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Relaxation Technique

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121. T<sub>1ρ</sub> and T<sub>2</sub> Relaxation Times are Associated with Progression of Hip Osteoarthritis. (PubMed)

T and T2 Relaxation Times are Associated with Progression of Hip Osteoarthritis. To evaluate whether baseline T1ρ and T2 relaxation times of hip cartilage are associated with magnetic resonance imaging (MRI) based progression of hip osteoarthritis (OA) at 18 months.3T MRI studies of the hip were obtained at baseline and 18-month follow-up for 54 subjects without evidence of severe OA at baseline [Kellgren-Lawrence (KL) score of 0-3]. 2D fast spin-echo sequences were used (...) for semi-quantitative morphological scoring of cartilage lesions and a combined T1ρ/T2 sequence was used to quantitatively assess cartilage composition. Progression of hip OA was defined based on incident or progression of morphological semi-quantitative grade at 18 months. Baseline T1ρ and T2 relaxation times were compared between progressors and non-progressors using one-way analysis of variance and Mann-Whitney U tests and used to predict progression with binary logistic regression after adjusting

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2016 Osteoarthritis and Cartilage

122. The effect of peri-implantation administration of uterine relaxing agents in assisted reproduction treatment cycles: a systematic review and meta-analysis. (PubMed)

. This systematic review aimed to identify if uterine relaxants administered in the peri-implantation period during assisted reproduction treatments could improve pregnancy outcomes through literature search with no language restrictions. The review reports on 3546 patients in 17 randomized controlled trials published between 1993 and 2014. Women undergoing assisted reproduction techniques who either received a uterine relaxant agent in the peri-implantation period versus placebo or no treatment were included (...) The effect of peri-implantation administration of uterine relaxing agents in assisted reproduction treatment cycles: a systematic review and meta-analysis. Sub-endometrial junctional zone peristalsis is increased by ovarian stimulation and traumatic embryo transfer, and is linked with decreased implantation and pregnancy rates in assisted reproduction treatments. Various agents have been used to inhibit uterine hyper-peristalsis at the time of embryo transfer with conflicting results

2016 Reproductive biomedicine online

123. A comparison of the effects of reflexology and relaxation on pain in women with multiple sclerosis. (PubMed)

is greater than that of relaxation. Hence, these two methods can be recommended as effective techniques. (...) A comparison of the effects of reflexology and relaxation on pain in women with multiple sclerosis. Pain is a common and significant symptom in many individuals with multiple sclerosis (MS). The presence and severity of pain in individuals with MS has also been shown to be associated with higher levels of depression, functional impairment, and fatigue. It is common for MS patients and their caregivers to worry about narcotic addiction in the management of chronic pain. Therefore, this study

2016 Journal of complementary & integrative medicine

124. Effects of progressive muscle relaxation on cerebral activity: An fMRI investigation. (PubMed)

Effects of progressive muscle relaxation on cerebral activity: An fMRI investigation. Progressive muscle relaxation (PMR) is one of the self-management relaxation techniques that can be used in the general population and patients with specific issues. However, no study to date has revealed the brain activity associated with PMR. Therefore, we assessed the changes in brain activity induced by PMR using functional magnetic resonance imaging (fMRI).We conducted an intervention study with PMR (...) and control sessions. The subjects were twelve healthy adult men who had no prior experience of PMR.Subjects performed a control session in which muscles were repeatedly simply tensed and relaxed. Subsequently, a PMR session took place, during which muscle tension was reduced through a systematic procedure of tensing and relaxing of muscle groups combined with structured breathing.We identified and visualised brain activity based on individual and group-level analysis of fMRI data.Eleven subjects' data

