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181. Glucocorticoids in systemic sclerosis: weighing up the benefits and risks ? a systematic review

Glucocorticoids in systemic sclerosis: weighing up the benefits and risks ? a systematic review Glucocorticoids in systemic sclerosis: weighing up the benefits and risks – a systematic review Glucocorticoids in systemic sclerosis: weighing up the benefits and risks – a systematic review Iudici M, van der Goes MC, Valentini G, Bijlsma JW CRD summary The review concluded that evidence of a beneficial effect of glucocorticoids in patients with systemic sclerosis was limited. Despite some concerns (...) about the review process, the limited quality of the included studies and the inability to distinguish the effects of glucocorticoids alone, the authors' conclusion seems reasonable. Authors' objectives To evaluate the efficacy and safety of glucocorticoids in patients with systemic sclerosis. Searching PubMed, EMBASE, and The Cochrane Library were searched up to October 2012 for English language articles. Search terms were reported. Reference lists of included studies were screened. Study selection

2013 DARE.

182. Knee Implant Systems: A Review of the Comparative Clinical Effectiveness

Knee Implant Systems: A Review of the Comparative Clinical Effectiveness TITLE: Knee Implant Systems: A Review of the Comparative Clinical Effectiveness DATE: 21 October 2013 CONTEXT AND POLICY ISSUES Knee osteoarthritis (OA) is a clinical syndrome in which the cartilage of the joint is worn out by progressive breakdown and destruction. 1 In 2010, more than 9.9 million adults in the USA had symptomatic osteoarthritis of the knee. 2 Nonoperative therapies can be effective in mild cases; however (...) . The objective of this review is to evaluate the effectiveness of the implant systems used for the unicompartmental knee arthroplasty. RESEARCH QUESTIONS OrthoGlide Minimally Invasive Surgery 1. What is the evidence for the clinical effectiveness of OrthoGlide implants? 2. What is the clinical evidence regarding the adverse events and failures of OrthoGlide implants? Patello-Femoral Joint Implants 3. What is the evidence for the clinical effectiveness of patello-femoral joint implants? 4. What

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

183. Effects of renin-angiotensin system blockades on cardiovascular outcomes in patients with diabetes mellitus: a systematic review and meta-analysis

Effects of renin-angiotensin system blockades on cardiovascular outcomes in patients with diabetes mellitus: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

184. A rigorous review of the political economy of education systems in developing countries

A rigorous review of the political economy of education systems in developing countries A rigorous review of the political economy of education systems in developing countries 06 April 2019 Links Download report (pdf) A rigorous review of the political economy of education systems in developing countries What do we want to know? This review pulls together essential literature from various disciplinary and interdisciplinary traditions and provides a conceptual framework to analyse political (...) on the political economy of education systems in developing countries to enable advisors and Ministers to formulate policies based on causal linkages supported by strong evidence. It aimed to: (i) review existing evidence on the review topic to inform programme design and policy making undertaken by the DfID, other agencies and researchers; and (ii) identify critical evidence gaps to guide the development of future research programmes. What did we find? Some stakeholder groups (e.g. teachers compared

2014 EPPI Centre

185. Systemic therapy with immunosuppressive agents and retinoids in hidradenitis suppurativa: a systematic review

Systemic therapy with immunosuppressive agents and retinoids in hidradenitis suppurativa: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

186. Computerized decision support systems in primary care for type 2 diabetes patients only improve patients' outcomes when combined with feedback on performance and case management: a systematic review

Computerized decision support systems in primary care for type 2 diabetes patients only improve patients' outcomes when combined with feedback on performance and case management: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

187. Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review

Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review de Brito Poveda V, Martinez EZ, Galvao CM CRD summary This review concluded that, compared with forced-air warming, circulating water garments were more effective in maintaining the temperature of patients during surgery (...) ; carbon-fibre systems were as effective as forced air. The trials were generally small and of low quality and there were flaws in the search and review processes. The conclusions should be treated with caution. Authors' objectives To assess the effectiveness of different active cutaneous warming systems to prevent hypothermia during surgery. Searching MEDLINE, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were searched for articles from 2000 to August 2010. Search terms

2013 DARE.

188. Comparative efficacy and safety of long-acting insulin analogs in patients with type 2 diabetes failing on oral therapy: systemic [systematic] review and meta-analyses

Comparative efficacy and safety of long-acting insulin analogs in patients with type 2 diabetes failing on oral therapy: systemic [systematic] review and meta-analyses Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

189. Beneficial effect of real-time continuous glucose monitoring system on glycemic control in type 1 diabetic patients: systematic review and meta-analysis of randomized trials

Beneficial effect of real-time continuous glucose monitoring system on glycemic control in type 1 diabetic patients: systematic review and meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

