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121. Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. (Abstract)

Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. Medical studies have suggested that buffering local anesthetic may increase the ability to achieve anesthesia. The purpose of this study was to determine the effect of 4% buffered lidocaine on the anesthetic success of the inferior alveolar nerve (IAN) block in patients experiencing symptomatic irreversible (...) pulpitis.One hundred emergency patients diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received a conventional IAN block using either 2.8 mL 4% lidocaine with 1:100,000 epinephrine or 2.8 mL 4% lidocaine with 1:100,000 epinephrine buffered with sodium bicarbonate in a double-blind manner. For the buffered solution, each cartridge was buffered with 8.4% sodium bicarbonate using the OnPharma (Los Gatos, CA) system to produce a final concentration of 0.18 mEq/mL

2015 Journal of Endodontics Controlled trial quality: uncertain

122. Efficacy of mepivacaine-tramadol combination on the success of inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis: a randomized clinical trial. (Abstract)

Efficacy of mepivacaine-tramadol combination on the success of inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis: a randomized clinical trial. To compare the success of an inferior alveolar nerve block (IANB) after injecting a combination of mepivacaine and tramadol or mepivacaine alone in patients with symptomatic irreversible pulpitis (SIP) in mandibular permanent molars.This study was a double-blind, randomized, controlled clinical trial. Two study groups were

2015 International endodontic journal Controlled trial quality: uncertain

123. A Comparison of Different Volumes of Articaine for Inferior Alveolar Nerve Block for Molar Teeth with Symptomatic Irreversible Pulpitis. Full Text available with Trip Pro

A Comparison of Different Volumes of Articaine for Inferior Alveolar Nerve Block for Molar Teeth with Symptomatic Irreversible Pulpitis. Achieving anesthesia in mandibular molar teeth with irreversible pulpitis is very difficult. The aim of this study was to compare the efficacy of 1.8 mL and 3.6 mL articaine for an inferior alveolar nerve block (IANB) when treating molars with symptomatic irreversible pulpitis.In a randomized, double-blind clinical trial, 82 first mandibular molar teeth (...) with symptomatic irreversible pulpitis randomly received conventional IANB injection either with 1 (1.8 mL) or 2 cartridges (3.6 mL) of 4% articaine with 1:100,000 epinephrine. The patients recorded their pain before and during access cavity preparation as well as during root canal instrumentation using a Heft-Parker visual analog scale. No or mild pain was considered as successful anesthesia. Data were analyzed by t and chi-square tests.Eighty patients were eligible to participate in this study, which showed

2015 Journal of Endodontics Controlled trial quality: uncertain

124. Advanced Caries Microbiota in Teeth with Irreversible Pulpitis. (Abstract)

Advanced Caries Microbiota in Teeth with Irreversible Pulpitis. Bacterial taxa in the forefront of caries biofilms are candidate pathogens for irreversible pulpitis and are possibly the first ones to invade the pulp and initiate endodontic infection. This study examined the microbiota of the most advanced layers of dentinal caries in teeth with irreversible pulpitis.DNA extracted from samples taken from deep dentinal caries associated with pulp exposures was analyzed for the presence (...) and lactobacilli were very prevalent but comprised only 0.09% and 2% of the whole bacterial population, respectively.Several bacterial taxa were found in advanced caries lesions in teeth with exposed pulps, and some of them were significantly associated with symptoms. A role for these taxa in the etiology of irreversible pulpitis is suspected.Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

2015 Journal of Endodontics

125. The Effect of Acupuncture on the Success of Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis: A Triple-blind Randomized Clinical Trial. (Abstract)

