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Review of Systems

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281. A Review and Update of Treatment Options Using the Acne Scar Classification System. (Abstract)

A Review and Update of Treatment Options Using the Acne Scar Classification System. An unfortunate consequence of acne vulgaris is residual scarring that can negatively affect a patient's quality of life.Jacob and colleagues have previously described an acne scar classification system based on acne scar pathology that divided atrophic acne scars into icepick, rolling, and boxcar scars, and this review will evaluate new and developing treatment options for acne scarring.A Medline search (...) was performed on the various treatments for acne scars, and particular attention was placed on articles that used the acne scar classification system of icepick, rolling, and boxcar scars.Therapies for acne scarring included surgical modalities, such as subcision, and punch excision and elevation, injectable fillers, chemical peels, dermabrasion, microneedling, and energy-based devices. In the past decade, there has been a trend toward using cosmetic fillers and energy-based devices to improve acne

2019 Dermatologic Surgery

282. Review article: the role of the autonomic nervous system in the pathogenesis and therapy of IBD. Full Text available with Trip Pro

Review article: the role of the autonomic nervous system in the pathogenesis and therapy of IBD. There is a growing body of evidence implicating a role for the brain-gut axis in the pathogenesis of inflammation in patients with IBD.To perform a narrative review of published literature regarding the association of the autonomic nervous system and intestinal inflammation and to describe the rationale for and emerging use of autonomic manipulation as a therapeutic agent METHODS: Current relevant (...) literature was summarised and critically examined.There is substantial pre-clinical and clinical evidence for a multifaceted anti-inflammatory effect of the vagus at both systemic and local intestinal levels. It acts via acetylcholine-mediated activation of α-7-acetylcholine receptors involving multiple cell types in innate and adaptive immunity and the enteric nervous system with subsequent protective influences on the intestinal barrier, inflammatory mechanisms and the microbiome. In patients with IBD

2019 Alimentary Pharmacology & Therapeutics

283. Classification of patients with cold sensation by a review of systems database: A single-centre observational study. (Abstract)

Classification of patients with cold sensation by a review of systems database: A single-centre observational study. In Kampo medicine, a traditional medicine pattern(TM1) refers to the complete clinical presentation of the patient at a given moment in time. Candidate herbal formulas are chosen for a chief complaint, and an appropriate formula is determined on the basis of the pattern(TM1) diagnosis. In this study, we demonstrated the importance of accompanying symptoms in diagnosing (...) traditional medicine patterns(TM1).Single centre observational study.We analysed data from 524 new patients with a hypersensitivity to cold sensation as their primary diagnosis (mean age 51.6 ± 17.8 years; female ratio 82.1%) who visited the Keio University Hospital Kampo Clinic between 2008 and 2013.Accompanying symptoms were recorded on the browser-based e-questionnaire system, which contained 128 items. The Japan Society for Oriental Medicine's board certified Kampo specialists diagnosed

2019 Complementary Therapies In Medicine

284. A review of measurement practice in studies of clinical decision support systems 1998-2017. Full Text available with Trip Pro

A review of measurement practice in studies of clinical decision support systems 1998-2017. To assess measurement practice in clinical decision support evaluation studies.We identified empirical studies evaluating clinical decision support systems published from 1998 to 2017. We reviewed titles, abstracts, and full paper contents for evidence of attention to measurement validity, reliability, or reuse. We used Friedman and Wyatt's typology to categorize the studies.There were 391 studies (...) in problem impact studies with the majority of measures being clinical or patient reported outcomes with validity measured elsewhere.Measurement methodology is frequently ignored in empirical studies of clinical decision support systems and particularly so in field user effect studies. Authors may in fact be attending to measurement considerations and not reporting this or employing methods of unknown validity and reliability in their studies. In the latter case, reported study results may be biased

2019 Journal of the American Medical Informatics Association

285. Herb induced liver injury after using herbal medicine: A systemic review and case-control study. Full Text available with Trip Pro