190. Mental health of adults in contact with the criminal justice system

learning disabilities), cognitive impairments, or physical health problems or disabilities. Seek advice or involve specialists if needed. 1.3 Identification and assessment throughout the care pathway 1.3.1 Be vigilant for the possibility of unidentified or emerging mental health problems in people in contact with the criminal justice system, and review available records for any indications of a mental health problem. 1.3.2 Ensure all staff working in criminal justice settings are aware of the potential (...) ) community meeting for all wing residents daily (5 days only) social activity groups for all wing residents a once-weekly individual review meeting (20 minutes). 1.6.11 Consider psychological interventions for paraphilias only when delivered as part of a research programme. 1.7 Pharmacological interventions 1.7.1 Refer to relevant NICE guidance for pharmacological interventions for mental health problems in adults in contact with the criminal justice system. T ake into account: risks associated

2017 National Institute for Health and Clinical Excellence - Clinical Guidelines

191. Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness

Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness | CADTH.ca Find the information you need Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness Last updated: September 6, 2019 Project Number: RC1175-000 Product Line: Research Type: Devices and Systems (...) population.One economic evaluation was identified that suggested there was a net benefit to the Spanish national health system when pharmacists carried out medication review with follow-up among patients 65 years or older taking 5 or more medications. Differences in the healthcare delivery models and unit costs between Spain and Canada should be considered when generalizing results for the Canadian context. Files Rapid Response Summary with Critical Appraisal Published : September 6, 2019 Follow us: © 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

192. Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines

-Effectiveness and Guidelines Last updated: August 20, 2019 Project Number: RC1171-000 - CI0058-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical utility of multidisciplinary medication review every three months in long-term care settings? What is the cost-effectiveness of multidisciplinary medication review every three months in long-term care settings? What are the evidence-based guidelines regarding the use (...) Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness and Guidelines Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

193. Impact of financial inclusion in low? and middle?income countries: A systematic review of reviews Full Text available with Trip Pro

Impact of financial inclusion in low? and middle?income countries: A systematic review of reviews Impact of financial inclusion in low‐ and middle‐income countries: A systematic review of reviews - Duvendack - 2019 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Impact of financial inclusion in low‐ and middle‐income countries (...) : A systematic review of reviews Corresponding Author E-mail address: School of International Development, University of East Anglia, Norwich, NR4 7TJ UK Correspondence Maren Duvendack, University of East Anglia, School of International Development, Norwich Research Park, Norwich NR4 7TJ, UK. Email: Philip Mader, Institute of Development Studies, Library Road, University of Sussex, Brighton, East Sussex BN19RE, UK. Email: Corresponding Author E-mail address: Institute of Development Studies, University

2019 Campbell Collaboration

194. Therapeutic Communities for Adults in the Correctional System: Clinical Effectiveness, Cost Effectiveness, and Guidelines

therapeutic communities for reducing recidivism or substance abuse in adults within the correctional system? Key Message One health technology assessments, eleven systematic reviews (six with meta-analyses), one overview of systematic reviews with a meta-analysis, five randomized controlled trials, seven non-randomized trials, one economic evaluation, and one evidence-based guideline were identified regarding therapeutic communities for adults in the correctional system. Files Rapid Response Summary (...) Therapeutic Communities for Adults in the Correctional System: Clinical Effectiveness, Cost Effectiveness, and Guidelines Therapeutic Communities for Adults in the Correctional System: Clinical Effectiveness, Cost Effectiveness, and Guidelines | CADTH.ca Find the information you need Therapeutic Communities for Adults in the Correctional System: Clinical Effectiveness, Cost Effectiveness, and Guidelines Therapeutic Communities for Adults in the Correctional System: Clinical Effectiveness, Cost

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

195. Systemic Adjuvant Therapy for Adult Patients at High Risk for Recurrent Melanoma

G, McWhirter E, Rajagopal S, Song X, Wright F. Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma. Toronto (ON): Cancer Care Ontario; 2019 Aug 14. Program in Evidence-Based Care Guideline No.: 8-1 version 5. PUBLICATIONS RELATED TO THIS REPORT Petrella T, Verma S, Spithoff K, Quirt I, McCready D; Melanoma Disease Site Group. Adjuvant interferon therapy for patients at high risk for recurrent melanoma: An updated systematic review and practice guideline. Clin Oncol (...) (R Coll Radiol). 2012 Aug;24(6):413-23. Verma S, Quirt I, McCready D, Bak K, Charette M, Iscoe N; on behalf of the Melanoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care. Systematic review of systemic adjuvant therapy for patients at high risk for recurrent melanoma. Cancer. 2006;106(7):1431-42. Verma S, Quirt I, McCready D, Charette M, Iscoe N; Melanoma Disease Site Group. Systemic adjuvant therapy for patients at high risk for recurrent melanoma. Curr Oncol. 2005;12

2019 Cancer Care Ontario

196. Systemic Therapy for Advanced or Recurrent Endometrial Cancer and Advanced or Recurrent Uterine Papillary Serous Carcinoma

