How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

3,589 results for

Q Fever

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

81. Management of Infants 0 to 60 days with Fever of Unknown Source

for clinicians, given the broad differential diagnosis. While viral infections remain the most common cause of fever in infants 0 to 60 days of age (Ishimine, 2007 [5]; Woll, 2018 [5a]), a systematic approach to evaluation is paramount in identifying infants at high risk for serious and invasive bacterial infections. Serious bacterial infections (SBI) are more prevalent in this population when compared with older children (Laupland, 2009 [5a]; Caviness, 2008b [5a]). The prevalence of SBI in febrile young (...) ) pleocytosis Neonates age 0 to 28 days: CSF white blood cell count =15/µL Infants 29 to 60 days CSF white blood cell count = 9 uL. Fever of uncertain source (FUS) An acute febrile illness in which the etiology of the fever is not apparent after a thorough history and physical exam Fever Temperature > 38ºC (100.4 ºF) Invasive bacterial infection (IBI) Bacteremia and/or bacterial meningitis in infants = 60 days of age Ill-appearing Infant described as: “toxic,” “limp,” “unresponsive,” “gray,” “cyanotic

2019 Cincinnati Children's Hospital Medical Center

82. Coverage of the 2011 Q Fever Vaccination Campaign in the Netherlands, Using Retrospective Population-Based Prevalence Estimation of Cardiovascular Risk-Conditions for Chronic Q Fever Full Text available with Trip Pro

Coverage of the 2011 Q Fever Vaccination Campaign in the Netherlands, Using Retrospective Population-Based Prevalence Estimation of Cardiovascular Risk-Conditions for Chronic Q Fever In 2011, a unique Q fever vaccination campaign targeted people at risk for chronic Q fever in the southeast of the Netherlands. General practitioners referred patients with defined cardiovascular risk-conditions (age >15 years). Prevalence rates of those risk-conditions were lacking, standing in the way of adequate (...) planning and coverage estimation. We aimed to obtain prevalence rates retrospectively in order to estimate coverage of the Q fever vaccination campaign.With broad search terms for these predefined risk-conditions, we extracted patient-records from a large longitudinal general-practice research-database in the Netherlands (IPCI-database). After validation of these records, obtained prevalence rates (stratified for age and sex) extrapolated to the Q fever high-incidence area population, gave

2015 PloS one

83. Q Fever

Q Fever Q Fever Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Q Fever Q Fever Aka: Q Fever , Coxiella Burnetii , Nine Mile Fever (...) ) Crit Dec Emerg Med 32(8): 3-12 Q Fever (Wikipedia) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Q Fever." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Coxiella burnetii (C0010240) Definition (NCI_CDISC) Any bacterial organism that can be assigned to the species Coxiella burnetii. Definition (NCI) A species of aerobic, Gram negative

2018 FP Notebook

84. Periodic fevers

Periodic fevers Periodic fevers ') Cookie Notice This site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our for more details. OK Menu Search Main navigation Utility navigation / Search navigation Search Search AAAAI Breadcrumb navigation ▸ ▸ Periodic fevers | Periodic fevers Q: 3/26/2020 I have 10 year-old white male with periodic fevers > 5 years. Extensive workup benign. Suspicion of PFAPA. His Fevers run 102-104 range and can last 7-14 days (...) . No arthralgias or conjunctivitis or rash during these episodes. Fevers don't respond to NSAID or Tylenol. I haven't tried Prednisone, Cimetidine or Singulair. Past Immune w/u normal: Normal CBC, Ig's, T & B cell panel; Neg. ANA/RF; Normal Complements; Normal Aldolase/CPK. He recently had right middle lobe pneumonia treated with Z pak and Cefdinir-RML PNA resolved. Repeat autoimmune workup during recent flare negative - CRP < 0.4. FHx benign. No FMF either. If he has another episode of pneumonia do sweat

2020 Publication 4891070

85. Epidemiology of Brucellosis, Q Fever and Rift Valley Fever at the Human and Livestock Interface in Northern Côte d'Ivoire. (Abstract)

