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81. Does an integrated information technology system provide support for community pharmacists undertaking Discharge Medicines Reviews? An exploratory study Full Text available with Trip Pro

Does an integrated information technology system provide support for community pharmacists undertaking Discharge Medicines Reviews? An exploratory study The aim of this study was to explore the views of community pharmacists participating in the pilot of a secure online platform in Wales, the Choose Pharmacy application (CPA), with particular interest in the electronic Discharge Advice Letters (e-DALs) and online Discharge Medicines Review (DMR) form.A qualitative approach with semi-structured

2017 Integrated pharmacy research & practice

82. Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature Full Text available with Trip Pro

Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature Cardiovascular manifestations in patients with systemic lupus erythematosus (SLE) are common, but aortic aneurysm formation is rare. We present a 63-year-old male SLE patient with a two-year history of skin lesions, leucopenia, pericarditis, mitral valve vegetations consistent with Liebman-Sacks endocarditis, and an aneurysm of the ascending aorta, which was successfully repaired surgically

2017 European journal of rheumatology

83. Health policy and systems research: towards a better understanding and review of ethical issues Full Text available with Trip Pro

Health policy and systems research: towards a better understanding and review of ethical issues Given the focus on health systems in the post-millennium development goal era and moving towards the sustainable development goals, there is a compelling need for a common framework for health policy and systems research ethics to guide researchers and facilitate review by research ethics committees. A consultation of global health policy and systems research and ethics experts was convened (...) to identify ethical considerations relevant to health policy and systems research based on existing knowledge and to identify knowledge gaps through a scoping review and further expert deliberation. Health policy and systems research is highly complex and, in the absence of guidance documents, there is significant variability in ethics review. Although fundamental ethical principles pertain to both traditional clinical research and health policy and systems research, the application of these principles

2017 BMJ global health

84. Epidemiology of burn injuries in Nepal: a systemic review Full Text available with Trip Pro

Epidemiology of burn injuries in Nepal: a systemic review Burn is a global public health problem associated with significant morbidity and mortality, mostly in low- and middle-income countries. Southeast-Asian countries share a big burden of burn injuries, and Nepal is not an exception. We performed a systemic review to examine the epidemiological characteristics of burn injures in Nepal. Relevant epidemiological studies were identified through systemic search in PubMed, EMBASE, and Google (...) Scholar. Reference lists from relevant review articles were also searched. Studies were included if they meet our selection criteria. Eight studies were included in our systemic review. Most of the burn victims belong to the working age group between 15-60 years old. Flame burns were found to be the most common cause of burn injury followed by scald burns, whereas scald burns were the most common cause of burn injury among the pediatric population. Most patients sustained less severe burn injuries

2017 Burns & trauma

85. Three cases of localized cutaneous nodular amyloidosis in patients with limited systemic sclerosis and a brief literature review Full Text available with Trip Pro

Three cases of localized cutaneous nodular amyloidosis in patients with limited systemic sclerosis and a brief literature review Localized cutaneous nodular amyloidosis (LCNA) is the rarest form of localized cutaneous amyloidosis. In patients with LCNA, local plasma cells secrete immunoglobulin light chains called amyloid L via an unknown mechanism. LCNA has been associated with autoimmune connective tissue diseases such as most commonly Sjögren syndrome. A few reported cases of LCNA (...) are associated with limited systemic sclerosis (LSSc). We report three cases of LCNA in patients with LSSc to add to the existing literature, discuss the disease association and proposed pathophysiology, and briefly review the existing information in current literature. It is important to closely follow patients with LCNA to monitor progression to systemic amyloidosis.

