How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

129,173 results for

Review of Systems

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma: A systematic review. (Abstract)

Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma: A systematic review. Cutaneous melanoma is typically treated with wide local excision and, when appropriate, a sentinel node biopsy. Many patients are cured with this approach but for patients who have cancers with high risk features there is a significant risk of local and distant relapse and death. Interferon-based adjuvant therapy was recommended in the past but had modest results with significant toxicity (...) . Recently, new therapies (immune checkpoint inhibitors and targeted therapies) have been found to be effective in the treatment of patients with metastatic melanoma and many of these therapies have been evaluated and found to be effective in the adjuvant treatment of high risk patients with melanoma. This systematic review of adjuvant therapies for cutaneous and mucosal melanoma was conducted for Ontario Health (Cancer Care Ontario) as the basis of a clinical practice guideline to address the question

2020 Cancer Treatment Reviews

182. Hyperthermic intraperitoneal chemotherapy combined with systemic chemotherapy for gastric cancer peritoneal carcinomatosis: A protocol for systematic review and meta-analysis of randomized controlled trials. Full Text available with Trip Pro

Hyperthermic intraperitoneal chemotherapy combined with systemic chemotherapy for gastric cancer peritoneal carcinomatosis: A protocol for systematic review and meta-analysis of randomized controlled trials. The prognosis of gastric cancer peritoneal carcinomatosis (GCPC) remains poor despite recent advances in systemic chemotherapy (SC) with an average survival less than 6 months. Current evidence supporting the utility of hyperthermic intraperitoneal chemotherapy (HIPEC) combined with SC (...) , and if necessary, a subgroup analysis will be performed to explore the source of heterogeneity.The results will provide useful information about the effectiveness and safety of HIPEC combined with systemic chemotherapy regimens in patients with gastric cancer peritoneal carcinomatosis.The findings of the study will be disseminated through peer-reviewed journal.INPLASY202050006.10.37766/inplasy2020.5.0006.

2020 Medicine

183. The efficacy and safety of fecal microbiota transplantation in the treatment of systemic sclerosis: A protocol for systematic review and meta analysis. Full Text available with Trip Pro

The efficacy and safety of fecal microbiota transplantation in the treatment of systemic sclerosis: A protocol for systematic review and meta analysis. Systemic sclerosis (SSc) is 1 of the most complex systemic autoimmune diseases.Accumulating evidence suggests that gut microbiota affect the development and function of the immune system and may play a role in the pathogenesis of autoimmune diseases. This new paradigm raises the possibility that many diseases result, at least partially, from (...) of Science,Cochrane Central Register of Controlled Trials (CENTRAL) Cochrane Library, EMBASE and China National Knowledge Infrastructure. We will apply a combination of Medical Subject Heading (MeSH) and free-text terms incorporating database-specific controlled vocabularies and text words to implement search strategies. We will also search the ongoing trials registered in the World Health Organization's International Clinical Trials Registry Platform. Besides, the previous relevant reviews conducted

2020 Medicine

184. Inflammatory cytokine levels in multiple system atrophy: A protocol for systematic review and meta-analysis. Full Text available with Trip Pro

Inflammatory cytokine levels in multiple system atrophy: A protocol for systematic review and meta-analysis. Multiple system atrophy (MSA) is a fatal neurodegenerative disease that progresses very rapidly and has a poor prognosis. Some studies indicate that the level of inflammatory cytokines may be related to MSA. However, no consistent conclusion has been drawn yet. The purpose of our research is to perform a meta-analysis to investigate whether the level of inflammatory cytokines is altered (...) in MSA.Case-control studies on inflammatory cytokine levels in MSA will be searched in the following 3 databases: PubMed, Embase, and Web of Science from the database start time to March 17, 2020. Two independent authors will conduct research selection, data extraction, and quality evaluation. Data synthesis, subgroup analysis, sensitivity analysis, and the meta-analysis will be performed using Stata15.0 software.This study will provide a comprehensive review of all studies on inflammatory cytokine levels

2020 Medicine

185. Brentuximab vedotin in combination for untreated systemic anaplastic large cell lymphoma

Brentuximab vedotin in combination for untreated systemic anaplastic large cell lymphoma Brentuximab vedotin in combination for untreated systemic anaplastic large cell lymphoma T echnology appraisal guidance Published: 12 August 2020 www.nice.org.uk/guidance/ta641 © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Your responsibility Your responsibility The recommendations in this guidance represent the view of NICE (...) . Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Brentuximab vedotin in combination for untreated systemic anaplastic large cell lymphoma (TA641) © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 15Contents Contents 1 Recommendations 4 2

2020 National Institute for Health and Clinical Excellence - Technology Appraisals

186. Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis

Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study (...) , O'Connor RJ, Phillips M, Ramdharry G. Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis. Health Technology Assessment 2016; 20(55) Authors' objectives To assess existing evidence on the effectiveness of orthoses; patient perspectives; types of orthotic devices prescribed in the UK NHS; and associated costs. Patients who have knee instability that is associated with neuromuscular