2016 Complementary Therapies In Medicine

125. Phase transitions in semidefinite relaxations (PubMed)

SDP relaxations for statistical problems motivated by graph synchronization and community detection in networks. We map these optimization problems to statistical mechanics models with vector spins and use nonrigorous techniques from statistical mechanics to characterize the corresponding phase transitions. Our results clarify the effectiveness of SDP relaxations in solving high-dimensional statistical problems. (...) Phase transitions in semidefinite relaxations Statistical inference problems arising within signal processing, data mining, and machine learning naturally give rise to hard combinatorial optimization problems. These problems become intractable when the dimensionality of the data is large, as is often the case for modern datasets. A popular idea is to construct convex relaxations of these combinatorial problems, which can be solved efficiently for large-scale datasets. Semidefinite programming

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2016 Proceedings of the National Academy of Sciences of the United States of America

126. T2 relaxation time is related to liver fibrosis severity (PubMed)

T2 relaxation time is related to liver fibrosis severity The grading of liver fibrosis relies on liver biopsy. Imaging techniques, including elastography and relaxometric, techniques have had varying success in diagnosing moderate fibrosis. The goal of this study was to determine if there is a relationship between the T2-relaxation time of hepatic parenchyma and the histologic grade of liver fibrosis in patients with hepatitis C undergoing both routine, liver MRI and liver biopsy (...) , and to validate our methodology with phantoms and in a rat model of liver fibrosis.This study is composed of three parts: (I) 123 patients who underwent both routine, clinical liver MRI and biopsy within a 6-month period, between July 1999 and January 2010 were enrolled in a retrospective study. MR imaging was performed at 1.5 T using dual-echo turbo-spin echo equivalent pulse sequence. T2 relaxation time of liver parenchyma in patients was calculated by mono-exponential fit of a region of interest (ROI

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2016 Quantitative imaging in medicine and surgery

127. Ultrafast energy relaxation in single light-harvesting complexes (PubMed)

Ultrafast energy relaxation in single light-harvesting complexes Energy relaxation in light-harvesting complexes has been extensively studied by various ultrafast spectroscopic techniques, the fastest processes being in the sub-100-fs range. At the same time, much slower dynamics have been observed in individual complexes by single-molecule fluorescence spectroscopy (SMS). In this work, we use a pump-probe-type SMS technique to observe the ultrafast energy relaxation in single light-harvesting (...) complexes LH2 of purple bacteria. After excitation at 800 nm, the measured relaxation time distribution of multiple complexes has a peak at 95 fs and is asymmetric, with a tail at slower relaxation times. When tuning the excitation wavelength, the distribution changes in both its shape and position. The observed behavior agrees with what is to be expected from the LH2 excited states structure. As we show by a Redfield theory calculation of the relaxation times, the distribution shape corresponds

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2016 Proceedings of the National Academy of Sciences of the United States of America

128. Use of a Toric Intraocular Lens and a Limbal-Relaxing Incision for the Management of Astigmatism in Combined Glaucoma and Cataract Surgery (PubMed)

Use of a Toric Intraocular Lens and a Limbal-Relaxing Incision for the Management of Astigmatism in Combined Glaucoma and Cataract Surgery We report the surgical management of a patient with glaucoma undergoing cataract surgery with high preexisting astigmatism. A combination of techniques was employed for her astigmatism management.A 76-year-old female with 5.5 dpt of corneal astigmatism underwent surgery in her left eye consisting of one-site trabeculectomy, phacoemulsification, toric (...) intraocular lens implantation and a single inferior limbal-relaxing incision.Intraocular pressure control was achieved with no medication at 11 mm Hg; before the filtering procedure, the pressure was 16 mm Hg on two topical drugs. Astigmatism was reduced to 0.75 dpt, and both corrected and uncorrected visual acuity improved.Astigmatism management can have a good outcome in combined procedures. We encourage surgeons to address astigmatism in the preoperative planning of patients undergoing glaucoma surgery

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2016 Case reports in ophthalmology

129. Endothelin‐1 shifts the mediator of bradykinin‐induced relaxation from NO to H2O2 in resistance arteries from patients with cardiovascular disease (PubMed)