Herb induced liver injury after using herbal medicine: A systemic review and case-control study. In Taiwan, traditional herbal medication was included in Taiwan's National Health Insurance (NHI) system since 1996 and in 9 out of 10 hospitals have developed their own departments of traditional medicine. This study aims to address the herb-induced liver injury (HILI) after using herbal medicine on the relationship between age, gender, epidemiology, laboratory data, pathogenesis, mobility (...) , and mortality.We searched the PubMed database with "hepatitis after herbal medicine" and "in human" till 2018 April and returned 163 articles in a systemic review manner. Two cases reports describing in-vitro liver injury were excluded. Reviews and articles without the detailed report, laboratory data and history were excluded from this study. In the end, there were 53 articles enrolled in this study. These enrolled literatures are from France (n = 13), Germany (n = 12), Switzerland (n = 5) United States

2019 Medicine

286. Implementing advance care planning with community-dwelling frail elders requires a system-wide approach: An integrative review applying a behaviour change model. Full Text available with Trip Pro

Implementing advance care planning with community-dwelling frail elders requires a system-wide approach: An integrative review applying a behaviour change model. Facilitating advance care planning with community-dwelling frail elders can be challenging. Notably, frail elders' vulnerability to sudden deterioration leads to uncertainty in recognising the timing and focus of advance care planning conversations.To understand how advance care planning can be better implemented for community-dwelling (...) frail elders and to develop a conceptual model to underpin intervention development.A structured integrative review of relevant literature.CINAHL, Embase, Ovid Medline, PsycINFO, Cochrane Library, and University of York Centre for Reviews and Dissemination. Further strategies included searching for policy and clinical documents, grey literature, and hand-searching reference lists. Literature was searched from 1990 until October 2018.From 3043 potential papers, 42 were included. Twenty-nine were

2019 Palliative medicine

287. The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol. Full Text available with Trip Pro

The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol. Low back pain is the greatest contributor to the global burden of disease and can result in work disability. Previous literature has examined the influence of personal factors, the healthcare system, workplace, and income support systems on work disability due to low back pain. Income support systems may also influence healthcare and the workplace, leading (...) to an impact on healthcare quality and functional capacity. However, there has been little insight as to how or in what contexts this influence occurs. This realist review aims to provide an explanation of how and in what contexts income support systems impact the healthcare quality and functional capacity of people who are unable to work due to low back pain.Realist reviews are a type of literature review that seek to determine how and in what contexts a social programme such as income support leads

2019 Systematic reviews

288. Understanding patient engagement in health system decision-making: a co-designed scoping review. Full Text available with Trip Pro

Understanding patient engagement in health system decision-making: a co-designed scoping review. With healthcare striving to shift to a more person-centered delivery model, patient and family involvement must have a bigger role in shaping this. While many initiatives involving patients and family members focus on self-care, a broader understanding of patient participation is necessary. Ensuring a viable and sustainable critical number of qualified patients and family members to support (...) this shift will be of utmost importance. The purpose of this study was to understand how health systems are intentionally investing in the training and skill development of patients and family members.Patient co-investigators and researchers conducted a scoping review of the existing literature on methods adopted by healthcare systems to build the skills and capacity of patients to participate in healthcare decision-making using a recognized methodological framework. Six electronic databases were

2019 Systematic reviews

289. Systemic therapy in cervical cancer: 30 years in review. (Abstract)

Systemic therapy in cervical cancer: 30 years in review. Advanced-inoperable cervical cancer is a challenging entity due to increased percentage of locoregional and distant recurrences. Furthermore, recurrent cervical cancer not amenable to radical treatment as well as de novo metastatic disease are considered incurable with dismal prognosis. Well-designed clinical trials conducted during the last 30 years have revealed the active chemotherapeutic agents as well as their optimal combinations

2019 Critical reviews in oncology/hematology

290. Optimising paediatric afferent component early warning systems: a hermeneutic systematic literature review and model development. Full Text available with Trip Pro

