How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

404 results for


Latest & greatest

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from Bermuda. (PubMed)

isolates were completely analyzed and were all resistant to vancomycin, susceptible to linezolid and quinupristin/dalfopristin, positive for vanA and esp genes. The MLST analysis confirmed most isolates were of the sequence types linked to clonal complex 17 (CC17) that is widely associated with outbreaks in hospitals. Infection control measures, antibiotic stewardship, and surveillance activities will continue to be a priority in hospital on the Island.

Full Text available with Trip Pro

2017 PLoS ONE

23. Antibiotic Coverage in Atypical Pathogens for Adults Hospitalized With Community-Acquired Pneumonia

* or doxycyclin* or t etracyclin* or chloramphenicol* or streptogramin* or ketolid* or erythromycin* or roxithromycin* or azithromycin* or clarithro mycin* or ciprofloxacin* or ofloxacin* or levofloxacin* or trovaflox acin* or moxifloxacin* or grepafloxacin* or tigecyclin* or minocyclin* or pristinamycin* or quinupristin* or telithromycin*).ti,ab. 616190 12 or/4-11 1673803 13 3 and 12 109019 14 Meta 40231 15 Meta-Analysis/ use mesz or exp Technology Assessment, Biomedical/ use mesz 49071 16 Meta (...) * or quinupristin* or telithromycin*).ti,ab. 17008 12 or/4-11 28510 13 3 and 12 2274 Antibiotic Coverage in Atypical Pathogens for Adults Hospitalized With Community-Acquired Pneumonia: A Rapid Review. November 2013; pp. 1–24 17 14 Meta 464 15 Meta-Analysis/ use acp,cctr,coch,clcmr,dare,clhta,cleed 21 16 exp Technology Assessment, Biomedical/ use acp,cctr,coch,clcmr,dare,clhta,cleed 438 17 (meta analy* or metaanaly* or pooled analysis or (systematic* adj2 review*) or published studies or published

2013 Health Quality Ontario

24. Shorter Versus Longer Duration of Antibiotic Therapy in Patients With Community-Acquired Pneumonia

* or roxithromycin* or azithromycin* or clarithro mycin* or ciprofloxacin* or ofloxacin* or levofloxacin* or trovaflox acin* or moxifloxacin* or grepafloxacin* or tigecyclin* or minocyclin* or pristinamycin* or quinupristin* or telithromycin*).ti,ab. 635233 12 or/4-11 1707130 13 3 and 12 111685 14 Meta 40966 15 Meta-Analysis/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed or exp Technology Assessment, Biomedical/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed 49796 16 Meta Analysis/ use emez

2013 Health Quality Ontario

25. Monotherapy Versus Combination Therapy for Adults Hospitalized for Community-Acquired Pneumonia

* or t etracyclin* or chloramphenicol* or streptogramin* or ketolid* or erythromycin* or roxithromycin* or azithromycin* or clarithro mycin* or ciprofloxacin* or ofloxacin* or levofloxacin* or trovaflox acin* or moxifloxacin* or grepafloxacin* or tigecyclin* or minocyclin* or pristinamycin* or quinupristin* or telithromycin*).ti,ab. 634694 12 or/4-11 1705779 13 3 and 12 111562 14 exp Drug Therapy, Combination/ use mesz,acp,cctr,coch,clcmr,dare,clhta,cleed 280028 15 exp drug combination/ use emez

2013 Health Quality Ontario

27. Meta-analysis of randomized controlled trials of vancomycin for the treatment of patients with gram-positive infections: focus on the study design

trials) and daptomycin, tigecycline, ceftaroline, ceftobiprole, quinupristin-dalfopristin, dalbavancin and iclaprim in fewer trials. Most studies allowed other concomitant antibiotics. Most studies were of adult patients and three were of children; 22 were of hospitalised patients. Most studies concentrated on one type of infection. Two independent reviewers performed the study selection. Assessment of study quality Study quality was assessed using a modified Jadad scale with five criteria

Full Text available with Trip Pro

2013 DARE.

28. Assessment of disinfectant and antibiotic susceptibility patterns and multi-locus variable number tandem repeat analysis of Staphylococcus epidermidis isolated from blood cultures (PubMed)

susceptible to linezolid and quinupristin/dalfopristin, respectively. A total of 55.7% of the isolates were found to be multidrug resistant (MDR). All isolates had MICs of CHG-A and ISP-QAC of 8 folds lower and MIC of QAC-B 6 folds lower than that suggested by the manufacturers. The genes qacA/B and smr were found in 28 (24.3%) and 14 (12.2%) isolates, respectively. MLVA typing of the S. epidermidis isolates resulted in 106 VNTR patterns and 102 MLVA types for the 112 S. epidermidis isolates, considering

