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Review of Systems

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101. A posteriori dietary patterns and their association with systemic low-grade inflammation in adults: a systematic review and meta-analysis. (Abstract)

A posteriori dietary patterns and their association with systemic low-grade inflammation in adults: a systematic review and meta-analysis. A posteriori dietary patterns are promising ways of uncovering potential public health strategies for the prevention of systemic, low-grade, inflammation-related, chronic noncommunicable diseases.To investigate and summarize the current evidence on the association between a posteriori dietary patterns and systemic, low-grade inflammation in adults.MEDLINE

2020 Nutrition reviews

102. Psychosocial Interventions and Immune System Function: A Systematic Review and Meta-analysis of Randomized Clinical Trials. (Abstract)

Psychosocial Interventions and Immune System Function: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Recent estimates suggest that more than 50% of all deaths worldwide are currently attributable to inflammation-related diseases. Psychosocial interventions may represent a potentially useful strategy for addressing this global public health problem, but which types of interventions reliably improve immune system function, under what conditions, and for whom are unknown.To (...) address this issue, we conducted a systematic review and meta-analysis of randomized clinical trials (RCTs) in which we estimated associations between 8 different psychosocial interventions and 7 markers of immune system function, and examined 9 potential moderating factors.PubMed, Scopus, PsycInfo, and ClinicalTrials.gov databases were systematically searched from February 1, 2017, to December 31, 2018, for all relevant RCTs published through December 31, 2018.Eligible RCTs included a psychosocial

2020 JAMA psychiatry (Chicago, Ill.)

103. A review of endoscopic scoring systems and their importance in a treat-to-target approach in inflammatory bowel disease (with videos). (Abstract)

A review of endoscopic scoring systems and their importance in a treat-to-target approach in inflammatory bowel disease (with videos). Endoscopic assessment is currently the criterion standard for the diagnosis and assessment of mucosal disease activity, prognosis and monitoring for dysplasia, and assessment of response to therapy. Wider appreciation of the potential disconnect between symptoms and objective measures of disease activity and evidence that uncontrolled inflammation may lead (...) and aid standardization with reporting of mucosal appearance, augmenting clinical decision making. A plethora of scoring systems exist to define activity, response, and remission in both Crohn's disease and ulcerative colitis. In this review, we discuss the most commonly used endoscopic scoring systems and proposed definitions of response and remission, and how they can be integrated into a treat-to-target approach to optimize patient outcomes.Copyright © 2020 American Society for Gastrointestinal

2020 Gastrointestinal endoscopy

104. Systematic review of the role of renin-angiotensin system inhibitors in late studies on Covid-19: A new challenge overcome? Full Text available with Trip Pro

Systematic review of the role of renin-angiotensin system inhibitors in late studies on Covid-19: A new challenge overcome? A role for the renin-angiotensin-aldosterone-system in Severe Acute Respiratory Syndrome-Coronavirus-2 infection and in the development of COronaVIrus Disease-19 disease has generated remarkable concerns among physicians and patients. Even though a suggestive pathophysiological link between renin-angiotensin-aldosterone-system and the virus has been proposed, its (...) pathogenic role remains very difficult to be defined. Although COronaVIrus Disease-19 targets preferentially older people with high prevalence of hypertension and extensive use of renin-angiotensin-aldosterone-system inhibitors, an independent role for hypertension and its therapies is not defined. In this article, we scrutinize evidence from the most representative available studies in which the potential role of renin-angiotensin system inhibitors, specifically angiotensin-converting enzyme inhibitors

2020 International journal of cardiology

105. Cardiac resynchronization therapy for the failing systemic right ventricle: A systematic review. Full Text available with Trip Pro

Cardiac resynchronization therapy for the failing systemic right ventricle: A systematic review. Patients with a systemic right ventricle (SRV) are at high risk for development of heart failure early in life. An SRV is encountered in patients with congenitally corrected transposition of the great arteries (CCTGA) or dextro-transposition of the great arteries (DTGA) with previous atrial switch repair (Mustard or Senning procedure). Progressive heart failure is one of the leading cause (...) disease consider CRT to be 'experimental' in this population. This systematic review critically summarizes current literature on CRT in SRV patients and provides future perspectives for further research in this challenging and growing CHD population.Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

