How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,046 results for


Latest & greatest

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

102. Perioperative Beta Blockade in Noncardiac Surgery: A Systematic Review for the 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery

specific drug use (digoxin, quinidine, procainamide, amiodarone, diltiazem, verapamil) Intrathoracic (100%) procedures 0% 62% males, mean age 62.5 y, 6% with prior MI, 5% with current angina DECREASE-I (1999) 10588963 112 Pts with ≥1 cardiac risk factor (>70 y of age, angina; prior MI, HF, diabetes mellitus, limited exercise capacity, ventricular arrhythmias) and positive result on dobutamine stress echocardiography. Prior beta-blocker use, asthma, very high-risk dobutamine stress echocardiography

Full Text available with Trip Pro

2014 American Heart Association

105. Perioperative Beta Blockade in Noncardiac Surgery: A Systematic Review for the 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery

was not deemed to be at high risk of bias for any assessed domain of study quality. Statistical Analysis Analyses were performed in STATA Version 13 statistical software (StataCorp LP, College Station, Texas). Statistical significance was defined by a 2-tailed p value 18 y of age undergoing major thoracic operation Prior beta-blocker use, asthma, HF, heart block, supraventricular tachyarrhythmias, prior specific drug use (digoxin, quinidine, procainamide, amiodarone, diltiazem, verapamil) Intrathoracic (100

2014 Society for Cardiovascular Angiography and Interventions

110. Cohort of Patients Referred for Brugada Syndrome Investigation in an Electrophysiology Service - 19-Year Registry (PubMed)

-three patients (65.7%) were asymptomatic, 6 (17.14%) had palpitations, 5 (14.3%) had syncope, and 3 (8.6%) had a family history of sudden death. Electrophysiological study induced ventricular tachyarrhythmias in 16 cases (45.7%), the mean ventricular refractory period being 228 ± 36 ms. Ajmaline / procainamide was used in 11 cases (31.4%), changing the ECG pattern to type I in 7 (63.6%). Sixteen cases (45.7%) received an implantable cardioverter defibrillator (ICD). In a mean 5-year follow-up, 1

Full Text available with Trip Pro

2018 Arquivos brasileiros de cardiologia

111. Fluoxetine Opens Window to Improve Motor Recovery After Stroke

, congestive heart failure) Resting blood pressure exceeding 180/100mmHg Requires more than a one person assist for transfer Planned surgery that would affect participation in the trial Participating in another formal lower limbs exercise program more than one day per week History of QT prolongation or concomitant use of clearly identified potential QT prolonging drugs, at the investigators discretion (e.g. amiodarone, bepridil, dysopyramide, dofetilide, flecainide, ibutilide, procainamide, propafenone

2018 Clinical Trials

112. A Clinical Study to Evaluate the Bioavailability Between Two Products Containing Paliperidone 100 mg in the Form of a Prolonged Release Suspension for Injection in Patients With Schizophrenia Who Are Already Stabilized in This Treatment

Antiarrhythmics (e.g., quinidine, disopyramide, procainamide) and class III antiarrhythmics (e.g. amiodarone, sotalol), antihistamines, antipsychotics known to prolong QT interval, and antimalarials (e.g. mefloquine, quinine), tricyclic antidepressants (eg amitriptyline), tetracyclic antidepressants (eg maprotiline). The patient is receiving centrally acting medicinal products e.g. anxiolytics, risperidone, opiates, etc. or alcohol The patient is receiving drugs that induce orthostatic hypotension (e,g other

2018 Clinical Trials

113. Memantine and Post-mastectomy Neuropathic Pain

, Patient with drug treatments evaluated by the investigator to be not compatible with the trial, Patient treated with specific drugs (amantadine, ketamine, dextromethorphan, L-Dopa, dopaminergic, anticholinergic agonists, barbituric, neuroleptic, IMAO, antispastic agents, dantrolen or baclofen, phenytoin, cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine, hydrochlorothiazide, warfarine), Patient with alcohol addiction, Epileptic patient or history of epileptic seizure or convulsions

