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Q Fever

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3001. Iodine

including swelling of the lips and face (angioedema), severe bleeding and bruising, fever, joint pain, lymph node enlargement, hives, and death. However, such sensitivity is very rare. Large amounts or long-term use of iodine are POSSIBLY UNSAFE . Adults should avoid prolonged use of doses higher than 1100 mcg per day (the upper tolerable limit, UL) without proper medical supervision. In children, doses should not exceed 200 mcg per day for children 1 to 3 years old, 300 mcg per day for children 4 to 8 (...) of children born after salt iodization intervention in IDD areas]. Zhong Guo Di Fang Bing Xue Za Zhi (Chinese) 1991;10(Suppl):13-16. Fu, L. X., Zeng, Q. Z., Deng, l. Q., and Chen, Q. F. The effect of prevention of iodised salt on intelligency and physical development in endimic critinism of Changping of Guangdong. Symposium of the Third Chinese Endemic Goiter and Cretinism (Chinese) 1987;:155. Wang, H., Shi, F. K., Li, K. D., and Wang, D. [A survey report of intelligence of children born after and before

2009 National Centre for Complementary and Alternative Medicine

3002. Lycium

and exercising alone. But drinking the juice doesn't further improve weight or body fat. Blood circulation problems . Cancer . Dizziness . Fever . High blood pressure . Malaria . Ringing in the ears (tinnitus) . Sexual problems (impotence) . Other conditions . More evidence is needed to rate the effectiveness of goji for these uses. How does it work? Goji contains chemicals that might help lower blood pressure and blood sugar. Goji might also help stimulate the immune system and protect organs from oxidative (...) minerals and Himalayan actives. J.Cosmet.Dermatol. 2012;11:183-192. . Paul Hsu, C. H., Nance, D. M., and Amagase, H. A meta-analysis of clinical improvements of general well-being by a standardized Lycium barbarum. J.Med.Food 2012;15:1006-1014. . Franco, M., Monmany, J., Domingo, P., and Turbau, M. [Autoimmune hepatitis triggered by consumption of Goji berries]. Med.Clin.(Barc.) 9-22-2012;139:320-321. . Vidal, K., Bucheli, P., Gao, Q., Moulin, J., Shen, L. S., Wang, J., Blum, S., and Benyacoub, J

2009 National Centre for Complementary and Alternative Medicine

3003. Beta-Carotene

or swelling and ulcers that occur inside the mouth. It is also taken by mouth to prevent the development of new moles on the skin, death due to long-term liver disease, a disease called amyotrophic lateral sclerosis (ALS), and the enlargement of a blood vessel located near the abdomen (abdominal aneurysm). Beta-carotene is also in used in malnourished (underfed) women to reduce the chance of death and night blindness during pregnancy, as well as diarrhea and fever after giving birth. Some people take beta (...) -carotene seems decrease the risk of breast cancer in pre-menopausal women who are at high risk of getting breast cancer. These include women with a family history of breast cancer and those who use alcohol excessively. Preventing complications post-childbirth . Taking beta-carotene by mouth before, during, and after pregnancy seems to reduce the incidence of diarrhea and fever after childbirth. Pregnancy-related complications . Taking beta-carotene by mouth seems to reduce the risk of pregnancy-related

2009 National Centre for Complementary and Alternative Medicine

3004. Eucalyptus

. Bleeding gums . Bladder diseases . Diabetes . Fever . Flu . Liver and gallbladder problems . Loss of appetite . Other conditions . More evidence is needed to rate the effectiveness of eucalyptus for these uses. How does it work? Eucalyptus leaf contains chemicals that might help control blood sugar. It also contains chemicals that might have activity against bacteria and fungi. Eucalyptus oil contains chemicals that might help pain and inflammation. It might also block chemicals that cause asthma (...) directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Other names Blue Gum, Blue Mallee, Blue Mallee Oil, Eucalipto, Eucalypti Folium, Eucalyptol, Eucalyptol Oil, Eucalyptus blatter, Eucalyptus bicostata, Eucalyptus Essential Oil, Eucalyptus Oil, Eucalyptus fructicetorum, Eucalyptus globulus, Eucalyptus Leaf, Eucalyptus odorata, Eucalyptus Oil, Eucalyptus polybractea, Eucalyptus smithii, Fever Tree, Fieberbaumblatter, Gully Gum, Gully Gum Oil

