How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

83,862 results for

Relational Database

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. The ability of older adults to use customized online medical databases to improve their health-related knowledge. (PubMed)

The ability of older adults to use customized online medical databases to improve their health-related knowledge. Patient compliance with medical advice and recommended treatment depends on perception of health condition, medical knowledge, attitude, and self-efficacy. This study investigated how use of customized online medical databases, intended to improve knowledge in a variety of relevant medical topics, influenced senior adults' perceptions.Seventy-nine older adults in residence homes (...) ). No significant change occurred in the control group.Older adults improved their knowledge in desired medical topic areas using customized online medical databases. The study demonstrated how such databases help solve health-related questions among older adult population members, and that older patients appear willing to consider technology usage in information acquisition.Copyright © 2017 Elsevier B.V. All rights reserved.

2017 International journal of medical informatics

42. Network Meta-Analysis on the Effects of DNA Damage Response-Related Gene Mutations on Overall Survival of Breast Cancer Based on TCGA Database. (PubMed)

Network Meta-Analysis on the Effects of DNA Damage Response-Related Gene Mutations on Overall Survival of Breast Cancer Based on TCGA Database. The study was conducted for comparing the effects of 12 DNA damage response gene mutations (CHEK1, CHEK2, RAD51, BRCA1, BRCA2, MLH1, MSH2, ATM, ATR, MDC1, PARP1, and FANCF) on the overall survival (OS) of breast cancer (BC) patients. We searched the Cancer Genome Atlas (TCGA) database from inception to September 2016. Studies that investigated (...) the association between 12 DNA damage responses related genes and BC consolidated into this Network meta-analysis, by comparing directly or indirectly to evaluate the hazard rate (HR) value and the surface under the cumulative sequence ranking curves (SUCRA). In total four articles were involved. Our results demonstrated 12 DNA damage response gene mutations were associated to the poor prognosis of BC patients (CHEK1: HR = 9.9, 95%CI = 3.6-26.0; CHEK2: HR = 6.9, 95%CI = 3.1-15.0; RAD51: HR = 5.8, 95%CI = 2.2

2017 Journal of cellular biochemistry

43. Pediatric sialolithiasis is not related to oral or oropharyngeal infection: A population-based case control study using the Korean National Health Insurance Database. (PubMed)

Pediatric sialolithiasis is not related to oral or oropharyngeal infection: A population-based case control study using the Korean National Health Insurance Database. Poor oral hygiene is one of the risk factors for sialolithiasis particularly in adults; however the etiology of sialolithiasis in pediatric patients remains largely unknown. The purpose of this study is to identify the association between sialolithiasis and the oral/oropharyngeal infections in the pediatric population (...) , as surrogate indicators for oral hygiene and retrograde infections to the affected salivary gland.This was a population based case-control study using the Korean National Health Insurance Database. We identified 10,095 pediatric patients, diagnosed with sialolithiasis, as cases (study period 2011-2015) and 50,475 age/gender/residence matched subjects without sialolithiasis, but with unrelated diseases (e.g., simple trauma in extremities) were set as controls. Logistic regression analyses were conducted

2017 International Journal of Pediatric Otorhinolaryngology

44. Hospital mortality after hip fracture surgery in relation to length of stay by care delivery factors: A database study. (PubMed)

Hospital mortality after hip fracture surgery in relation to length of stay by care delivery factors: A database study. Two hypotheses were offered for the effect of shorter hospital stays on mortality after hip fracture surgery: worsening the quality of care and shifting death occurrence to postacute settings.We tested whether the risk of hospital death after hip fracture surgery differed across years when postoperative stays shortened, and whether care factors moderated

Full Text available with Trip Pro

2017 Medicine

45. Temporal Relations of Unplanned Readmissions Following Total Knee Arthroplasty: A Study of Large State Inpatient Databases. (PubMed)

Temporal Relations of Unplanned Readmissions Following Total Knee Arthroplasty: A Study of Large State Inpatient Databases. Centers for Medicare & Medicaid Services stipulate a 90-day global period for hospitals for unplanned readmissions after primary total knee arthroplasty (TKA). However, not all readmissions are directly attributable to index surgery, and reasons for readmissions vary during this time period. This study identifies causes and temporal relations of readmissions using large (...) state inpatient databases.State inpatient databases of New York and California were queried for all primary TKAs performed from 2005 to 2011 and frequencies of all causes of unplanned readmission were identified from 0 to 90 days after index surgery using the International Classification of Diseases, Ninth Revision, codes. Temporal differences in proportions of readmission diagnoses were tested using the Pearson chi-square test.The query identified 419,805 cases of primary TKA from 2005 to 2011

