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41. Articaine (4%) Does Not Improve Inferior Alveolar Nerve Block Success Compared to Lidocaine (2%) for Mandibular Molars with Irreversible Pulpitis

Articaine (4%) Does Not Improve Inferior Alveolar Nerve Block Success Compared to Lidocaine (2%) for Mandibular Molars with Irreversible Pulpitis UTCAT2658, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Articaine (4%) Does Not Improve Inferior Alveolar Nerve Block Success Compared to Lidocaine (2%) for Mandibular Molars with Irreversible Pulpitis Clinical Question For patients with irreversible pulpitis in mandibular (...) molars, is 4% articaine superior to 2% lidocaine in achieving successful anesthesia when administered as an inferior alveolar nerve block? Clinical Bottom Line Administration of 4% articaine as an inferior alveolar nerve (IAN) block does not result in greater anesthesia success compared to 2% lidocaine when providing endodontic treatment to mandibular molars diagnosed with irreversible pulpitis. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient

2014 UTHSCSA Dental School CAT Library

42. Pre-operative analgesia for patients with pulpitis improved anaesthetic success

Pre-operative analgesia for patients with pulpitis improved anaesthetic success Pre-operative analgesia for patients with pulpitis improved anaesthetic success - National Elf Service Search National Elf Service Search National Elf Service » » » » Pre-operative analgesia for patients with pulpitis improved anaesthetic success Jan 25 2017 Posted by Achieving profound anaesthesia is important for the provision of pain free dentistry. This challenges is considered to be greatest is lower molars (...) with irreversible pulpitis. It has been suggested that the use of premedication with non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (paracetamol) although trials have produced conflicting results. The aim of this review was to assess the efficacy of pre-emptive oral administration of single dose of non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen on the local anaesthetic success in adults with irreversible pulpitis and to find the possible covariates that could predict

2017 The Dental Elf

43. Successful pulpal anesthesia for symptomatic irreversible pulpitis. (Abstract)

Successful pulpal anesthesia for symptomatic irreversible pulpitis. Profound pulpal anesthesia after a successful inferior alveolar nerve block can be difficult to achieve when the clinical condition is a pulpal diagnosis of symptomatic irreversible pulpitis. The authors reviewed the literature as it relates to the anesthesia necessary for endodontic therapy of patients with painful, vital, mandibular teeth diagnosed with symptomatic irreversible pulpitis.Supplemental anesthetic techniques (...) and medications are available that can be used to improve pulpal anesthesia for patients with the clinical condition of symptomatic irreversible pulpitis.The authors identified treatment recommendations for anesthesia in the case of symptomatic irreversible pulpitis based on a review of the available evidence.Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.

2017 Journal of the American Dental Association

44. Anesthetic Efficacy of Articaine and Ketamine for Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis: A Prospective Randomized Double-Blind Study. Full Text available with Trip Pro

Anesthetic Efficacy of Articaine and Ketamine for Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis: A Prospective Randomized Double-Blind Study. The aim of this prospective, randomized, double-blind study was to investigate the effect of articaine combined with ketamine on the success rate of inferior alveolar nerve block (IANB) in posterior mandible teeth with symptomatic irreversible pulpitis.Forty two adult patients with diagnosis of symptomatic irreversible pulpitis (...) pulpitis.

2017 Iranian endodontic journal Controlled trial quality: uncertain

45. [Comparative study of pain releasing effect of two approaches to acute pulpitis in the night emergency]. (Abstract)

[Comparative study of pain releasing effect of two approaches to acute pulpitis in the night emergency]. To compare the clinical effect of 2 methods for acute pulpitis in the night emergency.Two hundred and twenty-three patients with acute pulpitis were randomly divided into experimental group (107 cases) and control group (109 cases). Patients in the experimental group was enclosed formaldehyde cresol (FC) with CAVITON-GC after removal of crown pulp, while patients in the control group

2017 Shanghai kou qiang yi xue = Shanghai journal of stomatology

46. Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis

Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Celebrex (...) Premedication in Teeth With Symptomatic Irreversible Pulpitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03339544 Recruitment Status : Not yet recruiting First Posted : November 13, 2017 Last Update Posted : November 13

2017 Clinical Trials

47. The Effect of Photobiomodulation on the Depth of Anesthesia During Endodontic Treatment of Teeth With Symptomatic Irreversible Pulpitis (Double Blind Randomized Clinical Trial) Full Text available with Trip Pro

