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61. Systemic Infection Caused by Malassezia pachydermatis in Infants: Case Series and Review of the Literature. (Abstract)

Systemic Infection Caused by Malassezia pachydermatis in Infants: Case Series and Review of the Literature. Malassezia pachydermatis is a rare cause of systemic infection in infants.A total of 4 cases of M. pachydermatis fungemia that occurred in our neonatal intensive care unit over a 21-month period were reviewed, as well as 27 cases reported in the literature since 1988.The patients were preterm with multiple complications and had birth weights ranging from 490 to 810 g and gestational age (...) between 23 and 26 weeks. All patients had received prophylactic fluconazole, broad-spectrum antibiotics and parenteral lipid supplements before fungemia onset, which occurred between the age of 7 and 28 days. Symptoms were nonspecific and thrombocytopenia was the primary laboratory finding. All patients received intravenous antifungal treatment and recovered from their infection. The 27 cases from review of the literature also indicated that the infected infants were extremely low birth weight (77.8

2020 Pediatric Infectious Dsease Journal

62. Comparison of sputum induction and bronchoscopy in diagnosis of sputum smear-negative pulmonary tuberculosis: a systemic review and meta-analysis. Full Text available with Trip Pro

Comparison of sputum induction and bronchoscopy in diagnosis of sputum smear-negative pulmonary tuberculosis: a systemic review and meta-analysis. Pulmonary tuberculosis is one of the most common infectious diseases worldwide. Patients with suspected pulmonary tuberculosis with negative smear are recommended to undergo further tests including sputum induction and bronchoscopy. Our study is aimed to compare sputum induction and bronchoscopic specimens in the diagnosis of sputum smear-negative

2020 BMC pulmonary medicine

63. An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review. Full Text available with Trip Pro

An Analysis of the Learning Health System in Its First Decade in Practice: Scoping Review. In the past decade, Lynn Etheredge presented a vision for the Learning Health System (LHS) as an opportunity for increasing the value of health care via rapid learning from data and immediate translation to practice and policy. An LHS is defined in the literature as a system that seeks to continuously generate and apply evidence, innovation, quality, and value in health care.This review aimed to examine

2020 Journal of medical Internet research

64. Correlating the Bethesda System for Reporting Thyroid Cytopathology with Histology and Extent of Surgery: A Review of 21,746 Patients from Four Endocrine Surgery Registries Across Two Continents. (Abstract)

Correlating the Bethesda System for Reporting Thyroid Cytopathology with Histology and Extent of Surgery: A Review of 21,746 Patients from Four Endocrine Surgery Registries Across Two Continents. The Bethesda system for cytopathology (TBSRTC) is a 6-tier diagnostic framework developed to standardize thyroid cytopathology reporting. The aim of this study was to determine the risk of malignancy (ROM) for each Bethesda category.Thyroidectomy-related data from 314 facilities in 22 countries were

2020 World Journal of Surgery

65. Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. Full Text available with Trip Pro

Considerations for an Individual-Level Population Notification System for Pandemic Response: A Review and Prototype. The outbreak of the coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, spread worldwide after its emergence in China. Whether rich or poor, all nations are struggling to cope with this new global health crisis. The speed of the threat's emergence and the quick response required from public health authorities and the public itself makes (...) evident the need for a major reform in pandemic surveillance and notification systems. The development and implementation of a graded, individual-level pandemic notification system could be an effective tool to combat future threats of epidemics. This paper describes a prototype model of such a notification system and its potential advantages and challenges for implementation. Similar to other emergency alerts, this system would include a number of threat levels (level 1-5) with a higher level

2020 Journal of medical Internet research

66. Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: a systemic review and meta-analysis. (Abstract)

Laparoendoscopic rendezvous versus ERCP followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: a systemic review and meta-analysis. The ideal management for patients with cholecystocholedocholithiasis is still controversial. Laparoendoscopic rendezvous (LERV), combined with laparoscopy and endoscopy, is a novel and attractive technique. The aim of this research was to compare LERV with traditional two-stage management, preoperative ERCP and laparoscopic

2020 Surgical endoscopy

67. Requirements of Health Data Management Systems for Biomedical Care and Research: Scoping Review. Full Text available with Trip Pro

