How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

188 results for

Retrobulbar Optic Neuropathy

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Acute Effect of Hypervolemic Hemodilution on Retrobulbar Hemodynamics in Anterior Ischemic Optic Neuropathy (PubMed)

Acute Effect of Hypervolemic Hemodilution on Retrobulbar Hemodynamics in Anterior Ischemic Optic Neuropathy Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ischemic optic neuropathy (NAION).24 patients with acute NAION were included (...) 2.16 ± 0.56 to 2.34 ± 0.55  (p < 0.05)) and in the PCAs (PSV from 7.18 ± 1.62 to 7.56 ± 1.55  (p < 0.01); EDV from 2.48 ± 0.55 to 2.66 ± 0.6 cm/sec (p < 0.01)). The RI of all retrobulbar vessels remained unaffected. Blood pressure and heart rate remained unchanged.Hypervolemic hemodilution has an acute effect on blood flow velocities in the CRA and PCAs in NAION patients. Increased blood flow in the arteries supplying the optic nerve head may lead to a better perfusion in NAION patients. This trial

Full Text available with Trip Pro

2018 BioMed research international

2. Macular ganglion cell complex measurement in bilateral retrobulbar optic neuropathy without a relative afferent pupillary defect (PubMed)

Macular ganglion cell complex measurement in bilateral retrobulbar optic neuropathy without a relative afferent pupillary defect This study aimed to demonstrate the clinical usefulness of measuring the macular ganglion cell complex (GCC) for the early detection of axonal loss in eyes with bilateral retrobulbar optic neuropathies.We retrospectively reviewed the medical records of three patients with bilateral toxic, ischemic, or infiltrative retrobulbar optic neuropathy.No relative afferent (...) optic disks still appeared normal.A reduction in the macular GCC thickness seemed to precede the appearance of optic disk pallor and occurs regardless of toxic, ischemic, or infiltrative retrobulbar optic neuropathy. The current case series suggested that measurement of the macular GCC facilitated early differentiation between bilateral retrobulbar optic neuropathy and nonorganic visual loss, which can otherwise be challenging in some cases.

Full Text available with Trip Pro

2018 International medical case reports journal

3. Retrobulbar optic neuropathy associated with sphenoid sinus mucormycosis (PubMed)

Retrobulbar optic neuropathy associated with sphenoid sinus mucormycosis Because fungi usually spread from the paranasal sinuses to the orbital apex in invasive fungal sinusitis (IFS), IFS often presents as an orbital apex syndrome (OAS) characterized by dysfunction of cranial nerves II, III, IV, V1, and VI. We report a case of sphenoid sinus mucormycosis that presented as isolated retrobulbar optic neuropathy. A 94-year-old woman presented with acute blindness in the right eye. Examination (...) revealed the absence of light perception and pupillary reflex in the right eye. Head MRI showed a mass in the right sphenoid sinus, which was contiguous with the right optic nerve. She underwent endoscopic surgery, and a histopathological diagnosis of mucormycosis was established. Treatment with intravenous liposomal amphotericin B reduced the size of the mass. She has survived for more than 1 year without recurrence. Clinicians should consider that IFS can present as isolated retrobulbar optic

Full Text available with Trip Pro

2018 Neurology and clinical neuroscience

4. Retrobulbar Optic Neuropathy

Retrobulbar Optic Neuropathy Retrobulbar Optic Neuropathy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Retrobulbar Optic Neuropathy (...) Retrobulbar Optic Neuropathy Aka: Retrobulbar Optic Neuropathy , Optic Neuritis From Related Chapters II. Causes Encephalomyelitis vascular lesions Tumor glioma Meningioma Fungal infections Medications Aminosalicylic acid Chloramphenicol Phenothiazines Phenylbutazone Quinine III. Associated Conditions IV. Epidemiology Young patients predominate V. Symptoms Pain behind affected eye is variably present Impaired vision develops over hours to days Affects one or both eyes Rarely results in total blindness

2018 FP Notebook

5. The relation between retrobulbar blood flow and posterior ocular changes measured using spectral-domain optical coherence tomography in patients with obstructive sleep apnea syndrome. (PubMed)

The relation between retrobulbar blood flow and posterior ocular changes measured using spectral-domain optical coherence tomography in patients with obstructive sleep apnea syndrome. To investigate the effect of posterior ocular hemodynamics on the retinal nerve fiber layer (RNFL), choroid thickness (CT) and central macular thickness (CMT) in patients with obstructive sleep apnea syndrome (OSAS) and to reveal the association with glaucomatous optic neuropathy.The research was planned (...) values of the PCA, which supplies the optic nerve, show a linear increase as the apnea hypoxia index values in OSAS. As the grade of OSAS improves, this situation leads to a more serious ischemic optic neuropathy. Furthermore, the prevalence of glaucoma in this study is found to be higher in the severe OSAS group.