Optimising paediatric afferent component early warning systems: a hermeneutic systematic literature review and model development. To identify the core components of successful early warning systems for detecting and initiating action in response to clinical deterioration in paediatric inpatients.A hermeneutic systematic literature review informed by translational mobilisation theory and normalisation process theory was used to synthesise 82 studies of paediatric and adult early warning systems (...) in isolation. While it was not possible to make empirical recommendations for practice, the review methodology generated theoretical inferences about the core components of an optimal system for early warning systems. These are presented as a propositional model conceptualised as three subsystems: detection, planning and action.There is a growing consensus of the need to think beyond TTTs in improving action to detect and respond to clinical deterioration. Clinical teams wishing to improve early warning

2019 BMJ open

291. Quality of patient, family, caregiver and public engagement in decision-making in healthcare systems: a scoping review protocol. Full Text available with Trip Pro

Quality of patient, family, caregiver and public engagement in decision-making in healthcare systems: a scoping review protocol. To advance person- and family-centred healthcare, government initiatives have supported the engagement of patients and family caregivers in decision-making in healthcare systems. There is, however, no consensus on how to define success for such initiatives. This scoping review aims to identify the key elements for defining the quality of patient and family caregiver (...) engagement in decision-making across the engagement domains (individual, community/organisation, system) of British Columbia's healthcare system. We will use those elements to develop a conceptual evaluation framework.This scoping review follows Arskey and O'Malley's methodology. (1) The research question was identified through team discussions. (2) Articles for data source will be identified using a librarian-informed search strategy for seven bibliographic databases as well as grey literature sources

2019 BMJ open

292. Information and Communication Systems to Tackle Barriers to Breastfeeding: Systematic Search and Review. Full Text available with Trip Pro

Information and Communication Systems to Tackle Barriers to Breastfeeding: Systematic Search and Review. Breastfeeding has many benefits for newborns, mothers, and the wider society. The World Health Organization recommends mothers to feed newborns exclusively with breastmilk for the first 6 months after birth, but breastfeeding rates in many countries fail to align with the recommendations because of various barriers. Breastfeeding success is associated with a number of determinants (...) and the perspective of end users.The objective of this review was to provide a comprehensive overview of existing digital interventions that support breastfeeding by investigating systems' objective, technology design, validation process, and quality attributes, both in terms of clinical parameters as well as usability and user experience.A systematic search was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines in the following libraries: PubMed, Science

2019 Journal of medical Internet research

293. Early warning system models and components in emergency and disaster: a systematic literature review protocol. Full Text available with Trip Pro

Early warning system models and components in emergency and disaster: a systematic literature review protocol. Emergency and disaster are on the rise in the world. One of the most important components of disaster risk management is the early warning system. Studies have shown divergent models of warning systems with different structures. However, since no systematic review of early warning systems in disasters has been conducted so far, a systematic review of the models, components (...) , and structures of these systems is essential. This protocol is a systematic review study, which aims to evaluate the existing warning systems and their structure.This study attempts to comprehensively search the previous studies with terms and expressions including disaster, emergency model, early warning system, and their synonyms at MESH. To this end, English articles, which have been published from 1980 to 2019, will be assessed. Google Scholar, PubMed, Web of Science, and Scopus databases as well

2019 Systematic reviews

294. Are there decision support tools that might strengthen the health system for perinatal care in South African district hospitals? A review of the literature. Full Text available with Trip Pro

Are there decision support tools that might strengthen the health system for perinatal care in South African district hospitals? A review of the literature. South Africa has a high burden of perinatal deaths in spite of the availability of evidence-based interventions. The majority of preventable perinatal deaths occur in district hospitals and are mainly related to the functioning of the health system. Particularly, leadership in district hospitals needs to be strengthened in order to decrease (...) the burden of perinatal mortality. Decision-making is a key function of leaders, however leaders in district hospitals are not supported to make evidence-based decisions. The aim of this research was to identify health system decision support tools that can be applied at district hospital level to strengthen decision-making in the health system for perinatal care in South Africa.A structured approach, the systematic quantitative literature review method, was conducted to find published articles

