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Update Posted : July 19, 2017 See Sponsor: Smart Vision Labs Information provided by (Responsible Party): Smart Vision Labs Study Details Study Description Go to Brief Summary: The purpose of the study is to compare the final glasses prescription based on refraction obtained with SVOne device to the final prescription obtained via subjective manifest refraction. Condition or disease Intervention/treatment RefractiveErrors Diagnostic Test: Refraction Detailed Description: Uncorrected refractiveerror (...) is the leading cause of vision impairment and the second leading cause of blindness worldwide, affecting 1 in 90 individuals (1). In the US population approximately 14 million individuals aged 12 years or older have visual impairment (defined as distance visual acuity of 20/50 or worse), of which more than 11 million individuals (2) could have their vision improved to 20/40 or better with refractive correction. Uncorrected refractiveerror impacts all aspects of life, including, but not limited to, loss
Is an objective refraction optimised using the visual Strehl ratio better than a subjective refraction? To prospectively examine whether using the visual image quality metric, visual Strehl (VSX), to optimise objective refraction from wavefront error measurements can provide equivalent or better visual performance than subjective refraction and which refraction is preferred in free viewing.Subjective refractions and wavefront aberrations were measured on 40 visually-normal eyes of 20 subjects (...) over the subjective by 72% of myopic eyes when not dilated. For four habitually undercorrected high hyperopic eyes, the VSX-objective refraction was more positive in spherical power and VA poorer than with the subjective refraction.A method of simultaneously optimising sphere, cylinder, and axis from wavefront error measurements, using the visual image quality metric VSX, is described. In myopic subjects, visual performance, as measured by HC and LC VA, with this VSX-objective refraction was found
depth (S1) and the vitreous length (S2). Gaussian optics was used to calculate the change rate of refractiveerror per unit amount of ocular components of a human eye (the rate function M). A new criterion of myopia was presented via an effective axial length.For typical corneal and lens power of 42 and 21.9 diopters, the rate function Mj (j=1 to 6) were calculated for a 1% change of r1, r2, R1, R2, t, T (in diopters) M1=+0.485, M2=-0.063, M3=+0.053, M4=+0.091, M5=+0.012, and M6=-0.021 diopters (...) Human eye ocular component analysis for refractive state and refractive surgery To analyze the clinical factors influencing the human vision corrections via the changing of ocular components of human eye in various applications; and to analyze refractive state via a new effective axial length.An effective eye model was introduced by the ocular components of human eye including refractive indexes, surface radius (r1, r2, R1, R2) and thickness (t, T) of the cornea and lens, the anterior chamber
Meditec, Germany); preoperative SNR values were used to divide the eyes into three groups (Group 1; SNR <10, Group 2; 10 ≤ SNR <50, Group 3; 50 ≤ SNR <100). One month and 6 months after cataract surgery, the manifest refraction spherical equivalents (MRSE) were measured. The mean numeric errors (MNE), the mean of the difference between postoperative MRSE, and preoperative target refraction, using the various intraocular lens (IOL) formulas, were calculated and compared among the three groups.One month (...) The influence of low signal-to-noise ratio of axial length measurement on prediction of target refraction, achieved using IOLMaster. To evaluate the influence of low signal-to-noise ratio (SNR) of axial length measurement, achieved using IOLMaster, on prediction of target refraction.A total of 131 eyes of 131 patients who underwent phacoemulsification with posterior chamber lens implantation were enrolled. Preoperative axial length measurements were performed with the IOLMaster 500 (Carl Zeiss
Wavefront excimer laser refractive surgery for adults with refractiveerrors [Cochrane protocol] Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address (...) is the typical model of choice for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include various species, strains and treatment regimes, for which different true effects are likely to exist
Behavior disorders in children with significant refractiveerrors To evaluate the frequency of behavioral disorders in children with significant refractiveerror and to compare the results with those of emmetropic children.In this prospective, comparative study from January to September 2013, refractiveerrors of all 5-12-year-old children who referred to a general eye clinic were recorded. A validated Persian version of the Rutter A scale was filled out by the parents for the evaluation (...) of the child's behavioral disorders. The Rutter A scale scores of children with significant refractiveerror were compared with those of emmetropic eyes. Student t test, Chi square test, and Fisher's exact test were used for analysis. Differences with a P value less than 0.05 were considered significant.One hundred eighty-three patients, including 101 patients with significant refractiveerror and 82 emmetropic subjects, were studied. Overall, 44 patients (24%) had behavioral disorders, according
Comparison of RefractiveError Changes in Retinopathy of Prematurity Patients Treated with Diode and Red Lasers. To compare refractiveerror changes in retinopathy of prematurity (ROP) patients treated with diode and red lasers.A randomized double-masked clinical trial was performed, and infants with threshold or prethreshold type 1 ROP were assigned to red or diode laser groups. Gestational age, birth weight, pretreatment cycloplegic refraction, time of treatment, disease stage, zone (...) and disease severity were recorded. Patients received either red or diode laser treatment and were regularly followed up for retina assessment and refraction. The information at month 12 of corrected age was considered for comparison.One hundred and fifty eyes of 75 infants were enrolled in the study. Seventy-four eyes received diode and 76 red laser therapy. The mean gestational age and birth weight of the infants were 28.6 ± 3.2 weeks and 1,441 ± 491 g, respectively. The mean baseline refractiveerror
