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Ptosis

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161. Near-identical segregation of mtDNA heteroplasmy in blood, muscle, urinary epithelium, and hair follicles in twins with optic atrophy, ptosis, and intractable epilepsy. Full Text available with Trip Pro

Near-identical segregation of mtDNA heteroplasmy in blood, muscle, urinary epithelium, and hair follicles in twins with optic atrophy, ptosis, and intractable epilepsy. Mitochondrial DNA (mtDNA) disorders have emerged as major causes of inherited neurologic disease. Despite being well recognized for more than 2 decades, the clinical presentation continues to broaden. The phenotypic heterogeneity is partly owing to different percentage levels of mutant mtDNA heteroplasmy in different tissues (...) , but the factors influencing this are poorly understood.This case report describes monozygotic male twins with ptosis, optic atrophy, and recent-onset intractable myoclonic epilepsy. The assessment of respiratory chain enzyme activities in the muscle from 1 twin revealed a severe and isolated defect involving mitochondrial complex I. Mitochondrial DNA sequencing revealed a pathogenic m.14487T>C MTND6 mutation, which was present at very high levels of heteroplasmy in muscle (84%) and lower levels in blood (15

2013 JAMA neurology

162. Ptosis

Ptosis Ptosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Ptosis Ptosis Aka: Ptosis From Related Chapters II. Definition Failed (...) opening III. Causes Congenital Bilateral paralysis of Levator palpebrae superioris Causes complete Ptosis Acquired Disease (Incomplete Ptosis) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Ptosis." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Ptosis (C0033377) Definition (CHV) abnormal lowering of an organ or a part Definition (CHV) abnormal

2015 FP Notebook

163. Pearls & Oy-sters: Maternally inherited diabetes and deafness presenting with ptosis and macular pattern dystrophy Full Text available with Trip Pro

Pearls & Oy-sters: Maternally inherited diabetes and deafness presenting with ptosis and macular pattern dystrophy 22869689 2012 10 15 2018 11 13 1526-632X 79 6 2012 Aug 07 Neurology Neurology Pearls & oy-sters: maternally inherited diabetes and deafness presenting with ptosis and macular pattern dystrophy. e54-6 10.1212/WNL.0b013e31826356ad Ogun Olufunmilola O Departments of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, Canada. Sheldon Claire C Barton Jason J S

2012 Neurology

164. Brow ptosis: are we measuring the right thing? The impact of surgery and the correlation of objective and subjective measures with postoperative improvement in quality-of-life Full Text available with Trip Pro

Brow ptosis: are we measuring the right thing? The impact of surgery and the correlation of objective and subjective measures with postoperative improvement in quality-of-life To assess the effect of brow ptosis on visual function and quality-of-life (QoL), and to determine what measures are associated with post-surgical change in functional status.Prospective longitudinal study. Fifteen consecutive patients undergoing brow-lift surgery from February 2009 to August 2010.pre- and post-operative (...) <0.085). There was a mean 36-point increase in functional index score after brow lift surgery (P<0.001).Self-reported preoperative functional impairment was the only outcome measure significantly (and strongly) associated with post-surgical improvement in functional status (r=-0.833, P<0.001).Surgical repair of brow ptosis results in a measurable increase in health-related QoL. The preoperative QoL score is the best predictor of postoperative improvement in QoL. The best available objective

2012 Eye

165. Cysticercosis and ptosis Full Text available with Trip Pro

Cysticercosis and ptosis 22412281 2012 10 02 2018 11 13 1998-3549 15 1 2012 Jan Annals of Indian Academy of Neurology Ann Indian Acad Neurol Cysticercosis and ptosis. 68 10.4103/0972-2327.93291 Wiwanitkit Somsri S Wiwanitkit House, Bangkhae, Bangkok, Thailand. Wiwanitkit Viroj V eng Journal Article India Ann Indian Acad Neurol 101273955 0972-2327 2012 3 14 6 0 2012 3 14 6 0 2012 3 14 6 1 ppublish 22412281 10.4103/0972-2327.93291 AIAN-15-68b PMC3299080 Orbit. 2008;27(5):370-3 18836935