2017 International journal of women's dermatology

86. Prostate Imaging Reporting and Data System Version 2 (PI-RADS v2): A pictorial review Full Text available with Trip Pro

Prostate Imaging Reporting and Data System Version 2 (PI-RADS v2): A pictorial review The most recent edition of the prostate imaging reporting and data system (PI-RADS version 2) was developed based on expert consensus of the international working group on prostate cancer. It provides the minimum acceptable technical standards for MR image acquisition and suggests a structured method for multiparametric prostate MRI (mpMRI) reporting. T1-weighted, T2-weighted (T2W), diffusion-weighted (DWI (...) ), and dynamic contrast-enhanced (DCE) imaging are the suggested sequences to include in mpMRI. The PI-RADS version 2 scoring system enables the reader to assess and rate all focal lesions detected at mpMRI to determine the likelihood of a clinically significant cancer. According to PI-RADS v2, a lesion with a Gleason score ≥7, volume >0.5 cc, or extraprostatic extension is considered clinically significant. PI-RADS v2 uses the concept of a dominant MR sequence based on zonal location of the lesion rather

2017 Abdominal radiology (New York)

87. Timeliness of notification systems for infectious diseases: A systematic literature review. Full Text available with Trip Pro

Timeliness of notification systems for infectious diseases: A systematic literature review. Timely notification of infectious diseases is crucial for prompt response by public health services. Adequate notification systems facilitate timely notification. A systematic literature review was performed to assess outcomes of studies on notification timeliness and to determine which aspects of notification systems are associated with timely notification.Articles reviewing timeliness of notifications (...) published between 2000 and 2017 were searched in Pubmed and Scopus. Using a standardized notification chain, timeliness of reporting system for each article was defined as either sufficient (≥ 80% notifications in time), partly sufficient (≥ 50-80%), or insufficient (< 50%) according to the article's predefined timeframe, a standardized timeframe for all articles, and a disease specific timeframe. Electronic notification systems were compared with conventional methods (postal mail, fax, telephone, email

2018 PLoS ONE

89. Examining the Role of Coaching in Health-system Transformations

, selection, assessment, synthesis or presentation of the research evidence profiled in the rapid synthesis. Merit review The rapid synthesis was reviewed by a small number of policymakers, stakeholders and researchers in order to ensure its scientific rigour and system relevance. Acknowledgments The authors wish to thank Chloe Gao for her help in reviewing the literature for this synthesis. We are especially grateful to William Hogg and Sudah Kutty for their insightful comments and suggestions. Citation (...) ; 4) drafting the rapid synthesis in such a way as to present concisely and in accessible language the research evidence; and 5) finalizing the rapid synthesis based on the input of at least two merit reviewers. McMaster Health Forum 5 Evidence >> Insight >> Action implementation coaching infrastructure for these OHTs, we have undertaken a rapid synthesis about the role of coaching in implementing health-system reforms. WHAT WE FOUND We found three systematic reviews and 14 primary studies

2020 McMaster Health Forum

90. Portable Normothermic Cardiac Perfusion System in Donation After Cardiocirculatory Death

. The statements, conclusions, and views expressed in this report do not necessarily represent the views of those we consulted. Citation Ontario Health (Quality). Portable normothermic cardiac perfusion system in donation after cardiocirculatory death: a health technology assessment. Ont Health Technol Assess Ser [Internet]. 2020 Mar;20(3): 1–90. Available from: https://www.hqontario.ca/Evidence-to-Improve-Care/Health- Technology-Assessment/Reviews-And-Recommendations/Portable-Normothermic-Cardiac-Perfusion (...) normothermic cardiac perfusion system for the preservation and transportation of DCD hearts for adult transplantation. This included an evaluation of the effectiveness, safety, value for money, and budget impact of publicly funding this system, as well as an evaluation of patient preferences and values. Methods We performed a systematic review of the clinical literature published since 1998 that examined the clinical safety and effectiveness of a portable normothermic cardiac perfusion system for DCD heart

2020 Health Quality Ontario

91. Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma after 2 or more systemic therapies

of the commercial arrangement. Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma after 2 or more systemic therapies (TA559) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 313 3 Committee discussion Committee discussion The appraisal committee (section 5) considered evidence submitted by Kite Pharma and a review of this submission by the evidence review group (...) Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma after 2 or more systemic therapies Axicabtagene ciloleucel for treating Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and diffuse large B-cell lymphoma and primary mediastinal large B-cell primary mediastinal large B-cell lymphoma after 2 or more systemic lymphoma after 2 or more systemic ther therapies apies T echnology appraisal guidance Published: 23 January

