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101. Do either early warning systems or emergency response teams improve hospital patient survival? A systematic review

Do either early warning systems or emergency response teams improve hospital patient survival? A systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2014 DARE.

102. Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness

Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness | CADTH.ca Find the information you need Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Last updated: September 6, 2019 Project Number: RC1175-000 Product Line: Research Type: Devices and Systems (...) population.One economic evaluation was identified that suggested there was a net benefit to the Spanish national health system when pharmacists carried out medication review with follow-up among patients 65 years or older taking 5 or more medications. Differences in the healthcare delivery models and unit costs between Spain and Canada should be considered when generalizing results for the Canadian context. Files Rapid Response Summary with Critical Appraisal Published : September 6, 2019 Follow us: © 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

103. Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines

-Effectiveness and Guidelines Last updated: August 20, 2019 Project Number: RC1171-000 - CI0058-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical utility of multidisciplinary medication review every three months in long-term care settings? What is the cost-effectiveness of multidisciplinary medication review every three months in long-term care settings? What are the evidence-based guidelines regarding the use (...) Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

104. Impact of financial inclusion in low? and middle?income countries: A systematic review of reviews Full Text available with Trip Pro

Impact of financial inclusion in low? and middle?income countries: A systematic review of reviews Impact of financial inclusion in low‐ and middle‐income countries: A systematic review of reviews - Duvendack - 2019 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Impact of financial inclusion in low‐ and middle‐income countries (...) : A systematic review of reviews Corresponding Author E-mail address: School of International Development, University of East Anglia, Norwich, NR4 7TJ UK Correspondence Maren Duvendack, University of East Anglia, School of International Development, Norwich Research Park, Norwich NR4 7TJ, UK. Email: Philip Mader, Institute of Development Studies, Library Road, University of Sussex, Brighton, East Sussex BN19RE, UK. Email: Corresponding Author E-mail address: Institute of Development Studies, University

2019 Campbell Collaboration

105. superDimension Navigation System to help diagnostic sampling of peripheral lung lesions

unquantifiable instances of multiple-counting of patients in the systematic reviews. T able 2 summarises the clinical evidence as well as its strengths and limitations. Overall assessment of the evidence The body of evidence for superDimension Navigation System is large, with several systematic reviews and meta-analyses including a large number of primary studies and thousands of patients worldwide, although none in a UK setting. Primary outcomes include diagnostic yield and safety parameters (...) . (2018) superDimension Navigation System to help diagnostic sampling of peripheral lung lesions (MIB194) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 7 of 17Study size, design and location Systematic review with limited meta-analysis (search dates January 2000 to November 2017). n=1,648 ENB cases from 31 selected studies. China. Intervention and comparator(s) ENB biopsy of lesion in lung parenchyma and mediastinal

2019 National Institute for Health and Clinical Excellence - Advice

106. Prevena incision management system for closed surgical incisions

Prevena incision management system for closed surgical incisions Pre Prev vena incision management system for closed ena incision management system for closed surgical incisions surgical incisions Medtech innovation briefing Published: 28 February 2019 www.nice.org.uk/guidance/mib173 pathways Summary Summary The technology technology described in this briefing is Prevena. It is a single-use technology for the management of closed surgical incisions that may be at increased risk of infection (...) #notice-of-rights). Page 1 of 12considered in this briefing. The technology The technology Prevena (Kinetic Concepts Inc. an Acelity Company) is a wound management system that is placed over a closed surgical incision. The device applies continuous negative pressure. This helps promote healing by holding the incision edges together, drawing fluid and exudate out of the wound, reducing oedema and stimulating perfusion. The device is single use and can stay in place for up to 7 days. Prevena

2019 National Institute for Health and Clinical Excellence - Advice

107. Systemic Pharmacologic Therapies for Low Back Pain: A Systematic Review for an American College of Physicians Clinical Practice Guideline. Full Text available with Trip Pro

Systemic Pharmacologic Therapies for Low Back Pain: A Systematic Review for an American College of Physicians Clinical Practice Guideline. A 2007 American College of Physicians guideline addressed pharmacologic options for low back pain. New evidence and medications have now become available.To review the current evidence on systemic pharmacologic therapies for acute or chronic nonradicular or radicular low back pain.Ovid MEDLINE (January 2008 through November 2016), Cochrane Central Register (...) of Controlled Trials, Cochrane Database of Systematic Reviews, and reference lists.Randomized trials that reported pain, function, or harms of systemic medications versus placebo or another intervention.One investigator abstracted data, and a second verified accuracy; 2 investigators independently assessed study quality.The number of trials ranged from 9 (benzodiazepines) to 70 (nonsteroidal anti-inflammatory drugs). New evidence found that acetaminophen was ineffective for acute low back pain, nonsteroidal

2017 Annals of Internal Medicine

108. Neurotransmitter systems involved in placebo and nocebo effects in healthy participants and patients with chronic pain: a systematic review. (Abstract)

Neurotransmitter systems involved in placebo and nocebo effects in healthy participants and patients with chronic pain: a systematic review. The investigation of neurotransmitter systems in placebo and nocebo effects has improved our understanding of these phenomena. Yet, most studies involve healthy participants. Because the pain modulatory system may differ in healthy participants and patients with chronic pain, it is important to investigate the evidence for neurotransmitter involvement (...) way in specifying the neurotransmitter systems involved in placebo effects in healthy participants. Yet, evidence for the involvement of neurotransmitter systems in placebo effects in patients with chronic pain and in nocebo effects in healthy participants and patients is scarce. Based on the existing evidence, this systematic review suggests that knowledge obtained in healthy participants may not necessarily be transferred to chronic pain.