The Effect of Acupuncture on the Success of Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis: A Triple-blind Randomized Clinical Trial. An inferior alveolar nerve block (IANB) does not always provide satisfactory anesthesia for patients with irreversible pulpitis. The aim of this study was to assess the effect of preoperative acupuncture on the success rate of IANBs for teeth with symptomatic irreversible pulpitis.In a randomized triple-blinded clinical trial, 40 (...) patients with symptomatic irreversible pulpitis were divided into 2 groups: the acupuncture and control groups. In the acupuncture group, a disposable needle was inserted at LI4 (Hegu) acupoint, and after 15 minutes, for patients who had reported the De qi sensation, an IANB was administered. In the control group, 15 minutes before the administration of an IANB, the practitioner simply imitated the acupuncture procedure but did not actually insert the needle. Endodontic treatments were conducted

2015 Journal of Endodontics Controlled trial quality: uncertain

126. A Combination of Acetaminophen/Hydrocodone may not Affect Cold Pulpal Testing in Patients With Symptomatic Irreversible Pulpitis. (Abstract)

A Combination of Acetaminophen/Hydrocodone may not Affect Cold Pulpal Testing in Patients With Symptomatic Irreversible Pulpitis. 25987386 2016 08 24 2018 12 02 1532-3390 15 2 2015 Jun The journal of evidence-based dental practice J Evid Based Dent Pract A Combination of Acetaminophen/Hydrocodone may not Affect Cold Pulpal Testing in Patients With Symptomatic Irreversible Pulpitis. 66-7 10.1016/j.jebdp.2015.03.004 S1532-3382(15)00036-6 Williamson Anne E AE Diplomate, American Board (...) of Endodontics, Associate Professor, Department of Endodontics, Director, Advanced Education in Endodontics, W 341 DSB, University of Iowa, Iowa City, IA 52242, USA, Tel.: +1 319 335 7471. eng Journal Article Comment 2015 03 28 United States J Evid Based Dent Pract 101083101 1532-3382 362O9ITL9D Acetaminophen 6YKS4Y3WQ7 Hydrocodone D IM J Endod. 2014 Dec;40(12):1958-60 25442725 Acetaminophen Double-Blind Method Humans Hydrocodone Mandibular Nerve Pulpitis 2015 5 20 6 0 2015 5 20 6 0 2016 8 25 6 0 ppublish

2015 Journal of Evidence Based Dental Practice

127. Anesthetic efficacy of meperidine in teeth with symptomatic irreversible pulpitis. Full Text available with Trip Pro

Anesthetic efficacy of meperidine in teeth with symptomatic irreversible pulpitis. Achieving adequate pulpal anesthesia in mandibular teeth is always a challenge. Supplementary injections and using drugs in combination are some methods implemented to overcome this hurdle. In this randomized clinical trial, use of meperidine in conjunction with lidocaine in intraligamentary injection did not exhibit significant improvement in anesthesia.

2015 Anesthesia progress Controlled trial quality: uncertain

128. Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpitis

Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpitis Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpiti Search National Elf Service Search National Elf Service » » » » Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpitis Jan 20 2014 Posted by Irreversible pulpitis often presents as an acute and intense pain and is a frequent reason (...) for emergency dental visits. Treatment involves accessing the root canal of the tooth to remove the inflamed pulp (nerve) and cleaning the root canal. The aim of this review was to assess the effects of systemic antibiotics for irreversible pulpitis. The usual Cochrane approaches were taken with Searches being conducted in the Cochrane Oral Health Group’s Trials Register; the Cochrane Central Register of Controlled Trials (CENTRAL); Medline; Embase and the US National Institutes of Health Trials Register

2014 The Dental Elf

129. [Clinical trail on the effect of nitrous oxide/oxygen inhalation sedation on the treatment of acute pulpitis]. (Abstract)

[Clinical trail on the effect of nitrous oxide/oxygen inhalation sedation on the treatment of acute pulpitis]. To evaluate the effectiveness and safety of nitrous oxide/oxygen inhalation sedation in the treatment of acute pulpitis.The study population comprised 72 patients of acute pulpitis treated from September 2012 to March 2013. They were randomly divided into 2 groups, which included experimental group (37 cases) and control group (35 cases). Venham clinical anxiety, cooperative behavior (...) ).The technique of nitrous oxide/oxygen inhalation sedation provides a safe and effective way to release pain and anxiety during treatment of acute pulpitis, while the long-term clinical result still needs further investigation.