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

92. Tisagenlecleucel for treating relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies

or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies (TA567) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 6 of 253 3 Committee discussion Committee discussion The appraisal committee (section 5) considered evidence submitted by Novartis and a review of this submission by the evidence review group (ERG). See the committee papers for full details of the evidence. New treatment option (...) Tisagenlecleucel for treating relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies Tisagenlecleucel for treating relapsed or Tisagenlecleucel for treating relapsed or refr refractory diffuse large B-cell lymphoma actory diffuse large B-cell lymphoma after 2 or more systemic ther after 2 or more systemic therapies apies T echnology appraisal guidance Published: 13 March 2019 nice.org.uk/guidance/ta567 © NICE 2019. All rights reserved. Subject to Notice

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

93. Covid-19: Countertop Ultraviolet Systems for Disinfecting Mobile Devices

: Searched all available literature through October 2, 2019. We reviewed full text of 2 studies reporting on 64 mobile devices. - 1 prospective, single-center nonrandomized comparison study (14 devices) compared the D6000 UV-C tabletop portable disinfection system to no disinfection in an elderly care ward and a gastroenterology surgery ward and reported on bacterial contamination of the devices. - 1 prospective, single-center before-and-after study (50 devices) compared bacterial contamination before (...) countertop UV systems used to disinfect mobile devices in a clinical setting. We excluded studies of UV lamps and handheld UV devices, studies with fewer than 10 mobile devices, case reports, laboratory studies, and conference abstracts. We also identified a systematic review published in 2019 (literature searches to July 2017) that examined the clinical literature on microbial contamination of computer devices used in healthcare settings and the effectiveness of decontamination methods for these devices

2020 Covid-19 Ad hoc papers

94. Rapid Expert Consultation on Data Elements and Systems Design for Modeling and Decision Making for the COVID-19 Pandemic

University Medical Center, Sandro Galea, Boston University, and Isaac Kohane, Harvard Medical School, reviewed this document, and Ellen Wright Clayton, Vanderbilt University, approved the document as monitor on behalf of the Report Review Committee. Should you desire more substantive and detailed recommendations on system design and content, we would be happy to take this up over a suitable time frame. My colleagues and I hope this input is helpful to you as you continue to guide the nation’s response (...) Rapid Expert Consultation on Data Elements and Systems Design for Modeling and Decision Making for the COVID-19 Pandemic Rapid Expert Consultation | Rapid Expert Consultation on Data Elements and Systems Design for Modeling and Decision Making for the COVID-19 Pandemic (March 21, 2020) | The National Academies Press (2020) Chapter: Rapid Expert Consultation Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading

2020 Covid-19 Ad hoc papers

95. COVID-19 and the cardiovascular system Full Text available with Trip Pro

COVID-19 and the cardiovascular system COVID-19 and the cardiovascular system | Nature Reviews Cardiology Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. A Nature Research Journal COVID-19 and the cardiovascular (...) system , , , , & ( 2020 ) 340k Accesses 8 Citations 1996 Altmetric Subjects Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through ACE2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, while also causing acute myocardial injury and chronic damage to the cardiovascular system. Therefore, particular attention should be given to cardiovascular protection during treatment for COVID-19. In December 2019, an outbreak of pneumonia caused by a novel