://www.cancercare.on.ca/ or contact the PEBC office at: Phone: 905-527-4322 ext. 42822 Fax: 905-526-6775 E-mail: ccopgi@mcmaster.ca PEBC Report Citation (Vancouver Style): Gawlik C, Carey M, Faught W, Fung Kee Fung M, Chambers A; Members of the Gynecology Cancer Disease Site Group. Systemic therapy for advanced or recurrent endometrial cancer, and advanced or recurrent uterine papillary serous carcinoma. Covens A, Durocher-Allen L, reviewers. Toronto (ON): Cancer Care Ontario; 2004 Aug 17 [Endorsed 2019 Jul 23 (...) ]. Program in Evidence-based Care Practice Guideline Report No.:4-8 Version 4 ENDORSED. Journal Citation (Vancouver Style): Carey MS, Gawlik C, Fung-Kee-Fung M, Chambers A, Oliver T; Cancer Care Ontario Practice Guidelines Initiative Gynecology Cancer Disease Site Group. Systematic review of systemic therapy for advanced or recurrent endometrial cancer. Gynecol Oncol. 2006;101(1):158-67. Guideline Report History GUIDELINE VERSION SYSTEMATIC REVIEW PUBLICATIONS NOTES and KEY CHANGES Search Dates Data

2019 Cancer Care Ontario

197. Belimumab (Benlysta ) - systemic lupus erythematosus

Belimumab (Benlysta ) - systemic lupus erythematosus belimumab | CADTH.ca Find the information you need belimumab belimumab Last Updated: October 1, 2019 Result type: Reports Project Number: SR0616-000 Product Line: Generic Name: Belimumab Brand Name: Benlysta Manufacturer: GlaxoSmithKline Inc. Indications: systemic lupus erythematosus Manufacturer Requested Reimbursement Criteria 1 : For the treatment of SLE patients who meet the following eligibility criteria: Adult patients age 18 years (...) . Reimbursement criteria from CADTH will be documented in the final recommendation, if applicable. Key Milestones 2 Call for patient input posted April 30, 2019 Patient group input closed June 19, 2019 Clarification: - Patient input submission received from The Arthritis Society and Canadian Arthritis Patient Alliance Patient input summary sent for review to patient input groups June 21, 2019 Patient group comments on input summary closed June 28, 2019 Clarification: - Patient input summary feedback received

2019 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

198. Complex surgery and perioperative systemic therapy for genitourinary cancer of the retroperitoneum

of a multidisciplinary case conference. Key Evidence for Recommendation 8 ? Key evidence was derived from three systematic reviews and meta-analyses [18-20] and one randomized trial (conference abstract) [21]. (This study will be fully published later this year [study authors, personal communication]) ? The systematic review and meta-analysis by Gregg et al. investigated systemic treatment in UTUC. Perioperative chemotherapy was associated with an improved OS (HR, 0.75; 95% CI, 0.57 to 0.99; p=0.05; I 2 =57 (...) systematic reviews and an abstract from an RCT were found that pertain to systemic treatment and UTUC. This abstract is the only randomized trial of adjuvant chemotherapy and UTUC. The systematic reviews do not contain randomized trials since they were conducted before the POUT trial was completed. The systematic review and meta- analysis by Gregg et al. investigated systemic treatment in UTUC. There were no randomized trials and all the data came from 11 retrospective studies: seven single institution

2019 Cancer Care Ontario

199. Preparing Emerging Leaders for Alternative Futures in Health Systems Across Canada

. Merit review The evidence brief was reviewed by a small number of policymakers, stakeholders and researchers in order to ensure its scientific rigour and system relevance. Acknowledgments We are grateful to the 26 key informants who were interviewed to help with the iterative development of the list of expected futures (which later came to be called ‘alternative futures’), and to the 19 key informants who were interviewed to provide feedback on the terms of reference for this evidence brief. We wish (...) on incremental change rather than anticipating or stewarding alternative futures; and o health-system arrangements are not aligned to support the identification, development or cultivation of emerging leaders. What do we know (from systematic reviews) about three elements of a potentially comprehensive approach to addressing the problem? • Element 1 – Establish a collective vision for how emerging leaders need to be prepared for alternative futures o This element could include two sub-elements: 1

2019 McMaster Health Forum

200. Supporting Rapid Learning and Improvement Across Ontario’s Health System

the problem? • There are several interrelated factors that underpin the need to support rapid learning and improvement across Ontario’s health system: o there is (and always will be) room for improvement in the health system; o despite the many assets in Ontario’s health and research systems, many gaps remain; and o there are opportunities to better connect assets in Ontario and leverage pan-Canadian assets. What do we know (from systematic reviews) about three elements of a potentially comprehensive (...) review examined attempts to adopt the rapid-learning health-system paradigm, with an emphasis on implementation and evaluating the impact on current medical practices, and found minimal focus on evaluating impacts on healthcare delivery and patient outcomes. What implementation considerations need to be kept in mind • While many barriers to implementing these elements may exist at the level of patients, providers, organizations and systems, perhaps the biggest barrier lies in achieving agreement

2019 McMaster Health Forum

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