How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

5,322 results for

Primary Amenorrhea

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Assessment of primary amenorrhoea

for at least 3 cycles of her previous interval, or lack of menses for 6 months in a patient who was previously menstruating. Although overlapping attributes exist between the two groups, the diagnostic approaches vary significantly. Primary amenorrhoea is rare: about 0.3% of women fail to establish menstruation. Kiningham RB, Apgar BS, Schwenk TL. Evaluation of amenorrhea. Am Fam Physician. 1996;53:1185-1194. http://www.ncbi.nlm.nih.gov/pubmed/8629565?tool=bestpractice.com The prevalence of primary (...) amenorrhoea in the US is <0.1%, compared with 4% for secondary amenorrhoea. Timmreck LS, Reindollar RH. Contemporary issues in primary amenorrhea. Obstet Gynecol Clin North Am. 2003;30:287-302. http://www.ncbi.nlm.nih.gov/pubmed/12836721?tool=bestpractice.com Pettersson F, Fries H, Nillius SJ. Epidemiology of secondary amenorrhea: incidence and prevalence rates. Am J Obstet Gynecol. 1973;117:80-86. http://www.ncbi.nlm.nih.gov/pubmed/4722382?tool=bestpractice.com Even when causes of primary and secondary

2018 BMJ Best Practice

2. Assessment of secondary amenorrhoea

%), and ballet dancers (19% to 44%). Kiningham RB, Apgar BS, Schwenk TL. Evaluation of amenorrhea. Am Fam Physician. 1996 Mar;53(4):1185-94. http://www.ncbi.nlm.nih.gov/pubmed/8629565?tool=bestpractice.com The prevalence of primary amenorrhoea in the US is <0.1%, compared with 3% to 4% for secondary amenorrhoea. Practice Committee of the American Society for Reproductive Medicine. Current evaluation of amenorrhea. Fertil Steril. 2008 Nov;90(suppl 5):S219-25. https://www.fertstert.org/article/S0015-0282(08 (...) Assessment of secondary amenorrhoea Assessment of secondary amenorrhoea - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of secondary amenorrhoea Last reviewed: February 2019 Last updated: December 2018 Summary Amenorrhoea is the transient or permanent absence of menstrual flow. There is no consensus on the definition of amenorrhoea, but it may be subdivided into primary and secondary presentations

2018 BMJ Best Practice

3. Assessment of secondary amenorrhoea

%), and ballet dancers (19% to 44%). Kiningham RB, Apgar BS, Schwenk TL. Evaluation of amenorrhea. Am Fam Physician. 1996 Mar;53(4):1185-94. http://www.ncbi.nlm.nih.gov/pubmed/8629565?tool=bestpractice.com The prevalence of primary amenorrhoea in the US is <0.1%, compared with 3% to 4% for secondary amenorrhoea. Practice Committee of the American Society for Reproductive Medicine. Current evaluation of amenorrhea. Fertil Steril. 2008 Nov;90(suppl 5):S219-25. https://www.fertstert.org/article/S0015-0282(08 (...) Assessment of secondary amenorrhoea Assessment of secondary amenorrhoea - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of secondary amenorrhoea Last reviewed: February 2019 Last updated: December 2018 Summary Amenorrhoea is the transient or permanent absence of menstrual flow. There is no consensus on the definition of amenorrhoea, but it may be subdivided into primary and secondary presentations

2018 BMJ Best Practice

4. The role of electrocardiogram in sex verification in a young adult with primary amenorrhea: a case report Full Text available with Trip Pro

The role of electrocardiogram in sex verification in a young adult with primary amenorrhea: a case report The use of electrocardiogram for sex verification in adults is an emerging concept in medicine. It is feasible through the utilization of Ogunlade Sex Determination Electrocardiographic Score. The aim of this study was to use an electrocardiogram to verify the sex of a woman with primary amenorrhea.We report a case of a 36-year-old woman of Yoruba ethnicity who presented with primary (...) for the SRY gene confirming the status as male. This synchronized with the initial electrocardiogram evaluation. The testes were later removed.This report concluded that an electrocardiogram as a cheap, readily available and non-invasive test has a role in sex verification in young adults with primary amenorrhea.