2016 Health Technology Assessment (HTA) Database.

187. Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development. Full Text available with Trip Pro

Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development. Pharmacogenomic clinical decision support systems (CDSS) have the potential to help overcome some of the barriers for translating pharmacogenomic knowledge into clinical routine. Before developing a prototype it is crucial for developers to know which pharmacogenomic CDSS features and user-system interactions have (...) yet been developed, implemented and tested in previous pharmacogenomic CDSS efforts and if they have been successfully applied. We address this issue by providing an overview of the designs of user-system interactions of recently developed pharmacogenomic CDSS.We searched PubMed for pharmacogenomic CDSS published between January 1, 2012 and November 15, 2016. Thirty-two out of 118 identified articles were summarized and included in the final analysis. We then compared the designs of user-system

2017 Medical Informatics and Decision Making

188. Environmental and genetic risk factors and cardiovascular diseases for patients with systemic lupus erythematosus: an umbrella review of systematic reviews and meta-analyses

Environmental and genetic risk factors and cardiovascular diseases for patients with systemic lupus erythematosus: an umbrella review of systematic reviews and meta-analyses Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) -abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening: As above, with the addition of: 7. No relevant outcome measure reported ">Prioritise the exclusion criteria Example: Two reviewers will independently extract data from each article. We first try to extract numerical data from

2020 PROSPERO

189. Identifying Leading Indicators of System Resilience and the Strategy for Developing Them: A Review of Reviews

Identifying Leading Indicators of System Resilience and the Strategy for Developing Them: A Review of Reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) : Example: Screening will be performed in two phases, namely initial screening based on title and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3

2020 PROSPERO

190. Update of Screening, Diagnosis and Staging of Breast cancer: Review of Cohort study, RCT , Systemic Review and Clinical Guideline

Update of Screening, Diagnosis and Staging of Breast cancer: Review of Cohort study, RCT , Systemic Review and Clinical Guideline Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record (...) criteria: Exclusion criteria: Example: Screening will be performed in two phases, namely initial screening based on title and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2

2020 PROSPERO

191. Evaluation of the skills, knowledge and experience required by nurses and pharmacists in multi-professional systemic anti-cancer therapy review clinics: a systematic review

Evaluation of the skills, knowledge and experience required by nurses and pharmacists in multi-professional systemic anti-cancer therapy review clinics: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening: As above, with the addition of: 7. No relevant outcome measure reported ">Prioritise the exclusion criteria Example: Two reviewers will independently extract data from each article. We first try to extract numerical data from tables, text or figures. If these are not reported, we

2020 PROSPERO

192. The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation

The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation Picot J, Copley V, Colquitt JL, Kalita N, Hartwell D, Bryant J Record Status (...) This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Picot J, Copley V, Colquitt JL, Kalita N, Hartwell D, Bryant J. The INTRABEAM® Photon Radiotherapy System for the adjuvant treatment of early breast cancer: a systematic review and economic evaluation. Health Technology Assessment 2015; 19(69) Authors' objectives To assess the clinical effectiveness and cost-effectiveness

2015 Health Technology Assessment (HTA) Database.

193. superDimension Navigation System to help diagnostic sampling of peripheral lung lesions

unquantifiable instances of multiple-counting of patients in the systematic reviews. T able 2 summarises the clinical evidence as well as its strengths and limitations. Overall assessment of the evidence The body of evidence for superDimension Navigation System is large, with several systematic reviews and meta-analyses including a large number of primary studies and thousands of patients worldwide, although none in a UK setting. Primary outcomes include diagnostic yield and safety parameters (...) . (2018) superDimension Navigation System to help diagnostic sampling of peripheral lung lesions (MIB194) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 7 of 17Study size, design and location Systematic review with limited meta-analysis (search dates January 2000 to November 2017). n=1,648 ENB cases from 31 selected studies. China. Intervention and comparator(s) ENB biopsy of lesion in lung parenchyma and mediastinal

2019 National Institute for Health and Clinical Excellence - Advice

194. Prevena incision management system for closed surgical incisions

Prevena incision management system for closed surgical incisions Pre Prev vena incision management system for closed ena incision management system for closed surgical incisions surgical incisions Medtech innovation briefing Published: 28 February 2019 www.nice.org.uk/guidance/mib173 pathways Summary Summary The technology technology described in this briefing is Prevena. It is a single-use technology for the management of closed surgical incisions that may be at increased risk of infection (...) #notice-of-rights). Page 1 of 12considered in this briefing. The technology The technology Prevena (Kinetic Concepts Inc. an Acelity Company) is a wound management system that is placed over a closed surgical incision. The device applies continuous negative pressure. This helps promote healing by holding the incision edges together, drawing fluid and exudate out of the wound, reducing oedema and stimulating perfusion. The device is single use and can stay in place for up to 7 days. Prevena