2018 Clinical Trials

114. Drug-induced lupus erythematosus: an update on drugs and mechanisms. (PubMed)

%) involved in subacute cutaneous lupus erythematosus, with an observed higher incidence in female patients. Enhanced neutrophil extracellular trap (NET) formation induced by procainamide and hydralazine could be a new mechanism contributing to the pathogenesis of DILE.The list of drugs implicated in triggering DILE is expanding as new drugs with novel mechanisms of action are being developed. It is important to recognize culprit drugs that may induce lupus erythematosus, as discontinuation usually

2018 Current Opinion in Rheumatology

115. Effect of Baseline Antiarrhythmic Drug on Outcomes With Ablation in Ischemic Ventricular Tachycardia: A VANISH Substudy (Ventricular Tachycardia Ablation Versus Escalated Antiarrhythmic Drug Therapy in Ischemic Heart Disease). (PubMed)

patient on procainamide rather than sotalol). Amio-refractory patients had more renal insufficiency (23.7% versus 10%; P=0.0008), worse New York Heart Association class (82.3% II/III versus 65.5%; P=0.0003), and lower ejection fraction (29±9.7% versus 35.2±11%; P<0.0001). Within the amio-refractory group, ablation resulted in reduction of any ventricular arrhythmia compared with escalated drug therapy (hazard ratio, 0.53; 95% confidence interval, 0.31-0.9), P=0.020). Sotalol-refractory patients had

2018 Circulation. Arrhythmia and electrophysiology

116. Placebo-Controlled, Randomized, SAD Study to Evaluate the Safety, Tolerability, and PK of TBI-223 in Healthy Adults

, sertraline, etc.), bupropion, agents known to prolong the QTc interval (erythromycin, clarithromycin, astemizole, type Ia [quinidine, procainamide, disopyramide] and III [amiodarone, sotalol] anti-arrhythmics, carbamazepine, sulfonylureas, and meperidine). Use of any over-the-counter (OTC) medication, including herbal products and vitamins, within 7 days prior to dosing, except acetaminophen. Up to 3 grams per day of acetaminophen is allowed at the discretion of the Investigator prior to dosing. Use

2018 Clinical Trials

117. Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department

, Fosphenytoin, Halothane, Nadolol, Oxprenolol, Pentazocine, Propafenone Subject is on class I antiarrhythmics therapy (including lidocaine, procainamide, disopyramide etc) Subject has injuries requiring splint/casting where patient may not be able to reach the area of greatest pain to apply and reapply the patch Subject has prior history of chronic pain in the affected area (defined as greater than or equal to 6 weeks of pain) Subject has received opioid medication in triage area or within 4 hours

2018 Clinical Trials

118. Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis

treatment with monoamine oxidase inhibitors or in the preceding 14 days Current treatment with linezolid (self-report or by chart review) Current treatment with other drugs that are inhibitors of CYP3A4 (e.g., itraconazole, clarithromycin, voriconazole), or known to prolong QT interval including Class 1A antiarrhythmics (e.g., quinidine, procainamide) or Class 3 antiarrhythmics (e.g., amiodarone, sotalol), antipsychotic medications (ziprasidone, chlorpromazine, thioridazine), and quinolone antibiotics

2018 Clinical Trials

119. Anamorelin Hydrochloride in Reducing Anorexia in Participants With Advanced Non-small Cell Lung Cancer

or diaphragm) with spermicide Uncontrolled diabetes mellitus (fasting blood sugar > 200 mg/dl) at screening Patients on drugs with strong CYP 3A4 inhibitors within the previous two weeks (ketoconazole, clarithromycin, itraconazole, nefazodone, telithromycin) Patients on drugs that may prolong the PR or QRS interval durations, such as any of the class I/sodium (Na+) channel blocking antiarrhythmic medications should be avoided (e.g. flecainide, procainamide, propafenone, quinidine) Patients currently

2018 Clinical Trials

120. BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

. These include but are not limited to Class I antiarrhythmics (eg, quinidine, procainamide, dysopiramide, lidocaine, phenytoin, mexiletine, tocainide, flecainide, propafenone, moricizine), Grapefruit and Seville oranges. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its identifier (NCT

2018 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>