Epidemiology of Brucellosis, Q Fever and Rift Valley Fever at the Human and Livestock Interface in Northern Côte d'Ivoire. Northern Côte d'Ivoire is the main livestock breeding zone and has the highest livestock cross-border movements in Côte d'Ivoire. The aim of this study was to provide updated epidemiological data on three neglected zoonotic diseases, namely brucellosis, Q Fever and Rift Valley Fever (RVF). We conducted three-stage cross-sectional cluster surveys in livestock and humans (...) of Brucella spp. in cattle adjusted for clustering was 4.6%. Cattle aged 5-8 years had higher odds of seropositivity (OR=3.5) than those aged ≤4years. The seropositivity in cattle was associated with having joint hygromas (OR=9), sharing the pastures with small ruminants (OR=5.8) and contact with pastoralist herds (OR=11.3). The seroprevalence of Q Fever was 13.9% in cattle, 9.4% in sheep and 12.4% in goats. The seroprevalence of RVF was 3.9% in cattle, 2.4% in sheep and 0% in goats. Seropositive ewes had

2016 Acta Tropica

86. Knowledge, Attitudes and Practices Towards Spotted Fever Group Rickettsioses and Q Fever in Laikipia and Maasai Mara, Kenya Full Text available with Trip Pro

about SFGR and 9.1% in Laikipia expressed good knowledge on Q fever and none in Maasai Mara. The diseases are not considered amongst potential causes of febrile illnesses in most medical facilities except in one facility in Laikipia. Majority of pastoralists practiced at least one predisposing activity for transmission of the diseases including consumption of raw milk, attending to parturition and sharing living accommodations with livestock. Education efforts to update knowledge on medical (...) Knowledge, Attitudes and Practices Towards Spotted Fever Group Rickettsioses and Q Fever in Laikipia and Maasai Mara, Kenya Many factors contribute to misdiagnosis and underreporting of infectious zoonotic diseases in most sub-Saharan Africa including limited diagnostic capacity and poor knowledge. We assessed the knowledge, practices and attitudes towards spotted fever group rickettsioses (SFGR) and Q fever amongst local residents in Laikipia and Maasai Mara in Kenya. A semi-structured

2016 Journal of public health in Africa

87. Q fever: risk of transmission via blood or other body material

Q fever: risk of transmission via blood or other body material Q fever: risk of transmission via blood or other body material Q fever: risk of transmission via blood or other body material Health Council of the Netherlands, Gezondheidsraad Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Health Council of the Netherlands, Gezondheidsraad. Q fever: risk (...) of transmission via blood or other body material. The Hague: Health Council of the Netherlands/Gezondheidsraad (GR). 2011/15E. 2011 Authors' conclusions At various points in this advisory report, the Committee notes there is a (relative) lack of data, not only on the potential transmission of Q fever via blood transfusion or body materials, but also regarding more basic questions. With regard to the latter, the Committee refers to the diagnosis and treatment of (primarily chronic) Q fever and the results

2011 Health Technology Assessment (HTA) Database.

88. Febrile patients admitted to remote hospitals in Northeastern Kenya: seroprevalence, risk factors and a clinical prediction tool for Q-Fever. Full Text available with Trip Pro

Febrile patients admitted to remote hospitals in Northeastern Kenya: seroprevalence, risk factors and a clinical prediction tool for Q-Fever. Q fever in Kenya is poorly reported and its surveillance is highly neglected. Standard empiric treatment for febrile patients admitted to hospitals is antimalarials or penicillin-based antibiotics, which have no activity against Coxiella burnetii. This study aimed to assess the seroprevalence and the predisposing risk factors for Q fever infection (...) ), abdominal pain (+0.8), respiratory tract infection (+1.0) and diarrhoea (-1.1).Q fever is common in febrile Kenyan patients but underappreciated as a cause of community-acquired febrile illness. The utility of Q fever score and screening patients for the risky social-economic and dietary practices can provide a valuable tool to clinicians in identifying patients to strongly consider for detailed Q fever investigation and follow up on admission, and making therapeutic decisions.