2018 Journal of medical case reports

5. A novel, homozygous mutation in desert hedgehog (DHH) in a 46, XY patient with dysgenetic testes presenting with primary amenorrhoea: a case report Full Text available with Trip Pro

A novel, homozygous mutation in desert hedgehog (DHH) in a 46, XY patient with dysgenetic testes presenting with primary amenorrhoea: a case report Desert hedgehog (DHH) mutations have been described in only a limited number of individuals with 46, XY disorders of sex development (DSD) presenting as either partial or complete gonadal dysgenesis. Gonadal tumours and peripheral neuropathy have been associated with DHH mutations. Herein we report a novel, homozygous mutation of DHH identified (...) through a targeted, massively parallel sequencing (MPS) DSD panel, in a patient presenting with partial gonadal dysgenesis. This novel mutation is two amino acids away from a previously described mutation in a patient who presented with complete gonadal dysgenesis. Adding to the complexity of work-up, our patient also expressed gender identity concern.A 14-year-old, phenotypic female presented with primary amenorrhoea and absent secondary sex characteristics. Investigations revealed elevated

2018 International journal of pediatric endocrinology

6. Functional Hypothalamic Amenorrhea

, and/or skeletal fragility. (2|⊕⊕⊕⚪) 2.8 In cases of primary amenorrhea, we suggest evaluating Müllerian tract anomalies (congenital or acquired). Diagnostic options include physical examination, progestin challenge test, abdominal or transvaginal ultrasound, and/or MRI, depending on the context and patient preferences. (2|⊕⊕⊕⚪) 2.9 In patients with FHA and underlying polycystic ovary syndrome (PCOS), we suggest: a baseline BMD measurement by DXA in those with 6 or more months of amenorrhea and earlier (...) Functional Hypothalamic Amenorrhea '); '); Hypothalamic Amenorrhea Guideline Resources | Endocrine Society Hormone Science to Health / › › › Guidelines and Clinical Practice Section + Hypothalamic Amenorrhea Guideline Resources Full Guideline: JCEM | March 2017 Catherine M. Gordon (chair), Kathryn E. Ackerman, Sarah L. Berga, Jay R. Kaplan, George Mastorakos, Madhusmita Misra, M. Hassan Murad, Nanette F. Santoro, and Michelle P. Warren The 2017 guideline addresses: Diagnosing functional

2017 The Endocrine Society

7. Lactational amenorrhoea method for family planning. Full Text available with Trip Pro

LAM and being supported in doing so, and fully breastfeeding amenorrheic women not using any method. As the length of lactation amenorrhoea in women using LAM differed greatly between the populations studied, and was population specific, it is uncertain whether LAM extends lactational amenorrhoea. (...) Lactational amenorrhoea method for family planning. It is estimated that about 40% of pregnancies in the world are unintended and that the major part of these are unwanted. There are several reasons no or ineffective contraception is used to prevent these pregnancies, including difficulty in obtaining contraceptives. The lactational amenorrhoea method (LAM) is a contraceptive method where the mother is informed and supported in how to use breastfeeding for contraception. LAM is available

2015 Cochrane

8. Balanced Reciprocal Translocation t(X;1) in a Girl with Tall Stature and Primary Amenorrhea Full Text available with Trip Pro