2018 International ophthalmology

6. Retrobulbar optic neuropathy secondary to isolated sphenoid sinus disease (PubMed)

Retrobulbar optic neuropathy secondary to isolated sphenoid sinus disease Paranasal sinus disease can cause a condition that mimics optic neuritis. Simultaneous appearance of both diseases would create etiological dilemma. We report two cases of retrobulbar optic neuropathy secondary to isolated sphenoid sinus disease. In the case of a 65-year-old female who had presented with acute loss of vision in the left eye associated with left-sided frontal headache which subsequently turned out (...) to be caused by optic nerve compression at the orbital apex due to collection in abnormally pneumatized left lesser wing of the sphenoid. In another case, a 65-year-old lady had presented with symptoms of bilateral retrobulbar optic neuropathy which was found to be due to direct compression of optic nerves at the orbital apex secondary to metastases from breast carcinoma.

Full Text available with Trip Pro

2015 Journal of neurosciences in rural practice

7. Citicoline in Non-Arteritic Ischemic Optic Neuropathy

product Positive history for diseases of the optic nerve (retrobulbar optic neuropathy, glaucoma) or systemic diseases which could preclude the enrolment in the study according to the investigators' judgement Pregnant or nursing women, or women of potential childbearing age not using adequate contraception. Diabetes, SLE, rheumatoid arthritis, mixed connective tissue disease Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your (...) Citicoline in Non-Arteritic Ischemic Optic Neuropathy Citicoline in Non-Arteritic Ischemic Optic Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Citicoline in Non-Arteritic Ischemic Optic

2018 Clinical Trials

8. Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients (PubMed)

Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients Although the current Zika virus (ZIKV) epidemic is a major public health concern, most reports have focused on congenital ZIKV syndrome, its most devastating manifestation. Severe ocular complications associated with ZIKV infections and possible pathogenetic factors are rarely described. Here, we describe three Venezuelan patients who developed severe ocular manifestations following (...) ZIKV infections. We also analyse their serological response to ZIKV and dengue virus (DENV).One adult with bilateral optic neuritis, a child of 4 years of age with retrobulbar uveitis and a newborn with bilateral congenital glaucoma had a recent history of an acute exanthematous infection consistent with ZIKV infection. The results of ELISA tests indicated that all patients were seropositive for ZIKV and four DENV serotypes.Patients with ZIKV infection can develop severe ocular complications. Anti

Full Text available with Trip Pro

2018 JMM Case Reports

9. Optic neuropathy causing vertical unilateral hemianopsia after pars plana vitrectomy for a macular hole: A case report. (PubMed)

to dry-up during air/fluid exchange or retinal neurotoxicity of the dye used to visualize the internal limiting membrane (ILM), as well as unintentional removal of retinal neurofibers during ILM peeling, are responsible for such visual field disorders. In this report, we present a case of extensive visual field defect due to optic neuropathy exhibiting vertical hemianopsia after PPV.A 50-year-old woman underwent PPV and cataract surgery for a macular hole and mild cataract under retrobulbar (...) Optic neuropathy causing vertical unilateral hemianopsia after pars plana vitrectomy for a macular hole: A case report. Recent progress in medical technology has resulted in improved surgical outcomes of pars plana vitrectomy (PPV); with microincision systems, the incidence of procedure-related complications during surgery has been reduced. However, unpredictable visual field defects after PPV remain an unresolved issue. A few reports have shown that damage to the retinal neurofibers owing

Full Text available with Trip Pro

2018 Medicine

10. Stem Cell Ophthalmology Treatment Study: bone marrow derived stem cells in the treatment of non-arteritic ischemic optic neuropathy (NAION) (PubMed)

Stem Cell Ophthalmology Treatment Study: bone marrow derived stem cells in the treatment of non-arteritic ischemic optic neuropathy (NAION) Ten patients with bilateral visual loss due to sequential non-arteritic ischemic optic neuropathy (NAION) underwent autologous Bone Marrow Derived Stem Cell (BMSC) therapy within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical study utilizing autologous BMSC in the treatment of optic nerve (...) and retinal diseases that meet inclusion criteria.The average age of the patients treated was 69.8 years. The average duration of visual loss in eyes treated was 9.8 years and ranged from 1 to 35 years. Affected eyes were treated with either retrobulbar, subtenons and intravenous BMSC or, following vitrectomy, intra-optic nerve, subtenons and intravenous BMSC. The primary outcome was visual acuity as measured by Snellen or converted to LogMAR.Following therapy in SCOTS, 80% of patients experienced