2016 BMC Infectious Diseases

89. First Identification and Description of Rickettsioses and Q Fever as Causes of Acute Febrile Illness in Nicaragua Full Text available with Trip Pro

First Identification and Description of Rickettsioses and Q Fever as Causes of Acute Febrile Illness in Nicaragua Rickettsial infections and Q fever present similarly to other acute febrile illnesses, but are infrequently diagnosed because of limited diagnostic tools. Despite sporadic reports, rickettsial infections and Q fever have not been prospectively studied in Central America.We enrolled consecutive patients presenting with undifferentiated fever in western Nicaragua and collected (...) epidemiologic and clinical data and acute and convalescent sera. We used ELISA for screening and paired sera to confirm acute (≥4-fold rise in titer) spotted fever and typhus group rickettsial infections and Q fever as well as past (stable titer) infections. Characteristics associated with both acute and past infection were assessed.We enrolled 825 patients and identified acute rickettsial infections and acute Q fever in 0.9% and 1.3%, respectively. Clinical features were non-specific and neither

2016 PLoS neglected tropical diseases

90. Q Fever Is Underestimated in the United States: A Comparison of Fatal Q Fever Cases from Two National Reporting Systems. Full Text available with Trip Pro

Q Fever Is Underestimated in the United States: A Comparison of Fatal Q Fever Cases from Two National Reporting Systems. Two national surveillance systems capturing reports of fatal Q fever were compared with obtained estimates of Q fever underreporting in the United States using capture-recapture methods. During 2000-2011, a total of 33 unique fatal Q fever cases were reported through case report forms submitted to the Centers for Disease Control and Prevention and through U.S. death (...) certificate data. A single case matched between both data sets, yielding an estimated 129 fatal cases (95% confidence interval [CI] = 62-1,250) during 2000-2011. Fatal cases of Q fever were underreported through case report forms by an estimated factor of 14 and through death certificates by an estimated factor of 5.2. © The American Society of Tropical Medicine and Hygiene.

2014 American Journal of Tropical Medicine & Hygiene

91. Estimated prevalence of chronic Q fever among Coxiella burnetii seropositive patients with an abdominal aortic/iliac aneurysm or aorto-iliac reconstruction after a large Dutch Q fever outbreak. (Abstract)

Estimated prevalence of chronic Q fever among Coxiella burnetii seropositive patients with an abdominal aortic/iliac aneurysm or aorto-iliac reconstruction after a large Dutch Q fever outbreak. The aim of this study was to estimate the seroprevalence of Q fever and prevalence of chronic Q fever in patients with abdominal aortic and/or iliac disease after the Q fever outbreak of 2007-2010 in the Netherlands.In November 2009, an ongoing screening program for Q fever was initiated. Patients (...) with abdominal aortic and/or iliac disease were screened for presence of IgM and IgG antibodies to phase I and II antigens of Coxiella burnetii using immunofluorescence assay and presence of C. burnetii DNA in sera and/or vascular wall tissue using polymerase chain reaction (PCR).A total of 770 patients with abdominal aortic and/or iliac disease were screened. Antibodies against C. burnetii were detected in 130 patients (16.9%), of which 40 (30.8%) patients showed a serological profile of chronic Q fever

2014 Journal of Infection

92. Comparison between Emerging Q Fever in French Guiana and Endemic Q fever in Marseille, France. Full Text available with Trip Pro

Comparison between Emerging Q Fever in French Guiana and Endemic Q fever in Marseille, France. Q fever is an emergent disease in French Guiana. We compared the incidence clinical and serologic profiles between patients from Cayenne, French Guiana and Marseille in metropolitan France during a four-year period. The annual incidence of diagnosed acute Q fever was significantly higher in Cayenne (17.5/100,000) than in Marseille (1.9/100,000) (P = 0.0004), but not the annual incidence (...) of endocarditis (1.29 versus 0.34/100,000). Most patients had fever (97%) and pneumonia (83%) in Cayenne versus 81% and 8% in Marseille (P < 0.0001 and P < 0.0001, respectively) but transaminitis was more common in patients from Marseille (54% versus 32%; P < 0.0001). The proportion of patients with cardiovascular infections was significantly lower in Cayenne (7%) than in Marseille (17%) (P = 0.017), although they showed a stronger immune response with higher levels of phase I IgG (P = 0.024). The differing

2014 American Journal of Tropical Medicine & Hygiene

93. Intact Interferon-γ response against Coxiella burnetii by peripheral blood mononuclear cells in chronic Q fever. Full Text available with Trip Pro