2014 Shanghai kou qiang yi xue = Shanghai journal of stomatology Controlled trial quality: uncertain

130. Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. (Abstract)

Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis.One hundred emergency patients in moderate to severe pain (...) diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received, in a double-blind manner, identical capsules of either a combination of 1000 mg acetaminophen/10 hydrocodone or placebo. Cold testing with Endo-Ice (1,1,1,2 tetrafluoroethane; Hygenic Corp, Akron, OH) was performed at baseline and every 10 minutes for 60 minutes. Pain to cold testing was recorded by the patient using a Heft-Parker visual analog scale. Patients' reaction to the cold application was also

2014 Journal of Endodontics Controlled trial quality: uncertain

131. The effect of adding fentanyl to epinephrine-containing lidocaine on the anesthesia of maxillary teeth with irreversible pulpitis: a randomized clinical trial. Full Text available with Trip Pro

The effect of adding fentanyl to epinephrine-containing lidocaine on the anesthesia of maxillary teeth with irreversible pulpitis: a randomized clinical trial. Deep and long-lasting anesthesia is essential throughout endodontic treatment. This study was conducted to compare the effect of adding fentanyl to epinephrine-containing lidocaine on depth and duration of local anesthesia in painful maxillary molars with irreversible pulpitis (IRP).This randomized double-blind, clinical trial

2014 Iranian endodontic journal Controlled trial quality: uncertain

132. Insufficient evidence to assess the effectiveness of antibiotics for irreversible pulpitis. (Abstract)

Insufficient evidence to assess the effectiveness of antibiotics for irreversible pulpitis. The Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase and the US National Institutes of Health Trials Register.Randomised controlled trials (RCTs) which compared pain relief with systemic antibiotics and analgesics, against placebo and analgesics in the acute preoperative phase of irreversible pulpitis.Study selection, risk of bias (...) trials that can provide additional evidence as to whether antibiotics, prescribed in the preoperative phase, can affect treatment outcomes for irreversible pulpitis.

2014 Evidence Based Dentistry

133. Down-regulation of Inflammatory Mediator Synthesis and Infiltration of Inflammatory Cells by MMP-3 in Experimentally Induced Rat Pulpitis. (Abstract)

Down-regulation of Inflammatory Mediator Synthesis and Infiltration of Inflammatory Cells by MMP-3 in Experimentally Induced Rat Pulpitis. Matrix metalloproteinase (MMP)-3 is a member of the MMP family that degrades the extracellular matrix. Application of MMP-3 to injured pulp tissue induces angiogenesis and wound healing, but its anti-inflammatory effects are still unclear. Here, we evaluated the anti-inflammatory functions of MMP-3 in vitro and in vivo.Nitric oxide and inflammatory mediator (...) pulpitis induced by the application of LPS for 9 hours in the presence or absence of MMP-3.NO and pro-inflammatory mediator synthesis promoted by LPS was significantly down-regulated by MMP-3 in vitro. The full length of mMmp3 down-regulated the LPS-induced NO synthesis and chemical mediator mRNA expression, however the mMmp3 missing the signal peptide failed to block the NO synthesis induced by LPS. The numbers of major histocompatibility complex class II+ and CD68+ cells, which infiltrated

2014 Journal of Endodontics

134. Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis

Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02110966 Recruitment Status : Completed First Posted : April 10, 2014 Last Update Posted

2014 Clinical Trials

135. Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02226913 Recruitment Status : Completed First Posted : August 27, 2014

2014 Clinical Trials

136. Effect of long acting local anesthetic on postoperative pain in teeth with irreversible pulpitis: Randomized clinical trial. Full Text available with Trip Pro

Effect of long acting local anesthetic on postoperative pain in teeth with irreversible pulpitis: Randomized clinical trial. The objective of this study was to compare the effect of long acting anesthetics on postoperative pain in teeth with irreversible pulpitis.Forty patients were randomly assigned into two groups of twenty patients each. Each patient who fit the inclusion criteria was administered local anesthesia before undergoing root canal treatment. The anesthetic solution was either 2 (...) ) but had significantly decreased pain by 24 h compared to the bupivacaine group patients who had significantly lower postoperative pain levels at 6 and 12 h.The use of long acting local anesthetic can significantly reduce the postoperative pain in teeth with irreversible pulpitis.