2019 Pain

109. Clinical Characteristics and Risk Factors of Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus: a Systematic Review and Meta-Analysis Based on Observational Studies. (Abstract)

Clinical Characteristics and Risk Factors of Diffuse Alveolar Hemorrhage in Systemic Lupus Erythematosus: a Systematic Review and Meta-Analysis Based on Observational Studies. Diffuse alveolar hemorrhage (DAH) is a rare but potentially deadly manifestation of systemic lupus erythematosus (SLE). The aim of this study was to investigate the clinical characteristics and risk factors of DAH in SLE. A systematic review and meta-analysis of previous observational studies compared the clinical

2019 Clinical Reviews in Allergy & Immunology

110. Use of Topical and Systemic Retinoids in Solid Organ Transplant Recipients: Update and Review of the Current Literature. (Abstract)

Use of Topical and Systemic Retinoids in Solid Organ Transplant Recipients: Update and Review of the Current Literature. Solid organ transplant recipients (SOTRs) are at an increased risk of epithelial malignancies, mainly squamous cell carcinoma, and its precursor lesions such as actinic keratoses, warts, and porokeratosis, which may respond to retinoid therapy.To review the published evidence on the efficacy and safety of topical and systemic retinoids for the treatment and prophylaxis (...) of malignant and premalignant conditions that mostly afflict SOTRs.Systematic review of the literature to summarize the level of evidence and grade of recommendation for retinoid therapy with emphasis in the SOTR population.Acitretin has the highest strength of recommendation (Grade A) for prophylaxis of nonmelanoma skin cancer (NMSC) and treatment and prophylaxis of actinic keratoses in SOTR. In nonimmunosuppressed patients, acitretin and isotretinoin have a Grade B recommendation for treatment

2019 Dermatologic Surgery

111. From Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week. (Abstract)

From Focal Lipid Storage to Systemic Inflammation: JACC Review Topic of the Week. Concepts of atherogenesis have evolved considerably with time. Early animal experiments showed that a cholesterol-rich diet could induce fatty lesion formation in arteries. The elucidation of lipoprotein metabolism ultimately led to demonstrating the clinical benefits of lipid lowering. The view of atheromata as bland accumulations of smooth muscle cells that elaborated an extracellular matrix that could entrap

2019 Journal of the American College of Cardiology

112. A review of measurement practice in studies of clinical decision support systems 1998-2017. Full Text available with Trip Pro

A review of measurement practice in studies of clinical decision support systems 1998-2017. To assess measurement practice in clinical decision support evaluation studies.We identified empirical studies evaluating clinical decision support systems published from 1998 to 2017. We reviewed titles, abstracts, and full paper contents for evidence of attention to measurement validity, reliability, or reuse. We used Friedman and Wyatt's typology to categorize the studies.There were 391 studies (...) in problem impact studies with the majority of measures being clinical or patient reported outcomes with validity measured elsewhere.Measurement methodology is frequently ignored in empirical studies of clinical decision support systems and particularly so in field user effect studies. Authors may in fact be attending to measurement considerations and not reporting this or employing methods of unknown validity and reliability in their studies. In the latter case, reported study results may be biased

2019 Journal of the American Medical Informatics Association

113. Herb induced liver injury after using herbal medicine: A systemic review and case-control study. Full Text available with Trip Pro

Herb induced liver injury after using herbal medicine: A systemic review and case-control study. In Taiwan, traditional herbal medication was included in Taiwan's National Health Insurance (NHI) system since 1996 and in 9 out of 10 hospitals have developed their own departments of traditional medicine. This study aims to address the herb-induced liver injury (HILI) after using herbal medicine on the relationship between age, gender, epidemiology, laboratory data, pathogenesis, mobility (...) , and mortality.We searched the PubMed database with "hepatitis after herbal medicine" and "in human" till 2018 April and returned 163 articles in a systemic review manner. Two cases reports describing in-vitro liver injury were excluded. Reviews and articles without the detailed report, laboratory data and history were excluded from this study. In the end, there were 53 articles enrolled in this study. These enrolled literatures are from France (n = 13), Germany (n = 12), Switzerland (n = 5) United States

2019 Medicine

114. Acupuncture for perioperative care of total hip arthroplasty: A systemic review of controlled trials and meta-analysis. Full Text available with Trip Pro