Intact Interferon-γ response against Coxiella burnetii by peripheral blood mononuclear cells in chronic Q fever. Q fever is caused by Coxiella burnetii, an intracellular bacterium that infects phagocytes. The aim of the present study was to investigate whether the C. burnetii-induced IFN-γ response is defective in chronic Q fever patients.IFN-γ was measured in supernatants of C. burnetii-stimulated peripheral blood mononuclear cells (PBMCs) of 17 chronic Q fever patients and 17 healthy (...) individuals. To assess IFN-γ responses, expression profiles of IFN-γ-induced genes in C. burnetii-stimulated PBMCs were studied in six patients and four healthy individuals. Neopterin was measured in PBMC supernatants (of eight patients and four healthy individuals) and in sera (of 21 patients and 11 healthy individuals). In a genetic association study, polymorphisms in genes involved in the Th1-cytokine response were analysed in a cohort of 139 chronic Q fever patients and a cohort of 220 control

2016 Clinical Microbiology and Infection

94. Molecular Identification of Q Fever in Patients with a Suspected Diagnosis of Dengue in Brazil in 2013-2014. Full Text available with Trip Pro

Molecular Identification of Q Fever in Patients with a Suspected Diagnosis of Dengue in Brazil in 2013-2014. Q fever is an important cause of undifferentiated fever that is rarely recognized or reported in Brazil. The objective of this study was to look for the presence of Coxiella burnetii during a dengue fever outbreak in the municipality of Itaboraí, Rio de Janeiro, Brazil, where this bacterium had previously infected humans and domesticated animals. Blood samples from clinically suspected (...) that awareness and knowledge of Q fever should be strengthened and that this bacterium is present in Brazil. Finally, because a negative molecular result does not completely rule out the diagnosis of Q fever and the serological assay based on seroconversion was not available, the actual number of this zoonosis is likely to be much higher than that reported in this study.© The American Society of Tropical Medicine and Hygiene.

2016 American Journal of Tropical Medicine & Hygiene

95. Endemic Q Fever in New South Wales, Australia: A Case Series (2005-2013). Full Text available with Trip Pro

Endemic Q Fever in New South Wales, Australia: A Case Series (2005-2013). Q fever is endemic in Australia, and during the period 2005-2013 our laboratory diagnosed 379 cases in New South Wales. To evaluate clinical symptoms, epidemiology, mode of diagnosis, antibody profiles, and treatment, a subset of 160 (42%) Q fever cases were analyzed in detail following the return of a questionnaire by the patient's doctor and from their laboratory reports. Overall, 82% patients were male (...) and predominantly middle aged. The majority of patients (89%) had animal contact among which 63% were with cattle, 11% with sheep, and 7% with kangaroos. Clinical symptoms were nonspecific: myalgia (94%), fever (91%), headache (80%), acute fatigue (64%), and arthralgia (55%). Most cases (93%) were acute, and serology (immunofluorescence) was the main diagnostic modality. Positive real-time polymerase chain reaction results were useful in the diagnosis of both acute and chronic Q fever, as was the isolation

2016 American Journal of Tropical Medicine & Hygiene

96. Lyophilization to improve the sensitivity of qPCR for bacterial DNA detection in serum: the Q fever paradigm. Full Text available with Trip Pro

Lyophilization to improve the sensitivity of qPCR for bacterial DNA detection in serum: the Q fever paradigm. Quantitative real-time PCR (qPCR) on serum provides significant added value to the diagnosis of Q fever, mainly at the acute stage of the disease in seronegative patients and in patients with endocarditis. We evaluated the benefits of Coxiella burnetii DNA concentration in serum by lyophilization to improve qPCR sensitivity. The detection limit of qPCR was determined by comparing six 10 (...) -fold dilutions of serum (calibrated with 104 bacteria ml-1) with and without lyophilization. We also tested, after lyophilization, 73 sera from patients with acute Q fever and 10 sera from patients with endocarditis for which specific qPCR for C. burnetii performed under our usual conditions remained negative. Lyophilization of DNA was found to improve sensitivity of the qPCR; the limit of detection of C. burnetii DNA by qPCR was 100-fold lower in lyophilized sera (1 bacterium ml-1) than in non