Full Text available with Trip Pro

2017 Stem Cell Investigation

11. Stem Cell Ophthalmology Treatment Study (SCOTS): bone marrow-derived stem cells in the treatment of Leber's hereditary optic neuropathy (PubMed)

Stem Cell Ophthalmology Treatment Study (SCOTS): bone marrow-derived stem cells in the treatment of Leber's hereditary optic neuropathy The Stem Cell Ophthalmology Treatment Study (SCOTS) is currently the largest-scale stem cell ophthalmology trial registered at ClinicalTrials.gov (identifier: NCT01920867). SCOTS utilizes autologous bone marrow-derived stem cells (BMSCs) to treat optic nerve and retinal diseases. Treatment approaches include a combination of retrobulbar, subtenon, intravitreal (...) , intra-optic nerve, subretinal, and intravenous injection of autologous BMSCs according to the nature of the disease, the degree of visual loss, and any risk factors related to the treatments. Patients with Leber's hereditary optic neuropathy had visual acuity gains on the Early Treatment Diabetic Retinopathy Study (ETDRS) of up to 35 letters and Snellen acuity improvements from hand motion to 20/200 and from counting fingers to 20/100. Visual field improvements were noted. Macular and optic nerve

Full Text available with Trip Pro

2016 Neural Regeneration Research

12. Optic neuritis

Optic neuritis Optic neuritis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Optic neuritis Last reviewed: February 2019 Last updated: March 2018 Summary May involve the retrobulbar (retrobulbar neuritis) or the intrabulbar (papillitis) portion of the optic nerve, or both. Idiopathic ON, the most common form of ON, is an inflammatory optic neuropathy in the absence of evidence of a systemic inflammatory disease. May (...) in the treatment of idiopathic acute ON. Definition Optic neuritis (ON) represents inflammation of the optic nerve. By far the most common form is idiopathic ON, which is a primary demyelinating disease occurring in isolation or as part of multiple sclerosis (MS). Ebers GC. Optic neuritis and multiple sclerosis. Arch Neurol. 1985;42:702-704. http://www.ncbi.nlm.nih.gov/pubmed/4015469?tool=bestpractice.com Optic Neuritis Study Group. The clinical profile of optic neuritis: experience of the Optic Neuritis

2018 BMJ Best Practice

13. Retrobulbar Optic Neuropathy

Retrobulbar Optic Neuropathy Retrobulbar Optic Neuropathy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Retrobulbar Optic Neuropathy (...) Retrobulbar Optic Neuropathy Aka: Retrobulbar Optic Neuropathy , Optic Neuritis From Related Chapters II. Causes Encephalomyelitis vascular lesions Tumor glioma Meningioma Fungal infections Medications Aminosalicylic acid Chloramphenicol Phenothiazines Phenylbutazone Quinine III. Associated Conditions IV. Epidemiology Young patients predominate V. Symptoms Pain behind affected eye is variably present Impaired vision develops over hours to days Affects one or both eyes Rarely results in total blindness

2015 FP Notebook

14. Computed Tomographic Angiogram of an Anterior Communicating Artery Aneurysm Causing Acute Retrobulbar Optic Neuropathy: A Case Report (PubMed)

Computed Tomographic Angiogram of an Anterior Communicating Artery Aneurysm Causing Acute Retrobulbar Optic Neuropathy: A Case Report Three-dimensional computed tomographic (3D-CT) angiography is a widespread imaging modality for intracranial vascular lesions. However, 3D-CT angiograms of an anterior communicating artery aneurysm associated with acute retrobulbar optic neuropathy have not been previously described. We present 3D-CT angiograms of an aneurysm of the anterior communicating artery

Full Text available with Trip Pro

2011 Korean journal of ophthalmology : KJO

15. Toxic/Nutritional Optic Neuropathy (Overview)

. . Miller NR. Anterior toxic optic neuropathies. Walsh and Hoyt's Clinical Neuro-Ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 254-260. Miller NR. Retrobulbar toxic and deficiency optic neuropathies. Walsh and Hoyt's Clinical Neuro-ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 289-307. Phillips PH. Toxic and deficiency optic neuropathies. Miller NR, Newman NJ, eds. Walsh and Hoyt's Clinical Neuro-ophthalmology . 6th ed. Baltimore: Lippincott Williams (...) Toxic/Nutritional Optic Neuropathy (Overview) Toxic/Nutritional Optic Neuropathy: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxNzY2MS1vdmVydmlldw== processing

