How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

126 results for

Primitive Defenses

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Primitive Defenses

Primitive Defenses Primitive Defenses Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Primitive Defenses Primitive Defenses Aka (...) : Primitive Defenses From Related Chapters II. Types: Primitive Blocking "I can't say or remember that" Introjection "I'll use that trick" Transference "You're like my father who never cared for me" Countertransference "The patient is crazy; I won't deal with him" III. Types: Ordinary Displacement the bear instead of your parents Inhibition Did not work before, might not work now Reaction formation Repression-of emotion Sexualization Externalization Intellectualization Its possible that one might

2018 FP Notebook

2. Vulnerability of primitive human placental trophoblast to Zika virus (PubMed)

differentiated from embryonic stem cells (ESC). The latter appear to be analogous to the primitive placenta formed during implantation. The cells from term placentas, which resist infection, do not express genes encoding most attachment factors implicated in ZIKV entry but do express many genes associated with antiviral defense. By contrast, the ESC-derived trophoblasts possess a wide range of attachment factors for ZIKV entry and lack components of a robust antiviral response system. These cells (...) Vulnerability of primitive human placental trophoblast to Zika virus Infection of pregnant women by Asian lineage strains of Zika virus (ZIKV) has been linked to brain abnormalities in their infants, yet it is uncertain when during pregnancy the human conceptus is most vulnerable to the virus. We have examined two models to study susceptibility of human placental trophoblast to ZIKV: cytotrophoblast and syncytiotrophoblast derived from placental villi at term and colonies of trophoblast

Full Text available with Trip Pro

2017 Proceedings of the National Academy of Sciences of the United States of America

3. Primitive Defenses

Primitive Defenses Primitive Defenses Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Primitive Defenses Primitive Defenses Aka (...) : Primitive Defenses From Related Chapters II. Types: Primitive Blocking "I can't say or remember that" Introjection "I'll use that trick" Transference "You're like my father who never cared for me" Countertransference "The patient is crazy; I won't deal with him" III. Types: Ordinary Displacement the bear instead of your parents Inhibition Did not work before, might not work now Reaction formation Repression-of emotion Sexualization Externalization Intellectualization Its possible that one might

2015 FP Notebook

4. In defense of Sigmund Freud

In defense of Sigmund Freud In defense of Sigmund Freud In defense of Sigmund Freud | | November 10, 2017 49 Shares As a medical student, I immortalized myself with my classmates when I informed a lecturing psychiatry professor that I considered Freud’s theories slightly more credible than the nuns’ tales about guardian angels. The lecturer ignored my obnoxious comment and continued his lecture. But Freudians have been on the defensive for the past decade. This trend culminated when the Library (...) through therapy was better than resorting to violence or substance abuse. Neuropsychiatrists who prefer Prozac, Xanax and Elavil to psychotherapy miss the point. Yes, these drugs alter the brain chemistry, but on a primitive level that is poorly understood. Furthermore, what happens to the brain chemistry with psychotherapy? When a patient alters his behavior in response to a psychiatrist’s analysis, a biochemical change in the brain is occurring too. A patient who decides to be more assertive has

2017 KevinMD blog

5. Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense Mechanism (PubMed)

thought, about 1.3 billion years ago. Amazingly, using extrusion of DNA as a weapon to capture and kill uningestable microbes has its rationale. During the emergence of multicellularity, a primitive innate immune system developed in the form of a dedicated set of specialized phagocytic cells. This professionalization of immunity allowed the evolution of sophisticated defense mechanisms including the sacrifice of a small set of cells by a mechanism related to NETosis. This altruistic behavior likely (...) Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense Mechanism Since the discovery of the formation of DNA-based extracellular traps (ETs) by neutrophils as an innate immune defense mechanism (1), hundreds of articles describe the involvement of ETs in physiological and pathological human and animal conditions [reviewed in Ref. (2), and the previous Frontiers Research Topic on NETosis: http://www.frontiersin.org/books

