How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,093 results for

Prophylactic Oophorectomy

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Relationship satisfaction predicts sexual activity following risk-reducing salpingo-oophorectomy (Full text)

Relationship satisfaction predicts sexual activity following risk-reducing salpingo-oophorectomy Changes in sexual function are a common outcome following risk-reducing salpingo-oophorectomy (RRSO), a prophylactic surgery for women at high risk of ovarian and other gynecologic cancers. Despite the known importance of sexuality in patients' quality of life and satisfaction with surgery, little is known about what predicts sexual activity following RRSO. The present study examined how mental

2014 Journal of psychosomatic obstetrics and gynaecology PubMed abstract

42. Effect of hormone therapy on quality of life and risk of breast cancer on carriers of BRCA mutation who underwent bilateral prophylactic salpingo-oophorectomy

Effect of hormone therapy on quality of life and risk of breast cancer on carriers of BRCA mutation who underwent bilateral prophylactic salpingo-oophorectomy Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2014 PROSPERO

43. Prophylactic oophorectomy with colorectal cancer resection: a systematic review and meta-analysis

Prophylactic oophorectomy with colorectal cancer resection: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address

2014 PROSPERO

44. A cost-effectiveness analysis of prophylactic surgery versus gynecologic surveillance for women from hereditary non-polyposis colorectal cancer (HNPCC) families

syndrome or hereditary non-polyposis colorectal cancer. Interventions The interventions were annual gynaecologic examinations, over a lifetime; annual surveillance, including transvaginal ultrasound, endometrial biopsy, and blood serum CA-125 testing; and prophylactic hysterectomy and bilateral salpingo-oophorectomy at age 30 years. Location/setting USA/in-patient secondary care. Methods Analytical approach: A decision tree combined published literature to compare the costs and outcomes of the three (...) health states were from published studies. Measure of benefit: The measure of benefit was quality-adjusted life-years (QALYs). Future benefits were discounted at an annual rate of 3%. Cost data: The direct costs were those of gynaecological examinations; screening tests; prophylactic abdominal hysterectomy and salpingo-oophorectomy; chemotherapy; radiation for endometrial cancer; pathology evaluations; and cancer care. The costs of cancer care were from a study published in 1987, using 1984 prices

2012 NHS Economic Evaluation Database.

45. Comparing surgical outcome and ovarian reserve after laparoscopic hysterectomy between two methods of with and without prophylactic bilateral salpingectomy: A randomized controlled trial. (Full text)

Comparing surgical outcome and ovarian reserve after laparoscopic hysterectomy between two methods of with and without prophylactic bilateral salpingectomy: A randomized controlled trial. This study aimed to compare the surgical outcome and ovarian reserve in premenopausal women undergoing laparoscopic hysterectomy (without oophorectomy) for benign cause between two methods of with and without prophylactic bilateral salpingectomy.In a prospective randomized clinical trial, 62 premenopausal (...) , in both groups, postoperative AMH levels were significantly lower and FSH levels were significantly higher than before surgery.Prophylactic bilateral salpingectomy at the time of laparoscopic hysterectomy neither has a negative effect on ovarian reserve nor increases the surgical risk. Therefore, we may recommend gynecologic surgeons to perform prophylactic bilateral salpingectomy during laparoscopic hysterectomy to conserve both ovaries.

2018 Journal of cancer research and therapeutics Controlled trial quality: uncertain PubMed abstract

46. Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation carriers and controls. (Abstract)

Tubal epithelial lesions in salpingo-oophorectomy specimens of BRCA-mutation carriers and controls. A precursor lesion for ovarian carcinoma, tubal intraepithelial carcinoma (TIC), has been identified in BRCA-mutation carriers undergoing prophylactic bilateral salpingo-oophorectomy (pBSO). Other lesions were also identified in fallopian tubes, but different terminology, interpretation, and lack of knowledge of normal epithelium, have hampered to unravel their possible role in carcinogenesis (...) . The aim of this study is to classify tubal epithelial lesions in BRCA-mutation carriers and controls to enable comparison of prevalence, area of localization, and possible malignant potential.Two hundred twenty-six BRCA1/2-mutation carriers were included; ovaries and fallopian tubes, embedded completely, were reviewed. Controls included 105 women who underwent BSO for non-malignant reasons. Tubal epithelial lesions included the following categories: hyperplasia, minor epithelial atypia, TIC