2020 International journal of cardiology

106. Effectiveness and Safety of Systemic Therapy for Psoriasis in Older Adults: A Systematic Review. (Abstract)

Effectiveness and Safety of Systemic Therapy for Psoriasis in Older Adults: A Systematic Review. Treating older adults with psoriasis can be challenging owing to comorbidities, concomitant medication use, and consequent safety risks. Although many studies focus on the effectiveness and safety of systemic antipsoriatic therapies in the general population, their effectiveness in older adults with psoriasis has not been systematically assessed.To evaluate the effectiveness and safety of systemic (...) antipsoriatic therapies in patients 65 years or older.A systematic literature search was conducted in Embase, MEDLINE, and the Cochrane Central Register of Controlled Trials (CENTRAL) on November 11, 2019. No date limit was used. Randomized clinical trials, cohort studies, large case series, and meta-analyses assessing efficacy (or effectiveness) and/or safety of systemic antipsoriatic therapies in patients 65 years or older were included.The initial search yielded 11 096 results, of which 31 unique

2020 JAMA dermatology (Chicago, Ill.)

107. Inclusion of Older Adults in Randomized Clinical Trials for Systemic Medications for Atopic Dermatitis: A Systematic Review. (Abstract)

Inclusion of Older Adults in Randomized Clinical Trials for Systemic Medications for Atopic Dermatitis: A Systematic Review. Despite increasing evidence that atopic dermatitis is common in older adults, it is unclear whether the evidence base for treating atopic dermatitis with systemic therapy is generalizable to that population. Older adults are most at risk for adverse events from medications, given age-related alterations in drug metabolism, increased comorbidity, and polypharmacy.This (...) systematic review examines the representation of older adults in randomized clinical trials (RCTs) of systemic immunomodulatory treatments for atopic dermatitis and whether safety and efficacy data are reported specifically for older individuals.The Cochrane Central Register of Controlled Trials, Embase, MEDLINE databases, and the ClinicalTrials.gov trial register were searched from inception (MEDLINE via Ovid, 1946; Embase via Ovid, 1974) to November 7, 2019. RCTs investigating systemic immunomodulatory

2020 JAMA dermatology (Chicago, Ill.)

108. Improving quality of surgical and anaesthesia care at hospital level in sub-Saharan Africa: a systematic review protocol of health system strengthening interventions. Full Text available with Trip Pro

Improving quality of surgical and anaesthesia care at hospital level in sub-Saharan Africa: a systematic review protocol of health system strengthening interventions. Over 5 billion people in the world do not have access to safe, affordable surgical and anaesthesia care when needed. In order to improve health outcomes in patients with surgical conditions, both access to care and the quality of care need to be improved. A recent commission on high-quality health systems highlighted that poor (...) -quality care is now a bigger barrier than non-utilisation of the health system for reducing mortality.To carry out a systematic review to provide an evidence-based summary of hospital-based interventions associated with improved quality of surgical and anaesthesia care in sub-Saharan African countries (SSACs).Three search strings (1) surgery and anaesthesia, (2) quality improvement hospital-based interventions and (3) SSACs will be combined. The following databases EMBASE, Global Health, MEDLINE

2020 BMJ open

109. Built to last? The sustainability of healthcare system improvements, programmes and interventions: a systematic integrative review. Full Text available with Trip Pro

Built to last? The sustainability of healthcare system improvements, programmes and interventions: a systematic integrative review. The sustainability of healthcare delivery systems is challenged by ageing populations, complex systems, increasing rates of chronic disease, increasing costs associated with new medical technologies and growing expectations by healthcare consumers. Healthcare programmes, innovations and interventions are increasingly implemented at the front lines of care (...) articles (July 2011-March 2018). Articles were included if they assessed programme sustainability or sustained outcomes of a programme at the healthcare system level. Six reviewers conducted the abstract and full-text review. Data were extracted on study characteristics, definitions, terminology, theoretical frameworks, methods and tools. Hawker's Quality Assessment Tool was applied to included studies.Of the 92 included studies, 75.0% were classified as high quality. Twenty-seven (29.3%) studies