2012 Annals of Indian Academy of Neurology

166. Surgically Mismanaged Ptosis in a Patient with Congenital Fibrosis of the Extraocular Muscles Type I Full Text available with Trip Pro

Surgically Mismanaged Ptosis in a Patient with Congenital Fibrosis of the Extraocular Muscles Type I Fibrosis syndromes comprise a rare form of severe limitation of ocular motility. An 11-year-old girl was referred for the correction of eyelid retraction. The eyelid retraction occurred immediately following levator resection surgery performed by a plastic surgeon who missed the restrictive extraocular muscle abnormalities. On examination, both eyes were fixed in an infraducted position (20

2012 Middle East African journal of ophthalmology

167. Correction of severe ptosis with a silicone implant suspensor: 22 years of experience. (Abstract)

Correction of severe ptosis with a silicone implant suspensor: 22 years of experience. Patients with severe ptosis caused by poor or absent function of the levator muscle but with good frontalis muscle excursion usually benefit from a frontalis sling procedure. This is currently carried out using organic or inorganic material to connect the upper eyelid to the frontalis muscle.The aim of this study was to evaluate retrospectively 112 patients who underwent frontalis sling procedures between

2012 Plastic and reconstructive surgery

168. Safety, efficacy, and modifications of the dermal bra technique for reduction mammaplasty and ptosis correction: a 10-year retrospective study. (Abstract)

Safety, efficacy, and modifications of the dermal bra technique for reduction mammaplasty and ptosis correction: a 10-year retrospective study. The dermal bra technique was reported by the authors in 2003 for reduction mammaplasty and ptosis correction. The authors have summarized and modified continuously and here share their experience and analyze the long-term safety and efficacy of this technique.Three hundred forty-seven patients underwent the dermal bra technique in the authors (...) of the nipple-areola complex. Long-term complications were found in 28 breasts (6.6 percent), including widened scar and enlarged areola, irregular areola, secondary ptosis, sunken nipple-areola complex, numbness of the nipple-areola complex, cyst, and chronic infection. Except for one case of nipple-areola complex numbness, all complications were corrected successfully. The long-term satisfaction rate was 95.7 percent. With three major modifications (W- or V-shaped gland resection, medial rotation of gland

2012 Plastic and reconstructive surgery

169. Correcting upper eyelid retraction by means of pretarsal levator lengthening for complications following ptosis surgery. (Abstract)

Correcting upper eyelid retraction by means of pretarsal levator lengthening for complications following ptosis surgery. Eyelid retraction is a condition in which the upper eyelid ascends past its ideal position, 1 to 2 mm below the upper limbus of the cornea. This condition can be a result of overcorrecting ptosis, hyperthyroidism, and other causes. The authors present studies conducted on eyelid retraction caused by ptosis overcorrection. An innovative approach for levator lengthening using (...) the pretarsal tissue as a spacer flap is introduced as a method to correct the retraction.A series of 60 patients over a 6-year period underwent 71 eyelid procedures to correct upper lid retraction following upper blepharoplasty and ptosis repair. All eyelid retractions ranged from 1 to 3 mm above its ideal position. All eyelids were corrected with the authors' technique of lengthening the levator with pretarsal tissue. Twelve cases that required further lengthening were completed by creating a superiorly

2012 Plastic and reconstructive surgery

170. Pubic contouring after massive weight loss in men and women: correction of hidden penis, mons ptosis, and labia majora enlargement. (Abstract)

Pubic contouring after massive weight loss in men and women: correction of hidden penis, mons ptosis, and labia majora enlargement. Weight gain and subsequent weight loss usually result in unsightly large fat deposition in the pubic areas along with ptosis of the fat pad and skin. Men also complain of burying of the penis and the woman complains of labia majora enlargement, both causing secondary sexual dysfunction, hygiene issues, discomfort, and aesthetic concerns. Even with weight loss, most

2012 Plastic and reconstructive surgery

171. Outcomes of mild to moderate upper eyelid ptosis correction using Müller's muscle-conjunctival resection. Full Text available with Trip Pro