2012 Gynecologic Oncology

47. Early (“Prophylactic”) Oophorectomy and Adrenalectomy in Carcinoma of the Breast: A Ten-Year Follow-Up (Full text)

Early (“Prophylactic”) Oophorectomy and Adrenalectomy in Carcinoma of the Breast: A Ten-Year Follow-Up Early "prophylactic" oophorectomy and adrenalectomy has been performed on 12 patients with carcinoma of the breast. The patients selected were considered to have a very bad prognosis on account of axillary node involvement associated with internal mammary chain deposits (9 patients), supraclavicular nodes (2 patients) and a parasternal mass (1 patient). Five patients had evidence of spread (...) to malignancy determined histologically, but did have an association with the extent of invasion of the axillary nodes. Urinary oestrogen estimations performed in 4 patients did not give any evidence that outcome was related to persistence of oestrogen production. Details of the patients' management and replacement therapy are given and from prolonged personal follow-up of these patients it is concluded that women who have undergone oophorectomy and adrenalectomy are able to lead full and active lives.

1970 British journal of cancer PubMed abstract

48. Long-term risks of prophylactic oophorectomy compared to ovary preservation at the time of hysterectomy for benign indications

Long-term risks of prophylactic oophorectomy compared to ovary preservation at the time of hysterectomy for benign indications Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2013 PROSPERO

49. Differences Among a Modern Cohort of BRCA Mutation Carriers Choosing Bilateral Prophylactic Mastectomies Compared to Breast Surveillance. (Full text)

Differences Among a Modern Cohort of BRCA Mutation Carriers Choosing Bilateral Prophylactic Mastectomies Compared to Breast Surveillance. Women with a BRCA mutation have significantly elevated breast cancer risk, which can be reduced by >90% with bilateral prophylactic mastectomy (BPM). We sought to compare a cohort of BRCA mutation carriers choosing BPM versus breast surveillance to better elucidate factors that may impact decision making.Women with a BRCA mutation were retrospectively (...) cancer (10 vs. 20%, p = 0.01). Furthermore, women undergoing BPM were more likely to be married (78 vs. 62%, p = 0.01), to have more children (median 2 vs. 1, p < 0.001), and to have undergone a prophylactic oophorectomy (61 vs. 37%, p < 0.001). Women choosing BPM had more first-degree relatives (63 vs. 48%, p = 0.01) or a sister (23 vs. 14%, p = 0.02) with a history of breast cancer and were more likely to have a family member with ovarian cancer under the age of 40 years (9 vs. 4%, p = 0.03

2017 Annals of Surgical Oncology PubMed abstract

50. Feasibility of Prophylactic Salpingectomy During Vaginal Hysterectomy. (Full text)

Feasibility of Prophylactic Salpingectomy During Vaginal Hysterectomy. The American Congress of Obstetricians and Gynecologists recommends that "the surgeon and patient discuss the potential benefits of the removal of the fallopian tubes during a hysterectomy in women at population risk of ovarian cancer who are not having an oophorectomy," resulting in an increasing rate of salpingectomy at the time of hysterectomy. Rates of salpingectomy are highest for laparoscopic and lowest for vaginal (...) hysterectomy.The primary objective of this study was to determine the feasibility of bilateral salpingectomy at the time of vaginal hysterectomy. Secondary objectives included identification of factors associated with unsuccessful salpingectomy and assessment of its impact on operating time, blood loss, surgical complications, and menopausal symptoms.This was a multicenter, prospective study of patients undergoing planned vaginal hysterectomy with bilateral salpingectomy. Baseline medical data along