Requirements of Health Data Management Systems for Biomedical Care and Research: Scoping Review. Over the last century, disruptive incidents in clinical and biomedical research fields have yielded a tremendous change in the health data management system. This is due to the breakthrough in the medical field and the need for big data analytics and the Internet of Things (IoT) to be incorporated in a real-time smart health information management system. In addition, the requirements of patient (...) ) medical record data, (2) real-time data access, (3) patient participation, (4) data sharing, (5) data security, (6) patient identity privacy, and (7) public insights. This paper reviews the health data management systems based on these 7 requirements across studies conducted over the years. To our knowledge, this is the first analysis of the temporal evolution of health data management systems giving insights on the system requirements for better health care.There is a need for a comprehensive real

2020 Journal of medical Internet research

68. Nailfold Videocapillaroscopy in Systemic Sclerosis-related Pulmonary Arterial Hypertension: A Systematic Literature Review. (Abstract)

Nailfold Videocapillaroscopy in Systemic Sclerosis-related Pulmonary Arterial Hypertension: A Systematic Literature Review. Pulmonary arterial hypertension (PAH) is one of the leading causes of death in systemic sclerosis (SSc). Current screening algorithms are hampered by low positive predictive values. Outcome measures that could add to performance characteristics would be welcome. We aim to evaluate the role of nailfold videocapillaroscopy (NVC) using standardized definitions, in SSc-related (...) PAH (SSc-PAH).A systematic review to identify original research papers documenting an association between NVC and right heart catheterization-defined SSc-PAH was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Subsequently, NVC characteristics were subdivided into quantitative (capillary density, dimension, morphology, and hemorrhages), semiquantitative, and qualitative assessment (NVC pattern), according to the definitions

2020 Journal of Rheumatology

69. Dermatological manifestations of Epstein-Barr virus systemic infection: a case report and literature review. (Abstract)

Dermatological manifestations of Epstein-Barr virus systemic infection: a case report and literature review. Epstein-Barr virus (EBV) is a human herpesvirus spread in childhood by contact with saliva. In all populations, the great majority of people are infected by middle age. EBV can cause asymptomatic infection, nonspecific symptoms or, especially in adolescents and young adults, the infectious mononucleosis (IM), characterized by pharyngitis, lymphadenopathy, fatigue, and fever. Two main (...) of atypical exanthem with an erythematous-papulovesicular pattern in a 22-year-old female patient with IM and performed a review of the literature of the cutaneous and mucosal eruptions occurring during EBV acute infections.© 2020 the International Society of Dermatology.

2020 International Journal of Dermatology

70. Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week. Full Text available with Trip Pro

Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week. Severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II receptor (...) with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld.Copyright © 2020. Published by Elsevier Inc.

2020 Journal of the American College of Cardiology

71. Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis

Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study (...) , O'Connor RJ, Phillips M, Ramdharry G. Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis. Health Technology Assessment 2016; 20(55) Authors' objectives To assess existing evidence on the effectiveness of orthoses; patient perspectives; types of orthotic devices prescribed in the UK NHS; and associated costs. Patients who have knee instability that is associated with neuromuscular

2016 Health Technology Assessment (HTA) Database.

72. Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development. Full Text available with Trip Pro

Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development. Pharmacogenomic clinical decision support systems (CDSS) have the potential to help overcome some of the barriers for translating pharmacogenomic knowledge into clinical routine. Before developing a prototype it is crucial for developers to know which pharmacogenomic CDSS features and user-system interactions have (...) yet been developed, implemented and tested in previous pharmacogenomic CDSS efforts and if they have been successfully applied. We address this issue by providing an overview of the designs of user-system interactions of recently developed pharmacogenomic CDSS.We searched PubMed for pharmacogenomic CDSS published between January 1, 2012 and November 15, 2016. Thirty-two out of 118 identified articles were summarized and included in the final analysis. We then compared the designs of user-system

2017 Medical Informatics and Decision Making

73. Evaluation of the skills, knowledge and experience required by nurses and pharmacists in multi-professional systemic anti-cancer therapy review clinics: a systematic review

Evaluation of the skills, knowledge and experience required by nurses and pharmacists in multi-professional systemic anti-cancer therapy review clinics: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening: As above, with the addition of: 7. No relevant outcome measure reported ">Prioritise the exclusion criteria Example: Two reviewers will independently extract data from each article. We first try to extract numerical data from tables, text or figures. If these are not reported, we