Outcomes of mild to moderate upper eyelid ptosis correction using Müller's muscle-conjunctival resection. Müller's muscle-conjunctival resection is used to correct mild to moderate ptosis commonly encountered in the rejuvenation patient population. The authors examined its efficacy and analyzed variables that potentially affect outcomes.Patients who underwent ptosis correction using Müller's muscle-conjunctival resection with greater than 10-month follow-up were included. Amount of ptosis (...) reduction, eyelid symmetry, effects of concomitant facial aesthetic operations, and adverse outcomes were analyzed. Patients were grouped into medium- (<24 months after surgery) and long-term follow-up (>24 months) cohorts to determine whether outcomes changed over time.Forty patients with a mean follow-up of 28 months combined for a total of 70 resection operations. Resection significantly reduced ptosis by a mean of 1.48 ± 0.88 mm (p < 0.001), corresponding to 0.19 mm of eyelid elevation for every 1.0

2012 Plastic and reconstructive surgery

172. A Case of Cephalic Tetanus with Unilateral Ptosis and Facial Palsy Full Text available with Trip Pro

A Case of Cephalic Tetanus with Unilateral Ptosis and Facial Palsy Cephalic tetanus is defined as a combination of trismus and paralysis of one or more cranial nerves. Cranial nerves III, IV, VI, VII, and XII may be affected, but the facial nerve is most frequently implicated. A 64-year-old female visited hospital for left ptosis followed by facial palsy after a left forehead abrasion in a car accident. At nine days post injury, left ptosis developed, left facial palsy developed twelve days (...) post injury, and at fifteen days post injury, trismus and dysphagia developed. The following day, there was progression of symptoms to generalized tetanus, such as dyspnea and generalized rigidity. Videofluoroscopic swallow study showed penetration and aspiration. We report a case of cephalic tetanus with ptosis, facial palsy, and dysphagia, which progressed to generalized tetanus.

2012 Annals of rehabilitation medicine

173. Exposure keratopathy following silicone frontalis suspension in adult neuro- and myogenic ptosis. (Abstract)

Exposure keratopathy following silicone frontalis suspension in adult neuro- and myogenic ptosis. To evaluate the incidence of exposure keratopathy following silicone frontalis suspension in adult neuro- and myogenic blepharoptosis.Retrospective noncomparative analysis of the charts of 69 cases (101 eyelids) of silicone frontalis suspension.Sixty-one patients (93 eyelids) had myogenic ptosis, and eight patients (eight eyelids) had neurogenic ptosis. Preoperative diagnoses included chronic (...) ) and congenital ptosis (33% of eyes). Patients with oculopharyngeal dystrophy did not develop PEE. Corneal ulceration developed in three eyes (two patients): one eye was successfully treated with local antibiotic ointments and lubricants, a bilateral corneal ulceration in the second patient was successfully treated with partial conjunctival grafts.This study cohort demonstrated a 26% risk of exposure keratopathy following silicone frontalis suspension. The risk of major corneal complications

2012 Acta ophthalmologica

174. Brow Ptosis after Temporal Artery Biopsy: Incidence and Associations. (Abstract)

Brow Ptosis after Temporal Artery Biopsy: Incidence and Associations. Temporal artery biopsy (TAB), performed for the diagnosis of giant cell arteritis, has a low reported rate of complications. One complication is damage to the facial nerve branches, which can result in brow ptosis and/or orbicularis oculi weakness. However, the incidence of facial nerve damage after TAB is unknown.Prospective, institutional review board-approved study of all TABs performed by 2 surgeons over a 17-month

2012 Ophthalmology

175. Deficiency for the Ubiquitin Ligase UBE3B in a Blepharophimosis-Ptosis-Intellectual Disability Syndrome. Full Text available with Trip Pro

Deficiency for the Ubiquitin Ligase UBE3B in a Blepharophimosis-Ptosis-Intellectual Disability Syndrome. Ubiquitination plays a crucial role in neurodevelopment as exemplified by Angelman syndrome, which is caused by genetic alterations of the ubiquitin ligase-encoding UBE3A gene. Although the function of UBE3A has been widely studied, little is known about its paralog UBE3B. By using exome and capillary sequencing, we here identify biallelic UBE3B mutations in four patients from three (...) unrelated families presenting an autosomal-recessive blepharophimosis-ptosis-intellectual-disability syndrome characterized by developmental delay, growth retardation with a small head circumference, facial dysmorphisms, and low cholesterol levels. UBE3B encodes an uncharacterized E3 ubiquitin ligase. The identified UBE3B variants include one frameshift and two splice-site mutations as well as a missense substitution affecting the highly conserved HECT domain. Disruption of mouse Ube3b leads to reduced