2017 Journal of Arthroplasty

46. Direct costs of osteoporosis-related hip fractures: protocol for a cross-sectional analysis of a national database. (PubMed)

Direct costs of osteoporosis-related hip fractures: protocol for a cross-sectional analysis of a national database. It is estimated that Iran accounted for about 1% of hip fracture burden of the world in 2007, but these data are based on incomplete evidence. As the country's population is ageing, it is expected that a dramatic rise in hip fracture incidence will result. There is no single national study that accurately estimates the incidence of all hip fractures in the country or identifies

Full Text available with Trip Pro

2017 BMJ open

47. Is admittance to specialised palliative care among cancer patients related to sex, age and cancer diagnosis? A nation-wide study from the Danish Palliative Care Database (DPD). (PubMed)

Is admittance to specialised palliative care among cancer patients related to sex, age and cancer diagnosis? A nation-wide study from the Danish Palliative Care Database (DPD). Specialised palliative care (SPC) takes place in specialised services for patients with complex symptoms and problems. Little is known about what determines the admission of patients to SPC and whether there are differences in relation to institution type. The aims of the study were to investigate whether cancer patients (...) ' admittance to SPC in Denmark varied in relation to sex, age and diagnosis, and whether the patterns differed by type of institution (hospital-based palliative care team/unit, hospice, or both).This was a register-based study of adult patients living in Denmark who died from cancer in 2010-2012. Data sources were the Danish Palliative Care Database, Danish Register of Causes of Death and Danish Cancer Registry. The associations between the explanatory variables (sex, age, diagnosis) and admittance to SPC

Full Text available with Trip Pro

2017 BMC Palliative Care

48. Database of resistance related metabolites in Wheat Fusarium head blight Disease (MWFD) (PubMed)

Database of resistance related metabolites in Wheat Fusarium head blight Disease (MWFD) https://bioinfo.nrc.ca/mwfd/index.php.© Her Majesty the Queen in Right of Canada, as represented by the Minister of [legal departmental name], 2017.

Full Text available with Trip Pro

2017 Database: The Journal of Biological Databases and Curation

49. The DrugAge database of aging‐related drugs (PubMed)

The DrugAge database of aging‐related drugs Aging is a major worldwide medical challenge. Not surprisingly, identifying drugs and compounds that extend lifespan in model organisms is a growing research area. Here, we present DrugAge (http://genomics.senescence.info/drugs/), a curated database of lifespan-extending drugs and compounds. At the time of writing, DrugAge contains 1316 entries featuring 418 different compounds from studies across 27 model organisms, including worms, flies, yeast (...) and mice. Data were manually curated from 324 publications. Using drug-gene interaction data, we also performed a functional enrichment analysis of targets of lifespan-extending drugs. Enriched terms include various functional categories related to glutathione and antioxidant activity, ion transport and metabolic processes. In addition, we found a modest but significant overlap between targets of lifespan-extending drugs and known aging-related genes, suggesting that some but not most aging-related

Full Text available with Trip Pro

2017 Aging cell

50. Database of Optimized Proteomic Quantitative Methods for Human Drug Disposition‐Related Proteins for Applications in Physiologically Based Pharmacokinetic Modeling (PubMed)

Database of Optimized Proteomic Quantitative Methods for Human Drug Disposition‐Related Proteins for Applications in Physiologically Based Pharmacokinetic Modeling The purpose of this study was to create an open access repository of validated liquid chromatography tandem mass spectrometry (LC-MS/MS) multiple reaction monitoring (MRM) methods for quantifying 284 important proteins associated with drug absorption, distribution, metabolism, and excretion (ADME). Various in silico (...) and experimental approaches were used to select surrogate peptides and optimize instrument parameters for LC-MS/MS quantification of the selected proteins. The final methods were uploaded to an online public database (QPrOmics; www.qpromics.uw.edu/qpromics/assay/), which provides essential information for facile method development in triple quadrupole mass spectrometry (MS) instruments. To validate the utility of the methods, the differential tissue expression of 107 key ADME proteins was characterized

