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Promethazine

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101. How can nausea and vomiting be treated during pregnancy?

How can nausea and vomiting be treated during pregnancy? How can nausea and vomiting be treated during pregnancy? – SPS - Specialist Pharmacy Service – The first stop for professional medicines advice Menu · · 27th November 2019 · UKMi This Medicines Q&A evaluates the published information available on the safety of the treatment options for nausea and vomiting in pregnancy. It includes information on the efficacy and safety of antihistamines (promethazine, cyclizine, prochlorperazine

2019 Specialist Pharmacy Services

104. Analgesia and Anesthesia for the Breastfeeding Mother

. Of the anticholinergic agents, atropine is found in trace amountsinbreastmilk.Glycopyrrolateisnotexpected tobefoundinbreastmilkandispoorlyabsorbedthrough the gastrointestinal tract. 5 Antiemetics are used commonly in the perioperative period, and most of these medications are considered safe during breastfeeding. Ondansetron, dexamethasone, and metoclopramide may be preferred because of their lack of sedating side effects. 3 (IV) Prochlorperazine, promethazine, and scopolamine are likely safe, but may lead (...) to maternal sedation; promethazine and scopol- amine may also adversely affect milk supply if given repeatedly. 30–32 (III) Analgesics Opioid analgesics. Opioids are frequently used during surgery as part of a balanced anesthetic technique, and they may be continued postoperatively for pain. All opioids transferintobreastmilkinvaryingamounts,anddifferences in breast milk concentration along with variation in oral availability make certaintypes ofthesemedications moreor less safe for a breastfeeding mother

2017 Academy of Breastfeeding Medicine

105. CRACKCast E099 – Urological Disorders

; prepubescent—supportive only [6] What are the causes of different urine colour pigmentation? Straight from Life in the fast lane Green Drugs: Cimetidine, Promethazine, Amitriptyline, Flutamide, Indomethacin, Methocarbamol, Methylene blue, Mitoxantrone, Propofol, Phenylbutazone, Triamterene Condition: Hartnup Disease, Indicanemia, Indicanuria Infection: Pseudomonas Infection Dyes: Carbolic Acid, Flavine derivatives, Indigo Blue, Methylene Blue, Resorcinol Other: Clorets, Listerine, Magnesium Salicylate

2017 CandiEM

106. Delirium in Adult Cancer Patients: ESMO Clinical Practice Guidelines

anticholinergic activity, e.g. tricyclic antidepressants, diphenhydramine, promethazine, trihexyphenidyl, hyoscine butylbromide Other psychoactive: antipsychotics, antidepressants, levodopa, lithium Anti-infectives: cipro?oxacin, acyclovir, ganciclovir Histamine H2 blockers Omeprazole Immunomodulators: interferon, interleukins, ciclosporin Medication polypharmacy Otherstatusorpredisposingcomorbidities[5,39] Age> 70 years Pre-existing cognitive impairment, e.g. dementia History of delirium Hearing impairment

2018 European Society for Medical Oncology

107. Joint BAP NAPICU evidence-based consensus guidelines for the clinical management of acute disturbance: De-escalation and rapid tranquillisation

hospital and forensic psychiatry. We conclude that the variety of options available for the management of acute disturbance goes beyond the standard choices of lorazepam, haloperidol and promethazine and includes 1 Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College, London, UK 2 Maudsley Hospital, South London and Maudsley NHS Foundation Trust, London, UK 3 The Centre for Psychiatry, Imperial College London, London, UK 4 Wotton Lawn Hospital, together (...) Intramuscular antipsychotics in combination with other medications 18 Intravenous 18 Adverse effects 19 From evidence to practice 19 Other interventions 19 Promethazine 19 Loxapine 20 Levomepromazine 20 Zuclopenthixol acetate 21 Dexmedetomidine 22 Barbiturates 22 Valproate 22 Ketamine 22 Electroconvulsive therapy 23 From evidence to practice 24 Modifiers, special settings and circumstances 24 Pregnancy 24 Intoxication and withdrawal 25 Rapid tranquillisation in the general hospital 26 Psychiatric intensive

2018 British Association for Psychopharmacology

108. Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold

drank” is acocktail used by teens or young adults in which promethazine with codeine syrup is combined with soda, fruit candy, or even alcohol. This mixture produces a sensation of relaxation, euphoria, and intoxication. 40 These medication misadventures can lead to serious complications and even death. 4. In pediatric patients (aged < 18 years) with cough due to the common cold, we suggest avoiding use of codeine-containing medications because of the potential for serious side effects including

2017 American College of Chest Physicians

110. CRACKCast E029 – Nausea and Vomiting

Prochlorperazine, haloperidol, promethazine s/e: dystonic reactions (4%), sedation, restlessness (16%) Treated: with diphenhydramine or benztropine Metoclopramide (prokinetic agent – increased gastric emptying) Has mild anticholinergic and antiserotonin effects Useful in GERD, gastroparesis s/e: tardive dyskinesia, drowsiness, diarrhea, Serotonin antagonists Ondansetron – s/e headaches and constipation/diarrhea Benzodiazepines: No literature to support their routine use for non-specific N/V in the ED Non-pharm