2019 National Institute for Health and Clinical Excellence - Advice

195. Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer - state of knowledge

Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer - state of knowledge 1 Translation of the executive summary of the rapid report Biomarkerbasierte Tests zur Entscheidung für oder gegen eine adjuvante systemische Chemotherapie beim primären Mammakarzinom – Aktualisierung zum Auftrag D14-01 (Version 1.1; Status: 26 February 2020). Please note: This translation is provided as a service by IQWiG to English-language readers. However (...) , solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. D19-01 Biomarker-based tests to support the decision for or against adjuvant systemic chemotherapy in primary breast cancer – update to Commission D14-01 1 Extract of rapid report D19-01 Version 1.1 Biomarkers in breast cancer 26 February 2020 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency

2020 Institute for Quality and Efficiency in Healthcare (IQWiG)

196. Systemic treatments for eczema: a network meta-analysis. (Abstract)

Systemic treatments for eczema: a network meta-analysis. Eczema is a common and chronic, relapsing, inflammatory skin disorder. It seriously impacts quality of life and economic outcomes, especially for those with moderate to severe eczema. Various treatments allow sustained control of the disease; however, their relative benefit remains unclear due to the limited number of trials directly comparing treatments.To assess the comparative efficacy and safety of different types of systemic (...) immunosuppressive treatments for moderate to severe eczema using NMA and to generate rankings of available systemic immunosuppressive treatments for eczema according to their efficacy and safety.We searched the following databases up to August 2019: the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, and Embase.All randomised controlled trials (RCTs) of systemic immunosuppressive agents for moderate to severe atopic eczema when compared against placebo or any other eligible eczema treatment.We synthesised

2020 Cochrane

197. Levonorgestrel-releasing intrauterine system for endometrial hyperplasia. (Abstract)

Levonorgestrel-releasing intrauterine system for endometrial hyperplasia. In the absence of treatment, endometrial hyperplasia (EH) can progress to endometrial cancer, particularly in the presence of histologic nuclear atypia. The development of EH results from exposure of the endometrium to oestrogen unopposed by progesterone. Oral progestogens have been used as treatment for EH without atypia, and in some cases of EH with atypia in women who wish to preserve fertility or who cannot tolerate (...) surgery. EH without atypia is associated with a low risk of progression to atypia and cancer; EH with atypia is where the cells are structurally abnormal, and has a higher risk of developing cancer. Oral progestogen is not always effective at reversing the hyperplasia, can be associated with side effects, and depends on patient adherence. The levonorgestrel-intrauterine system (LNG-IUS) is an alternative method of administration of progestogen and may have some advantages over non-intrauterine

2020 Cochrane

198. Patient-initiated appointment systems for adults with chronic conditions in secondary care. (Abstract)

status or disease activity (including harms), quality of life, service utilisation or cost, adverse effects, patient or clinician satisfaction, or failures of the 'system'.Two review authors independently screened all references at title/abstract stage and full-text stage using prespecified inclusion criteria. We resolved disagreements though discussion. Two review authors independently completed data extraction for all included studies. We discussed and resolved discrepancies with a third review (...) Patient-initiated appointment systems for adults with chronic conditions in secondary care. Missed hospital outpatient appointments is a commonly reported problem in healthcare services around the world; for example, they cost the National Health Service (NHS) in the UK millions of pounds every year and can cause operation and scheduling difficulties worldwide. In 2002, the World Health Organization (WHO) published a report highlighting the need for a model of care that more readily meets

2020 Cochrane

199. The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system

as an ERCP session. One specialist commentator also noted that in his experience of working in a specialist unit, patients can be selected to have ERCP with the SpyGlass as a first-line procedure after the clinicians have reviewed their MRI or CT scan findings. One specialist commentator stated that the SpyGlass is currently used in The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system (MIB21) © NICE 2018. All rights reserved. Subject (...) The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system The Sp The SpyGlass direct visualisation system for yGlass direct visualisation system for diagnostic and ther diagnostic and therapeutic procedures during apeutic procedures during endoscop endoscopy of the biliary system y of the biliary system Medtech innovation briefing Published: 12 February 2015 nice.org.uk/guidance/mib21 pathways Summary Summary The SpyGlass system

2015 National Institute for Health and Clinical Excellence - Advice

200. Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 7: Antibiotic-impregnated shunt systems versus conventional shunts in children: a systematic review and meta-analysis

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 7: Antibiotic-impregnated shunt systems versus conventional shunts in children: a systematic review and meta-analysis J Neurosurg: Pediatrics / Volume 14 / November 2014 J Neurosurg Pediatrics (Suppl) 14:53–59, 2014 53 ©AANS, 2014 P revention of shunt infection is a priority for neu- rosurgeons, especially when treating pediatric pa- tients. Infection can cause shunt malfunction with all the potential (...) factors or inter - ventions to lower the risk of a shunt infection has been the topic of active research for many years. Identified factors include the duration of surgery; 32,41 the skill and experi- ence of the treating neurosurgeon; 7,10,29 the number of per- sonnel in the operating room; 9,30,39 and the use of hair shav- ing, 25,41 prophylactic systemic antibiotics, 22,42,56 intrathecal Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 7: Antibiotic

2014 Congress of Neurological Surgeons

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>