2009 National Centre for Complementary and Alternative Medicine

3005. tetracyclines

than by antibacterial activity. They still remain the antibiotics of choice in the treatment of infections due to:- chlamydia - Trachoma, psittacosis, salpingitis, urethritis and lymphogranuloma venereum rickettsia - Q-fever mycoplasma brucella borrelia burgdorferi - Lyme disease Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted

2010 GP Notebook

3006. Coxiella burnetti pneumonia

Coxiella burnetti pneumonia Coxiella burnetti pneumonia - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Coxiella burnetti pneumonia Q fever is a form of atypical pneumonia caused by the rickettsia-like organism Coxiella burnetti. The name originates from the term 'query' fever which was applied to the disease when first seen in abattoir workers in Australia. It accounts for less than 1% of pneumonias in the UK. Compared

2010 GP Notebook

3007. pneumonia (coxiella)

pneumonia (coxiella) pneumonia (coxiella) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search pneumonia (coxiella) Q fever is a form of atypical pneumonia caused by the rickettsia-like organism Coxiella burnetti. The name originates from the term 'query' fever which was applied to the disease when first seen in abattoir workers in Australia. It accounts for less than 1% of pneumonias in the UK. Compared to other rickettsias

2010 GP Notebook

3008. Canadian best practice recommendations for stroke care

, hyperglycemia, fever and dehydration; and, c) ongoing rehabilitation policies (coordinated interdisciplinary team care, early assessment of needs after discharge). The Stroke Unit Trialists’ systematic review includ ed 23 randomized and quasi-randomized trials containing outcome information

2008 CPG Infobase

3009. Statement on personal protective measures to prevent arthropod bites

on blades of grasses or branches of low bushes for passing hosts. A few species also live indoors. Fleas Typhus Plague Bartonellosis Tularemia Q-fever Found indoors and outdoors, often associated with a specific type of host, but will feed on a variety of mammals (including humans). Body lice Relapsing fever (borreliosis) Rickettsioses Typhus Usually found in clothing, except when feeding on human host. Sand flies ( Phlebotomus, Lutzomia ) Leishmaniasis Sand fly fever Bartonellosis Usually bite at night (...) decreases the risk for others, because peak seasonality for transmitting ) Vector Disease caused and pathogen(s) transmitted Peak Biting Time/Activity Anopheles mosquitos Malaria Filariasis Usually bite between sunset and sunrise. Peak biting hours may vary. Some species prefer to bite indoors, while others prefer outdoors. Aedes mosquitos Yellow fever Dengue fever Filariasis Usually bite during daylight hours, often outside, but some important vectors bite inside. Culex mosquitos Filariasis Japanese

2005 CPG Infobase

3010. Bendamustine (Treanda)

Established Name bendamustine Trade Name Treanda ® Therapeutic Class Alkylating Agent Applicant Cephalon Priority Designation S Formulation I.V. Dosing Regimen 120 mg/m 2 , days 1 & 2, q 21 days Indication Rituximab-Refractory, Indolent NHL Intended Population Patients with indolent NHL Clinical Review, Division of Drug Oncology Products Virginia Kwitkowski NDA 22-303 /bendamustine (Treanda) 2 Table of Contents 1 Recommendations/Risk Benefit Analysis 10 1.1 Recommendation on Regulatory Action 10 1.2 Risk (...) of pentostatin and fludarabine due to the risk of severe pulmonary toxicity. Cladribine: The product label contains a contraindication for concomitant use of alkylating agents, antimetabolites, and live vaccines. Frequent AEs: Anorexia, Bone Marrow Depression, Fatigue, Fever, Headache Disorder, Infection, Nausea, Neutropenic Disorder, Severe Anemia, Skin Rash, Thrombocytopenic Disorder, and Vomiting. Rare: MDS, nephrotoxicity, and neuropathy. Alkylating Agents Alkylating agents can cause severe

2007 FDA - Drug Approval Package

3012. Posaconazole (NoxafilR)

reactions were consistent with the underlying medical conditions. Most conlnlon events included fever, nausea, diarrhea and hypokalemia and occurred at similar frequency in posaconazole-treated and comparator-treated patients. Noteworthy adverse events included hepatic NDA 22-003 NoxafilB (posaconazole) prophylaxis of invasive Aspergillus and Calidida infections toxicity and the cyclosporine drug interaction. There were cases of thrombocytopenia, TTPJHUS, and pulmonary embolism that were included