2017 CandiEM

112. Adhesion prevention agents for gynaecological surgery: an overview of Cochrane reviews. Full Text available with Trip Pro

) and pharmacological agents (gonadotrophin-releasing hormone agonist, reteplase plasminogen activator, N,O-carboxymethyl chitosan, steroid agents, intraperitoneal noxytioline, intraperitoneal heparin, systemic promethazine) with control or each other. Both reviews met all of the criteria of the AMSTAR assessment.The reviews included as outcomes both the primary outcomes of this overview (pelvic pain, pregnancy, live birth rate and quality of life (QoL)) and our secondary outcomes (adverse effects, presence

2015 Cochrane

113. Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children

Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01118884 Recruitment Status : Unknown Verified April 2010 by Shahid Beheshti University. Recruitment status

2010 Clinical Trials

114. Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department

Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01129934 Recruitment Status : Unknown Verified May 2010 by Tel

2010 Clinical Trials

115. Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting

Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy (...) of Low Dose Promethazine for Postoperative Nausea and Vomiting The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01159548 Recruitment Status : Terminated (Population of interest was no longer available) First Posted : July 9, 2010 Last Update Posted : July 27, 2011 Sponsor: Women's College Hospital

2010 Clinical Trials

116. Development and validation of a sensitive LC-MS method for the determination of promethazine hydrochloride in human plasma and urine. (Abstract)

Development and validation of a sensitive LC-MS method for the determination of promethazine hydrochloride in human plasma and urine. We developed and validated a sensitive and low sample volume liquid chromatographic-mass spectrometric (LC-MS) method for determination of Promethazine hydrochloride in human plasma (0.5 ml) or urine (0.1 ml). The lower limit of quantification in human plasma and urine was 1.00 ng/ml. The inter- and intra-day precisions (CV %) in both plasma and urine were lower (...) than 10%, the mean method accuracies and recoveries from spiked plasma samples at three concentrations were more than 97%. The developed method was successfully applied to determine Promethazine hydrochloride in human plasma and urine, and proved suitable to clinical pharmacokinetic study.

2010 European journal of drug metabolism and pharmacokinetics Controlled trial quality: uncertain

117. Pharmacokinetics, safety and tolerance of single- and multiple-dose of a novel compound tramadol hydrochloride injection (35 mg tramadol hydrochloride, 45 mgl promethazine hydrochloride) in Chinese healthy subjects. (Abstract)

Pharmacokinetics, safety and tolerance of single- and multiple-dose of a novel compound tramadol hydrochloride injection (35 mg tramadol hydrochloride, 45 mgl promethazine hydrochloride) in Chinese healthy subjects. The pharmacokinetics of Tramadol and Promethazine after a single dose of 40, 80 and 120 mg intramuscular injecting CTHI was evaluated in healthy volunteers. Physical exam, vital signs, clinical laboratory tests and electrocardiogram measurements were monitored to assess the safety (...) and tolerance of the drug. The plasma levels of Tramadol and Promethazine in serial samples were measured by a validated HPLC-MS method. No subject showed any drug-related clinically significant changes on physical examination, vital signs or laboratory tests.

2010 European journal of drug metabolism and pharmacokinetics Controlled trial quality: uncertain

118. Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. Full Text available with Trip Pro

Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum.Women at their first hospitalization for hyperemesis gravidarum were approached when intravenous antiemetic therapy was needed. They were randomly assigned to receive 25 mg promethazine or 10 mg metoclopramide every 8 hours for 24 hours in a double-blind study. Primary outcomes were vomiting episodes (...) by diary and well-being visual numerical rating scale score (10-point scale) in the 24-hour main study period. Participants also filled out an adverse-effects questionnaire at 24 hours and a nausea visual numerical rating scale score at recruitment and at 8, 16, and 24 hours.A total of 73 and 76 women, randomized to metoclopramide and promethazine, respectively, were analyzed. Median vomiting episodes were one (range 0-26) compared with two (range 0-26) (P=.81), and well-being visual numerical rating

2010 Obstetrics and Gynecology Controlled trial quality: predicted high

120. Constipation in older adults: Stepwise approach to keep things moving

) Anticholinergic drugs: antipsychotic drugs, benztropine, oxybutynin Anti-Parkinson drugs: amantadine, bromocriptine, pramipexole Anticonvulsant drugs: gabapentin, phenytoin, pregabalin Antidepressant drugs: tricyclic antidepressants, paroxetine Antidiarrheal drugs: diphenoxylate, loperamide Antiemetic drugs: dimenhydrinate, ondansetron, prochlorperazine, promethazine, scopolamine Antihistamine drugs: diphenhydramine, hydroxyzine Antihypertensive drugs: α-adrenergic agonists (eg, clonidine), β-blockers

2016 RxFiles

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