2020 PROSPERO

74. Identifying Leading Indicators of System Resilience and the Strategy for Developing Them: A Review of Reviews

Identifying Leading Indicators of System Resilience and the Strategy for Developing Them: A Review of Reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) : Example: Screening will be performed in two phases, namely initial screening based on title and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3

2020 PROSPERO

75. Update of Screening, Diagnosis and Staging of Breast cancer: Review of Cohort study, RCT , Systemic Review and Clinical Guideline

Update of Screening, Diagnosis and Staging of Breast cancer: Review of Cohort study, RCT , Systemic Review and Clinical Guideline Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record (...) criteria: Exclusion criteria: Example: Screening will be performed in two phases, namely initial screening based on title and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2

2020 PROSPERO

76. The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation

The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation Picot J, Copley V, Colquitt JL, Kalita N, Hartwell D, Bryant J Record Status (...) This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Picot J, Copley V, Colquitt JL, Kalita N, Hartwell D, Bryant J. The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation. Health Technology Assessment 2015; 19(69) Authors' objectives To assess the clinical effectiveness and cost-effectiveness

2015 Health Technology Assessment (HTA) Database.

77. superDimension Navigation System to help diagnostic sampling of peripheral lung lesions

unquantifiable instances of multiple-counting of patients in the systematic reviews. T able 2 summarises the clinical evidence as well as its strengths and limitations. Overall assessment of the evidence The body of evidence for superDimension Navigation System is large, with several systematic reviews and meta-analyses including a large number of primary studies and thousands of patients worldwide, although none in a UK setting. Primary outcomes include diagnostic yield and safety parameters (...) . (2018) superDimension Navigation System to help diagnostic sampling of peripheral lung lesions (MIB194) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 7 of 17Study size, design and location Systematic review with limited meta-analysis (search dates January 2000 to November 2017). n=1,648 ENB cases from 31 selected studies. China. Intervention and comparator(s) ENB biopsy of lesion in lung parenchyma and mediastinal

2019 National Institute for Health and Clinical Excellence - Advice

78. Prevena incision management system for closed surgical incisions

Prevena incision management system for closed surgical incisions Pre Prev vena incision management system for closed ena incision management system for closed surgical incisions surgical incisions Medtech innovation briefing Published: 28 February 2019 www.nice.org.uk/guidance/mib173 pathways Summary Summary The technology technology described in this briefing is Prevena. It is a single-use technology for the management of closed surgical incisions that may be at increased risk of infection (...) #notice-of-rights). Page 1 of 12considered in this briefing. The technology The technology Prevena (Kinetic Concepts Inc. an Acelity Company) is a wound management system that is placed over a closed surgical incision. The device applies continuous negative pressure. This helps promote healing by holding the incision edges together, drawing fluid and exudate out of the wound, reducing oedema and stimulating perfusion. The device is single use and can stay in place for up to 7 days. Prevena

2019 National Institute for Health and Clinical Excellence - Advice

79. Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer - state of knowledge

Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer - state of knowledge 1 Translation of the executive summary of the rapid report Biomarkerbasierte Tests zur Entscheidung für oder gegen eine adjuvante systemische Chemotherapie beim primären Mammakarzinom – Aktualisierung zum Auftrag D14-01 (Version 1.1; Status: 26 February 2020). Please note: This translation is provided as a service by IQWiG to English-language readers. However (...) , solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. D19-01 Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer – update to Commission D14-01 1 Extract of rapid report D19-01 Version 1.1 Biomarkers in breast cancer 26 February 2020 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency

2020 Institute for Quality and Efficiency in Healthcare (IQWiG)

80. The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system

as an ERCP session. One specialist commentator also noted that in his experience of working in a specialist unit, patients can be selected to have ERCP with the SpyGlass as a first-line procedure after the clinicians have reviewed their MRI or CT scan findings. One specialist commentator stated that the SpyGlass is currently used in The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system (MIB21) © NICE 2018. All rights reserved. Subject (...) The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system The Sp The SpyGlass direct visualisation system for yGlass direct visualisation system for diagnostic and ther diagnostic and therapeutic procedures during apeutic procedures during endoscop endoscopy of the biliary system y of the biliary system Medtech innovation briefing Published: 12 February 2015 nice.org.uk/guidance/mib21 pathways Summary Summary The SpyGlass system

2015 National Institute for Health and Clinical Excellence - Advice

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