2006 FDA - Drug Approval Package

3013. Pain Management Options During Labour

include: • firm sacral pressure • effleurage • shoulder, back, foot massage 2.4 HYDROTHERAPY & THERMAL THERAPY Deep water immersion during the first stage of labour is associated with a significant reduction Pain Management Options during Labour October 2007 Page 8 of 29 in both pain scores and regional analgesia without affecting operative birth rates or neonatal outcomes including Apgar scores, NICU admissions, and infection. 7 Women can spend long periods of time in the tub. Hyperthermia (...) the risk benefit ratio of regional anesthesia has to be considered on an individual basis. 38 Pain Management Options during Labour October 2007 Page 19 of 29 D. Risks / Side Effects • hypotension (less common now when low dose solutions are used) • dural puncture and spinal headache • failed block, unilateral or patchy block (10-15%) most common • pruritis • maternal fever • higher likelihood of requiring an assisted vaginal delivery in nulliparous women • catheter migration either subarachnoid

2007 British Columbia Perinatal Health Program

3014. Fetal Health Surveillance: Antepartum & Intrapartum Consensus Guideline

frequency of auscultation First stage–latent phase First stage–active phase Active second stage For the latent phase of labour, there are very limited data on which to base a recommendation for IA. Optimally, most women will be in their own home environment with family support during this period but may be in hospital because of geographic /weather considerations. SOCG* Recommended at the time of assessment, approximately q1h q 15–30 minutes q 5 minutes ACOG q 15 minutes q 5 minutes AWHONN q 15–30 (...) minutes q 5–15 minutes RCOG q 15 minutes q 5 minutes *Society of Obstetricians and Gynecologists of Canada, 2007 American College of Obstetricians and Gynecologists, 2005 Association of Women’s Health, Obstetric and Neonatal Nurses ; Feinstein, Sprague, & Trepanier, 2000 166 Royal College of Obstetricians and Gynaecologists, 2001 7 SOGC Clinical Tip The FHR should be assessed regularly to ensure that it is in the same range after the contraction as it was in the previous assessments. If not, assess

2008 British Columbia Perinatal Health Program

3015. National data elements for the clinical management of acute coronary syndromes Full Text available with Trip Pro

Number of distinct episodes of anginal pain that occurred in the 24 hours before hospital presentation. RS NC Secondary cause of angina Identifies the secondary factor such as fever, anaemia, hypoxaemia, tachycardia, thyrotoxicosis, or severe valvular disease. RS C Heart rate The heart rate recorded in beats per minute (at presentation). RS C Blood pressure: diastolic, measured The person’s measured diastolic blood pressure. RS C Blood pressure: systolic, measured The person’s measured systolic blood (...) abnormalities are located on the 12-lead ECG. RS C ECG abnormalities: type Describes the type of abnormalities seen on the ECG. RS NC ST elevation in lead V4R of the ECG The presence of ST-segment elevation greater than or equal to 1 mm (0.1 mV) in lead V4R when right-sided precordial leads are recorded. RS NC Follow-up ECG: new Q waves The presence of new Q waves in a follow-up ECG recorded at least 6 hours after the initial ECG. The new Q waves are greater than or equal to 0.03 seconds in width

2005 MJA Clinical Guidelines

3017. Point-of-Care influenza diagnostic tests

including fever (38-40° lasting between 1-5 days), chills, sore throat, headache, myalgias, malaise, anorexia and fatigue. Photophobia, abdominal pain and diarrhoea are less common symptoms. Most cases of influenza are self limiting. Infection rates are usually highest in children and complications of infection in this patient group may include febrile seizures. However serious complication rates such as the development of pneumonia are highest in the elderly. This is usually due to the presence (...) and Research Limited 2007; Lopez & Huang 2007). Stage of development Several of the rapid POCT influenza diagnostic kits are available and in use in Australia including the Binax FluNow, the Directigen and the QuickVue kits (personal correspondence). Currently, these kits are not required to be listed on the Australian Register of Therapeutic Goods. POCT for influenza is likely to 3 Influenza-like illness: acute upper respiratory tract infection characterised by abrupt onset and two of the following: fever