(FS200 femtosecond and EX500 excimer lasers) were randomized for treatment as follows: one eye with the standard clinical refraction (group A) and the contralateral eye with the topographic astigmatic power and axis (topography-modified treatment refraction; group B). All cases were evaluated pre- and post-operatively for the following parameters: refractiveerror, best corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA), topography (Placido-disk based) and tomography (...) (Scheimpflug-image based), wavefront analysis, pupillometry, and contrast sensitivity. Follow-up visits were conducted for at least 12 months.Mean refractiveerror was -5.5 D of myopia and -1.75 D of astigmatism. In group A versus group B, respectively, the average UDVA improved from 20/200 to 20/20 versus 20/16; post-operative CDVA was 20/20 and 20/13.5; 1 line of vision gained was 27.8% and 55.6%; and 2 lines of vision gained was 5.6% and 11.1%. In group A, 27.8% of eyes had over -0.50 diopters
Comparing habitual and i. Scription refractions. Many patients voice concerns regarding poor night vision, even when they see 20/20 or better in the exam room. During mesopic and scotopic conditions the pupil size increases, increasing the effects on visual performance of uncorrected (residual) refractiveerrors. The i.Scription refraction method claims to optimize traditional refractions for mesopic and scotopic conditions, by using the information that the Zeiss i.Profilerplus gathers (...) of ocular aberrations (low and high order). The aim of this study was to investigate any differences between habitual and i.Scription refractions and their relationship to night vision complaints.Habitual, subjective, and i.Scription refractions were obtained from both eyes of eighteen subjects. Low and high order aberrations of the subjects were recorded with the Zeiss i.Profilerplus. The root mean square (RMS) metric was calculated for small (3 mm) and maximum pupil sizes. Subjects rated
were performed of the accuracy of three methods using surgically induced change in refraction (ie, Masket, Modified Masket, and Barrett True-K formulas) and three methods using no previous data (ie, Shammas, Haigis-L, and Barrett True-K No History formulas). The average of all formulas was also analyzed and compared.Thirty-six eyes of 36 patients were included. All formulas, except for the Masket, Modified Masket, and Barrett True-K formulas, had myopic mean numerical errors that were significantly (...) different from zero (P ⩽ .01). The median absolute error of the Shammas formula (0.52 diopters [D]) was significantly higher compared to all of the other formulas (P < .05), except for the Haigis-L formula (P = .09). Comparing the formulas using no previous data, the Barrett True-K No History formula had the lowest median absolute error (0.33 D, P < .001).The Shammas formula showed the least accuracy in predicting IOL power in eyes with multifocal IOL implantation after previous corneal refractive laser
Short-term Refractive Effects of Propranolol Hydrochloride Prophylaxis on Retinopathy of Prematurity in Very Preterm Newborns. Retinopathy of prematurity (ROP) is one of the major problems of surviving premature infants with several ophthalmic morbidities such as increased risk of refractiveerrors, strabismus, and cortical visual impairment. Use of propranolol hydrochloride (PH) for the prevention of ROP is a new promising treatment modality. However, long-term effects are still to be defined (...) . In our study, we aimed to investigate the short-term refractive effects of PH used for ROP prophylaxis in very preterm newborns.This is a prospective, randomized, double-blind, placebo-controlled study. Very preterm newborns with a birthweight less than or equal to 1500 g and/or born prior to 32 gestational weeks were included in the study. The subjects were randomly divided into two groups: control group (CG, n = 37) given placebo and PH group (PHG, n = 34) given PH starting from 4 weeks after birth
Refractive Laser-Assisted Cataract Surgery vs. Conventional Manual Surgery: Comparing Efficacy and Safety in 3144 Eyes. To report on outcomes of efficacy and safety in one of the largest series of eyes undergoing either conventional manual cataract surgery (MCS) or refractive femtosecond laser-assisted cataract surgery (ReLACS).Retrospective, consecutive, interventional comparative case series.This study included 3144 consecutive eyes of which 1580 were treated via MCS and 1564 were treated via (...) ReLACS at Uptown Surgical Centre in Vaughan, Canada. Preoperative characteristics, best corrected visual acuity (BCVA), mean absolute spherical error (MAE), rates of intraoperative posterior capsular rupture (PCR), and postoperative complications were evaluated.Across all eyes, ReLACS was superior to MCS for reducing surgical time (MCS: 7.7±0.1 min vs. ReLACS: 6.8±0.1 min, p<0.001), being less associated with postoperative cystoid macular edema (OR=0.36, 95% CI: 0.14-0.91, p=0.031), and for reducing
Anterior chamber depth - a predictor of refractive outcomes after age-related cataract surgery. Anterior chamber depth (ACD) is becoming a hot topic and plays an important role in correcting the refractiveerrors (REs) after cataract surgery. The aim of this study was to assess the ACD changes and their relationship with the REs after phacoemulsification and intraocular lens (IOL) implantation in patients with age-related cataracts.One hundred forty-five eyes of 125 age-related cataract (...) of this study showed that the ACD deepened and was associated with a concurrent RE after cataract surgery. Postoperative changes in the ACD were related to the preoperative ACD and AL, which determined the refraction status and visual quality. The regression formula of the postoperative ACD could provide a theoretical basis for predicting refractiveerrors in the clinic.