Balanced Reciprocal Translocation t(X;1) in a Girl with Tall Stature and Primary Amenorrhea Chromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. Although X-autosome translocations are frequently associated with streak gonads and clinical features of the Turner syndrome, the majority of X-autosome carriers may present with a variable phenotype, developmental delay, and recognizable X-linked syndrome due to nonrandom X (...) -inactivation. In this article, we describe a healthy 15.5-year-old girl with primary amenorrhea, gonadal dysgenesis, and tall stature without other manifestations of the Turner syndrome. Relevant clinical, biochemical, endocrinological, and cytogenetical evaluations were performed. Initial investigations revealed hypergonadotropic hypogonadism (FSH=134 mIU/mL [normal=10-15 mIU/mL], LH=47.5 [normal=10-15 mIU/mL], and estradiol=24.3 pmol/L). On ultrasound examination of the pelvis, streak ovaries

2017 Iranian journal of medical sciences

9. Using kisspeptin to assess GnRH function in an unusual case of primary amenorrhoea Full Text available with Trip Pro

Using kisspeptin to assess GnRH function in an unusual case of primary amenorrhoea Primary amenorrhoea is defined as the failure to commence menstruation by the age of 15 years, in the presence of normal secondary sexual development. The potential causes of primary amenorrhoea extend from structural to chromosomal abnormalities. Polycystic ovarian syndrome (PCOS) is a common cause of secondary amenorrhoea but an uncommon cause of primary amenorrhoea. An early and prompt diagnosis of PCOS (...) is important, as up to 30% of these women are predisposed to glucose intolerance and obesity, with the subgroup of women presenting with primary amenorrhoea and PCOS displaying a higher incidence of metabolic dysfunction. We describe a case of an 18-year-old female presenting with primary amenorrhoea of unknown aetiology. Although initial investigations did not demonstrate clinical or biochemical hyperandrogenism or any radiological evidence of polycystic ovaries, a raised luteinising hormone (LH

2017 Endocrinology, diabetes & metabolism case reports

10. Spectrum of MRI Appearance of Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome in Primary Amenorrhea Patients Full Text available with Trip Pro

Spectrum of MRI Appearance of Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome in Primary Amenorrhea Patients Mayer-Rokitansky-Kuster-Hauser (MRKH) synd-rome is a malformation in female genital tract due to interrupted embryonic development of para-mesonephric ducts leading to uterine and proximal vagina aplasia or hypoplasia.To analyse the MRI findings in females suspected of MRKH syndrome in a primary amenorrhea workup.A cross-sectional study comprising of 11 patients of MRKH syndrome presented

2017 Journal of clinical and diagnostic research : JCDR

11. Late Diagnosis of 5-α-Reductase Type 2 Deficiency in an Adolescent Girl with Primary Amenorrhoea Full Text available with Trip Pro

Late Diagnosis of 5-α-Reductase Type 2 Deficiency in an Adolescent Girl with Primary Amenorrhoea Deficiency of the 5-α-reductase enzyme has been found to affect male sexual development. We report an 18-year-old patient who was referred to an endocrinology clinic in Jizan, Saudi Arabia, in April 2014 with primary amenorrhoea, virilisation and a lack of secondary sex characteristics. As female external genitalia were present at birth, she had been raised as a female. Magnetic resonance imaging

2017 Sultan Qaboos University medical journal

12. Primary Amenorrhea

Amenorrhoe , Primaere Amenorrhoe Italian Amenorrea primaria Portuguese Amenorreia primária Spanish Amenorrea primaria , amenorrea fisiológica primaria (hallazgo) , amenorrea fisiológica primaria , amenorrea primaria Japanese 原発性無月経 , 原発性無月経症 , ゲンパツセイムゲッケイショウ , ゲンパツセイムゲッケイ English primary amenorrhea , primary amenorrhea (diagnosis) , Amenorrhoea primary , amenorrhea primary , Amenorrhea, primary , Primary amenorrhoea (finding) , Primary Amenorrhea , Delayed Menarche , Primary physiologic amenorrhea (...) ) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Primary physiologic amenorrhea (C0232939) Definition (NCI) Abnormally late or absent menarche in a female with normal secondary sexual characteristics.(NICHD) Concepts Disease or Syndrome ( T047 ) ICD10 SnomedCT 156035004 , 8913004 Dutch primaire amenorroe , amenorroe; primair , primair; amenorroe , Primaire amenorroe French Aménorrhée primaire , Aménorrhée primitive German Amenorrhoe primaer , primaere