2008 Australia and New Zealand Horizon Scanning Network

3018. Molecular adsorbents recirculating system - MARS

(%) Deterioration in clinical condition 1/12 (8.3) 0/4 (0) anaemia 6/12 (50) 3/4 (75) haemorrhage 1/12 (8.3) 1/4 (25) hypotension 0/12 (0) 2/4 (50) coagulopathy 3/12 (25) 0/4 (0) disorientation 1/12 (8.3) 0/4 (0) dyspnea 1/12 (8.3) 0/4 (0) arterial puncture 1/12 (8.3) 0/4 (0) fever/sepsis 2/12 (16.6) 0/4 (0) parathesia 1/12 (8.3) 0/4 (0) Adverse events associated with end stage liver disease Event MARS ® (%) Control (%) Deterioration in HE 0/12 (0) 3/12 (25) hypotension 2/12 (16.6) 3/12 (25) worsening renal (...) Population Outcomes Khuroo et al (2004) I Systematic review of RCTs Study included data from 4 RCTs (n=67 patients) and 2 non- randomised trials (n=61 patients). RCTs Control group mortality rate in meta-analysis 12/31 (38.7%) MARS ® group mortality rate in meta-analysis 12/36 (33.3%) Pooled RR=0.56, 95%CI [0.28, 1.14] Absolute risk difference = 5.3% NNTB = 19 [NNTB 4 to 8 to NNTH 6] Cochran Q test for heterogeneity NS (p=0.39) therefore trials for this endpoint were homogenous. No publication bias (p

2006 Australia and New Zealand Horizon Scanning Network

3019. MRI guided high intesity focused ultrasound

be monitored in 12 months time. SOURCES OF FURTHER INFORMATION: AIHW (2007). AIHW National Hospital Morbidity Database [Internet]. Australian Institute of Health and Welfare. Available from: http://www.aihw.gov.au/cognos/cgi- bin/ppdscgi?DC=Q&E=/ahs/principaldiagnosis9899-0405 [Accessed 2nd April 2007]. ANZHSN (2006). Sonablate 500 system for prostate cancer, Medical Services Advisory Committee, Canberra, http://www.horizonscanning.gov.au/internet/horizon/publishing.nsf/Content/2E6BEDBA8F53 (...) experience with magnetic resonance imaging-guided focused ultrasound', Mayo Clinic Proceedings, 81 (7), 936-942 Hynynen, K. & MacDannold, N. (2004). 'MRI guided and monitored focused ultrasound thermal ablation methods: A review of progress', International Journal of Hyperthermia, 20 (7), 725-737 InSightec Ltd (2007). EXABLATE - Non-Invasive Treatment for Uterine Fibroids [Internet]. InSightec Ltd. Available from: http://www.exablate.net/html/index.htm [Accessed 2nd April 2007]. MSAC (2006). Uterine

2007 Australia and New Zealand Horizon Scanning Network

3020. MRI - guided high intensity utrasound - uterine fibroids

Ltd ADG: Class: Class IIb Product Id: 212416 Product Name: Hyperthermia system, ultrasound. In addition MRgFUS has been approved in the following countries: United States, UK, Germany, France, Canada, Mexico, Brazil, Russia, Korea, Taiwan and Singapore. 2008 DIFFUSION The Royal Woman's Hospital, Melbourne, Australia, has purchased a 3T MRI and ExAblate 2000 with uterine fibroids application. The MRI will be installed at the beginning of September 2008 and the ExAblate will be installed late (...) at night MRgFUS for uterine fibroids: April 2007 6 SOURCES OF FURTHER INFORMATION: AIHW (2007). AIHW National Hospital Morbidity Database [Internet]. Australian Institute of Health and Welfare. Available from: http://www.aihw.gov.au/cognos/cgi- bin/ppdscgi?DC=Q&E=/ahs/principaldiagnosis9899-0405 [Accessed 2nd April 2007]. ANZHSN (2006). Sonablate 500 system for prostate cancer, Medical Services Advisory Committee, Canberra, http://www.horizonscanning.gov.au/internet/horizon/publishing.nsf/Content

2008 Australia and New Zealand Horizon Scanning Network

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