Endothelin‐1 shifts the mediator of bradykinin‐induced relaxation from NO to H2O2 in resistance arteries from patients with cardiovascular disease We tested the hypothesis that in resistance arteries from cardiovascular disease (CVD) patients, effects of an endothelium-dependent vasodilator depend on the contractile stimulus.Arteries dissected from parietal pericardium of cardiothoracic surgery patients were studied by myography and imaging techniques. Segments were sub-maximally contracted (...) by K(+) , the TxA2 analogue U46619 or endothelin-1 (ET-1).Relaxing effects of Na-nitroprusside were comparable, but those of bradykinin (BK) were bigger in the presence of ET-1 compared with K(+) or U46619. BK-induced relaxation was (i) abolished by L-NAME in K(+) -contracted arteries, (ii) partly inhibited by L-NAME in the presence of U46619 and (iii) not altered by indomethacin, L-NAME plus inhibitors of small and intermediate conductance calcium-activated K(+) channels, but attenuated

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2016 British journal of pharmacology

130. Band Inversion Amplifies 31P-31P Nuclear Overhauser Effects: Relaxation Mechanism and Dynamic Behavior of ATP in the Human Brain by 31P MRS at 7T (PubMed)

by frequency-selective inversion of either γ- or α-ATP. The rate of 31 P-31 P cross relaxation (0.21 ± 0.02 s-1 ) led to a τc value of (9.1 ± 0.8) × 10-8 s for ATP in human brain. The T1 relaxation of β-ATP is dominated by CSA over the DD mechanism (60%: 40%).The band inversion method proved effective in amplifying 31 P NOE, and thus facilitating ATP τc and relaxation measurements. This technique renders ATP a potentially useful reporter molecule for cellular environments. Magn Reson Med 77:1409-1418, 2017 (...) Band Inversion Amplifies 31P-31P Nuclear Overhauser Effects: Relaxation Mechanism and Dynamic Behavior of ATP in the Human Brain by 31P MRS at 7T To develop an improved method to measure the 31 P nuclear Overhauser effect (NOE) for evaluation of adenosine triphosphate (ATP) dynamics in terms of correlation time (τc ), and contribution of dipole-dipole (DD) and chemical shift anisotropy (CSA) mechanisms to T1 relaxation of ATP in human brain.The NOE of ATP in human brain was evaluated

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2016 Magnetic Resonance in Medicine

131. Progressive Relaxation in Hypnosis

Relaxation in Hypnosis Progressive Relaxation in Hypnosis Aka: Progressive Relaxation in Hypnosis From Related Chapters II. Preparation Call attention to body parts sequentially Patient relaxes each body part when prompted Variations of relaxation Tense and release muscle groups Imagine warmth (descending into warm bath) "Letting go" or experiencing "deep calm" Feedback Suggest that the patient is doing well Patient moving into nice state of relaxation III. Technique Take a deep breath and relax (...) Progressive Relaxation in Hypnosis Progressive Relaxation in Hypnosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Progressive

2018 FP Notebook

132. Progressive Relaxation

Relaxation Aka: Progressive Relaxation , Progressive Muscle Relaxation II. Preparation Patient sits in chair suitable for complete relaxation Loosen any tight fitting clothing III. Technique: Part 1 Now take a deep breath, which will help relax the muscles as you let your breath out again. Soon you will notice that your s begin to feel heavy and they will have a tendency to blink. They may blink more and more. They will grow heavier and heavier, heavier and heavier. You will find it harder and harder (...) listless now, a drowsy, listless feeling. It is very pleasant to feel so listless and drowsy. Let yourself relax still more. A feeling of well-being gradually comes over you, as though all your cares have rolled away, as though nothing matters, nothing at all. A feeling of "I don't care." You are so listless now. Give way to the feeling, as it is so pleasant. Just let yourself go, drifting deeper and deeper. Deeper with every breath you take. Deeper and still deeper. V. Technique: Part 3 Pay attention