2012 American Journal of Human Genetics

176. The combination of polyalanine expansion mutation and a novel missense substitution in transcription factor FOXL2 leads to different ovarian phenotypes in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) patients. Full Text available with Trip Pro

The combination of polyalanine expansion mutation and a novel missense substitution in transcription factor FOXL2 leads to different ovarian phenotypes in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) patients. What are the implications of multiple alterations of the forkhead box L2 (FOXL2) gene in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) patients?A multi-mutation of FOXL2, consisting of the expansion of the polyalanine tract from 14 to 24 residues (FOXL2-Ala24

2012 Human Reproduction

177. A New Method of Medial Epicanthoplasty for Patients with Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome. (Abstract)

A New Method of Medial Epicanthoplasty for Patients with Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome. To describe a medial epicanthoplasty technique using the skin redraping method and review the surgical outcome in patients with blepharophimosis-ptosis-epicanthus inversus syndrome (BPES).Retrospective, noncomparative, interventional case series with the description of a new surgical technique.Sixteen consecutive Asian patients with BPES.The charts of patients with BPES who underwent

2012 Ophthalmology

178. Autologous inferior dermal sling (autoderm) with concomitant skin-envelope reduction mastectomy: an excellent surgical choice for women with macromastia and clinically significant ptosis. (Abstract)

Autologous inferior dermal sling (autoderm) with concomitant skin-envelope reduction mastectomy: an excellent surgical choice for women with macromastia and clinically significant ptosis. Skin-sparing mastectomy and prosthetic reconstruction can be complicated by poor surgical outcomes in large-breasted, obese women. This article describes a single surgeon's experience comparing conventional skin-sparing mastectomy (SSM) and skin-reduction mastectomy using an autologous vascularized inferior (...) dermal/cutaneous sling (autoderm).From July 2007 to May 2012, patients undergoing skin-sparing mastectomy were evaluated for surgical outcomes. After July 2009, the surgeon performed skin-reduction mastectomies with autoderm (SRM-AD) on all patients with macromastia or grade 3-4 ptosis. Remaining patients in this time period (SSM-cont) underwent conventional skin-sparing mastectomies while all previous patients (historical) also underwent skin-sparing mastectomies (SSM-hist). A predictive model

2012 Annals of Surgical Oncology

179. Primary bilateral silicone frontalis suspension for good levator function ptosis in oculopharyngeal muscular dystrophy. (Abstract)

Primary bilateral silicone frontalis suspension for good levator function ptosis in oculopharyngeal muscular dystrophy. To evaluate outcomes of patients with oculopharyngeal muscular dystrophy (OPMD) with levator function (LF) ≥ 10mm who underwent primary bilateral silicone frontalis suspension.31 patients with OPMD satisfied the following inclusion criteria: LF ≥ 10 mm; no previous eyelid surgery; and pre-operative measurements, silcone frontalis suspension and post-operative measurements (...) ptosis after their initial surgery.Primary bilateral silicone frontalis suspension for good LF ptosis secondary to OPMD appears to be an effective, safe treatment which gives symmetrical upper lid elevation. Early sling adjustment may be required to attain optimal eyelid height and late tightening for expectant loosening of the sling is safe and effective.

2012 British Journal of Ophthalmology

180. Preoperative and Intraoperative Factors Related to the Development of Ptosis After Retinal Surgery

Preoperative and Intraoperative Factors Related to the Development of Ptosis After Retinal Surgery Preoperative and Intraoperative Factors Related to the Development of Ptosis After Retinal Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Preoperative and Intraoperative Factors Related to the Development of Ptosis After Retinal Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01752478 Recruitment Status : Completed First Posted : December 19, 2012 Last Update Posted : May 20, 2016

2012 Clinical Trials

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