Full Text available with Trip Pro

2016 Frontiers in immunology

6. Evolution of the complement system: from defense of the single cell to guardian of the intravascular space (PubMed)

Evolution of the complement system: from defense of the single cell to guardian of the intravascular space The complement system is an evolutionarily ancient component of immunity that revolves around the central component C3. With the recent description of intracellular C3 stores in many types of human cells, our view of the complement system has expanded. In this article, we hypothesize that a primitive version of C3 comprised the first element of the original complement system and initially

Full Text available with Trip Pro

2016 Immunological reviews

7. Behavioral responses to a repetitive shadow stimulus express a persistent state of defensive arousal in Drosophila (PubMed)

Behavioral responses to a repetitive shadow stimulus express a persistent state of defensive arousal in Drosophila The neural circuit mechanisms underlying emotion states remain poorly understood. Drosophila offers powerful genetic approaches for dissecting neural circuit function, but whether flies exhibit emotion-like behaviors has not been clear. We recently proposed that model organisms may express internal states displaying "emotion primitives," which are general characteristics common (...) to different emotions, rather than specific anthropomorphic emotions such as "fear" or "anxiety." These emotion primitives include scalability, persistence, valence, and generalization to multiple contexts. Here, we have applied this approach to determine whether flies' defensive responses to moving overhead translational stimuli ("shadows") are purely reflexive or may express underlying emotion states. We describe a new behavioral assay in which flies confined in an enclosed arena are repeatedly exposed

Full Text available with Trip Pro

2015 Current biology : CB

8. The Role of Innate Immunity in Osteoarthritis: When Our First Line of Defense Goes On the Offensive. (PubMed)

immune system, the older or more primitive part of the body's immune defense mechanisms. The roles of some of the components of the innate immune system have been tested in OA models in vivo including the roles of synovial macrophages and the complement system. This review is a selective overview of a large and evolving field. Insights into these mechanisms might inform our ability to identify patient subsets and give hope for the advent of novel OA therapies. (...) The Role of Innate Immunity in Osteoarthritis: When Our First Line of Defense Goes On the Offensive. Although osteoarthritis (OA) has existed since the dawn of humanity, its pathogenesis remains poorly understood. OA is no longer considered a "wear and tear" condition but rather one driven by proteases where chronic low-grade inflammation may play a role in perpetuating proteolytic activity. While multiple factors are likely active in this process, recent evidence has implicated the innate

Full Text available with Trip Pro

2015 Journal of Rheumatology

9. Orientations of psychotic activity in defensive pathological organizations. (PubMed)

Orientations of psychotic activity in defensive pathological organizations. The author reviews some clinical experiences of the treatment of personality disordered patients suffering from internal domination of ego functioning by a defensive pathological organization. In particular, the function and purpose of perverse, sadistic attacks by the organization on the ego are considered and questions pertaining to technique are raised. It is suggested that different forms of sadistic, subjugating (...) , to avoid emotion and to use coercion to enforce a primitive identification by the ego with the psychotic organization in the mind. Certain patients with less severe narcissistic psychopathology, yet for whom object contact can also be associated with the arousal of psychotic anxieties due to intense or persistent conflict with the object, sometimes expressed as organized sadomasochistic clinging to a punishing and punished object (for example, in certain borderline or depressed patients) exhibit

2014 International Journal of Psycho-Analysis

10. Defense Mechanisms Reported by Patients With Borderline Personality Disorder and Axis II Comparison Subjects Over 16 Years of Prospective Follow-Up: Description and Prediction of Recovery. (PubMed)

/borderline defenses except primitive idealization. In addition, four time-varying defense mechanisms were found to predict time to recovery: humor, acting out, emotional hypochondriasis, and projection.Taken together, these results suggest that the longitudinal defensive functioning of borderline patients is distinct and improves substantially over time. They also suggest that immature defenses are the best predictor of time to recovery. (...) Defense Mechanisms Reported by Patients With Borderline Personality Disorder and Axis II Comparison Subjects Over 16 Years of Prospective Follow-Up: Description and Prediction of Recovery. The authors assessed the defensive functioning of 290 patients with borderline personality disorder and compared it with that of 72 patients with other forms of axis II psychopathology over 16 years of prospective follow-up. They also assessed the relationship between time-varying defenses and recovery from