2020 Covid-19 Ad hoc papers

96. Covid-19: Hand Hygiene Compliance Monitoring Systems for Reducing Healthcare-associated Infections

Covid-19: Hand Hygiene Compliance Monitoring Systems for Reducing Healthcare-associated Infections CLINICAL EVIDENCE ASSESSMENT © August 2018 ECRI Lytbot Pulsed Xenon UV System (Solaris) for Environmental Disinfection The Lytbot Pulsed Xenon UV System is an ultraviolet (UV) radiation disinfection system that uses 254 nm ultraviolet-C (UVC) light delivered in a “high frequency bulb flash rate” in three-minute cycles, according to the manufacturer. The device also has a reflector system intended (...) to amplify the light energy reaching surfaces. The manufacturer asserts the device can destroy organisms on surfaces at a distance of 10 feet. This report focuses on the safety and efficacy of Lytbot for environmental disinfection. The Evidence Bar™ Evidence is inconclusive — no evidence available Share Your Feedback on how this report answered your question by visiting ly.ecri.org/rate CLINICAL EVIDENCE ASSESSMENT Lytbot Pulsed Xenon UV System (Solaris) for Environmental Disinfection © August 2018 ECRI

2020 Covid-19 Ad hoc papers

97. What clinical features or scoring system, if any, might best predict a benefit from hospital admission for patients with COVID-19?

, as they are derived from a Chinese population in unclear clinical settings, the findings may be of limited applicability to a UK, primary care setting. Guidelines Four guidelines highlight different but overlapping clinical features that may correlate with worse outcomes, sometimes in the context of considering which patients may require hospital-based care [6-9]. None of these guidelines discuss use of a tool or scoring system. It is not within the scope of this review to formally appraise these guidelines (...) What clinical features or scoring system, if any, might best predict a benefit from hospital admission for patients with COVID-19? What clinical features or scoring system, if any, might best predict a benefit from hospital admission for patients with COVID-19? - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website What clinical features or scoring system, if any, might best predict a benefit from hospital

2020 Oxford COVID-19 Evidence Service

98. COVID-19 and Food Safety: Guidance for competent authorities responsible for national food safety control systems

COVID-19 and Food Safety: Guidance for competent authorities responsible for national food safety control systems -1- COVID-19 and Food Safety: Guidance for competent authorities responsible for national food safety control systems Interim guidance 22 April 2020 Background The ongoing COVID-19 pandemic presents an exceptional and unprecedented challenge for competent authorities a with responsibilities for national food safety control systems b to continue conducting routine functions (...) chain, sampling and analysis of food, managing food incidents, providing advice on food safety and food regulations for the food industry, and communicating on food safety issues with the public. To preserve the integrity of the national food safety control system and to support international trade and the food supply chain, each competent authority will need to prioritize critically important services during the ongoing COVID-19 pandemic. These may include introducing temporary suspensions of low

2020 WHO Coronavirus disease (COVID-19) Pandemic

99. Local alcohol services and systems improvement tool

Local alcohol services and systems improvement tool Local alcohol services and systems improvement tool - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Local alcohol services and systems improvement tool Guidance and tools to help plan and improve local alcohol systems, services and interventions to reduce alcohol harm, using the CLeaR approach. Published 1 June 2017 Last updated 19 August 2019 — From (...) : Documents Ref: PHE publications gateway number: GW-619 HTML If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Details CLeaR (Challenge services, Leadership, and Results) is an evidence-based approach to system improvement, which can help to prevent and reduce alcohol-related harm at a local level. This guidance

2020 Public Health England

100. Should temperature screening by thermal imaging systems be part of the policy response to curb COVID-19 transmission?

Government. A rapid review of existing guidance and current evidence was undertaken, with the findings summarised in this report. HIS Evidence Conclusion: The evidence on whether screening by thermal imaging systems is effective in controlling infectious disease transmission is weak or inconclusive at best. The most recent review suggested that screening alone or alongside a questionnaire was not effective at detecting infected persons. The evidence on implementation and impact of screening during (...) Should temperature screening by thermal imaging systems be part of the policy response to curb COVID-19 transmission? A Should temperature screening by thermal imaging systems be part of the policy response to curb Covid- 19 transmission? HIS Evidence were asked to examine whether mass screening by thermal imaging systems should feature in local and national strategies being implemented to control Covid-19 transmission. This is to support the work of Public Health Scotland and the Scottish

2020 Covid-19 Ad hoc papers

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