Acupuncture for perioperative care of total hip arthroplasty: A systemic review of controlled trials and meta-analysis. This protocol is intended to conduct a systematic review and meta-analysis to evaluate the efficacy and safety of acupuncture in perioperative care of total hip arthroplasty patients.The following databases will be searched from their inception to November 2018 without language restrictions: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Cumulative (...) Index to Nursing and Allied Health Literature, Oriental Medicine Advanced Searching Integrated System, Korean Traditional Knowledge Portal, KoreaMed, DBPIA, Research Information Service System, including the China National Knowledge Infrastructure. Any randomized controlled trials related to perioperative care of total hip arthroplasty will be included. The primary outcomes of this study are dosage of analgesics and pain intensity. For secondary outcomes, Harris hip score, incidence of postoperative

2019 Medicine

115. Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis. Full Text available with Trip Pro

Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: A systematic review and meta-analysis. Dyslipidemia is a common disorder in systemic lupus erythematosus (SLE) patients. It is still inconclusive whether antimalarial drugs could affect the serum lipids in SLE patients, therefore we conducted a systematic review and meta-analysis of available data to address this issue.We comprehensively searched the databases of PubMed, EMBASE and Cochrane Library from (...) date of inception to Sep 2018 for both randomized controlled trials (RCTs) and observational studies. Review Manager 5.3 software was used for analysis. We performed meta-analysis using random-effects model and weighted the mean difference (WMD) and its 95% confidence interval (CI). The Q test was used to assess the presence of heterogeneity and the I index was used to quantify the extent of heterogeneity.In total, 8 studies met our selection criteria including 2 RCTs, 2 cohort studies, and 4 case

2019 Medicine

116. Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. Full Text available with Trip Pro

Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. Nasal surgeries (such as Functional Endoscopic Sinus Surgery, Rhinoplasty, and Septorhinoplasty) are popular procedures. But perioperative bleeding, eyelid edema, and periorbital ecchymosis remain problems. Tranexamic acid (TXA) is an antifibrinolytic, and it was used to reduce the perioperative bleeding. However, there is no enough evidence judging its safety and efficiency. Therefore

2019 Medicine

117. Implementing advance care planning with community-dwelling frail elders requires a system-wide approach: An integrative review applying a behaviour change model. Full Text available with Trip Pro

Implementing advance care planning with community-dwelling frail elders requires a system-wide approach: An integrative review applying a behaviour change model. Facilitating advance care planning with community-dwelling frail elders can be challenging. Notably, frail elders' vulnerability to sudden deterioration leads to uncertainty in recognising the timing and focus of advance care planning conversations.To understand how advance care planning can be better implemented for community-dwelling (...) frail elders and to develop a conceptual model to underpin intervention development.A structured integrative review of relevant literature.CINAHL, Embase, Ovid Medline, PsycINFO, Cochrane Library, and University of York Centre for Reviews and Dissemination. Further strategies included searching for policy and clinical documents, grey literature, and hand-searching reference lists. Literature was searched from 1990 until October 2018.From 3043 potential papers, 42 were included. Twenty-nine were

2019 Palliative medicine

118. Understanding patient engagement in health system decision-making: a co-designed scoping review. Full Text available with Trip Pro

Understanding patient engagement in health system decision-making: a co-designed scoping review. With healthcare striving to shift to a more person-centered delivery model, patient and family involvement must have a bigger role in shaping this. While many initiatives involving patients and family members focus on self-care, a broader understanding of patient participation is necessary. Ensuring a viable and sustainable critical number of qualified patients and family members to support (...) this shift will be of utmost importance. The purpose of this study was to understand how health systems are intentionally investing in the training and skill development of patients and family members.Patient co-investigators and researchers conducted a scoping review of the existing literature on methods adopted by healthcare systems to build the skills and capacity of patients to participate in healthcare decision-making using a recognized methodological framework. Six electronic databases were

2019 Systematic reviews

119. The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol. Full Text available with Trip Pro

The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol. Low back pain is the greatest contributor to the global burden of disease and can result in work disability. Previous literature has examined the influence of personal factors, the healthcare system, workplace, and income support systems on work disability due to low back pain. Income support systems may also influence healthcare and the workplace, leading (...) to an impact on healthcare quality and functional capacity. However, there has been little insight as to how or in what contexts this influence occurs. This realist review aims to provide an explanation of how and in what contexts income support systems impact the healthcare quality and functional capacity of people who are unable to work due to low back pain.Realist reviews are a type of literature review that seek to determine how and in what contexts a social programme such as income support leads

2019 Systematic reviews

120. Systemic therapy in cervical cancer: 30 years in review. (Abstract)

Systemic therapy in cervical cancer: 30 years in review. Advanced-inoperable cervical cancer is a challenging entity due to increased percentage of locoregional and distant recurrences. Furthermore, recurrent cervical cancer not amenable to radical treatment as well as de novo metastatic disease are considered incurable with dismal prognosis. Well-designed clinical trials conducted during the last 30 years have revealed the active chemotherapeutic agents as well as their optimal combinations

2019 Critical reviews in oncology/hematology

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