2018 FP Notebook

13. Amenorrhoea

Amenorrhoea Amenorrhoea - NICE CKS Share Amenorrhoea: Summary Amenorrhoea is the absence or cessation of menstruation. Primary amenorrhoea is defined as the failure to establish menstruation by 15 years of age in girls with normal secondary sexual characteristics (such as breast development), or by 13 years of age in girls with no secondary sexual characteristics. Secondary amenorrhoea is defined as the cessation of menstruation for 3–6 months in women with previously normal and regular menses (...) , or for 6–12 months in women with previous oligomenorrhoea. Causes of primary amenorrhoea include: In those with normal secondary sexual characteristics — physiological causes (constitutional delay and pregnancy), genito-urinary malformations (such as imperforate hymen, transverse septum, and absent vagina or uterus), and endocrine disorders (such as hypothyroidism, hyperthyroidism, hyperprolactinaemia, and Cushing's syndrome). In those with no secondary sexual characteristics — primary ovarian

2018 NICE Clinical Knowledge Summaries

14. Treatment of postpill amenorrhea with abdominal obesity by traditional Korean medicine treatment focused on pharmacopuncture and moxibustion: A case report. Full Text available with Trip Pro

Treatment of postpill amenorrhea with abdominal obesity by traditional Korean medicine treatment focused on pharmacopuncture and moxibustion: A case report. Hormone imbalance and menstrual irregularities are normal for postpill women. Pharmacopuncture and moxibustion can stimulate acupoints with herbal extract and heat, respectively, to regulate the function of qi and blood, expel pathogens, and support health.A 39-year-old female patient presented with amenorrhea, >6 months after she had (...) stopped taking the oral contraceptive pill, which she had taken for more than 10 years, and possible associated infertility. Additionally, she reported sudden weight gain of approximately 12 kg in 1 year.In this study, we examined the amenorrhea lasted more than 6 months for postpill patient.She refused a strong acupuncture stimulus; she underwent lower abdomen pharmacopuncture with wild ginseng complex (WGC) and moxibustion at CV4, 5 times during 1 month. As a secondary treatment, 1 g Geoseub-hwan

2019 Medicine

15. Müllerian Agenesis Masquerading as Secondary Amenorrhea Full Text available with Trip Pro

Müllerian Agenesis Masquerading as Secondary Amenorrhea The most common cause of primary amenorrhea is congenital malformation of the Müllerian ducts, including Müllerian agenesis, also known as Mayer-Rokitansky-Küster-Hauser syndrome (MRKH). Most general gynecologists and primary care physicians who see female adolescents will encounter MRKH in their careers. We present the case of an adolescent with MRKH who reported secondary, instead of primary amenorrhea. We discuss the subtleties

2018 Case reports in pediatrics

16. FXPOI: Pattern of AGG Interruptions Does not Show an Association With Age at Amenorrhea Among Women With a Premutation Full Text available with Trip Pro

FXPOI: Pattern of AGG Interruptions Does not Show an Association With Age at Amenorrhea Among Women With a Premutation Fragile X-associated primary ovarian insufficiency (FXPOI) occurs in about 20% of women who carry a premutation allele (55-200 CGG repeats). These women develop hypergonadotropic hypogonadism and have secondary amenorrhea before age 40. A non-linear association with repeat size and risk for FXPOI has been seen in multiple studies women with a premutation: those with a mid-range (...) of repeats are at highest risk (∼70-100 CGG repeats). Importantly, not all carriers with 70-100 repeats experience FXPOI. We investigated whether AGG interruptions, adjusted for repeat size, impacted age at secondary amenorrhea. We have reproductive history information and AGG interruption data on 262 premutation women: 164 had an established age at amenorrhea (AAA) (for some, age at onset of FXPOI) or menopause, 16 had a surgery involving the reproductive system such as a hysterectomy, and 82 women were