2017 American Journal of Obstetrics and Gynecology PubMed abstract

51. Prophylactic Surgery: For Whom, When and How? (Full text)

Prophylactic Surgery: For Whom, When and How? Risk-reducing surgery has proved to be a reasonable procedure in healthy women with a definitely elevated risk of developing cancer. Here we consider the elevated risk of breast and ovarian cancer. There is a clear indication for such surgery in healthy women with a pathogenic BRCA1/2 mutation. For these patients, a risk-reducing bilateral mastectomy leads to a verifiable reduction in mortality from breast cancer, particularly for young patients (...) and a better prognosis of the primary disease make a contralateral mastectomy (CPM) more reasonable. In the case of BRCA mutation-related cancer, a reduction of mortality through CPM has been proven. A risk-reducing adnexectomy is basically recommended for BRCA mutation carriers. Healthy premenopausal women need a subsequent hormone replacement therapy. The prognosis of the patients is dominated by the ovarian carcinoma. This can be prevented by risk-reducing salpingo-oophorectomy in 95% of the cases.

2017 Breast Care PubMed abstract

52. Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer. (Abstract)

Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer. In the era of advanced cancer genomics, our recognition of hereditary cancer mutations continues to increase. Two of these conditions, which carry an increased risk of female cancers including endometrial, ovarian, breast, are hereditary breast and ovarian cancer syndrome and Lynch syndrome. Risk-reducing surgery, such as mastectomy, salpingo-oophorectomy, and hysterectomy may

2019 Journal of Surgical Oncology

53. Effect of prophylactic dexamethasone on nausea and vomiting after laparoscopic gynecological operation: meta-analysis

Effect of prophylactic dexamethasone on nausea and vomiting after laparoscopic gynecological operation: meta-analysis Effect of prophylactic dexamethasone on nausea and vomiting after laparoscopic gynecological operation: meta-analysis Effect of prophylactic dexamethasone on nausea and vomiting after laparoscopic gynecological operation: meta-analysis Wang B, He KH, Jiang MB, Liu C, Min S CRD summary This review found that prophylactic administration of dexamethasone was associated with less (...) postoperative nausea and vomiting in patients who underwent laparoscopic gynaecological surgery. Potential for some biases and a lack of information on study quality make the reliability of the authors' conclusions unclear. Authors' objectives To evaluate the effect of prophylactic administration of dexamethasone on post-surgical nausea and vomiting in patients who underwent laparoscopic gynaecological surgery. Searching PubMed, EMBASE, Web of Science and Cochrane Central Register of Controlled Trials

2011 DARE.

54. Evidence-based medicine: an analysis of prophylactic bilateral oophorectomy at time of hysterectomy for benign conditions (Full text)

Evidence-based medicine: an analysis of prophylactic bilateral oophorectomy at time of hysterectomy for benign conditions 21331276 2011 07 14 2018 11 13 1718-7729 18 1 2011 Jan Current oncology (Toronto, Ont.) Curr Oncol Evidence-based medicine: an analysis of prophylactic bilateral oophorectomy at time of hysterectomy for benign conditions. 13-5 Larson C A CA University of Kentucky, Lexington, KY, U.S.A. eng Journal Article Canada Curr Oncol 9502503 1198-0052 Prophylactic bilateral (...) oophorectomy hysterectomy incidental bilateral oophorectomy noncancerous uterine fibroids 2011 2 19 6 0 2011 2 19 6 0 2011 2 19 6 1 ppublish 21331276 PMC3031351 J Med Ethics. 2002 Feb;28(1):10-6 11834752 Calif Med. 1958 Jul;89(1):30-2 13561114 Obstet Gynecol. 2005 Aug;106(2):219-26 16055568 Lancet Oncol. 2006 Oct;7(10):821-8 17012044 Neurology. 2008 Jan 15;70(3):200-9 17761549 BMJ. 1996 Jan 13;312(7023):71-2 8555924 Neurodegener Dis. 2008;5(3-4):257-60 18322406 Menopause Int. 2008 Sep;14(3):111-6 18714076

2011 Current Oncology PubMed abstract

55. Quality of life and health status after prophylactic salpingo-oophorectomy in women who carry a BRCA mutation: A review. (Abstract)