The Effect of Photobiomodulation on the Depth of Anesthesia During Endodontic Treatment of Teeth With Symptomatic Irreversible Pulpitis (Double Blind Randomized Clinical Trial) Introduction: Achieving appropriate anesthesia in patients with symptomatic irreversible pulpitis in mandibular molars during endodontic treatment is always one of the most challenging aspects. Photobiomodulation (PBM) has been used in dentistry due to its anti-inflammatory properties and regenerative effects. This study

2017 Journal of lasers in medical sciences Controlled trial quality: uncertain

48. Effect of a Combination of Intranasal Ketorolac and Nitrous Oxide on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. Full Text available with Trip Pro

Effect of a Combination of Intranasal Ketorolac and Nitrous Oxide on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study. Previous studies in patients with irreversible pulpitis have reported increased success of the inferior alveolar nerve block (IANB) using premedication with ketorolac. Preemptive nitrous oxide administration has also shown an increase in the success of the IANB. Recently, ketorolac (...) has been made available for intranasal delivery. Perhaps combining ketorolac and nitrous oxide would increase success. Therefore, the purpose of this prospective, randomized, double-blind study was to determine the effect of a combination of intranasal ketorolac and nitrous oxide/oxygen on the anesthetic success of the IANB in patients presenting with symptomatic irreversible pulpitis.One hundred two patients experiencing spontaneous moderate to severe pain with symptomatic irreversible pulpitis

2017 Journal of Endodontics Controlled trial quality: uncertain

49. Anesthetic Efficacy of Gow-Gates Nerve Block, Inferior Alveolar Nerve Block, and Their Combination in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Randomized Clinical Trial. (Abstract)

Anesthetic Efficacy of Gow-Gates Nerve Block, Inferior Alveolar Nerve Block, and Their Combination in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Randomized Clinical Trial. The purpose of this prospective, randomized clinical trial was to evaluate the anesthetic efficacy of the Gow-Gates nerve block (GGNB), the inferior alveolar nerve block (IANB), and their combination for mandibular molars in patients with symptomatic irreversible pulpitis.One hundred fifty (...) patients diagnosed with symptomatic irreversible pulpitis of a mandibular molar were selected. The patients randomly received 2 GGNB injections, 2 IANB injections, or 1 GGNB injection plus 1 IANB injection of 1.8 mL 2% lidocaine with 1:80,000 epinephrine. Access cavity preparation was initiated 15 minutes after injections. Lip numbness was a requisite for all of the patients. Success was specified as no or mild pain on the basis of Heft-Parker visual analog scale recordings during access cavity

2017 Journal of Endodontics Controlled trial quality: uncertain

50. Up-regulation of TLR2 and TLR4 in high mobility group Box1-stimulated macrophages in pulpitis patients Full Text available with Trip Pro

Up-regulation of TLR2 and TLR4 in high mobility group Box1-stimulated macrophages in pulpitis patients High Mobility Group Box1 (HMGB1) is a nonhistone, DNA-binding protein that serves a crucial role in regulating gene transcription and is involved in a variety of proinflammatory, extracellular activities. The aim of this study was to explore whether HMGB1 stimulation can up-regulate the expression of Toll-like Receptor 2 (TLR2) and Toll-like Receptor 4 (TLR4) on macrophages from pulpitis (...) and to clarify the subsequent events involving Th17 cells and Th17 cell-associated cytokine changes.Having prepared dental pulp tissues of pulpitis and healthy controls, macrophage were isolated and cultured. Macrophages were thereafter stimulated by HMGB1 time course. RT-QPCR, flowcytometer, immunofluorescence, Western blotting, and ELISA techniques were used in the present research.Our results showed that the expression of TLR2 and TLR4 on macrophages stimulated with HMGB1 increased in pulpitis compared

2017 Iranian journal of basic medical sciences

51. Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study Full Text available with Trip Pro

Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study Experiments have previously demonstrated the therapeutic potential of mobilized dental pulp stem cells (MDPSCs) for complete pulp regeneration. The aim of the present pilot clinical study is to assess the safety, potential efficacy, and feasibility of autologous transplantation of MDPSCs in pulpectomized teeth.Five patients with irreversible pulpitis were enrolled and monitored for up to 24 weeks