2018 Frontiers in genetics

17. Bone accrual in oligo-amenorrheic athletes, eumenorrheic athletes and non-athletes. Full Text available with Trip Pro

Bone accrual in oligo-amenorrheic athletes, eumenorrheic athletes and non-athletes. Mechanical loading improves bone mineral density (BMD) and strength while decreasing fracture risk. Cross-sectional studies show that exercise advantage is lost in oligo-amenorrheic athletes (OA). Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents/young adults.Evaluate differences in bone accrual over 12 months in OA, eumenorrheic athletes (EA (...) and tibia was assessed using microfinite element analysis of data obtained via high resolution peripheral quantitative computed tomography (HRpQCT). The primary analysis was a comparison of changes in areal BMD, BMC, and failure load across groups over 12-months at the respective sites.Groups did not differ for baseline age, height or BMI. Percent body fat was lower in both OA and EA compared to NA. OA attained menarche later than EA and NA. Over the follow-up period, OA gained 1.9 ± 2.7 kg of weight

2018 Bone

18. Description of Practices Implemented in the Birth of Living Children Before 24 Weeks of Amenorrhea

Implemented in the Birth of Living Children Before 24 Weeks of Amenorrhea Estimated Study Start Date : February 2018 Estimated Primary Completion Date : August 2020 Estimated Study Completion Date : August 2020 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Intervention Details: Behavioral: Asking caregivers in their practice A questionary is given to caregivers Outcome Measures Go to Primary Outcome Measures : Existence of cardiac activity [ Time (...) Description of Practices Implemented in the Birth of Living Children Before 24 Weeks of Amenorrhea Description of Practices Implemented in the Birth of Living Children Before 24 Weeks of Amenorrhea - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2018 Clinical Trials

19. Chromosomal abnormalities and hormonal disorders of primary amenorrhea patients in Egypt Full Text available with Trip Pro

Chromosomal abnormalities and hormonal disorders of primary amenorrhea patients in Egypt Primary amenorrhea is defined as the absence of menstruation and secondary sexual characteristics in phenotypic women aged 14 years or older. Hormonal disorders are main causes of primary amenorrhea. Common hormonal cause of primary amenorrhea includes pituitary dysfunction and absent ovarian function. The aim of this study was to estimate the incidence and types of chromosomal abnormalities in patients (...) with primary amenorrhea in Egypt.Chromosomal analysis and hormonal assay were carried out on 223 patients with primary amenorrhea that were referred from different parts of Egypt to Cytogenetic laboratory of Genetic Unit, Children Hospital Mansoura University, from July 2008 to December 2010. FISH technique was carried out in some of cases to more evaluation.The frequency of chromosomal abnormalities was 46 (20.63%) in primary amenorrhea patients. The chromosomal abnormalities can be classified into four

2012 Indian journal of human genetics

20. Primary amenorrhea after bone marrow transplantation and adjuvant chemotherapy misdiagnosed as disorder of sex development: A case report. Full Text available with Trip Pro

Primary amenorrhea after bone marrow transplantation and adjuvant chemotherapy misdiagnosed as disorder of sex development: A case report. Disorders of sex development (DSD) is a congenital condition in which the development of chromosomal, gonadal or genital sex is atypical. Majority of patients present clinical characteristics of primary amenorrhea, absent secondary sex characters, and abnormal hormone level. A female appearance patient with primary amenorrhea and 46 XY karyotype seems (...) to be solid evidences to diagnose Y-chromosome-related DSD diseases, while it is not necessarily the accurate diagnosis. We report the case of an 18-year-old girl with primary amenorrhea and 46 XY karyotype misdiagnosed as Y-chromosome-related DSD.The patient has normal female reproductive organs and a disrupted pubertal development after the treatment for acute myeloid leukemia (AML). We consider that her gonads were probably functional and later impaired after AML. The clinical manifestations were

2016 Medicine

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>