery 9155849 1997 06 04 2018 11 13 0040-6376 52 Suppl 2 1997 Apr Thorax Thorax The science of nebulised drug delivery. S31-44 O'Callaghan C C Department of Child Health, University of Leicester, Leicester Royal Infirmary, UK. Barry P W PW eng Journal Article Research Support, Non-U.S. Gov't Review England Thorax 0417353 0040-6376 0 Aerosols 0 Bronchodilator Agents IM Administration, Inhalation Aerosols Asthma drug therapy Bronchodilator Agents administration (...) & dosage therapeutic use Drug Delivery Systems Equipment Design Humans Nebulizers and Vaporizers Ultrasonics 104 1997 4 1 1997 4 1 0 1 1997 4 1 0 0 ppublish 9155849 PMC1765865 Thorax. 1986 May;41(5):364-8 3750243 Br J Clin Pharmacol. 1993 Sep;36(3):211-4 9114906 J Laryngol Otol. 1987 Feb;101(2):127-32 3572216 Thorax. 1987 Mar;42(3):190-4 3303427 Lancet. 1988 Jan 16;1(8577):126 2891972 Thorax. 1990 Feb;45(2):109-11 2315873 Respiration. 1989;56(3-4):220-6 2635351 Chest. 1990 Jun;97(6):1327-32 2347217

1997 Thorax

125356. Nebuliser therapy in the intensive care unit Full Text available with Trip Pro

Nebuliser therapy in the intensive care unit 9155853 1997 06 04 2018 11 13 0040-6376 52 Suppl 2 1997 Apr Thorax Thorax Nebuliser therapy in the intensive care unit. S56-9 O'Doherty M J MJ Department of Nuclear Medicine, St. Thomas' Hospital, London, UK. Thomas S H SH eng Journal Article Review England Thorax 0417353 0040-6376 IM Critical Care methods Drug Delivery Systems Humans Lung Diseases drug therapy Nebulizers and Vaporizers Respiration, Artificial 46 1997 4 1 1997 4 1 0 1 1997 4 1 0 0

1997 Thorax

125357. Grapefruits and drugs: when is statistically significant clinically significant? Full Text available with Trip Pro

Grapefruits and drugs: when is statistically significant clinically significant? 9153265 1997 06 17 2013 11 21 0021-9738 99 10 1997 May 15 The Journal of clinical investigation J. Clin. Invest. Grapefruits and drugs: when is statistically significant clinically significant? 2297-8 Abernethy D R DR eng Comment Editorial Review United States J Clin Invest 7802877 0021-9738 9035-51-2 Cytochrome P-450 Enzyme System EC 1.14.14.1 Aryl Hydrocarbon Hydroxylases EC 1.14.14.1 Cytochrome P-450 CYP3A EC (...) 1.5.- Oxidoreductases, N-Demethylating I9ZF7L6G2L Nifedipine OL961R6O2C Felodipine AIM IM J Clin Invest. 1997 May 15;99(10):2545-53 9153299 Animals Aryl Hydrocarbon Hydroxylases Beverages Citrus Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System metabolism Felodipine blood pharmacokinetics Humans Metabolic Clearance Rate Nifedipine blood pharmacokinetics Oxidoreductases, N-Demethylating metabolism Pharmacokinetics Smoking 14 1997 5 15 1997 5 15 0 1 1997 5 15 0 0 ppublish 9153265 10.1172

1997 Journal of Clinical Investigation

125358. Expansive lumbar laminoplasty for degenerative spinal stenosis in patients below 70 years of age Full Text available with Trip Pro

Expansive lumbar laminoplasty for degenerative spinal stenosis in patients below 70 years of age We reviewed the clinical and radiological results of patients with lumbar degenerative spinal stenosis who underwent expansive laminoplasty with a mean follow-up term of 5.6 years. Twenty-seven patients underwent open-door-type expansive lumbar laminoplasty, which has both decompression and stabilization effects. Clinical results were assessed based on the score system devised by the Japanese

1997 European Spine Journal

125359. Teleradiology for remote diagnosis: A prospective multi-year evaluation Full Text available with Trip Pro

Teleradiology for remote diagnosis: A prospective multi-year evaluation Teleradiology has been used for nearly 3 years at our institution to provide urgent radiologic interpretations for two outpatient clinics and an affiliated hospital. The purpose of this study was to evaluate the clinical reliability of the existing system. Teleradiology images were interpreted using 1600 x 1200 pixel display stations. The original films from the same cases were subsequently interpreted, usually by another (...) radiologist. The initial and final interpretations were compared. Discrepancies were rated and adjudicated by another senior radiologist. These data were compared to peer review interobserver discrepancy rates. Among the 2688 teleradiology examinations evaluated, there were major discrepancies in 31 (1.5%). In three instances teleradiology rather than film interpretation was considered correct. Abnormalities missed on teleradiology were apparent in all but two at adjudication. Among the 628 peer-review

1997 Journal of Digital Imaging

125360. Effect of repair strategy on hospital cost for infants with tetralogy of Fallot. Full Text available with Trip Pro

, the two-stage approach is standard practice for infants younger than 1 year of age or is used selectively in patients with an anomalous coronary artery across the right ventricular outflow tract (RVOT), "small pulmonary arteries," multiple congenital anomalies, critical illnesses (CI), which increase the risk of bypass (e.g., sepsis or DIC), or severe hypercyanotic spells (HS) at the time of presentation. The cost implications of these two approaches are unknown.The authors reviewed 22 patients (...) patient) and CI (one patient). In the 18 patients undergoing 1 degree repair, 3 (16.6%) presented with HS, 6 (33.3%) had a transanular repair, and 6 (33.3%) were able to be repaired through an entirely transatrial approach (youngest patient, 1.5 months). The HC (1996 dollars) and hospital length of stay (LOS; days) were evaluated for all patients. The HCs were calculated using transition I, which is a cost accounting system used by our medical center since July 1992. Transition I provides complete

1997 Annals of Surgery

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