2018 FP Notebook

133. Preoperative progressive pneumoperitoneum complementing chemical component relaxation in complex ventral hernia repair. (PubMed)

Preoperative progressive pneumoperitoneum complementing chemical component relaxation in complex ventral hernia repair. A rarely used technique for enabling closure of large ventral hernias with loss of domain is preoperative progressive pneumoperitoneum (PPP), which uses intermittent insufflation to gradually stretch the contracted abdominal wall muscles, increasing the capacity of the abdominal cavity. This allows the re-introduction of herniated viscera into the abdominal cavity and assists

2016 Surgical endoscopy

134. Preoperative chemical component relaxation using Botulinum toxin A: enabling laparoscopic repair of complex ventral hernia. (PubMed)

Preoperative chemical component relaxation using Botulinum toxin A: enabling laparoscopic repair of complex ventral hernia. Repair of complex ventral hernia can be very challenging for surgeons. Closure of large defects can have serious pathophysiological consequences. Botulinum toxin A (BTA) has recently been described to provide flaccid paralysis to abdominal muscles prior to surgery, facilitating closure and repair.This was a prospective observational study of 32 patients who underwent (...) injection to the muscles of the anterolateral abdominal wall is a safe and effective technique for the preoperative preparation of patients prior to laparoscopic mesh repair of complex ventral hernia. This technique elongates and thins the contracted and retracted musculature, enabling closure of large defects.

2016 Surgical endoscopy

135. Intestinal and vascular smooth muscle relaxant effect of Viscum album explains its medicinal use in hyperactive gut disorders and hypertension. (PubMed)

Intestinal and vascular smooth muscle relaxant effect of Viscum album explains its medicinal use in hyperactive gut disorders and hypertension. Viscum album has shown inhibitory effect on different smooth muscles but underlying mechanisms in gut and vascular smooth muscles are not well defined. Additionally, the plant has also importance in managing hyperactive gut and cardiovascular disorders. The current study was aimed to probe a pharmacological base of the smooth muscle relaxant effect of V (...) . album in gut and vascular preparations.V. album crude extract (Va. Cr) and its ethyl acetate fraction (Va. EtAc) were studied using in vitro techniques. The antispasmodic activity was performed using isolated rabbit jejunum while the vasorelaxant effects were studied in rabbit aortic rings.Va. Cr and Va. EtAc inhibited spontaneous and high K(+)-induced contractions with EC50 values of 0.31 mg/mL (0.15-0.57) and 0.62 mg/mL (0.3-0.95), respectively. This advocates an antispasmodic effect probably

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2016 BMC Complementary and Alternative Medicine

136. Imaging Cellular Dynamics with Spectral Relaxation Imaging Microscopy: Distinct Spectral Dynamics in Golgi Membranes of Living Cells (PubMed)

Imaging Cellular Dynamics with Spectral Relaxation Imaging Microscopy: Distinct Spectral Dynamics in Golgi Membranes of Living Cells Spectral relaxation from fluorescent probes is a useful technique for determining the dynamics of condensed phases. To this end, we have developed a method based on wide-field spectral fluorescence lifetime imaging microscopy to extract spectral relaxation correlation times of fluorescent probes in living cells. We show that measurement of the phase and modulation (...) of fluorescence from two wavelengths permit the identification and determination of excited state lifetimes and spectral relaxation correlation times at a single modulation frequency. For NBD fluorescence in glycerol/water mixtures, the spectral relaxation correlation time determined by our approach exhibited good agreement with published dielectric relaxation measurements. We applied this method to determine the spectral relaxation dynamics in membranes of living cells. Measurements of the Golgi-specific C6

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2016 Scientific reports

137. Bloch–Siegert B1-Mapping Improves Accuracy and Precision of Longitudinal Relaxation Measurements in the Breast at 3 T (PubMed)