2016 Journal of Medical Microbiology

97. Seroprevalence of Q fever, Brucellosis, and Bluetongue in Selected Provinces in Lao People's Democratic Republic. Full Text available with Trip Pro

Seroprevalence of Q fever, Brucellosis, and Bluetongue in Selected Provinces in Lao People's Democratic Republic. This study has determined the proportional seropositivity of two zoonotic diseases, Q fever and brucellosis, and bluetongue virus (BTV) which is nonzoonotic, in five provinces of Lao People's Democratic Republic (PDR) (Loungphabang, Luangnumtha, Xayaboury, Xiengkhouang, and Champasak, and Vientiane Province and Vientiane capital). A total of 1,089 samples from buffalo, cattle, pigs (...) , and goats were tested, with seropositivity of BTV (96.7%), Q fever (1.2%), and brucellosis (0.3%). The results of this survey indicated that Q fever seropositivity is not widely distributed in Lao PDR; however, Xayaboury Province had a cluster of seropositive cattle in seven villages in four districts (Botan, Kenthao, Paklaiy, and Phiang) that share a border with Thailand. Further studies are required to determine if Xayaboury Province is indeed an epidemiological hot spot of Q fever activity

2016 American Journal of Tropical Medicine & Hygiene

98. Q Fever, Scrub Typhus, and Rickettsial Diseases in Children, Kenya, 2011-2012. Full Text available with Trip Pro

Q Fever, Scrub Typhus, and Rickettsial Diseases in Children, Kenya, 2011-2012. To increase knowledge of undifferentiated fevers in Kenya, we tested paired serum samples from febrile children in western Kenya for antibodies against pathogens increasingly recognized to cause febrile illness in Africa. Of patients assessed, 8.9%, 22.4%, 1.1%, and 3.6% had enhanced seroreactivity to Coxiella burnetii, spotted fever group rickettsiae, typhus group rickettsiae, and scrub typhus group orientiae

2016 Emerging Infectious Diseases

99. Altered interferon-γ response in patients with Q-fever fatigue syndrome. (Abstract)

Altered interferon-γ response in patients with Q-fever fatigue syndrome. Whether immunological mechanisms underlie Q-fever fatigue syndrome (QFS) remains unclear. For acute Q-fever, the antigen-specific interferon-γ (IFNγ) response may be a useful tool for diagnosis, and the IFNγ/interleukin(IL)-2 production ratio may be a marker for chronic Q-fever and treatment monitoring. Here we explored the specific IFNγ production and IFNγ/IL-2 ratio in QFS patients.IFNγ and IL-2 production were tested (...) in ex-vivo stimulated whole blood of QFS patients (n = 20), and compared to those previously determined in seropositive controls (n = 135), and chronic Q-fever patients (n = 28). Also, the correlation between patient characteristics and IFNγ, IL-2, and IFNγ/IL-2 ratio was determined.QFS patients were younger (p < 0.001), but gender distribution was similar to seropositive controls and chronic Q-fever patients. Coxiella burnetii Nine Mile stimulation revealed a higher IFNγ production in QFS (median

2016 Journal of Infection

100. Chronic Q Fever in Alberta: A Case of Coxiella burnetii Mycotic Aneurysm and Concomitant Vertebral Osteomyelitis Full Text available with Trip Pro

Chronic Q Fever in Alberta: A Case of Coxiella burnetii Mycotic Aneurysm and Concomitant Vertebral Osteomyelitis Chronic Q fever is a potentially life-threatening infection from the intracellular, Gram-negative Coxiella burnetii. It presents most commonly as endocarditis or vascular infection in people with underlying cardiac or vascular disease. We discuss a case of a 67-year-old male with Coxiella burnetii vascular infection of a perirenal abdominal aortic graft. The patient had a history (...) of an abdominal aortic aneurysm (AAA) repair 5 years earlier. He presented with a 12 × 6 × 8 cm perirenal pseudoaneurysm and concomitant L1, L2, and L3 vertebral body discitis. He underwent an open repair which revealed a grossly infected graft perioperatively. Q fever serology revealed phase I serological IgG titer of 1 : 2048 and phase II 1 : 1024 consistent with chronic Q fever. Polymerase chain reaction (PCR) on infected vascular tissue was positive for C. burnetii. The patient was started on doxycycline

2016 The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>