2019 BMC health services research

295. Detection and classification of systemic sclerosis-related interstitial lung disease: a review. (Abstract)

Detection and classification of systemic sclerosis-related interstitial lung disease: a review. Systemic sclerosis (SSc) is a heterogeneous disease with a variable disease course. Interstitial lung disease (ILD) is one of the leading causes of morbidity and mortality in patients with SSc. The present review highlights recent advances in the classification, diagnosis, and early detection of SSc-associated ILD (SSc-ILD).Risk stratification through measurement of disease extent on high-resolution

2019 Current Opinion in Rheumatology

296. What makes health systems resilient against infectious disease outbreaks and natural hazards? Results from a scoping review. Full Text available with Trip Pro

What makes health systems resilient against infectious disease outbreaks and natural hazards? Results from a scoping review. The 2014-2016 Ebola outbreak was a wake-up call regarding the critical importance of resilient health systems. Fragile health systems can become overwhelmed during public health crises, further exacerbating the human, economic, and political toll. Important work has been done to describe the general attributes of a health system resilient to these crises, and the next (...) step will be to identify the specific capacities that health systems need to develop and maintain to achieve resiliency.We conducted a scoping review of the literature to identify recurring themes and capacities needed for health system resiliency to infectious disease outbreaks and natural hazards and any existing implementation frameworks that highlight these capacities. We also sought to identify the overlap of the identified themes and capacities with those highlighted in the World Health

2019 BMC Public Health

297. Multiple food-borne trematodiases with profound systemic involvement: a case report and literature review. (Abstract)

Multiple food-borne trematodiases with profound systemic involvement: a case report and literature review.

2019 BMC Infectious Diseases

298. Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis. (Abstract)

Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis.

2019 BMC Infectious Diseases

299. Systemic Pharmacologic Therapies for Low Back Pain: A Systematic Review for an American College of Physicians Clinical Practice Guideline. (Abstract)

Systemic Pharmacologic Therapies for Low Back Pain: A Systematic Review for an American College of Physicians Clinical Practice Guideline. A 2007 American College of Physicians guideline addressed pharmacologic options for low back pain. New evidence and medications have now become available.To review the current evidence on systemic pharmacologic therapies for acute or chronic nonradicular or radicular low back pain.Ovid MEDLINE (January 2008 through November 2016), Cochrane Central Register (...) of Controlled Trials, Cochrane Database of Systematic Reviews, and reference lists.Randomized trials that reported pain, function, or harms of systemic medications versus placebo or another intervention.One investigator abstracted data, and a second verified accuracy; 2 investigators independently assessed study quality.The number of trials ranged from 9 (benzodiazepines) to 70 (nonsteroidal anti-inflammatory drugs). New evidence found that acetaminophen was ineffective for acute low back pain, nonsteroidal

2017 Annals of Internal Medicine

300. Hepatitis B Virus Reactivation Associated With Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus: A Review of Cases Reported to the U.S. Food and Drug Administration Adverse Event Reporting System. (Abstract)

Hepatitis B Virus Reactivation Associated With Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus: A Review of Cases Reported to the U.S. Food and Drug Administration Adverse Event Reporting System. Direct-acting antiviral agents (DAAs) are used increasingly to treat hepatitis C virus (HCV) infection. Reports were published recently on hepatitis B virus (HBV) reactivation (HBV-R) in patients with HBV-HCV co-infection. Hepatitis B virus reactivation, defined as an abrupt increase (...) in HBV replication in patients with inactive or resolved HBV infection, may result in clinically significant hepatitis.To assess whether HBV-R is a safety concern in patients receiving HCV DAAs.Descriptive case series.U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS).29 patients with HBV-R receiving HCV DAAs.Clinical and laboratory data.The FDA identified 29 unique reports of HBV-R in patients receiving DAAs from 22 November 2013 to 15 October 2016. Two cases resulted

2017 Annals of Internal Medicine

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