Bloch–Siegert B1-Mapping Improves Accuracy and Precision of Longitudinal Relaxation Measurements in the Breast at 3 T Variable flip angle (VFA) sequences are a popular method of calculating T1 values, which are required in a quantitative analysis of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). B1 inhomogeneities are substantial in the breast at 3 T, and these errors negatively impact the accuracy of the VFA approach, thus leading to large errors in the DCE-MRI parameters (...) that could limit clinical adoption of the technique. This study evaluated the ability of Bloch-Siegert B1 mapping to improve the accuracy and precision of VFA-derived T1 measurements in the breast. Test-retest MRI sessions were performed on 16 women with no history of breast disease. T1 was calculated using the VFA sequence, and B1 field variations were measured using the Bloch-Siegert methodology. As a gold standard, inversion recovery (IR) measurements of T1 were performed. Fibroglandular tissue

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2016 Tomography

138. Graph Matching: Relax at Your Own Risk (PubMed)

theoretical support for their performance. A common technique is to relax the discrete problem to a continuous problem, therefore enabling practitioners to bring gradient-descent-type algorithms to bear. We prove that an indefinite relaxation (when solved exactly) almost always discovers the optimal permutation, while a common convex relaxation almost always fails to discover the optimal permutation. These theoretical results suggest that initializing the indefinite algorithm with the convex optimum might (...) Graph Matching: Relax at Your Own Risk Graph matching-aligning a pair of graphs to minimize their edge disagreements-has received wide-spread attention from both theoretical and applied communities over the past several decades, including combinatorics, computer vision, and connectomics. Its attention can be partially attributed to its computational difficulty. Although many heuristics have previously been proposed in the literature to approximately solve graph matching, very few have any

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2016 IEEE Transactions on Pattern Analysis and Machine Intelligence

139. Compliance Accelerates Relaxation in Muscle by Allowing Myosin Heads to Move Relative to Actin (PubMed)

distribution techniques to simulate the mechanical behavior of half-sarcomeres that were connected in series with springs of varying stiffness. (The springs mimic the combined effects of half-sarcomere heterogeneity and muscle's series elastic component.) Half-sarcomeres that shortened by >∼10 nm when they were activated subsequently relaxed with a biphasic profile; force initially declined slowly and approximately linearly before collapsing with a fast exponential time course. Stretches imposed during (...) Compliance Accelerates Relaxation in Muscle by Allowing Myosin Heads to Move Relative to Actin The mechanisms that limit the speed at which striated muscles relax are poorly understood. This work presents, to our knowledge, novel simulations that show that the time course of relaxation is accelerated by interfilamentary movement resulting from series compliance; force drops faster when myosin heads move relative to actin during relaxation. This insight was obtained by using cross-bridge

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2016 Biophysical journal

140. Measurement of Bound and Pore Water T1 Relaxation Times in Cortical Bone Using Three-Dimensional Ultrashort Echo Time Cones (3D UTE Cones) Sequences (PubMed)

Measurement of Bound and Pore Water T1 Relaxation Times in Cortical Bone Using Three-Dimensional Ultrashort Echo Time Cones (3D UTE Cones) Sequences We present three-dimensional ultrashort echo time Cones (3D UTE Cones) techniques for quantification of total water T1 ( T1TW), bound water T1 ( T1BW), and pore water T1 ( T1PW) in vitro and in vivo using a 3 Tesla (T) scanner.T1TW, T1BW, and T1PW were measured with three-dimensional (3D) Cones and adiabatic inversion recovery Cone (IR-Cone (...) ) sequences. Two-dimensional (2D) nonselective ultrashort echo time (UTE) techniques, including saturation recovery, variable repetition times (TRs), and inversion recovery (IR) preparation approaches were compared with 3D-Cones techniques on bovine cortical bone samples (n = 8). The 3D Cones sequences were used to measure T1TW, T1BW, and T1PW in the tibial midshaft of healthy volunteers (n = 8).Comparable T1 images were achieved for cortical bone between 3D Cones and 2D UTE techniques as well as those

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2016 Magnetic Resonance in Medicine

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