Full Text available with Trip Pro

2018 Iranian journal of microbiology

29. Antimicrobial susceptibility pattern of Staphylococcus aureus isolates from clinical specimens at Kenyatta National Hospital (PubMed)

for quinupristin/dalfopristin (100%), tigecycline (98.2), imipenem (98%), nitrofurantoin (97.6%), linezolid (97.3%), teicoplanin (97.1%) and vancomycin (95.1%). High resistance was recorded against penicillin G (91.9%), trimethoprim/sulfamethoxazole (56.9%) and tetracycline (33.2%). MRSA prevalence among the patients at KNH was 27.8%. Highest proportion (80%) of MRSA was in burns unit. Both MRSA and MSSA were highly susceptible to quinupristin/dalfopristin, tigecycline, linezolid, nitrofurantoin, ampicillin

Full Text available with Trip Pro

2018 BMC research notes

30. Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM

of the following antibiotics is an exclusion criterion: azithromycin and other macrolides, doxycycline and related tetra- or glycylcyclines, fluoroquinolones, rifampin, quinupristin-dalfopristin, and linezolid. Plans to move to another location that would preclude study follow-up appointments in clinic or by mail-in in the next 30 days. Use of any investigational drug contraindicated to treatment with azithromycin or doxycycline within 7 days before enrollment. Previous enrollment in this trial. Any other

2018 Clinical Trials

31. Biodiversity and Microbial Resistance of Lactobacilli Isolated From the Traditional Greek Cheese Kopanisti (PubMed)

. Resistance against penicillin G, ampicillin/sulbactam, clindamycin, chloramphenicol, streptomycin, trimethoprim, metronidazole, vancomycin, teichoplanin, and quinupristin/dalvopristin was significantly enhanced, while the resistance against ampicillin, erythromycin, oxytetracycline, gentamycin, and fucidic acid was significantly reduced. These changes during ripening suggest that resistance to antimicrobials is a dynamic process subjected to environmental factors. The biodiversity of isolated

Full Text available with Trip Pro

2018 Frontiers in microbiology

32. Prevalence and Genetic Basis of Antimicrobial Resistance in Non-aureus Staphylococci Isolated from Canadian Dairy Herds (PubMed)

to determine resistance profiles for 1,702 isolates from 89 dairy herds. Additionally, 405 isolates were sequenced to screen for resistance determinants. Antimicrobial resistance was clearly species-dependent. Resistance to quinupristin/dalfopristin was common in Staphylococcus gallinarum (prevalence of 98%), whereas S. cohnii and S. arlettae were frequently resistant to erythromycin (prevalence of 63 and 100%, respectively). Prevalence of resistance was 10% against β-lactams and tetracyclines. In contrast

Full Text available with Trip Pro

2018 Frontiers in microbiology

33. Prevalence and molecular characterization of Staphylococcus aureus from human stool samples (PubMed)

study.Out of 625 patients included in the final study, 58 were positive for S. aureus (9.3%). One isolate was positive for the PVL gene. A high number of isolates were resistant to multiple antibiotics including oxacillin (43.1%), erythromycin (51.7%), and levofloxacin (41.4%). All isolates were susceptible to vancomycin, daptomycin, linezolid, and quinupristin-dalfopristin. In the nested study, having a disease or condition of the gastrointestinal tract significantly increased the odds of intestinal

Full Text available with Trip Pro

2018 Antimicrobial resistance and infection control

34. Antimicrobial-resistant Escherichia coli and Enterococcus spp. isolated from Miranda donkey (Equus asinus): an old problem from a new source with a different approach. (PubMed)

independent animals. Antibiotic resistance was determined by the disc diffusion method. Carriage of genes coding for antibiotic-resistant and virulent factors was analysed by PCR.A total of 66 E. coli and 41 enterococcal isolates were detected, with Enterococcus faecium (61 %) and Enterococcus hirae (24 %) being the most prevalent species. For enterococcal isolates, high percentages of resistance rates to tetracycline (68.3 %), quinupristin/dalfopristin (51.2 %) and ciprofloxacin (48.8 %) were observed

Full Text available with Trip Pro

2017 Journal of Medical Microbiology

35. The combined effect of the Cfr methyltransferase and ribosomal protein L3 mutations on resistance to ribosome targeting antibiotics. (PubMed)

rate decreases. The presence of Cfr has a very minor influence on the growth rate. The resistance of the transformants to linezolid, tiamulin, florfenicol, and Synercid (a combination of quinupristin and dalfopristin [Q-D]) was measured by MIC assays. The resistance from Cfr was, in all cases, stronger than the effects of the L3 mutations, but various effects were obtained with the combinations of Cfr and L3 mutations ranging from a synergistic to an antagonistic effect. Linezolid and tiamulin

Full Text available with Trip Pro

2017 Antimicrobial Agents and Chemotherapy

36. Role of Combination Antimicrobial Therapy for Vancomycin-Resistant Enterococcus faecium Infections: Review of the Current Evidence. (PubMed)