Full Text available with Trip Pro

2012 American Journal of Psychiatry

11. Eicosapolyenoic acids: Novel MAMPs with reciprocal effect on oomycete-plant defense signaling networks (PubMed)

Eicosapolyenoic acids: Novel MAMPs with reciprocal effect on oomycete-plant defense signaling networks Thirty years ago arachidonic (AA; 20:4 Δ ( 5,8,11,14) ) and eicosapentaenoic (EPA; 20:5 Δ ( 5,8,11,14,17) ) acids were identified as elicitors from the late blight pathogen, Phytophthora infestans, capable of triggering the dramatic shifts in isoprenoid metabolism, defense reactions, and cell death associated with the hypersensitive response of potato to incompatible races of the pathogen. ( 1 (...) ) Among plant pathogens, the capacity for eicosapolyenoic acid synthesis appears to be largely restricted to oomycetes, primitive fungi (e.g., zygomycetes and chytrids), and nematodes. AA and EPA, precursors to eicosanoids that mediate inflammatory responses and serve as critical signals for immune and central nervous system functions in mammals, continue to be compelling molecules for study in plants because of what they may reveal about lipid-based signaling and induced immunity in plant-microbe

Full Text available with Trip Pro

2011 Plant signaling & behavior

12. Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor

Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor (Re-MATCH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01326104 Recruitment Status : Active, not recruiting First Posted : March 30, 2011 Last Update Posted : March 19, 2019 Sponsor

2010 Clinical Trials

13. Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association

into the development of congenital heart defects and may lead to discoveries identifying distinct intercellular signaling pathways and transcriptional regulation in response to injury by the RV in contrast to the LV. Beginning in the third week of embryonic development, the primitive heart tube begins beating and undergoes a series of twisting and folding movements to generate a single primitive ventricle that receives blood from a single atrium and ejects blood through a common outflow tube known as the truncus (...) arteriosus ( ). By the end of the fourth week, a muscular ventricular septum emerges from the floor of the primitive ventricle to form the earliest signs of distinct RVs and LVs. Between the fifth and eighth weeks, ridges within the truncus arteriosus grow into the aorticopulmonary septum, which fuses with the endocardial cushions and muscular interventricular septum to form the membranous septum. At the end of the eighth week, distinct pulmonary and systemic circulations exist. For the remainder

Full Text available with Trip Pro

2018 American Heart Association

14. Psychodynamic Psychotherapy with Children

mechanisms that reduce anxiety and maintain psychological homeostasis. Defenses are transformed in the course of development from primitive, imma- ture defenses to more ?exible, mature defenses. Rigidly held defenses may become maladaptive and interfere with further development. 6. Resistance to psychological change serves to maintain psychic stability although it slows the therapeutic process. 7. Transference, namely the repetition or re-enact- ment in the therapist-patient interaction (...) . Com- munications have multiple meanings. 4. Psychic con?ict is ever present and part of normal development. External con?icts occur between the individual and the social or physi- cal environment when the needs of one con?ict with the other. Internal con?icts occur within the mind. Most typically, internal con?icts occur when the individual’s urges, impulses and de- sires come into con?ict with internalized soci- etal, especially parental, prohibitions. 5. Defenses are unconscious mental

2018 American Academy of Child and Adolescent Psychiatry

15. Evaluation and Management of Right-Sided Heart Failure

by the RV in contrast to the LV. Beginning in the third week of embryonic development, the primitive heart tube begins beating and undergoes a series of twisting and folding movements to generate a single primitive ventricle that receives blood from a single atrium and ejects blood through a common outflow tube known as the truncus arteriosus ( ). By the end of the fourth week, a muscular ventricular septum emerges from the floor of the primitive ventricle to form the earliest signs of distinct RVs (...) migrate to the midline to form a linear heart tube, serving as a scaffold for subsequent heart growth. The heart tube is expanded posteriorly and anteriorly with cells migrating from the secondary heart field, giving rise to the arterial and venous poles. The linear heart tube undergoes a rightward looping, leading to the formation of primitive ventricles and atria. As a result, the venous pole moves anteriorly, positioning the future cardiac chambers for proper development. Heart maturation involves