Full Text available with Trip Pro

2017 CPT: pharmacometrics & systems pharmacology

51. EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network (PubMed)

EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network 28617437 2018 09 05 2018 11 13 2041-4889 8 6 2017 06 15 Cell death & disease Cell Death Dis EMT-Regulome: a database for EMT-related regulatory interactions, motifs and network. e2872 10.1038/cddis.2017.267 Zhao Zhangxiang Z College of Bioinformatics Science and Technology, Department of Systems Biology, Harbin Medical University, Harbin 150086, China. Training Center for Students Innovation

Full Text available with Trip Pro

2017 Cell death & disease

52. Weighted gene co-expression network analysis in identification of metastasis-related genes of lung squamous cell carcinoma based on the Cancer Genome Atlas database (PubMed)

Weighted gene co-expression network analysis in identification of metastasis-related genes of lung squamous cell carcinoma based on the Cancer Genome Atlas database Lung squamous cell carcinoma (lung SCC) is a common type of malignancy. Its pathogenesis mechanism of tumor development is unclear. The aim of this study was to identify key genes for diagnosis biomarkers in lung SCC metastasis.We searched and downloaded mRNA expression data and clinical data from The Cancer Genome Atlas (TCGA (...) ) database to identify differences in mRNA expression of primary tumor tissues from lung SCC with and without metastasis. Gene co-expression network analysis, protein-protein interaction (PPI) network, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis and quantitative real-time polymerase chain reactions (qRT-PCR) were used to explore the biological functions of the identified dysregulated genes.Four hundred and eighty-two differentially expressed genes (DEGs) were

Full Text available with Trip Pro

2017 Journal of thoracic disease

53. On the potential of preemptive genotyping towards preventing medication related adverse events: Results from the South Korean national health insurance database (PubMed)

On the potential of preemptive genotyping towards preventing medication related adverse events: Results from the South Korean national health insurance database 27873192 2017 10 26 2018 11 13 1179-1942 40 1 2017 01 Drug safety Drug Saf On the Potential of Preemptive Genotyping Towards Preventing Medication-Related Adverse Events: Results from the South Korean National Health Insurance Database. 1-2 10.1007/s40264-016-0476-z Schildcrout Jonathan S JS Department of Biostatistics, Vanderbilt (...) United States R01 GM105688 GM NIGMS NIH HHS United States Letter Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. Comment New Zealand Drug Saf 9002928 0114-5916 IM Drug Saf. 2017 Jan;40(1):65-80 27638658 Databases, Factual Genotype Humans National Health Programs Jonathan S. Schildcrout, Joshua C. Denny, and Dan M. Roden have no conflicts of interests directly relevant to the content of this commentary. 2016 11 23 6 0 2017 10 27 6 0 2016 11 23 6 0 ppublish 27873192 10.1007

Full Text available with Trip Pro

2017 Drug Safety

54. An OMOP CDM-Based Relational Database of Clinical Research Eligibility Criteria (PubMed)

An OMOP CDM-Based Relational Database of Clinical Research Eligibility Criteria Eligibility criteria are important for clinical research protocols or clinical practice guidelines for determining who qualify for studies and to whom clinical evidence is applicable, but the free-text format is not amenable for computational processing. In this paper, we described a practical method for transforming free-text clinical research eligibility criteria of Alzheimer's clinical trials into a structured (...) relational database compliant with standards for medical terminologies and clinical data models. We utilized a hybrid natural language processing system and a concept normalization tool to extract medical terms in clinical research eligibility criteria and represent them using the OMOP Common Data Model (CDM) v5. We created a database schema design to store syntactic relations to facilitate efficient cohort queries. We further discussed the potential of applying this method to trials on other diseases

Full Text available with Trip Pro

2017 Studies in health technology and informatics

55. Utilization of Osteoporosis-Related Health Services: Use of Data from the Korean National Health Insurance Database 2008–2012 (PubMed)

Utilization of Osteoporosis-Related Health Services: Use of Data from the Korean National Health Insurance Database 2008–2012 Osteoporosis and its related fractures are increasingly being recognized as major health problems because of the rapidly increasing elderly population. In this study, we investigated the annual trend of osteoporosis-related health services utilization.Participants aged over 50 years were identified from the Korean National Health Insurance Service database between 2008 (...) the Korea National Health and Nutrition Examination Survey from 2008 to 2010. Less than 60% of patients with osteoporosis were estimated to have utilized medical services because of osteoporosis. Drug treatment rates were 34.1%, 31.1%, and 33.5% in 2008, 2009, and 2010, respectively.This study demonstrated an increasing trend in the utilization of the osteoporosis-related health services from 2008 to 2012 in Korea. The proportion of newly diagnosed osteoporosis patients and the prevalence of access