, and aminoglycosides, further complicates the treatment of these infections. Of particular concern are Enterococcus faecium strains that are associated with the highest rate of vancomycin resistance. The introduction of antimicrobial agents with specific activity against vancomycin-resistant Enterococcus (VRE) faecium including daptomycin, linezolid, quinupristin-dalfopristin, and tigecycline did not completely resolve this clinical dilemma. In this review, the mechanisms of action and resistance to currently

Full Text available with Trip Pro

2017 Pharmacotherapy

37. Central Venous Access in Oncology

-resistant Linezolidordaptomycin Or Quinupristin/dalfopristin Gram-negative Escherichiacoliand Klebsiellaspp. ESBL-negative: Third-generationcephalosporin(e.g.ceftriaxone) Or Ciprofloxacinoraztreonam ESBL-positive: Carbapenem(e.g.ertapenem,imipenem,meropenemor doripenem) Or Ciprofloxacinoraztreonam Ciprofloxacinoramikacin,bothatthedoseof2g/l, plusheparin20IU/ml Taurolidine2.5ml,eithercombinedwith4%sodium citrate,sodiumheparin2500IUorwith25000IU urokinase Gentamicin5mg/mlplusEDTA30mg/mlfor3days (...) Daptomycin2.5mg/ml,dilutedinlactatedRinger’s solution Taurolidine2.5ml,eithercombinedwith4%sodium citrate,sodiumheparin2500IUorwith25000IU urokinase Gentamicin5mg/mlplusEDTA30mg/ml,for3–5 days,inadditiontosystemicvancomycin S. coagulase-negative Methicillin-susceptible Nafcillinoroxacillin Or First-generationcephalosporinorvancomycin Methicillin-resistant Vancomycin or Daptomycin,linezolidorquinupristin/dalfopristin Vancomycin1–5mg/ml,addedtoheparin2500– 5000IU/ml,lockfor12h/day Daptomycin5mg/ml

2015 European Society for Medical Oncology

38. Antimicrobial Resistance and Molecular Characterization of Staphylococcus aureus Causing Childhood Pneumonia in Shanghai (PubMed)

isolates from the respiratory specimens were characterized by antimicrobial susceptibility, agr typing, toxin genes, multilocus sequence typing (MLST), spa, and SCCmec typing. Fifty-eight (54.2%, 58/107) were MSSA (methicillin-susceptible Staphylococcus aureus) and 49 (45.8%, 49/107) were MRSA. No isolates were found resistant to teicoplanin, sulfamethoxazole/trimethoprim, rifampicin, quinupristin/dalfopristin, linezolid, or vancomycin. However, these isolates showed high resistant rates

Full Text available with Trip Pro

2017 Frontiers in microbiology

39. Factors associated with Staphylococcus aureus nasal carriage and molecular characteristics among the general population at a Medical College Campus in Guangzhou, South China (PubMed)

) genes. 83.6% of the S. aureus isolates were resistant to penicillin, all isolates were susceptible to quinupristin/dalfopristin, levofloxacin, teicoplanin and vancomycin. The most common risk factors for S. aureus carriage were being male, age ≤30 years, and nasal cavity cleaning habits.Colonization by S. aureus was greater among male and young age (20-30 years) students and those with irregularity nasal cleaning. The S. aureus isolates selected were revealed into various sequence types

Full Text available with Trip Pro

2017 Annals of Clinical Microbiology and Antimicrobials

40. Epidemiological, Clinical and Microbiological Characteristics of Patients with Post-Traumatic Osteomyelitis of Limb Fractures in Southwest China: A Hospital-Based Study (PubMed)

were monomicrobial, and 18 cases (21.43%) were polymicrobial. The infections were predominantly caused by Gram-positive bacteria (56, 53.85%). The most common Gram-positive bacteria were Staphylococcus aureus (39 cases, 37.50%) and S. epidermidis (6 cases, 5.77%), which were sensitive to ampicillin, synercid/ dalfopristin, linezolid, tigecycline, macrodantin, and vancomycin. S. aureus was the most common pathogen in both monomicrobial and polymicrobial cases. All 17 cases of MRSA infection were (...) sensitive to Imezolid, ampicillin, synercid/ dalfopristin, linezolid, tigecycline, furadantin, piperacillin/yaz, rifampicin, and vancomycin, respectively. The most common Gram-negative bacteria were E. coli (16 cases, 15.38%) and Enterobacter cloacae (11 cases, 10.58%), which were sensitive to thienamycin. Conclusions In this study, the overall rate of post-traumatic osteomyelitis of limb fractures (1.56%) is lower than the national average rate (2.6-7.8%), for major medical centers in China. The main

Full Text available with Trip Pro

2017 Journal of Bone and Joint Infection

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>