2014 Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society Controlled trial quality: uncertain

137. Comparison between Prescription of Regular or On-demand Ibuprofen on Postoperative Pain after Single-visit Root Canal Treatment of Teeth with Irreversible Pulpitis. (Abstract)

Comparison between Prescription of Regular or On-demand Ibuprofen on Postoperative Pain after Single-visit Root Canal Treatment of Teeth with Irreversible Pulpitis. Pain management is very important in endodontic practice. The aim of this study was to compare the effect on pain relief of on-demand versus regular prescription of ibuprofen after single-visit root canal treatment in teeth with irreversible pulpitis.Sixty mandibular and maxillary molar teeth with irreversible pulpitis without (...) medication compared with patients in group 1 (P = .04).In patients who had irreversible pulpitis with no moderate to severe spontaneous pain, prescribing ibuprofen on a regular basis after root canal treatment had no significant effect on pain relief compared with an on-demand regimen up to 48 hours after treatment.Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

2014 Journal of Endodontics Controlled trial quality: uncertain

138. Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. (Abstract)

Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of the combination acetaminophen/hydrocodone on the anesthetic success of mandibular posterior teeth in patients experiencing symptomatic (...) irreversible pulpitis.One hundred emergency patients in moderate to severe pain diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received, in a double-blind manner, identical capsules of either a combination dose of 1000 mg acetaminophen/10 mg hydrocodone or placebo 60 minutes before the administration of a conventional inferior alveolar nerve (IAN) block. Endodontic access was begun 15 minutes after completion of the block, and all patients used for data analysis

2014 Journal of Endodontics Controlled trial quality: predicted high

139. Efficacy of supplementary buccal infiltrations and intraligamentary injections to inferior alveolar nerve blocks in mandibular first molars with asymptomatic irreversible pulpitis: a randomized controlled trial. (Abstract)

Efficacy of supplementary buccal infiltrations and intraligamentary injections to inferior alveolar nerve blocks in mandibular first molars with asymptomatic irreversible pulpitis: a randomized controlled trial. This randomized double-blinded controlled trial was performed to compare the efficacy of inferior alveolar nerve block (IANB) injection for mandibular first molar teeth with irreversible pulpitis with or without supplementary buccal infiltration and intraligamentary injection.Eighty-two (...) patients with asymptomatic irreversible pulpitis received either a combination of intraligamentary injection + buccal infiltration+ IANB or with traditional IANB injection in mandibular first molar teeth with irreversible pulpitis. Each patient recorded their pain score on a Heft-Parker visual analogue scale before commencing treatment, in response to a cold test 15 min after the designated anaesthetic injection, during access cavity preparation and during root canal instrumentation. No or mild pain

2014 International endodontic journal Controlled trial quality: uncertain

140. Two-year results of vital pulp therapy in permanent molars with irreversible pulpitis: an ongoing multicenter randomized clinical trial. (Abstract)

Two-year results of vital pulp therapy in permanent molars with irreversible pulpitis: an ongoing multicenter randomized clinical trial. Oral healthcare expenses are increasing rapidly as a result of the growth of high-cost health technologies worldwide. In many developing/developed countries, low-cost tooth extraction is the alternative treatment option for a high-cost root canal therapy (RCT) for management of human molars with irreversible pulpitis. Vital pulp therapy with calcium-enriched (...) for endodontic treatment of permanent molar teeth with irreversible pulpitis and can be recommended for general clinical practice.

2014 Clinical oral investigations Controlled trial quality: uncertain

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