Full Text available with Trip Pro

2018 International Society for Heart and Lung Transplantation

16. Management of Opioid Therapy (OT) for Chronic Pain

Management of Opioid Therapy (OT) for Chronic Pain VA/DoD CLINICAL PRACTICE GUIDELINE FOR OPIOID THERAPY FOR CHRONIC PAIN Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision making. They are not intended to define a standard of care and should not be construed (...) The Department of Veterans Affairs (VA) and Department of Defense (DoD) Evidence-Based Practice Work Group (EBPWG) was established and first chartered in 2004, with a mission to advise the “…Health Executive Council on the use of clinical and epidemiological evidence to improve the health of the population across the Veterans Health Administration and Military Health System,” by facilitating the development of clinical practice guidelines (CPGs) for the VA and DoD populations.[1] This CPG is intended

2017 VA/DoD Clinical Practice Guidelines

17. Salt Sensitivity of Blood Pressure

tubular Na + reabsorption, all of which are dependent on sympathetic function as shown by reversibility with renal denervation. The effect of varying salt consumption in chimpanzees was an overall increase in BP with high-salt intakes and an overall reduction with low intakes. Interestingly, increases in sodium intake from a magnitude consumed by primitive human societies (35 mmol/d) to levels that would be considered a relatively low-salt diet now in the Western world (120 mmol/d) were enough

Full Text available with Trip Pro

2016 American Heart Association

18. Got diarrhea? The latest trend in fashionable nonsense is “raw water”

flourished from, since the beginning of our existance. We trust it’s perfect just the way it is. “We trust it’s perfect just the way it is” basically because it’s “natural.” Also notice the distinct tinge of primitive vitalism in the claims made for this water, which is portrayed as an “ancient life source.” That vitalism is made even more explicit in multiple Instagram posts like this one: A post shared by (@livespringwater) on Dec 18, 2017 at 11:48am PST “Our earth provides us this ancient source (...) not a lot about vaccines on his website, but he does clearly believe that vaccines somehow “damage” the gut bacteria, with detrimental health consequences to infants and children. He also thinks that you , claiming: Vaccines deliver either live or dead viruses directly into your body tissue, short-circuiting your body’s normal front-line immune defense system in your respiratory passageways and mucous membrane linings. If your immune system is weak or out of balance when the virus is introduced this way

2018 Respectful Insolence

19. "The Root Cause" Netflix Documentary & Psuedoscience: A Recipe for Confusion

. Weston Price 1870-1948 The documentary references the work of Dr. Weston Price in the 1920's and the resulting focal infection theory. While Dr. Price's research was creative at the time, it was primitive and would never stand up to modern scientific standards for research. His research, done in the dawn of what we would call modern microbiology, is still quoted by biological dentists, such as Joseph Mercola, George Meinig and the others in this documentary, as the evidence to support their claims (...) protect our nasal cavity from what’s going on outside in our environment? No, it’s all because of the microorganisms. That’s our first line of defense. But in medical school, they teach our first line of defense is macrophages, antibodies, neutrophils. That is not true! Our first line of defense are microorganisms, so we better start loving them again! When I was the director of periodontics, we did lots of periodontal surgery. We never gave antibiotics to patients after periodontal surgery and nobody

2019 The Endo Blog

20. Childhood Soft Tissue Sarcoma Treatment (PDQ®): Patient Version

mertansine is an antibody-drug conjugate being studied for the treatment of , malignant peripheral nerve sheath tumor, and synovial sarcoma. See for more information. Immunotherapy is a treatment that uses the patient’s to fight disease. Substances made by the body or made in a laboratory are used to boost, direct, or restore the body’s natural defenses against disease. is a type of immunotherapy used to treat epithelioid hemangioendothelioma. It interferes with the division of tumor cells and can slow (...) , , and surgery with or without . Primitive neuroectodermal tumor (PNET)/extraskeletal Ewing tumor See the summary on . Synovial sarcoma Treatment of may include the following: . and/or may be given before or after surgery. Chemotherapy. A of . A clinical trial of , radiation therapy, and surgery with or without chemotherapy. A clinical trial of targeted therapy (histone methyltransferase inhibitor). A clinical trial of an . Undifferentiated/unclassified sarcoma These include undifferentiated pleomorphic

2017 PDQ - NCI's Comprehensive Cancer Database

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>