2014 eMedicine.com

16. Toxic/Nutritional Optic Neuropathy (Follow-up)

& Wilkins; 1982. 254-260. Miller NR. Retrobulbar toxic and deficiency optic neuropathies. Walsh and Hoyt's Clinical Neuro-ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 289-307. Phillips PH. Toxic and deficiency optic neuropathies. Miller NR, Newman NJ, eds. Walsh and Hoyt's Clinical Neuro-ophthalmology . 6th ed. Baltimore: Lippincott Williams & Wilkins; 2005. 447-463. Rizzo JF 3rd, Lessell S. Tobacco amblyopia. Am J Ophthalmol . 1993 Jul 15. 116(1):84-7. . Sadun AA. Metabolic (...) Toxic/Nutritional Optic Neuropathy (Follow-up) Toxic/Nutritional Optic Neuropathy Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxNzY2MS10cmVhdG1lbnQ

2014 eMedicine.com

17. Toxic/Nutritional Optic Neuropathy (Treatment)

& Wilkins; 1982. 254-260. Miller NR. Retrobulbar toxic and deficiency optic neuropathies. Walsh and Hoyt's Clinical Neuro-ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 289-307. Phillips PH. Toxic and deficiency optic neuropathies. Miller NR, Newman NJ, eds. Walsh and Hoyt's Clinical Neuro-ophthalmology . 6th ed. Baltimore: Lippincott Williams & Wilkins; 2005. 447-463. Rizzo JF 3rd, Lessell S. Tobacco amblyopia. Am J Ophthalmol . 1993 Jul 15. 116(1):84-7. . Sadun AA. Metabolic (...) Toxic/Nutritional Optic Neuropathy (Treatment) Toxic/Nutritional Optic Neuropathy Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxNzY2MS10cmVhdG1lbnQ

2014 eMedicine.com

18. Toxic/Nutritional Optic Neuropathy (Diagnosis)

. . Miller NR. Anterior toxic optic neuropathies. Walsh and Hoyt's Clinical Neuro-Ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 254-260. Miller NR. Retrobulbar toxic and deficiency optic neuropathies. Walsh and Hoyt's Clinical Neuro-ophthalmology . 4th ed. Baltimore: Lippincott Williams & Wilkins; 1982. 289-307. Phillips PH. Toxic and deficiency optic neuropathies. Miller NR, Newman NJ, eds. Walsh and Hoyt's Clinical Neuro-ophthalmology . 6th ed. Baltimore: Lippincott Williams (...) Toxic/Nutritional Optic Neuropathy (Diagnosis) Toxic/Nutritional Optic Neuropathy: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxNzY2MS1vdmVydmlldw== processing

2014 eMedicine.com

19. Rhinogenic Optic Neuritis Caused by Sphenoid Mucocele with Sinusitis (PubMed)

Rhinogenic Optic Neuritis Caused by Sphenoid Mucocele with Sinusitis A 59-year-old male who presented with a nonspecific headache at the vertex, resembling retrobulbar optic neuritis, was treated as such but did not show any improvement. Although optic nerve compression from sphenoid mucocele was finally discovered, the delayed diagnosis and improper treatment led to a permanent visual loss. Optic neuritis could be caused by a common problem, "mucocele/sinusitis," but might be easily overlooked (...) in general practice. Rhinogenic optic neuropathy should, therefore, be considered in every case of optic neuritis whenever atypical presentation occurs or is unresponsive to high-dose steroid treatment.

Full Text available with Trip Pro

2018 Case Reports in Radiology

20. Retrobulbar Triamcinolone Acetonide Injection in the Treatment of NA-AION

,but have some side effects. the investigators believe that offering them Retrobulbar Triamcinolone Acetonide Injection that might halt the progression of the visual acuity and visual field loss if our hypothesis is correct, would greatly improve their chances of avoiding blindness. Condition or disease Intervention/treatment Phase Triamcinolone Acetonide Optic Neuropathy, Ischemic Drug: Triamcinolone Acetonide Drug: placebo Phase 3 Study Design Go to Layout table for study information Study Type (...) : Interventional (Clinical Trial) Estimated Enrollment : 60 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Official Title: Retrobulbar Triamcinolone Acetonide Injection in the Treatment of Nonarteritic Anterior Ischemic Optic Neuropathy Study Start Date : May 2015 Estimated Primary Completion Date : December 2015 Estimated Study Completion Date : January 2016 Resource links provided by the National Library

2014 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>