2020 BMJ open

110. Systemic inflammatory markers in neck pain: a systematic review with meta-analysis. Full Text available with Trip Pro

Systemic inflammatory markers in neck pain: a systematic review with meta-analysis. Mechanisms underpinning symptoms in non-traumatic neck pain (NTNP) and whiplash-associated disorder (WAD) are not comprehensively understood. There is emerging evidence of systemic inflammation in musculoskeletal pain conditions, including neck and back pain. The aim of this systematic review was to determine if raised blood inflammatory markers are associated with neck pain.MEDLINE, EMBASE, Cochrane Library (...) , CINAHL and Web of Science databases were searched. Two independent reviewers identified studies for inclusion and extracted data. Meta-analysis was performed by random-effects model to calculate standard mean differences (SMDs). Risk of bias of individual studies was assessed using the Newcastle-Ottawa Scale. Overall quality of evidence from meta-analysis was assessed by Grades of Recommendation, Assessment, Development, and Evaluation approach.In total, ten studies were included comprising 706

2020 European Journal of Pain

111. Effect of Perioperative Active Body Surface Warming Systems on Analgesic and Clinical Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials. (Abstract)

Effect of Perioperative Active Body Surface Warming Systems on Analgesic and Clinical Outcomes: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Inadvertent perioperative hypothermia is a common complication of surgery, and active body surface warming (ABSW) systems are used to prevent adverse clinical outcomes. Prior data on certain outcomes are equivocal (ie, blood loss) or limited (ie, pain and opioid consumption). The objective of this study was to provide an updated (...) review on the effect of ABSW on clinical outcomes and temperature maintenance.We conducted a systematic review of randomized controlled trials evaluating ABSW systems compared to nonactive warming controls in noncardiac surgeries. Outcomes studied included postoperative pain scores and opioid consumption (primary outcomes) and other perioperative clinical variables such as temperature changes, blood loss, and wound infection (secondary outcomes). We searched Ovid MEDLINE daily, Ovid MEDLINE, EMBASE

2020 Anesthesia and Analgesia

112. Systemic therapy in the management of recurrent or metastatic salivary duct carcinoma: A systematic review. Full Text available with Trip Pro

Systemic therapy in the management of recurrent or metastatic salivary duct carcinoma: A systematic review. Salivary duct carcinoma (SDC) is an aggressive subtype of salivary gland cancer. Approximately half of SDC patients will develop recurrences or metastases. Therapeutic palliative therapy is therefore often needed. The majority of SDC tumors expresses the androgen receptor (AR) and one-third expresses human epidermal growth factor receptor 2 (HER2), both are potential therapeutic targets (...) . The aim of this paper is to systematically review and summarize the evidence on systemic palliative therapy for SDC and to provide treatment recommendations.Electronic libraries were systematically searched with a broad search strategy to identify studies where SDC patients received systemic therapy. Due to the rarity of SDC no restrictions were placed on study designs.The search resulted in 2014 articles of which 153 were full-text analyzed. Forty-five studies were included in the analysis, which

2020 Cancer Treatment Reviews

113. Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. Full Text available with Trip Pro

Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. The outbreak of the coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, spread worldwide after its emergence in China. Whether rich or poor, all nations are struggling to cope with this new global health crisis. The speed of the threat's emergence and the quick response required from public health authorities and the public itself makes (...) evident the need for a major reform in pandemic surveillance and notification systems. The development and implementation of a graded, individual-level pandemic notification system could be an effective tool to combat future threats of epidemics. This paper describes a prototype model of such a notification system and its potential advantages and challenges for implementation. Similar to other emergency alerts, this system would include a number of threat levels (level 1-5) with a higher level

2020 Journal of medical Internet research

114. Requirements of Health Data Management Systems for Biomedical Care and Research: Scoping Review. Full Text available with Trip Pro