Quality of life and health status after prophylactic salpingo-oophorectomy in women who carry a BRCA mutation: A review. Prophylactic salpingo-oophorectomy is recommended to women who carry a BRCA1 or BRCA2 mutation at age 35 or after childbearing is complete. This procedure is the mainstay of ovarian and fallopian tube cancer prevention in these women. Therefore an understanding of the short and long-term impact of the surgery is essential. Salpingo-oophorectomy, particularly when done prior (...) and after surgery, however vasomotor symptoms related to surgical menopause and changes in sexual functioning are common. HRT appears to mitigate some but not all of these symptoms. Women report high levels of satisfaction with their decision to have the surgery despite the impact of prophylactic salpingo-oophorectomy. Studies of the long term health and quality of life after salpingo-oophorectomy in women who carry a BRCA mutation have not yet been published.Copyright © 2011 Elsevier Ireland Ltd. All

2011 Maturitas

56. The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation. (Abstract)

The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation. Prophylactic salpingo-oophorectomy is recommended to women who carry a BRCA1 or BRCA2 mutation to reduce the risks of breast, ovarian and fallopian tube cancer. We measured the impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual functioning in women with a BRCA mutation.Women who underwent prophylactic salpingo-oophorectomy between October 1 (...) , 2002 and June 26, 2008 for a known BRCA1 or BRCA2 mutation were invited to participate. Participants completed questionnaires before prophylactic surgery and again one year after surgery. Measures of sexual functioning and menopausal symptoms before and after surgery were compared. Satisfaction with the decision to undergo prophylactic salpingo-oophorectomy was evaluated.114 women who underwent prophylactic surgery completed questionnaires before and one year after surgery. Subjects who were

2011 Gynecologic Oncology

57. Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis

, hysterectomy, removal of the uterus, bilateral oophorectomy, removal of both ovaries) at least 6 months before dosing) or one year post menopausal), abstinent or using adequate contraceptive precautions (eg, intrauterine contraceptive device; oral contraceptives; diaphragm, cervical cap, or condom in combination with contraceptive jelly, cream or foam; Norplant® or Depo-Provera®) from 3 months prior to this study through 56 days after challenge A negative pregnancy test at the time of enrollment Free (...) Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2017 Clinical Trials

58. Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women

than 2 x upper limit of normal (ULN) and total bilirubin (Tbili) less than or equal to 2.5 x ULN HCV antibody negative If of reproductive potential (defined as pre-menopausal women who have not had a sterilization procedure per self-report, such as hysterectomy, bilateral oophorectomy, tubal ligation or salpingectomy), must have a negative beta human chorionic gonadotropin (βHCG) pregnancy test (sensitivity of less than or equal to 25 mIU/mL) performed (and results known) on the same day (...) Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record

2017 Clinical Trials

59. A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI

status: Women who are pregnant or planning a pregnancy within 1 month of the end of study; Women who are breastfeeding; Women of childbearing potential who are unwilling or unable to use two highly effective methods of birth control to avoid pregnancy for the entire study period, as evaluated by the Investigator. Women who are not of childbearing potential are those that have a history of hysterectomy, bilateral oophorectomy, or are postmenopausal with no history of menstrual flow for ≥ 12 months (...) A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer

2016 Clinical Trials

60. Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review. (Abstract)

prophylactic surgery vs observation with respect to breast and ovarian cancer risk reduction and mortality in BRCA mutation carriers.Bilateral risk-reducing mastectomy provides a 90% to 95% risk reduction in BRCA mutation carriers, although the data do not demonstrate improved mortality. The reduction in ovarian and breast cancer risks using risk-reducing bilateral salpingo-oophorectomy has translated to improvement in survival.Clinical management of patients at increased risk for breast cancer requires (...) Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review. Mutations in BRCA1 or BRCA2 genes results in an elevated risk for developing both breast and ovarian cancers over the lifetime of affected carriers. General surgeons may be faced with questions about surgical risk reduction and survival benefit of prophylactic surgery.A systematic literature review was performed using the electronic databases PubMed, OVID MEDLINE, and Scopus comparing

2016 American journal of surgery

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>