Full Text available with Trip Pro

2017 Journal of Korean medical science

56. rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks (PubMed)

rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks Here, we present the updated rSNPBase 3.0 database (http://rsnp3.psych.ac.cn), which provides human SNP-related regulatory elements, element-gene pairs and SNP-based regulatory networks. This database is the updated version of the SNP regulatory annotation database rSNPBase and rVarBase. In comparison to the last two versions, there are both structural and data (...) adjustments in rSNPBase 3.0: (i) The most significant new feature is the expansion of analysis scope from SNP-related regulatory elements to include regulatory element-target gene pairs (E-G pairs), therefore it can provide SNP-based gene regulatory networks. (ii) Web function was modified according to data content and a new network search module is provided in the rSNPBase 3.0 in addition to the previous regulatory SNP (rSNP) search module. The two search modules support data query for detailed

Full Text available with Trip Pro

2017 Nucleic acids research

57. Estimating the risk of severe hypoglycemic event related to glucose-lowering treatment among Italian patients with diabetes: the HYPOTHESIS database (PubMed)

Estimating the risk of severe hypoglycemic event related to glucose-lowering treatment among Italian patients with diabetes: the HYPOTHESIS database The primary objective of this study was to estimate 1) the annual risk of undergoing a severe hypoglycemic event in Italian patients with diabetes and 2) the risk of hospitalization following such event. From the HYPOTHESIS database, powered by 46 emergency departments covering a 12-million-odd population, data were extracted of 1,922 hypoglycemic (...) with that for subjects treated with OHA (p<0.02). Death occurs in 7% of hospitalized patients. Older age (p<0.0001) and comorbidities (p<0.0001) were risk factors for hypoglycemia-related hospitalization. Treatments with insulin alone (p<0.005) or in combination (p<0.049) were negatively associated with hospital admission. Severe hypoglycemic events associated with the use of oral glucose-lowering agents carry the highest risk of hospital treatment. As such, they are also likely to generate higher tangible

Full Text available with Trip Pro

2017 ClinicoEconomics and Outcomes Research: CEOR

58. Therapeutic endoscopy-related GI bleeding and thromboembolic events in patients using warfarin or direct oral anticoagulants: results from a large nationwide database analysis. (PubMed)

Therapeutic endoscopy-related GI bleeding and thromboembolic events in patients using warfarin or direct oral anticoagulants: results from a large nationwide database analysis. To compare the risks of postendoscopy outcomes associated with warfarin with direct oral anticoagulants (DOACs), taking into account heparin bridging and various types of endoscopic procedures.Using the Japanese Diagnosis Procedure Combination database, we identified 16 977 patients who underwent 13 types of high-risk

Full Text available with Trip Pro

2017 Gut

59. Current Trends of Lung Cancer Surgery and Demographic and Social Factors Related to Changes in the Trends of Lung Cancer Surgery: An Analysis of the National Database from 2010 to 2014 (PubMed)

Current Trends of Lung Cancer Surgery and Demographic and Social Factors Related to Changes in the Trends of Lung Cancer Surgery: An Analysis of the National Database from 2010 to 2014 We investigated current trends in lung cancer surgery and identified demographic and social factors related to changes in these trends.We estimated the incidence of lung cancer surgery using a procedure code-based approach provided by the Health Insurance Review and Assessment Service (http://opendata.hira.or.kr

Full Text available with Trip Pro

2016 Cancer research and treatment : official journal of Korean Cancer Association

60. Skeleton Genetics: a comprehensive database for genes and mutations related to genetic skeletal disorders (PubMed)

Skeleton Genetics: a comprehensive database for genes and mutations related to genetic skeletal disorders Genetic skeletal disorders (GSD) involving the skeletal system arises through disturbances in the complex processes of skeletal development, growth and homeostasis and remain a diagnostic challenge because of their clinical heterogeneity and genetic variety. Over the past decades, tremendous effort platforms have been made to explore the complex heterogeneity, and massive new genes (...) and mutations have been identified in different GSD, but the information supplied by literature is still limited and it is hard to meet the further needs of scientists and clinicians. In this study, combined with Nosology and Classification of genetic skeletal disorders, we developed the first comprehensive and annotated genetic skeletal disorders database, named 'SkeletonGenetics', which contains information about all GSD-related knowledge including 8225 mutations in 357 genes, with detailed information

Full Text available with Trip Pro

2016 Database: The Journal of Biological Databases and Curation

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>