Evaluation of total keratometry and its accuracy for intraocular lens power calculation in eyes after corneal refractive surgery. To compare the accuracy of total keratometry (TK) and standard keratometry (K) from a swept-source optical coherence tomography biometer for intraocular lens (IOL) power calculation in eyes with previous corneal refractive surgery.Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.Retrospective case series.The differences between the TK and K (...) and their association with K were assessed. For IOL power calculation, combinations of 1) K with Haigis, Haigis-L, and Barrett True-K, and 2) TK with Haigis (Haigis-TK) were used. The mean absolute error (MAE) and the percentages of eyes within prediction errors of ± 0.50 diopters (D), ± 1.00 D, and ± 2.00 D were calculated.The study comprised 129 eyes. For Haigis, Haigis-L, Barrett True-K, and Haigis-TK, respectively, the MAEs were 0.72 D, 0.61 D, 0.54 D, and 0.50 D in the myopic laser in situ keratomileusis
of a femtosecond laser. However, the reported retinal detachment rates after corneal refractive surgery are similar to those of an unoperated myopic cohort. No differences were found between retinal detachment rates in laser in situ keratomileusis and superficial corneal refractive surgery. The pooled analysis found an overall risk of developing retinal detachment after laser in situ keratomileusis of 0.08% (95% CI: 0.69% to 0.82%). Higher preoperative refractiveerror, patient age, and male gender were (...) associated with an increased risk of retinal detachment.The current analysis presents no convincing evidence to support the causal relationship between corneal refractive surgery and retinal detachment. Patients at risk of developing retinal detachment should be treated with caution and informed that corneal refractive surgery reduces the refractiveerror, but does not eliminate the risks related to myopia. [J Refract Surg. 2019;35(8):517-524.].Copyright 2019, SLACK Incorporated.
A Randomized Noninferiority Trial of Wearing Adjustable Glasses versus Standard and Ready-made Spectacles among Chinese Schoolchildren: Wearability and Evaluation of Adjustable Refraction III. To compare wear of standard, adjustable, and ready-made glasses among children.Randomized, controlled, open-label, noninferiority trial.Students aged 11 to 16 years with presenting visual acuity (VA) ≤6/12 in both eyes, correctable to ≥6/7.5, subjective spherical equivalent refractiveerror (SER) ≤-1.0 (...) diopters (D), astigmatism and anisometropia both <2.00 D, and no other ocular abnormalities.Participants were randomly allocated (1:1:1) to standard glasses, ready-made glasses, or adjustable glasses based on self-refraction. We recorded glasses wear on twice-weekly covert evaluation by head teachers (primary outcome), self-reported and investigator-observed wear, best-corrected visual acuity (BCVA) (not prespecified), children's satisfaction, and value attributed to glasses.Proportion of glasses wear
Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular RefractiveErrors Compared to Habitually Worn Scleral Lenses Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular RefractiveErrors Compared to Habitually Worn Scleral Lenses - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular RefractiveErrors Compared to Habitually Worn Scleral Lenses The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier
The effectiveness of school vision screening programmes in Africa for reducing the proportion of children with uncorrected refractiveerror: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr (...) difference; incidence of metastasis: risk ratio. ">Effect measure The random-effects model is the typical model of choice for pre-clinical meta-analyses. This is because in the fixed-effect model, it is assumed that the differences in observed effect between studies is solely due to sampling error (i.e. differences in sample size), and that the true effect is the same (fixed) across all studies. However, this assumption is unlikely to hold true for data from animal studies, which generally include