Requirements of Health Data Management Systems for Biomedical Care and Research: Scoping Review. Over the last century, disruptive incidents in clinical and biomedical research fields have yielded a tremendous change in the health data management system. This is due to the breakthrough in the medical field and the need for big data analytics and the Internet of Things (IoT) to be incorporated in a real-time smart health information management system. In addition, the requirements of patient (...) ) medical record data, (2) real-time data access, (3) patient participation, (4) data sharing, (5) data security, (6) patient identity privacy, and (7) public insights. This paper reviews the health data management systems based on these 7 requirements across studies conducted over the years. To our knowledge, this is the first analysis of the temporal evolution of health data management systems giving insights on the system requirements for better health care.There is a need for a comprehensive real

2020 Journal of medical Internet research

115. Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: a systemic review and meta-analysis. (Abstract)

Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: a systemic review and meta-analysis. The ideal management for patients with cholecystocholedocholithiasis is still controversial. Laparoendoscopic rendezvous (LERV), combined with laparoscopy and endoscopy, is a novel and attractive technique. The aim of this research was to compare LERV with traditional two-stage management, preoperative ERCP and laparoscopic

2020 Surgical endoscopy

116. Staphylococcus saccharolyticus infection: case series with a PRISMA-compliant systemic review. Full Text available with Trip Pro

Staphylococcus saccharolyticus infection: case series with a PRISMA-compliant systemic review. Staphylococcus saccharolyticus is a rare cause of human infectious disease. The clinical characteristics and treatment of patients with S saccharolyticus infections remain largely unknown.We present the first reported case of empyema due to S saccharolyticus. In addition, a systematic review and pooled analysis of all S saccharolyticus cases were done to summarize the clinical and microbiological (...) characteristics and treatment of this rare pathogen.A case of empyema caused by S saccharolyticus diagnosed in study hospital was reported. This case and those identified from PubMed, EMBASE, and Web of Science were analyzed.In total, 8 patients were reviewed. The averages of the white blood cell count, sedimentation rate, and C-reactive protein were 16.8 × 10/L, 72 mm/h, and 176 mg/L, respectively. The average time-to-positivity of the anaerobic cultures was 5 days. The S saccharolyticus was resistant

2020 Medicine

117. Peri-implant fractures around hindfoot fusion nails: A systematic literature review and classification system. (Abstract)

Peri-implant fractures around hindfoot fusion nails: A systematic literature review and classification system. Tibio-talo calcaneal (TTC) arthrodesis is increasingly performed for hindfoot arthrosis and other indications. Peri-implant fracture around hindfoot fusion nails has been previously reported and can be problematic to treat given multiple surgical considerations including the status of hindfoot arthrodesis at time of fracture. We present a systematic review of the literature regarding (...) peri-implant fractures around hindfoot fusion nails and propose a classification system to help guide treatment based on findings from the current literature as well as the collective experience of the senior authors.A review of the literature was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to identify clinical investigations in which peri-implant fractures or other hardware failures were observed as complications following TTC

2020 Injury

118. Comparison of sputum induction and bronchoscopy in diagnosis of sputum smear-negative pulmonary tuberculosis: a systemic review and meta-analysis. Full Text available with Trip Pro

Comparison of sputum induction and bronchoscopy in diagnosis of sputum smear-negative pulmonary tuberculosis: a systemic review and meta-analysis. Pulmonary tuberculosis is one of the most common infectious diseases worldwide. Patients with suspected pulmonary tuberculosis with negative smear are recommended to undergo further tests including sputum induction and bronchoscopy. Our study is aimed to compare sputum induction and bronchoscopic specimens in the diagnosis of sputum smear-negative

2020 BMC pulmonary medicine

119. Correction: Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. Full Text available with Trip Pro

Correction: Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. [This corrects the article DOI: 10.2196/19930.].©Mohammad Nazmus Sakib, Zahid A Butt, Plinio Pelegrini Morita, Mark Oremus, Geoffrey T Fong, Peter A Hall. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 22.06.2020.

2020 Journal of medical Internet research

120. An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review. Full Text available with Trip Pro

An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review. In the past decade, Lynn Etheredge presented a vision for the Learning Health System (LHS) as an opportunity for increasing the value of health care via rapid learning from data and immediate translation to practice and policy. An LHS is defined in the literature as a system that seeks to continuously generate and apply evidence, innovation, quality, and value in health care.This review aimed to examine

2020 Journal of medical Internet research

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