2017 Stem cell research & therapy

52. Expression and localization of special AT-rich sequence binding protein 2 in murine molar development and the pulp-dentin complex of human healthy teeth and teeth with pulpitis Full Text available with Trip Pro

Expression and localization of special AT-rich sequence binding protein 2 in murine molar development and the pulp-dentin complex of human healthy teeth and teeth with pulpitis Special AT-rich sequence binding protein 2 (SATB2) is a member of the special family of AT-rich binding transcription factors and has a critical role in osteoblast differentiation and craniofacial patterning. However, the expression and distribution of SATB2 in tooth development is largely unknown. The aim of the present (...) study was to detect the expression and distribution of SATB2 during murine molar development and, in human healthy teeth and teeth with pulpitis using immunohistochemistry. Molars were obtained from Kunming mice at embryonic day (E) 13.5, E14.5, E16.5 and E18.5, and postnatal day (P) 1, P5 and P7. In addition, 20 human teeth (10 healthy and 10 teeth with pulpitis) were obtained from young adult patients (age, 24.90±1.65 years) who were scheduled for routine extraction. Immunohistochemical analyses

2017 Experimental and therapeutic medicine

53. Sensitivity, Specificity, Predictive Values, and Accuracy of Three Diagnostic Tests to Predict Inferior Alveolar Nerve Blockade Failure in Symptomatic Irreversible Pulpitis Full Text available with Trip Pro

Sensitivity, Specificity, Predictive Values, and Accuracy of Three Diagnostic Tests to Predict Inferior Alveolar Nerve Blockade Failure in Symptomatic Irreversible Pulpitis The inferior alveolar nerve block (IANB) is the most common anesthetic technique used on mandibular teeth during root canal treatment. Its success in the presence of preoperative inflammation is still controversial. The aim of this study was to evaluate the sensitivity, specificity, predictive values, and accuracy of three (...) diagnostic tests used to predict IANB failure in symptomatic irreversible pulpitis (SIP).A cross-sectional study was carried out on the mandibular molars of 53 patients with SIP. All patients received a single cartridge of mepivacaine 2% with 1 : 100000 epinephrine using the IANB technique. Three diagnostic clinical tests were performed to detect anesthetic failure. Anesthetic failure was defined as a positive painful response to any of the three tests. Sensitivity, specificity, predictive values

2017 Pain research & management

54. Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars.

Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03553407 Recruitment Status : Recruiting First Posted : June 12

2017 Clinical Trials

55. Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis

Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2017 Clinical Trials

56. Three Incomplete Caries Removal Techniques Compared Over Two Years in Primary Molars with Asymptomatic Deep Caries or Reversible Pulpitis. (Abstract)

Three Incomplete Caries Removal Techniques Compared Over Two Years in Primary Molars with Asymptomatic Deep Caries or Reversible Pulpitis. To directly compare the survival rates of three incomplete caries removal techniques that differed in the amount of caries removal and the base material used.Ninety-six primary molars with asymptomatic deep caries or reversible pulpitis were randomly assigned to three groups: (1) indirect pulp treatment (IPT); (2) minimal caries removal with both resin

2017 Pediatric dentistry Controlled trial quality: uncertain

57. Comparative Evaluation of Anesthetic Efficacy of 2% Lidocaine, 4% Articaine, and 0.5% Bupivacaine on Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial. Full Text available with Trip Pro

Comparative Evaluation of Anesthetic Efficacy of 2% Lidocaine, 4% Articaine, and 0.5% Bupivacaine on Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial. To compare the anesthetic efficacy of 1.8 mL of 2% lidocaine with 1:200,000 epinephrine, 4% articaine with 1:100,000 epinephrine, and 0.5% bupivacaine with 1:200,000 epinephrine on producing inferior alveolar nerve block (IANB) in patients with symptomatic

2017 Journal of oral & facial pain and headache Controlled trial quality: uncertain

58. Comparing the anaesthetic efficacy of articaine with lidocaine in patients with irreversible pulpitis: an umbrella review

Comparing the anaesthetic efficacy of articaine with lidocaine in patients with irreversible pulpitis: an umbrella review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

59. Effectiveness of supplemental anesthetic injections in patients with irreversible pulpitis: a systematic review and meta-analysis

Effectiveness of supplemental anesthetic injections in patients with irreversible pulpitis: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record

2019 PROSPERO

60. Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis

Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved (...) Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis (RCT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government

2017 Clinical Trials

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